N Lamarche-Vane

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. ncbi CdGAP, a novel proline-rich GTPase-activating protein for Cdc42 and Rac
    N Lamarche-Vane
    Medical Research Council Laboratory for Molecular Cell Biology, CRC Oncogene and Signal Transduction Group, University College London, Gower Street, London WC1E 6BT, United Kingdom
    J Biol Chem 273:29172-7. 1998
  2. pmc Activation of the small GTPase Rac is sufficient to disrupt cadherin-dependent cell-cell adhesion in normal human keratinocytes
    V M Braga
    Medical Research Council Laboratory for Molecular Cell Biology and the Department of Biochemistry and Molecular Biology, University College London, London WC1E 6BT, United Kingdom
    Mol Biol Cell 11:3703-21. 2000
  3. ncbi Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA
    S K Prakash
    Departments of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Hum Mol Genet 9:477-88. 2000
  4. ncbi Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP
    N K Hussain
    Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, H3A 2B4, Canada
    Nat Cell Biol 3:927-32. 2001

Collaborators

  • A Hall
  • B K Kay
  • N K Hussain
  • S Jenna
  • S K Prakash
  • V M Braga
  • T P Stossel
  • S E Antonarakis
  • C C Quinn
  • S Wasiak
  • M Glogauer
  • P S McPherson
  • M Guipponi
  • H Y Zoghbi
  • M A Mancini
  • M Betson
  • B Xu
  • X Li
  • R Paylor
  • D L Armstrong

Detail Information

Publications4

  1. ncbi CdGAP, a novel proline-rich GTPase-activating protein for Cdc42 and Rac
    N Lamarche-Vane
    Medical Research Council Laboratory for Molecular Cell Biology, CRC Oncogene and Signal Transduction Group, University College London, Gower Street, London WC1E 6BT, United Kingdom
    J Biol Chem 273:29172-7. 1998
    ..Thus, CdGAP is a novel GAP that is likely to participate in Cdc42- and Rac-induced signaling pathways leading to actin reorganization...
  2. pmc Activation of the small GTPase Rac is sufficient to disrupt cadherin-dependent cell-cell adhesion in normal human keratinocytes
    V M Braga
    Medical Research Council Laboratory for Molecular Cell Biology and the Department of Biochemistry and Molecular Biology, University College London, London WC1E 6BT, United Kingdom
    Mol Biol Cell 11:3703-21. 2000
    ..Because Rac activity is also necessary for migration, Rac is a good candidate to coordinately regulate cell-cell and cell-substratum adhesion during tumorigenesis...
  3. ncbi Functional analysis of ARHGAP6, a novel GTPase-activating protein for RhoA
    S K Prakash
    Departments of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Hum Mol Genet 9:477-88. 2000
    ..These results suggest that ARHGAP6 has two independent functions: one as a GAP with specificity for RhoA and the other as a cytoskeletal protein that promotes actin remodeling...
  4. ncbi Endocytic protein intersectin-l regulates actin assembly via Cdc42 and N-WASP
    N K Hussain
    Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, Quebec, H3A 2B4, Canada
    Nat Cell Biol 3:927-32. 2001
    ..These studies reveal a role for intersectin-l in a novel mechanism of N-WASP activation and in regulation of the actin cytoskeleton...