Research Topics
| Catherine LimperopoulosSummaryAffiliation: McGill University Country: Canada Publications
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Detail Information
Publications
Autism spectrum disorders in survivors of extreme prematurityCatherine Limperopoulos
Department of Neurology and Neurosurgery, School of Physical and Occupational Therapy, McGill University, 2300 Tupper Street, Montreal, Quebec, H3H 1P3, Canada
Clin Perinatol 36:791-805, vi. 2009..Available evidence linking prematurity and autism spectrum disorders is reviewed in this article...
Predictors of developmental disabilities after open heart surgery in young children with congenital heart defectsCatherine Limperopoulos
School of Physical and Occupational Therapy, Departments of Neurology and Neurosurgery, McGill University-Montreal Children's Hospital, , Canada
J Pediatr 141:51-8. 2002..The cause is multifactorial and includes brain injury before, during, and after heart surgery...
Brain volume and metabolism in fetuses with congenital heart disease: evaluation with quantitative magnetic resonance imaging and spectroscopyCatherine Limperopoulos
Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada
Circulation 121:26-33. 2010..A significant proportion of newborns with complex CHD have abnormalities of brain size, structure, or function, which suggests that antenatal factors may contribute to childhood neurodevelopmental morbidity...- Advanced neuroimaging techniques: their role in the development of future fetal and neonatal neuroprotectionCatherine Limperopoulos
Montreal Children s Hospital, Pediatric Neurology, McGill University, Montreal, Quebec, Canada
Semin Perinatol 34:93-101. 2010..This article will provide an overview of normal and abnormal brain development, and explore the role of advanced neuroimaging techniques in neuroprotective therapies in the neonatal intensive care unit... - Does cerebellar injury in premature infants contribute to the high prevalence of long-term cognitive, learning, and behavioral disability in survivors?Catherine Limperopoulos
Department of Neurology and Neurosurgery and School of Physical and Occupational Therapy, McGill University, Montreal, Quebec, Canada
Pediatrics 120:584-93. 2007..We sought to delineate the potential role of cerebellar hemorrhagic injury in the long-term disabilities of survivors of prematurity... - How accurately does current fetal imaging identify posterior fossa anomalies?Catherine Limperopoulos
Fetal Neonatal Neurology Research Program, Department of Neurology, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
AJR Am J Roentgenol 190:1637-43. 2008..The second objective was to assess the accuracy with which fetal MRI predicts postnatal MRI findings in this population... - Disorders of the fetal circulation and the fetal brainCatherine Limperopoulos
Department of Neurology and Neurosurgery, McGill University, 2300 Tupper Street, Montreal, QC H3H 1P3, Canada
Clin Perinatol 36:561-77. 2009..The progress to date with the application of these techniques is reviewed in this article... - Advancing fetal brain MRI: targets for the futureCatherine Limperopoulos
Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada
Semin Perinatol 33:289-98. 2009.... - Cerebellar injury in term infants: clinical characteristics, magnetic resonance imaging findings, and outcomeCatherine Limperopoulos
Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada
Pediatr Neurol 41:1-8. 2009..Cerebellar injury in the term infant is associated with a broad spectrum of neurodevelopmental disabilities, particularly in infants with large cerebellar lesions... - Positive screening for autism in ex-preterm infants: prevalence and risk factorsCatherine Limperopoulos
Department of Neurology and Neurosurgery, School of Physical and Occupational Therapy, McGill University, Montreal, Quebec, Canada
Pediatrics 121:758-65. 2008..The objective of this study was to perform screening tests for early autistic features in children with a history of very low birth weight and to identify risk factors associated with a positive screening result... - Regional cerebellar volumes predict functional outcome in children with cerebellar malformationsMarie Eve Bolduc
School of Physical and Occupational Therapy, McGill University, Montreal, QC, Canada
Cerebellum 11:531-42. 2012..These results begin to define the structural topography of functional outcome in children with cerebellar malformations and should lead to greater accuracy of prognostication as well as timely early developmental interventions... - Neurodevelopmental outcome in survivors of periventricular hemorrhagic infarctionHaim Bassan
