- Assessing the genomic evidence for conserved transcribed pseudogenes under selectionAmit N Khachane
Department of Biology, McGill University, Stewart Biology Building, 1205 Docteur Penfield Ave, Montreal, QC, H3A 1B1 Canada
BMC Genomics 10:435. 2009..The most obvious indicators of such functional importance are significant evidence of conservation and selection pressure...
- Strong association between pseudogenization mechanisms and gene sequence lengthAmit N Khachane
Department of Biology, McGill University, Stewart Biology Building, Montreal, QC, H3A 1B1, Canada
Biol Direct 4:38. 2009..Protein-coding genes longer than 3000 bp are 6 times more likely to produce nonprocessed pseudogenes than processed ones...
- Mining mammalian transcript data for functional long non-coding RNAsAmit N Khachane
Department of Biology, McGill University, Montreal, Quebec, Canada
PLoS ONE 5:e10316. 2010..It is therefore essential to use bioinformatic approaches to identify the likely functional candidates in a high throughput manner...