Guillaume Lesage

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. pmc An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae
    Guillaume Lesage
    Department of Biology, McGill University, Montréal PQ H3A 1B1, Canada
    BMC Genet 6:8. 2005
  2. pmc Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin
    Guillaume Lesage
    Department of Biology, McGill University, Montreal, Quebec H3A 1B1, Canada
    Genetics 167:35-49. 2004
  3. ncbi request reprint Integrative studies put cell wall synthesis on the yeast functional map
    Arnaud Firon
    Department of Biology, McGill University, Stewart Biology Building, 1205 Dr Penfield Avenue, Montreal, Quebec H3A 1B1, Canada
    Curr Opin Microbiol 7:617-23. 2004
  4. ncbi request reprint A synthetic analysis of the Saccharomyces cerevisiae stress sensor Mid2p, and identification of a Mid2p-interacting protein, Zeo1p, that modulates the PKC1-MPK1 cell integrity pathway
    Robin Green
    Department of Biology, McGill University, Montreal, Quebec, Canada H3A 1B1
    Microbiology 149:2487-99. 2003
  5. pmc Cell wall assembly in Saccharomyces cerevisiae
    Guillaume Lesage
    Department of Biology, McGill University, Montreal, PQ H3A 1B1, Canada
    Microbiol Mol Biol Rev 70:317-43. 2006
  6. pmc Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7
    Michael R Logan
    Department of Biology, McGill University, Montreal QC, Canada
    BMC Genomics 9:336. 2008
  7. pmc Motifs, themes and thematic maps of an integrated Saccharomyces cerevisiae interaction network
    Lan V Zhang
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    J Biol 4:6. 2005
  8. ncbi request reprint Large-scale analysis of genes that alter sensitivity to the anticancer drug tirapazamine in Saccharomyces cerevisiae
    Karen Hellauer
    Department of Medicine, Royal Victoria Hospital, McGill University, 687 Pine Avenue West, Montreal, Quebec, Canada H3A 1A1
    Mol Pharmacol 68:1365-75. 2005
  9. ncbi request reprint Global mapping of the yeast genetic interaction network
    Amy Hin Yan Tong
    Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada M5G 1L6
    Science 303:808-13. 2004
  10. ncbi request reprint trans-Complementation assay establishes the role of proregion hydrophobic amino acid residues in the biosynthesis of Saccharomyces cerevisiae Kex2p endoprotease
    Guillaume Lesage
    Departement de Biochimie, Universite de Montreal, Montreal Quebec H3C 3J7, Canada
    Yeast 20:397-406. 2003

Collaborators

  • Charles Boone
  • Michael R Logan
  • Lan V Zhang
  • JASPER D RINE
  • Bernhard Suter
  • Christopher Burd
  • Anne Marie Sdicu
  • Howard Bussey
  • Karen Hellauer
  • Arnaud Firon
  • Amy Hin Yan Tong
  • Patrice Menard
  • Robin Green
  • Bernard Turcotte
  • Zhijian Li
  • Sean Munro
  • Hong Lu
  • Grant W Brown
  • Raffi Tonikian
  • Matthias Peter
  • Graham Bell
  • Huiming Ding
  • Christine Humphries
  • Xin Cheng
  • Joshua N Levinson
  • Lizhu Ke
  • Owen Ryan
  • Bilal Sheikh
  • Anthony Bretscher
  • Sharyl L Wong
  • Grace He
  • Gary D Bader
  • Shamiza Hussein
  • Nevan Krogan
  • Xiaofeng Xin
  • Michael Chang
  • Renee L Brost
  • Brenda Andrews
  • Debra S Goldberg
  • Gabriel F Berriz
  • Hong Xu
  • Ainslie B Parsons
  • Frederick P Roth
  • James Young
  • Gordon Chua
  • Helena Friesen
  • Jack Greenblatt
  • YiQun Chen
  • Hongwei Zhu
  • Tania Roberts
  • Christella Munyana
  • Jennifer Haynes
  • Chris Sander
  • Jesse Shapiro

Detail Information

Publications10

  1. pmc An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiae
    Guillaume Lesage
    Department of Biology, McGill University, Montréal PQ H3A 1B1, Canada
    BMC Genet 6:8. 2005
    ....
  2. pmc Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofungin
    Guillaume Lesage
    Department of Biology, McGill University, Montreal, Quebec H3A 1B1, Canada
    Genetics 167:35-49. 2004
    ....
  3. ncbi request reprint Integrative studies put cell wall synthesis on the yeast functional map
    Arnaud Firon
    Department of Biology, McGill University, Stewart Biology Building, 1205 Dr Penfield Avenue, Montreal, Quebec H3A 1B1, Canada
    Curr Opin Microbiol 7:617-23. 2004
    ....
  4. ncbi request reprint A synthetic analysis of the Saccharomyces cerevisiae stress sensor Mid2p, and identification of a Mid2p-interacting protein, Zeo1p, that modulates the PKC1-MPK1 cell integrity pathway
    Robin Green
    Department of Biology, McGill University, Montreal, Quebec, Canada H3A 1B1
    Microbiology 149:2487-99. 2003
    ..Thus, MID2 and ZEO1 appear to play reciprocal roles in the modulation of the yeast PKC1-MPK1 cell integrity pathway...
  5. pmc Cell wall assembly in Saccharomyces cerevisiae
    Guillaume Lesage
    Department of Biology, McGill University, Montreal, PQ H3A 1B1, Canada
    Microbiol Mol Biol Rev 70:317-43. 2006
    ....
  6. pmc Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7
    Michael R Logan
    Department of Biology, McGill University, Montreal QC, Canada
    BMC Genomics 9:336. 2008
    ..We apply this approach to the conserved type 1 protein phosphatase Glc7, which regulates numerous cellular processes in budding yeast...
  7. pmc Motifs, themes and thematic maps of an integrated Saccharomyces cerevisiae interaction network
    Lan V Zhang
    Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
    J Biol 4:6. 2005
    ..Recurring patterns of interconnection, or 'network motifs', have revealed biological insights for networks containing either one or two types of interaction...
  8. ncbi request reprint Large-scale analysis of genes that alter sensitivity to the anticancer drug tirapazamine in Saccharomyces cerevisiae
    Karen Hellauer
    Department of Medicine, Royal Victoria Hospital, McGill University, 687 Pine Avenue West, Montreal, Quebec, Canada H3A 1A1
    Mol Pharmacol 68:1365-75. 2005
    ..This suggests that permeases may be involved in intracellular uptake of TPZ. Our discoveries in yeast may lead to a better understanding of TPZ biology in humans...
  9. ncbi request reprint Global mapping of the yeast genetic interaction network
    Amy Hin Yan Tong
    Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada M5G 1L6
    Science 303:808-13. 2004
    ..Because digenic interactions are common in yeast, similar networks may underlie the complex genetics associated with inherited phenotypes in other organisms...
  10. ncbi request reprint trans-Complementation assay establishes the role of proregion hydrophobic amino acid residues in the biosynthesis of Saccharomyces cerevisiae Kex2p endoprotease
    Guillaume Lesage
    Departement de Biochimie, Universite de Montreal, Montreal Quebec H3C 3J7, Canada
    Yeast 20:397-406. 2003
    ..In contrast, basic residues K(108) and R(109), located in the C-terminus of the proregion, are not involved in complex formation but are necessary for the biosynthesis of an active enzyme...