Research Topics
Species | Yukiori GotoSummaryAffiliation: McGill University Country: Canada Publications
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Detail Information
Publications
The Yin and Yang of dopamine release: a new perspectiveYukiori Goto
Department of Psychiatry, McGill University, Research and Training Building, 1033 Pine Avenue West, Montreal, Quebec H3A 1A1, Canada
Neuropharmacology 53:583-7. 2007....
Is schizophrenia developmental adaptation to environmental menaces?Yukiori Goto
Department of Psychiatry, McGill University, Montreal, QC, Canada
Med Hypotheses 77:756-62. 2011....
Dopamine modulation of hippocampal-prefrontal cortical interaction drives memory-guided behaviorYukiori Goto
Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
Cereb Cortex 18:1407-14. 2008..These results provide a unique perspective on the mechanism of memory-based goal-directed behavior...
Limbic and cortical information processing in the nucleus accumbensYukiori Goto
Department of Psychiatry, McGill University, Montreal, Quebec, H3A 1A1, Canada
Trends Neurosci 31:552-8. 2008....
Functional and dysfunctional synaptic plasticity in prefrontal cortex: roles in psychiatric disordersYukiori Goto
Department of Psychiatry, McGill University, Montreal, Quebec H3A 1A1, Canada
Biol Psychiatry 67:199-207. 2010....
Dopamine-dependent interactions between limbic and prefrontal cortical plasticity in the nucleus accumbens: disruption by cocaine sensitizationYukiori Goto
Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
Neuron 47:255-66. 2005..Thus, interactions of limbic-prefrontal cortical synaptic plasticity and its dysfunction within the accumbens could underlie complex information processing deficits observed in individuals following psychostimulant administration...
Chronic stress modulation of prefrontal cortical NMDA receptor expression disrupts limbic structure-prefrontal cortex interactionYoung A Lee
Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, QC, Canada H3A 1A1
Eur J Neurosci 34:426-36. 2011..These results suggest that chronic stress disrupts NMDA receptor-dependent limbic structure-PFC information processing...
Neurodevelopmental disruption of cortico-striatal function caused by degeneration of habenula neuronsYoung A Lee
Department of Psychiatry, McGill University, Montreal, Quebec, Canada
PLoS ONE 6:e19450. 2011..Given that the monoamine systems are highly vulnerable to neurodevelopmental insults, damages in the habenula during early neurodevelopment may cause devastating effects on the wide-spread brain areas targeted by monoamine innervations...
Alterations in medial prefrontal cortical activity and plasticity in rats with disruption of cortical developmentYukiori Goto
Department of Neuroscience, University of Pittsburgh, Pennsylvania 15260, USA
Biol Psychiatry 60:1259-67. 2006..Thus, a genetic predisposition can lead to developmental compromises that may leave the system more susceptible to deficits induced by subsequent environmental variables such as stress...
The dopamine system and the pathophysiology of schizophrenia: a basic science perspectiveYukiori Goto
Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
Int Rev Neurobiol 78:41-68. 2007....
Regulation of firing of dopaminergic neurons and control of goal-directed behaviorsAnthony A Grace
Departments of Neuroscience, Psychiatry and Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
Trends Neurosci 30:220-7. 2007....
Dopaminergic modulation of limbic and cortical drive of nucleus accumbens in goal-directed behaviorYukiori Goto
Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
Nat Neurosci 8:805-12. 2005..These results suggest that the dynamics of DA release regulate the balance between limbic and cortical drive through activation and inactivation of DA receptor subtypes in the accumbens, and this regulates goal-directed behavior...
COMT Val108/158Met polymorphism and the modulation of task-oriented behavior in children with ADHDSarojini Sengupta
Department of Human Genetics, McGill University, Montreal, QC, Canada
Neuropsychopharmacology 33:3069-77. 2008..However, no genotype by treatment interaction was observed. These results suggest that the COMT Val(108/158)Met polymorphism modulates task-oriented behavior, but it does not modulate the response of this behavior with MPH treatment...
Prefrontal lesion reverses abnormal mesoaccumbens response in an animal model of schizophreniaYukiori Goto
Center for Neuropharmacology and Neuroscience, Albany Medical College, Albany, New York 12208, USA
Biol Psychiatry 55:172-6. 2004..CONCLUSIONS: This result suggests that abnormal behaviors in these animals might be related to excessive prefrontal drive of accumbens neurons upon dopamine activation...
Altered prefrontal cortex-nucleus accumbens information processing in a developmental animal model of schizophreniaYukiori Goto
Center for Neuropharmacology and Neuroscience, Albany Medical College, Albany, New York 12208, USA
Ann N Y Acad Sci 1003:398-401. 2003
Delayed mesolimbic system alteration in a developmental animal model of schizophreniaYukiori Goto
Center for Neuropharmacology and Neuroscience, Albany Medical College, Albany, New York 12208, USA
J Neurosci 22:9070-7. 2002....
Timing-dependent limbic-motor synaptic integration in the nucleus accumbensYukiori Goto
Center for Neuropharmacology and Neuroscience, Albany Medical College, Albany, NY 12208, USA
Proc Natl Acad Sci U S A 99:13189-93. 2002..These mechanisms allow for both coincidence detection and input selection in this integrative brain region...
