Affiliation: McGill University
- An interactional network of genes involved in chitin synthesis in Saccharomyces cerevisiaeGuillaume Lesage
Department of Biology, McGill University, Montréal PQ H3A 1B1, Canada
BMC Genet 6:8. 2005....
- Analysis of beta-1,3-glucan assembly in Saccharomyces cerevisiae using a synthetic interaction network and altered sensitivity to caspofunginGuillaume Lesage
Department of Biology, McGill University, Montreal, Quebec H3A 1B1, Canada
Genetics 167:35-49. 2004....
- Integrative studies put cell wall synthesis on the yeast functional mapArnaud Firon
Department of Biology, McGill University, Stewart Biology Building, 1205 Dr Penfield Avenue, Montreal, Quebec H3A 1B1, Canada
Curr Opin Microbiol 7:617-23. 2004....
- A synthetic analysis of the Saccharomyces cerevisiae stress sensor Mid2p, and identification of a Mid2p-interacting protein, Zeo1p, that modulates the PKC1-MPK1 cell integrity pathwayRobin Green
Department of Biology, McGill University, Montreal, Quebec, Canada H3A 1B1
Microbiology 149:2487-99. 2003..Thus, MID2 and ZEO1 appear to play reciprocal roles in the modulation of the yeast PKC1-MPK1 cell integrity pathway...
- Cell wall assembly in Saccharomyces cerevisiaeGuillaume Lesage
Department of Biology, McGill University, Montreal, PQ H3A 1B1, Canada
Microbiol Mol Biol Rev 70:317-43. 2006....
- Genetic interaction network of the Saccharomyces cerevisiae type 1 phosphatase Glc7Michael R Logan
Department of Biology, McGill University, Montreal QC, Canada
BMC Genomics 9:336. 2008..We apply this approach to the conserved type 1 protein phosphatase Glc7, which regulates numerous cellular processes in budding yeast...
- Motifs, themes and thematic maps of an integrated Saccharomyces cerevisiae interaction networkLan V Zhang
Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA
J Biol 4:6. 2005..Recurring patterns of interconnection, or 'network motifs', have revealed biological insights for networks containing either one or two types of interaction...
- Large-scale analysis of genes that alter sensitivity to the anticancer drug tirapazamine in Saccharomyces cerevisiaeKaren Hellauer
Department of Medicine, Royal Victoria Hospital, McGill University, 687 Pine Avenue West, Montreal, Quebec, Canada H3A 1A1
Mol Pharmacol 68:1365-75. 2005..This suggests that permeases may be involved in intracellular uptake of TPZ. Our discoveries in yeast may lead to a better understanding of TPZ biology in humans...
- Global mapping of the yeast genetic interaction networkAmy Hin Yan Tong
Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada M5G 1L6
Science 303:808-13. 2004..Because digenic interactions are common in yeast, similar networks may underlie the complex genetics associated with inherited phenotypes in other organisms...
- trans-Complementation assay establishes the role of proregion hydrophobic amino acid residues in the biosynthesis of Saccharomyces cerevisiae Kex2p endoproteaseGuillaume Lesage
Departement de Biochimie, Universite de Montreal, Montreal Quebec H3C 3J7, Canada
Yeast 20:397-406. 2003..In contrast, basic residues K(108) and R(109), located in the C-terminus of the proregion, are not involved in complex formation but are necessary for the biosynthesis of an active enzyme...