Research Topics
| N Lamarche-VaneSummaryAffiliation: McGill University Country: Canada Publications
|
Detail Information
Publications
CdGAP, a novel proline-rich GTPase-activating protein for Cdc42 and RacN Lamarche-Vane
Medical Research Council Laboratory for Molecular Cell Biology, CRC Oncogene and Signal Transduction Group, University College London, Gower Street, London WC1E 6BT, United Kingdom
J Biol Chem 273:29172-7. 1998..Thus, CdGAP is a novel GAP that is likely to participate in Cdc42- and Rac-induced signaling pathways leading to actin reorganization...
Activation of the small GTPase Rac is sufficient to disrupt cadherin-dependent cell-cell adhesion in normal human keratinocytesV M Braga
Medical Research Council Laboratory for Molecular Cell Biology and the Department of Biochemistry and Molecular Biology, University College London, London WC1E 6BT, United Kingdom
Mol Biol Cell 11:3703-21. 2000..Because Rac activity is also necessary for migration, Rac is a good candidate to coordinately regulate cell-cell and cell-substratum adhesion during tumorigenesis...
Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoAS K Prakash
Departments of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
Hum Mol Genet 9:477-88. 2000..These results suggest that ARHGAP6 has two independent functions: one as a GAP with specificity for RhoA and the other as a cytoskeletal protein that promotes actin remodeling...
Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASPN K Hussain
Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, H3A 2B4, Canada
Nat Cell Biol 3:927-32. 2001..These studies reveal a role for intersectin-l in a novel mechanism of N-WASP activation and in regulation of the actin cytoskeleton...