Department of Neurology, Children s Hospital and Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA
Pediatrics 120:785-92. 2007..Our objective was to determine the neurodevelopmental and adaptive outcomes of periventricular hemorrhagic infarction survivors and identify early cranial ultrasound predictors of adverse outcome... - Cerebral hemodynamic changes during intensive care of preterm infantsCatherine Limperopoulos
Department of Neurology and Neurosurgery and School of Physical and Occupational Therapy, McGill University, Montreal, Quebec, Canada
Pediatrics 122:e1006-13. 2008.... - Periventricular hemorrhagic infarction: risk factors and neonatal outcomeHaim Bassan
Department of Neurology, Neonatal Neurology Research Group, Children's Hospital Boston and Harvard Medical School, Boston Massachusetts 02115, USA
Pediatr Neurol 35:85-92. 2006..A growing population of survivors is apparent among infants with birth weight<750 gm. Multiple hemodynamic factors associated with periventricular hemorrhagic infarction cluster in the intrapartum and early neonatal periods... - Impaired trophic interactions between the cerebellum and the cerebrum among preterm infantsCatherine Limperopoulos
Department of Neurology, Children's Hospital, Boston, MA 02115, USA
Pediatrics 116:844-50. 2005..Early-life cerebellar injury may contribute importantly to the high rates of cognitive, behavioral, and motor deficits reported for premature infants... - Spectrum of neurodevelopmental disabilities in children with cerebellar malformationsMarie Eve Bolduc
School of Physical and Occupational Therapy, McGill University, Montreal, Quebec, Canada
Dev Med Child Neurol 53:409-16. 2011..As a result, this has necessitated a greater understanding of the neurodevelopmental consequences of CBMs on child development. The aim of this study was to delineate the impact of CBMs on long-term neurodevelopmental outcomes... - A new look at outcomes of infants with congenital heart diseaseAnnette Majnemer
School of Physical and Occupational Therapy, McGill University, Montreal Children s Hospital McGill University Health Centre, Montreal, Quebec, Canada
Pediatr Neurol 40:197-204. 2009..Lessons learnt from this prospective study are highlighted as well as future directions for research and clinical practice... - Current definitions of hypotension do not predict abnormal cranial ultrasound findings in preterm infantsCatherine Limperopoulos
Department of Neurology, Children s Hospital Boston and Harvard Medical School, Boston, Massachusetts 02115, USA
Pediatrics 120:966-77. 2007..Our goal was to examine the relationship between current definitions of hypotension and early abnormal cranial ultrasound findings... - Late gestation cerebellar growth is rapid and impeded by premature birthCatherine Limperopoulos
Department of Neurology, Children s Hospital Boston and Harvard Medical School, 300 Longwood Ave, Fegan 11, Boston, Massachusetts 02115, USA
Pediatrics 115:688-95. 2005..The objective of this study was to examine the impact of prematurity itself, as well as prematurity-related brain injuries, on early postnatal cerebellar growth with quantitative MRI... - Long-term neuromotor outcome at school entry of infants with congenital heart defects requiring open-heart surgeryAnnette Majnemer
School of Physical and Occupational Therapy, Department of Neurology and Neurosurgery, McGill University, Toronto, Ontario, Canada
J Pediatr 148:72-7. 2006..This prospective study was conducted to investigate whether or not neuromotor impairments evident acutely persist long-term... - Elevated cerebral pressure passivity is associated with prematurity-related intracranial hemorrhageHeather O'Leary
Fetal Neonatal Neurology Research Group, Department of Neurology, and Children s Hospital Boston, Massachusetts 02115, USA
Pediatrics 124:302-9. 2009..We studied the association between the magnitude of cerebral pressure passivity and GM/IVH... - Ultrasonographic features and severity scoring of periventricular hemorrhagic infarction in relation to risk factors and outcomeHaim Bassan
Fetal/Neonatal Neurology Research Group, Department of Neurology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA
Pediatrics 117:2111-8. 2006..Higher severity scores predict worse outcome. Such severity scoring could improve the clinician's ability to counsel parents regarding management decisions and early intervention strategies... - Developmental and functional outcomes at school entry in children with congenital heart defectsAnnette Majnemer
School of Physical and Occupational Therapy, McGill University, Montreal Children s Hospital, Montreal, Quebec, Canada
