R Joober

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. ncbi request reprint DRD3 and DAT1 genes in schizophrenia: an association study
    R Joober
    Douglas Hospital Research Centre, 6875 Boulevard LaSalle, H4H 1R3, Verdun, Canada
    J Psychiatr Res 34:285-91. 2000
  2. ncbi request reprint Lack of association between the hSKCa3 channel gene CAG polymorphism and schizophrenia
    R Joober
    Montreal General Hospital Research Institute, Department of Psychiatry, McGill University, Quebec, Canada
    Am J Med Genet 88:154-7. 1999
  3. pmc T102C polymorphism in the 5HT2A gene and schizophrenia: relation to phenotype and drug response variability
    R Joober
    Montreal General Hospital Research Institute, Douglas Hospital Research Centre, Verdun QC
    J Psychiatry Neurosci 24:141-6. 1999
  4. ncbi request reprint Association between the methylenetetrahydrofolate reductase 677C-->T missense mutation and schizophrenia
    R Joober
    Centre for Research in Neuroscience, Montreal General Hospital Research Institute, 1650 Cedar Avenue, Montreal H3G 1A4, Canada
    Mol Psychiatry 5:323-6. 2000
  5. ncbi request reprint Polyglutamine coding genes in bipolar disorder: lack of association with selected candidate loci
    G Turecki
    Centre for Research in Neuroscience, The Montreal General Hospital, McGill University, 1650 Cedar Ave, Montreal, Canada
    J Affect Disord 58:63-8. 2000
  6. ncbi request reprint MAOA: association and linkage studies with lithium responsive bipolar disorder
    G Turecki
    Centre for Research in Neuroscience, Montreal General Hospital, McGill University, Canada
    Psychiatr Genet 9:13-6. 1999
  7. ncbi request reprint Prediction of level of serotonin 2A receptor binding by serotonin receptor 2A genetic variation in postmortem brain samples from subjects who did or did not commit suicide
    G Turecki
    Centre for Research in Neuroscience, Montreal General Hospital, McGill University, Canada
    Am J Psychiatry 156:1456-8. 1999
  8. ncbi request reprint Lithium responsive bipolar disorder, unilineality, and chromosome 18: A linkage study
    G Turecki
    Centre for Research in Neuroscience, The Montreal General Hospital, McGill University, Montreal, Canada
    Am J Med Genet 88:411-5. 1999
  9. pmc Toward a model of cognitive insight in first-episode psychosis: verbal memory and hippocampal structure
    L Buchy
    Brain Imaging Group, Douglas Mental Health University Institute, Quebec, Canada
    Schizophr Bull 36:1040-9. 2010
  10. doi request reprint Early intervention in psychosis: specialized intervention and early case identification
    A Malla
    Douglas Mental Health University Institute, McGill University, Montreal, Quebec, Canada
    Encephale 36:S38-45. 2010

