Affiliation: McGill University
Lin R, Lacoste J, Nakhaei P, Sun Q, Yang L, Paz S, et al
. Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavage. J Virol. 2006;80:6072-83 pubmed publisher
..These observations provide an outline of the mechanism by which hepatitis C virus evades the interferon antiviral response...
Olagnier D, Lababidi R, Hadj S, Sze A, Liu Y, Naidu S, et al
. Activation of Nrf2 Signaling Augments Vesicular Stomatitis Virus Oncolysis via Autophagy-Driven Suppression of Antiviral Immunity. Mol Ther. 2017;25:1900-1916 pubmed publisher
Lin R, Yang L, Arguello M, Penafuerte C, Hiscott J. A CRM1-dependent nuclear export pathway is involved in the regulation of IRF-5 subcellular localization. J Biol Chem. 2005;280:3088-95 pubmed
..Although IRF-5 is phosphorylated by IKKepsilon and TBK1 in co-transfected cells, the phosphorylation of IRF-5 did not lead to IRF-5 nuclear localization or activation. ..
Lin R, Yang L, Nakhaei P, Sun Q, Sharif Askari E, Julkunen I, et al
. Negative regulation of the retinoic acid-inducible gene I-induced antiviral state by the ubiquitin-editing protein A20. J Biol Chem. 2006;281:2095-103 pubmed
..These results suggest that the virus-inducible, NF-kappaB-dependent activation of A20 functions as a negative regulator of RIG-I-mediated induction of the antiviral state. ..
Sze A, Olagnier D, Hadj S, Han X, Tian X, Xu H, et al
. Sophoraflavenone G Restricts Dengue and Zika Virus Infection via RNA Polymerase Interference. Viruses. 2017;9: pubmed publisher
..These data suggest that Sophoraflavenone G represents a promising candidate regarding anti-Flaviviridae research. ..