J Pediatr 153:55-60. 2008..To describe developmental and functional outcomes of children with congenital heart defects (CHDs) at school entry after open heart surgery... - Patterns of use of educational and rehabilitation services at school age for children with congenitally malformed heartsAnnette Majnemer
School of Physical and Occupational Therapy, McGill University MUHC Montreal Children s Hospital, Montreal, Canada
Cardiol Young 18:288-96. 2008..Our objective was to describe the pattern of use of educational supports and rehabilitation services in these children at early school age... - Diagnosis of inferior vermian hypoplasia by fetal magnetic resonance imaging: potential pitfalls and neurodevelopmental outcomeCatherine Limperopoulos
Fetal-Neonatal Neurology Research Group, Department of Neurology, Children's Hospital Boston, Harvard Medical School, Boston, MA, USA
Am J Obstet Gynecol 194:1070-6. 2006..CONCLUSION: Isolated inferior vermian hypoplasia in the second trimester may be over-diagnosed by fetal magnetic resonance imaging and therefore warrants postnatal magnetic resonance imaging confirmation... - Health and well-being of children with congenital cardiac malformations, and their families, following open-heart surgeryAnnette Majnemer
Department of Neurology and Neurosurgery, School of Physical and Occupational Therapy, Montreal Children s Hospital McGill University, Montreal, Quebec, Canada
Cardiol Young 16:157-64. 2006..Our findings suggest that strategies need to be considered to enhance family well-being in the planning and delivery of health services to this population at high risk... - Fluctuating pressure-passivity is common in the cerebral circulation of sick premature infantsJanet S Soul
Department of Neurology, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
Pediatr Res 61:467-73. 2007..Future studies using consistent serial brain imaging are needed to define the relationship between PPI and cerebrovascular injury in the sick premature infant... - Cerebellar malformations alter regional cerebral developmentMarie Eve Bolduc
School of Physical and Occupational Therapy, McGill University, Montreal, QC, Canada
Dev Med Child Neurol 53:1128-34. 2011.... - Early blood gas abnormalities and the preterm brainAlan Leviton
Neuroepidemiology Unit, Neurology Department, Children s Hospital Boston, and Harvard Medical School, Boston, Massachusetts 02215 5724, USA
Am J Epidemiol 172:907-16. 2010..Findings suggest that individual blood gas derangements do not increase brain damage risk. Rather, the multiple derangements associated with indicators of brain damage might be indicators of immaturity/vulnerability and illness severity... - Cerebellar hemorrhage in the preterm infant: ultrasonographic findings and risk factorsCatherine Limperopoulos
Department of Neurology, Children's Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA
Pediatrics 116:717-24. 2005..Predictors of CBH seem to be multifactorial and include combined maternal, intrapartum, and early postnatal factors... - Routine sucrose analgesia during the first week of life in neonates younger than 31 weeks' postconceptional ageC Celeste Johnston
McGill University, School of Nursing, Montreal, QC, Canada
Pediatrics 110:523-8. 2002..To determine the efficacy of sucrose analgesia for procedural pain during the first week of life in preterm neonates in neonatal intensive care units on enhancing later clinical outcomes... - Does bronchopulmonary dysplasia contribute to the occurrence of cerebral palsy among infants born before 28 weeks of gestation?Linda J Van Marter
Newborn Medicine, Children s Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
Arch Dis Child Fetal Neonatal Ed 96:F20-9. 2011..To evaluate the relationships among cerebral palsy (CP) phenotypes and bronchopulmonary dysplasia (BPD) severity and, in the process, to generate hypotheses regarding causal pathways linking BPD to CP... - Cerebellar injury in the premature infant is associated with impaired growth of specific cerebral regionsCatherine Limperopoulos
Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada
Pediatr Res 68:145-50. 2010..These findings suggest that regional cerebral growth impairment results from interruption of cerebellocerebral connectivity and loss of neuronal activation critical for development... - Gender differences in the developmental outcomes of children with congenital cardiac defectsAnnette Majnemer
School of Physical and Occupational Therapy, McGill University, Montreal Children s Hospital McGill University Health Centre, Quebec, Canada
