Affiliation: McGill University
- An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiaeGuillaume Lesage
Department of Biology, McGill University, Montréal PQ H3A 1B1, Canada
BMC Genet 6:8. 2005....
- Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofunginGuillaume Lesage
Department of Biology, McGill University, Montreal, , Canada
Genetics 167:35-49. 2004....
- A synthetic analysis of the Saccharomyces cerevisiae stress sensor Mid2p, and identification of a Mid2p-interacting protein, Zeo1p, that modulates the PKC1-MPK1 cell integrity pathwayRobin Green
Department of Biology, McGill University, Montreal, Quebec, Canada H3A 1B1
Microbiology 149:2487-99. 2003..Thus, MID2 and ZEO1 appear to play reciprocal roles in the modulation of the yeast PKC1-MPK1 cell integrity pathway...
- Integrative studies put cell wall synthesis on the yeast functional mapArnaud Firon
Department of Biology, McGill University, Stewart Biology Building, 1205 Dr Penfield Avenue, Montreal, , Canada
Curr Opin Microbiol 7:617-23. 2004....
- Cell wall assembly in Saccharomyces cerevisiaeGuillaume Lesage
Department of Biology, McGill University, Montreal, PQ H3A 1B1, Canada
Microbiol Mol Biol Rev 70:317-43. 2006....
- Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7Michael R Logan
Department of Biology, McGill University, Montreal QC, Canada
BMC Genomics 9:336. 2008..We apply this approach to the conserved type 1 protein phosphatase Glc7, which regulates numerous cellular processes in budding yeast...
- Motifs, themes and thematic maps of an integrated Saccharomyces cerevisiae interaction networkLan V Zhang
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
J Biol 4:6. 2005..Recurring patterns of interconnection, or 'network motifs', have revealed biological insights for networks containing either one or two types of interaction...
- Large-scale analysis of genes that alter sensitivity to the anticancer drug tirapazamine in Saccharomyces cerevisiaeKaren Hellauer
Department of Medicine, Royal Victoria Hospital, McGill University, 687 Pine Avenue West, , , Canada H3A 1A1
Mol Pharmacol 68:1365-75. 2005..This suggests that permeases may be involved in intracellular uptake of TPZ. Our discoveries in yeast may lead to a better understanding of TPZ biology in humans...
- Global mapping of the yeast genetic interaction networkAmy Hin Yan Tong
Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada M5G 1L6
Science 303:808-13. 2004..Because digenic interactions are common in yeast, similar networks may underlie the complex genetics associated with inherited phenotypes in other organisms...
- trans-Complementation assay establishes the role of proregion hydrophobic amino acid residues in the biosynthesis of Saccharomyces cerevisiae Kex2p endoproteaseGuillaume Lesage
, , , Canada
Yeast 20:397-406. 2003..In contrast, basic residues K(108) and R(109), located in the C-terminus of the proregion, are not involved in complex formation but are necessary for the biosynthesis of an active enzyme...