Collaborators

Detail Information

Publications19

  1. ncbi request reprint DRD3 and DAT1 genes in schizophrenia: an association study
    R Joober
    Douglas Hospital Research Centre, 6875 Boulevard LaSalle, H4H 1R3, Verdun, Canada
    J Psychiatr Res 34:285-91. 2000
    ..To investigate the role of the dopamine receptor 3 (DRD3) and transporter 1 (DAT1) genes in schizophrenia or in modulating its phenotype...
  2. ncbi request reprint Lack of association between the hSKCa3 channel gene CAG polymorphism and schizophrenia
    R Joober
    Montreal General Hospital Research Institute, Department of Psychiatry, McGill University, Quebec, Canada
    Am J Med Genet 88:154-7. 1999
    ..In addition, hSKCa3 was mapped to chromosome 1. Our results do not support the involvement of this particular CAG repeat-containing gene in schizophrenia...
  3. pmc T102C polymorphism in the 5HT2A gene and schizophrenia: relation to phenotype and drug response variability
    R Joober
    Montreal General Hospital Research Institute, Douglas Hospital Research Centre, Verdun QC
    J Psychiatry Neurosci 24:141-6. 1999
    ..These result suggest that the 5HT2A-receptor gene may play a role in a subset of schizophrenia characterized by poor long-term outcome and poor response to neuroleptics...
  4. ncbi request reprint Association between the methylenetetrahydrofolate reductase 677C-->T missense mutation and schizophrenia
    R Joober
    Centre for Research in Neuroscience, Montreal General Hospital Research Institute, 1650 Cedar Avenue, Montreal H3G 1A4, Canada
    Mol Psychiatry 5:323-6. 2000
    ....
  5. ncbi request reprint Polyglutamine coding genes in bipolar disorder: lack of association with selected candidate loci
    G Turecki
    Centre for Research in Neuroscience, The Montreal General Hospital, McGill University, 1650 Cedar Ave, Montreal, Canada
    J Affect Disord 58:63-8. 2000
    ..Results obtained with the repeat expansion detection technique (RED) have indicated that bipolar patients have an excess of expanded CAG repeats. However, it is not clear which loci account for this difference...
  6. ncbi request reprint MAOA: association and linkage studies with lithium responsive bipolar disorder
    G Turecki
    Centre for Research in Neuroscience, Montreal General Hospital, McGill University, Canada
    Psychiatr Genet 9:13-6. 1999
    ..The investigation used 138 patients and 108 normal controls. In addition, 25 families were also studied. Our results were not supportive of a major role of MAOA in the predisposition to bipolar disorder...
  7. ncbi request reprint Prediction of level of serotonin 2A receptor binding by serotonin receptor 2A genetic variation in postmortem brain samples from subjects who did or did not commit suicide
    G Turecki
    Centre for Research in Neuroscience, Montreal General Hospital, McGill University, Canada
    Am J Psychiatry 156:1456-8. 1999
    ..However, there remains some controversy regarding the biological specificity of these findings. The authors hypothesized that the variance observed in brain 5-HTR2A binding is genetically mediated, at least in part...
  8. ncbi request reprint Lithium responsive bipolar disorder, unilineality, and chromosome 18: A linkage study
    G Turecki
    Centre for Research in Neuroscience, The Montreal General Hospital, McGill University, Montreal, Canada
    Am J Med Genet 88:411-5. 1999
    ..In conclusion, our results are congruent with previous reports that suggest an advantage of unilineal pedigrees in linkage analysis of bipolar disorder and cannot rule out a parent-of-origin effect in this genomic region...
  9. pmc Toward a model of cognitive insight in first-episode psychosis: verbal memory and hippocampal structure
    L Buchy
    Brain Imaging Group, Douglas Mental Health University Institute, Quebec, Canada
    Schizophr Bull 36:1040-9. 2010
    ..The HC may be a viable location among others for the brain system that underlies aspects of cognitive insight in individuals with an FEP...
  10. doi request reprint Early intervention in psychosis: specialized intervention and early case identification
    A Malla
    Douglas Mental Health University Institute, McGill University, Montreal, Quebec, Canada
    Encephale 36:S38-45. 2010
    ....
  11. ncbi request reprint Lack of association between bipolar disorder and tyrosine hydroxylase: a meta-analysis
    G Turecki
    Department of Neurology and Neuroscience, Centre for Research in Neuroscience, McGill University, Montreal, Canada
    Am J Med Genet 74:348-52. 1997
    ..02 (0.68-1.54). Test of the null hypothesis that the mean log odds ratio equals zero (chi2 = 0.11; 5 df; P > 0.05) indicated that there was no overall association between bipolar disorder and tyrosine hydroxylase...
  12. ncbi request reprint Tourette syndrome and dopaminergic genes: a family-based association study in the French Canadian founder population
    A Díaz-Anzaldúa
    McGill University Health Centre, Montreal, Quebec, Canada
    Mol Psychiatry 9:272-7. 2004
    ..No associations were found for DRD2, DRD3 or SLC6A3. These data support the notion that DRD4 and MOA-A genes may confer an increased risk for developing TS in the French Canadian population...
  13. ncbi request reprint Association and linkage studies of CRH and PENK genes in bipolar disorder: a collaborative IGSLI study
    M Alda
    Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
    Am J Med Genet 96:178-81. 2000
    ..In conclusion, our study does not support the hypothesis that genes coding for CRH or PENK contribute to the genetic susceptibility to bipolar disorder. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 96:178-181, 2000...
  14. ncbi request reprint TPH and suicidal behavior: a study in suicide completers
    G Turecki
    Douglas Hospital Research Institute, Department of Psychiatry, McGill University, Verdun, Quebec, Canada
    Mol Psychiatry 6:98-102. 2001
    ..These and other results continue to point to the substantial role that the gene that codes for TPH may play in the neurobiology of suicidal behavior...
  15. doi request reprint Cortisol response to a psychosocial stressor in schizophrenia: blunted, delayed, or normal?
    K Brenner
    University of Montreal, Department of Psychology, 2900 Edouard Montpetit Blvd, Montreal, Quebec, Canada
    Psychoneuroendocrinology 34:859-68. 2009
    ..Our objective was to determine the extent to which cortisol reaction can discriminate between controls and schizophrenia patients while controlling for symptom severity, personality, body mass index (BMI) and smoking...
  16. doi request reprint Investigating cognitive deficits and symptomatology across pre-morbid adjustment patterns in first-episode psychosis
    L Bechard-Evans
    Department of Psychiatry, McGill University, Montreal, Quebec, Canada
    Psychol Med 40:749-59. 2010
    ..In addition, consistent heterogeneity within these impairments remains unexplained. One potential source of variability may be the level of pre-morbid adjustment prior to the onset of first-episode psychosis (FEP)...
  17. ncbi request reprint Drug induced weight gain, an impediment to successful pharmacotherapy: focus on antipsychotics
    T Baptista
    Department of Physiology, P O Box 93, Los Andes University Medical School, Merida, 5101 A, Venezuela
    Curr Drug Targets 5:279-99. 2004
    ..Notwithstanding this, novel strategies are necessary to treat this side effect in a clinical population particularly prone to poor compliance and under a high risk of negative drug interaction...
  18. ncbi request reprint Autism spectrum disorders associated with X chromosome markers in French-Canadian males
    J Gauthier
    Centre Hospitalier de l Universite de Montreal, Research Centre, Notre Dame Hospital, Montreal, QC, Canada
    Mol Psychiatry 11:206-13. 2006
    ..00001). These results provide support for the existence of a locus on the X chromosome that predisposes the FC to autism spectrum disorders...
  19. pmc LRRTM1 on chromosome 2p12 is a maternally suppressed gene that is associated paternally with handedness and schizophrenia
    C Francks
    Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
    Mol Psychiatry 12:1129-39, 1057. 2007
    ..LRRTM1 is a candidate gene for involvement in several common neurodevelopmental disorders, and may have played a role in human cognitive and behavioral evolution...