Cardiol Young 22:514-9. 2012..This study compares the developmental and functional outcomes at school entry between boys and girls born with a congenital cardiac defect who required early surgical correction... - Abnormal brain structure and function in newborns with complex congenital heart defects before open heart surgery: a review of the evidenceMallory Owen
McGill University, Neurology and Neurosurgery, Montreal, Quebec, Canada
J Child Neurol 26:743-55. 2011..These findings suggest a fetal or early postnatal onset of impaired brain growth and development. Consequently, reliable methods for early screening and subsequent developmental intervention must be implemented... - Antenatal antecedents of a small head circumference at age 24-months post-term equivalent in a sample of infants born before the 28th post-menstrual weekAlan Leviton
Department of Neurology, Children s Hospital Boston and Harvard Medical School, Boston, MA, USA
Early Hum Dev 86:515-21. 2010..Little is known about the antecedents of microcephaly in early childhood among children born at extremely low gestational age... - Identification of pressure passive cerebral perfusion and its mediators after infant cardiac surgeryHaim Bassan
Department of Neurology, Children's Hospital, 300 Longwood Avenue, Boston MA 02115, USA
Pediatr Res 57:35-41. 2005..001) of autoregulatory failure. This approach provides a means to identify and quantify disturbances of CPA. High CO(2) levels and fluctuating MAP are two important preventable factors associated with disturbed CPA... - Equivalence reliability of the Vineland Adaptive Behavior Scale between in-person and telephone administrationCatherine Limperopoulos
Children's Hospital, Boston, USA
Phys Occup Ther Pediatr 26:115-27. 2006..98) as well as the Adaptive Behavior Composite score (ICC = 0.99). The ability to collect reliable information on a child's developmental progress using a telephone interview format is critical, given current service delivery constraints... - Disorders of cerebellar growth and developmentCatherine Limperopoulos
Neurology and Neurosurgery and School of Physical and Occupational Therapy, McGill University, Montreal, Quebec, Canada
Curr Opin Pediatr 18:621-7. 2006..However, these insights into disturbed structural development demand rigorous examination of their long-term functional significance and caution before their prognostic significance is applied clinically... - Neurodevelopmental outcomes in children with cerebellar malformations: a systematic reviewMarie Eve Bolduc
School of Physical and Occupational Therapy, McGill University, Montreal, Canada
Dev Med Child Neurol 51:256-67. 2009..In summary, rigorous outcome studies describing the spectrum of disabilities in survivors are urgently needed to accurately delineate the long-term neurodevelopmental consequences of cerebellar malformations... - Cerebral near-infrared spectroscopy as a measure of nociceptive evoked activity in critically ill infantsManon Ranger
School of Nursing, McGill University, Montreal, Quebec, Canada
Pain Res Manag 16:331-6. 2011..Nonetheless, until more advanced NIRS techniques emerge, the current devices have strengths that should be exploited... - Nonoral feeding practices for infants in the neonatal intensive care unitRena Birnbaum
Montreal Children s Hospital, 2300 Tupper St, Montreal, QC, Canada
Adv Neonatal Care 9:180-4. 2009..The purpose of this study was to delineate current practice for the selection of nonoral feeding routes in level III neonatal intensive care units (NICUs) across Canada... - Normative fetal brain growth by quantitative in vivo magnetic resonance imagingCedric Clouchoux
Department of Diagnostic Imaging and Radiology, Children s National Medical Center, Washington, DC 20010, USA
Am J Obstet Gynecol 206:173.e1-8. 2012..The objective of the study was to characterize total and regional volumetric brain growth in healthy fetuses during the second and third trimesters of pregnancy, using an automated method... - Importance of outcome determination in pediatric rehabilitationAnnette Majnemer
School of Physical and Occupational Therapy, Montreal Children's Hospital-McGill University, Quebec, Canada
Dev Med Child Neurol 44:773-7. 2002 - The role of rehabilitation specialists in Canadian NICUs: a national surveyCatherine Limperopoulos
School of Physical and Occupational Therapy, McGill University, Montreal Children s Hospital, Montreal, Quebec
Phys Occup Ther Pediatr 22:57-72. 2002..Rehabilitation services, when provided, are comprehensive and include evaluation, treatment, teaching, decision-making, and family support... - How much sucrose is too much sucrose?C Celeste Johnston
Pediatrics 119:226. 2007