Research Topics
Genomes and GenesSpecies | Natalie GrizenkoSummaryAffiliation: McGill University Country: Canada Publications
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Detail Information
Publications
Is the inattentive subtype of ADHD different from the combined/hyperactive subtype?Natalie Grizenko
McGill University
J Atten Disord 13:649-57. 2010..To compare the ADHD combined/hyperactive subtype (ADHD/CH) to the ADHD inattentive subtype (ADHD/I) on the level of comorbidity, treatment response, and possible etiological factors...
Relationship between response to methylphenidate treatment in children with ADHD and psychopathology in their familiesNatalie Grizenko
McGill University and Douglas Hospital, Montreal, Quebec, Canada
J Am Acad Child Adolesc Psychiatry 45:47-53. 2006..To compare the pattern of familial aggregation of psychopathology in children who are good responders (GR) to methylphenidate (MPH) versus those who are poor responders (PR)...
Efficacy of methylphenidate in children with attention-deficit hyperactivity disorder and learning disabilities: a randomized crossover trialNatalie Grizenko
Department of Psychiatry, McGill University and Division of Child and Adolescent Psychiatry, Douglas Hospital, Montreal, Que
J Psychiatry Neurosci 31:46-51. 2006..To determine whether children with attention-deficit hyperactivity disorder (ADHD) and learning disabilities respond differently to methylphenidate (MPH) compared with children with ADHD only...- Relation of maternal stress during pregnancy to symptom severity and response to treatment in children with ADHDNatalie Grizenko
Department of Psychiatry, McGill University, Montreal, Canada
J Psychiatry Neurosci 33:10-6. 2008..A second objective was to examine whether there is an association between maternal stress and children's response to methylphenidate (MPH)... - COMT Val108/158Met polymorphism and the modulation of task-oriented behavior in children with ADHDSarojini Sengupta
Department of Human Genetics, McGill University, Montreal, QC, Canada
Neuropsychopharmacology 33:3069-77. 2008..However, no genotype by treatment interaction was observed. These results suggest that the COMT Val(108/158)Met polymorphism modulates task-oriented behavior, but it does not modulate the response of this behavior with MPH treatment... - Factor structure of the restricted academic situation scale: implications for ADHDSherif Karama
Department of Psychiatry, McGill University, Douglas Hospital Research Centre, Montreal, Canada
J Atten Disord 12:442-8. 2009..25 mg/kg of methylphenidate. Placebo and methylphenidate were each administered according to a double-blind placebo-controlled crossover design... - Dopamine transporter 3'-UTR VNTR genotype and ADHD: a pharmaco-behavioural genetic study with methylphenidateRidha Joober
Department of Psychiatry, McGill University and Douglas Hospital Research Centre, Montreal, QC, Canada
Neuropsychopharmacology 32:1370-6. 2007..They also suggest the presence of genetic heterogeneity that could be indexed by the quality of behavioral response to MPH... - The 5-HTTLPR polymorphism of the serotonin transporter gene and short term behavioral response to methylphenidate in children with ADHDGeeta A Thakur
Integrated Program in Neuroscience, McGill University, 3801 University Street, Montreal, H3A 2B4, Canada
BMC Psychiatry 10:50. 2010..In this study, we have investigated the relationship between the 5-HTTLPR polymorphism in the serotonin transporter gene (SLC6A4) and the response of ADHD relevant behaviors with methylphenidate treatment... - Dopamine transporter 3'UTR VNTR genotype is a marker of performance on executive function tasks in children with ADHDSherif Karama
Department of Psychiatry, McGill University, Montreal, Canada
BMC Psychiatry 8:45. 2008..Executive function deficits are considered among the most important pathogenic pathways leading to ADHD and may index part of the heterogeneity in this disorder... - Performance on the continuous performance test in children with ADHD is associated with sleep efficiencyReut Gruber
Douglas Mental Health University Institute and McGill University, Montreal, Canada
Sleep 30:1003-9. 2007..To examine whether the level of sleep efficiency of children diagnosed with ADHD moderates their performance on the Continuous Performance Test (CPT) while receiving a placebo and while receiving methylphenidate (MPH)... - Relation between therapeutic response and side effects induced by methylphenidate as observed by parents and teachers of children with ADHDJames Lee
Department of Psychiatry, McGill University, Montreal, Canada
BMC Psychiatry 11:70. 2011..The desired (therapeutic) and undesired (side) effects of methylphenidate might have underlying correlations. The aim of this study was to explore the strength and the possible sources of these correlations... - Family-based association study of ADHD and genes increasing the risk for smoking behavioursGeeta A Thakur
Douglas Mental Health University Institute, 6875 LaSalle Blvd, Montreal, Quebec, Canada
Arch Dis Child 97:1027-33. 2012.... - Clinical response to methylphenidate in children diagnosed with attention-deficit hyperactivity disorder and comorbid psychiatric disordersMariam Ter-Stepanian
