Rongtuan Lin


Affiliation: McGill University
Country: Canada


  1. Lin R, Lacoste J, Nakhaei P, Sun Q, Yang L, Paz S, et al. Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage. J Virol. 2006;80:6072-83 pubmed publisher
    ..These observations provide an outline of the mechanism by which hepatitis C virus evades the interferon antiviral response...
  2. Olagnier D, Lababidi R, Hadj S, Sze A, Liu Y, Naidu S, et al. Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity. Mol Ther. 2017;25:1900-1916 pubmed publisher
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    Lin R, Yang L, Arguello M, Penafuerte C, Hiscott J. A CRM1-dependent nuclear export pathway is involved in the regulation of IRF-5 subcellular localization. J Biol Chem. 2005;280:3088-95 pubmed
    ..Although IRF-5 is phosphorylated by IKKepsilon and TBK1 in co-transfected cells, the phosphorylation of IRF-5 did not lead to IRF-5 nuclear localization or activation. ..
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    Lin R, Yang L, Nakhaei P, Sun Q, Sharif Askari E, Julkunen I, et al. Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20. J Biol Chem. 2006;281:2095-103 pubmed
    ..These results suggest that the virus-inducible, NF-kappaB-dependent activation of A20 functions as a negative regulator of RIG-I-mediated induction of the antiviral state. ..
  5. Sze A, Olagnier D, Hadj S, Han X, Tian X, Xu H, et al. Sophoraflavenone G Restricts Dengue and Zika Virus Infection via RNA Polymerase Interference. Viruses. 2017;9: pubmed publisher
    ..These data suggest that Sophoraflavenone G represents a promising candidate regarding anti-Flaviviridae research. ..