Guillaume Lesage

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. ncbi An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae
    Guillaume Lesage
    Department of Biology, McGill University, Montréal PQ H3A 1B1, Canada
    BMC Genet 6:8. 2005
  2. ncbi Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin
    Guillaume Lesage
    Department of Biology, McGill University, Montreal, , Canada
    Genetics 167:35-49. 2004
  3. ncbi A synthetic analysis of the Saccharomyces cerevisiae stress sensor Mid2p, and identification of a Mid2p-interacting protein, Zeo1p, that modulates the PKC1-MPK1 cell integrity pathway
    Robin Green
    Department of Biology, McGill University, Montreal, Quebec, Canada H3A 1B1
    Microbiology 149:2487-99. 2003
  4. ncbi Integrative studies put cell wall synthesis on the yeast functional map
    Arnaud Firon
    Department of Biology, McGill University, Stewart Biology Building, 1205 Dr Penfield Avenue, Montreal, , Canada
    Curr Opin Microbiol 7:617-23. 2004
  5. ncbi Cell wall assembly in Saccharomyces cerevisiae
    Guillaume Lesage
    Department of Biology, McGill University, Montreal, PQ H3A 1B1, Canada
    Microbiol Mol Biol Rev 70:317-43. 2006
  6. ncbi Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7
    Michael R Logan
    Department of Biology, McGill University, Montreal QC, Canada
    BMC Genomics 9:336. 2008
  7. ncbi Motifs, themes and thematic maps of an integrated Saccharomyces cerevisiae interaction network
    Lan V Zhang
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    J Biol 4:6. 2005
  8. ncbi Large-scale analysis of genes that alter sensitivity to the anticancer drug tirapazamine in Saccharomyces cerevisiae
    Karen Hellauer
    Department of Medicine, Royal Victoria Hospital, McGill University, 687 Pine Avenue West, , , Canada H3A 1A1
    Mol Pharmacol 68:1365-75. 2005
  9. ncbi Global mapping of the yeast genetic interaction network
    Amy Hin Yan Tong
    Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada M5G 1L6
    Science 303:808-13. 2004
  10. ncbi trans-Complementation assay establishes the role of proregion hydrophobic amino acid residues in the biosynthesis of Saccharomyces cerevisiae Kex2p endoprotease
    Guillaume Lesage
    , , , Canada
    Yeast 20:397-406. 2003

Collaborators

  • Charles Boone
  • Michael R Logan
  • Christopher Burd
  • Lan V Zhang
  • JASPER D RINE
  • Bernhard Suter
  • Anne-Marie Sdicu
  • Howard Bussey
  • Karen Hellauer
  • Amy Hin Yan Tong
  • Arnaud Firon
  • Robin Green
  • Bernard Turcotte
  • Raffi Tonikian
  • Frederick P Roth
  • Matthias Peter
  • Renee L Brost
  • Brenda Andrews
  • Chris Sander
  • Owen Ryan
  • Gary D Bader
  • Sharyl L Wong
  • James Young
  • Sean Munro
  • Graham Bell
  • Tania Roberts
  • Jennifer Haynes
  • Huiming Ding
  • Bilal Sheikh
  • Michael Chang
  • YiQun Chen
  • Christella Munyana
  • Grant W Brown
  • Hong Xu
  • Nevan Krogan
  • Ainslie B Parsons
  • Hongwei Zhu
  • Grace He
  • Gabriel F Berriz
  • Hong Lu
  • Joshua N Levinson
  • Lizhu Ke
  • Debra S Goldberg
  • Jesse Shapiro
  • Zhijian Li
  • Xiaofeng Xin
  • Helena Friesen
  • Christine Humphries
  • Xin Cheng
  • Anthony Bretscher
  • Shamiza Hussein
  • Gordon Chua
  • Jack Greenblatt
  • Patrice Menard
  • Anne Marie Sdicu

Detail Information

Publications10

  1. ncbi An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae
    Guillaume Lesage
    Department of Biology, McGill University, Montréal PQ H3A 1B1, Canada
    BMC Genet 6:8. 2005
    ....
  2. ncbi Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin
    Guillaume Lesage
    Department of Biology, McGill University, Montreal, , Canada
    Genetics 167:35-49. 2004
    ....
  3. ncbi A synthetic analysis of the Saccharomyces cerevisiae stress sensor Mid2p, and identification of a Mid2p-interacting protein, Zeo1p, that modulates the PKC1-MPK1 cell integrity pathway
    Robin Green
    Department of Biology, McGill University, Montreal, Quebec, Canada H3A 1B1
    Microbiology 149:2487-99. 2003
    ..Thus, MID2 and ZEO1 appear to play reciprocal roles in the modulation of the yeast PKC1-MPK1 cell integrity pathway...
  4. ncbi Integrative studies put cell wall synthesis on the yeast functional map
    Arnaud Firon
    Department of Biology, McGill University, Stewart Biology Building, 1205 Dr Penfield Avenue, Montreal, , Canada
    Curr Opin Microbiol 7:617-23. 2004
    ....
  5. ncbi Cell wall assembly in Saccharomyces cerevisiae
    Guillaume Lesage
    Department of Biology, McGill University, Montreal, PQ H3A 1B1, Canada
    Microbiol Mol Biol Rev 70:317-43. 2006
    ....
  6. ncbi Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7
    Michael R Logan
    Department of Biology, McGill University, Montreal QC, Canada
    BMC Genomics 9:336. 2008
    ..We apply this approach to the conserved type 1 protein phosphatase Glc7, which regulates numerous cellular processes in budding yeast...
  7. ncbi Motifs, themes and thematic maps of an integrated Saccharomyces cerevisiae interaction network
    Lan V Zhang
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    J Biol 4:6. 2005
    ..Recurring patterns of interconnection, or 'network motifs', have revealed biological insights for networks containing either one or two types of interaction...
  8. ncbi Large-scale analysis of genes that alter sensitivity to the anticancer drug tirapazamine in Saccharomyces cerevisiae
    Karen Hellauer
    Department of Medicine, Royal Victoria Hospital, McGill University, 687 Pine Avenue West, , , Canada H3A 1A1
    Mol Pharmacol 68:1365-75. 2005
    ..This suggests that permeases may be involved in intracellular uptake of TPZ. Our discoveries in yeast may lead to a better understanding of TPZ biology in humans...
  9. ncbi Global mapping of the yeast genetic interaction network
    Amy Hin Yan Tong
    Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada M5G 1L6
    Science 303:808-13. 2004
    ..Because digenic interactions are common in yeast, similar networks may underlie the complex genetics associated with inherited phenotypes in other organisms...
  10. ncbi trans-Complementation assay establishes the role of proregion hydrophobic amino acid residues in the biosynthesis of Saccharomyces cerevisiae Kex2p endoprotease
    Guillaume Lesage
    , , , Canada
    Yeast 20:397-406. 2003
    ..In contrast, basic residues K(108) and R(109), located in the C-terminus of the proregion, are not involved in complex formation but are necessary for the biosynthesis of an active enzyme...