Department of Educational and Counselling Psychology, McGill University, Montreal, Quebec
Can J Psychiatry 55:305-12. 2010..To determine to what extent the clinical response to methylphenidate (MPH) is affected by psychiatric comorbidities in children diagnosed with attention-deficit hyperactivity disorder (ADHD)... - Dopamine transporter genotype and stimulant side effect factors in youth diagnosed with attention-deficit/hyperactivity disorderReut Gruber
Douglas Mental Health University Institute, Department of Psychiatry, McGill University, Montreal, Canada
J Child Adolesc Psychopharmacol 19:233-9. 2009..Preliminary evidence suggests that pharmacogenetic analysis using DAT1 variants shows promise for identifying individuals at increased or decreased risk for poor tolerability... - LPHN3 and attention-deficit/hyperactivity disorder: interaction with maternal stress during pregnancyZia Choudhry
Douglas Mental Health University Institute, McGill University, Verdun, QC, Canada
J Child Psychol Psychiatry 53:892-902. 2012..Recently, a significant association was reported between ADHD and LPHN3 (which codes for latrophilin 3), and replicated in independent samples... - Actigraphic monitoring during sleep of children with ADHD on methylphenidate and placeboGeorge Schwartz
Douglas Hospital Research Centre and the Department of Psychiatry, McGill University, Montreal, Canada
J Am Acad Child Adolesc Psychiatry 43:1276-82. 2004..This suggests that responders to MPH treatment do not experience greater sleep disturbances than nonresponders, at least at the dose studied... - COMT Val108/158Met gene variant, birth weight, and conduct disorder in children with ADHDSarojini M Sengupta
Department of Human Genetics, McGill University, and Douglas Hospital Research Centre, Montreal, Quebec, Canada
J Am Acad Child Adolesc Psychiatry 45:1363-9. 2006..We have attempted to replicate these findings in a group of ADHD children using a similar research design... - Physical activity experiences of boys with and without ADHDWilliam J Harvey
Department of Kinesiology and Physical Education, McGill University, Montreal, Quebec, Canada
Adapt Phys Activ Q 26:131-50. 2009..Task-specific interventions and a wider range of mixed methods research are recommended for future research studies in ADHD... - Body weight and ADHD: examining the role of self-regulationZia Choudhry
Department of Human Genetics, McGill University, Montreal, Canada
PLoS ONE 8:e55351. 2013..The objective of this study is to investigate the relation between body weight/BMI and cognitive, emotional and motor characteristics in children with ADHD... - Fundamental movement skills and children with attention-deficit hyperactivity disorder: peer comparisons and stimulant effectsWilliam J Harvey
Department of Kinesiology and Physical Education, McGill University, 475 Pine Avenue West, Montreal, QC, Canada
J Abnorm Child Psychol 35:871-82. 2007..It is concluded that children with ADHD may be at risk for developmental delays in movement skill performance. Potential factors underlying the movement skill difficulties are discussed, with suggestions for future research... - Catechol-O-methyltransferase (COMT) Val108/158 Met polymorphism does not modulate executive function in children with ADHDEvan Taerk
Department of Psychiatry, McGill University and Douglas Hospital Research Centre, Montreal, Quebec, H4H 1R3, Canada
BMC Med Genet 5:30. 2004.... - Maternal smoking during pregnancy and ADHD: a comprehensive clinical and neurocognitive characterizationGeeta A Thakur
Integrated Program in Neuroscience, McGill University, Montreal, Canada
Nicotine Tob Res 15:149-57. 2013..The objective of this study is to test the hypothesis that children with ADHD exposed to MSDP show a distinctive clinical and neurocognitive profile when compared with unexposed children... - Comprehensive phenotype/genotype analyses of the norepinephrine transporter gene (SLC6A2) in ADHD: relation to maternal smoking during pregnancyGeeta A Thakur
Integrated Program in Neuroscience, McGill University, Montreal, Quebec, Canada
PLoS ONE 7:e49616. 2012..We tested the association between 30 tag SNPs within the SLC6A2 gene and ADHD, with stratification based on maternal smoking during pregnancy, an environmental factor strongly associated with ADHD... - Effectiveness of a therapeutic summer camp for children with ADHD: Phase I Clinical Intervention TrialJulie Hantson
McGill University, Montreal, Quebec, Canada
J Atten Disord 16:610-7. 2012..This was an open-label, nonrandomized Phase I Clinical Intervention Trial... - Maternal Stress during Pregnancy, ADHD Symptomatology in Children and Genotype: Gene-Environment InteractionNatalie Grizenko
Department of Psychiatry, McGill University, Montreal, Quebec
J Can Acad Child Adolesc Psychiatry 21:9-15. 2012..Our objective was to control for these factors by using an intra-familial design, and investigate gene-environment interactions... - Efficacy of Methylphenidate in ADHD Children across the Normal and the Gifted Intellectual SpectrumNatalie Grizenko
Department of Psychiatry, McGill University, Montreal, Canada Douglas Mental Health University Institute, Montreal
J Can Acad Child Adolesc Psychiatry 21:282-8. 2012....