Yukiori Goto

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. pmc The Yin and Yang of dopamine release: a new perspective
    Yukiori Goto
    Department of Psychiatry, McGill University, Research and Training Building, 1033 Pine Avenue West, Montreal, Quebec H3A 1A1, Canada
    Neuropharmacology 53:583-7. 2007
  2. pmc Neurodevelopmental disruption of cortico-striatal function caused by degeneration of habenula neurons
    Young A Lee
    Department of Psychiatry, McGill University, Montreal, Quebec, Canada
    PLoS ONE 6:e19450. 2011
  3. doi Is schizophrenia developmental adaptation to environmental menaces?
    Yukiori Goto
    Department of Psychiatry, McGill University, Montreal, QC, Canada
    Med Hypotheses 77:756-62. 2011
  4. doi Functional and dysfunctional synaptic plasticity in prefrontal cortex: roles in psychiatric disorders
    Yukiori Goto
    Department of Psychiatry, McGill University, Montreal, Quebec H3A 1A1, Canada
    Biol Psychiatry 67:199-207. 2010
  5. pmc Limbic and cortical information processing in the nucleus accumbens
    Yukiori Goto
    Department of Psychiatry, McGill University, Montreal, Quebec, H3A 1A1, Canada
    Trends Neurosci 31:552-8. 2008
  6. pmc Dopamine modulation of hippocampal-prefrontal cortical interaction drives memory-guided behavior
    Yukiori Goto
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Cereb Cortex 18:1407-14. 2008
  7. ncbi Dopamine-dependent interactions between limbic and prefrontal cortical plasticity in the nucleus accumbens: disruption by cocaine sensitization
    Yukiori Goto
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Neuron 47:255-66. 2005
  8. doi Chronic stress modulation of prefrontal cortical NMDA receptor expression disrupts limbic structure-prefrontal cortex interaction
    Young A Lee
    Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, QC, Canada H3A 1A1
    Eur J Neurosci 34:426-36. 2011
  9. ncbi Regulation of firing of dopaminergic neurons and control of goal-directed behaviors
    Anthony A Grace
    Departments of Neuroscience, Psychiatry and Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Trends Neurosci 30:220-7. 2007
  10. ncbi The dopamine system and the pathophysiology of schizophrenia: a basic science perspective
    Yukiori Goto
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Int Rev Neurobiol 78:41-68. 2007

Detail Information

Publications17

  1. pmc The Yin and Yang of dopamine release: a new perspective
    Yukiori Goto
    Department of Psychiatry, McGill University, Research and Training Building, 1033 Pine Avenue West, Montreal, Quebec H3A 1A1, Canada
    Neuropharmacology 53:583-7. 2007
    ....
  2. pmc Neurodevelopmental disruption of cortico-striatal function caused by degeneration of habenula neurons
    Young A Lee
    Department of Psychiatry, McGill University, Montreal, Quebec, Canada
    PLoS ONE 6:e19450. 2011
    ..Given that the monoamine systems are highly vulnerable to neurodevelopmental insults, damages in the habenula during early neurodevelopment may cause devastating effects on the wide-spread brain areas targeted by monoamine innervations...
  3. doi Is schizophrenia developmental adaptation to environmental menaces?
    Yukiori Goto
    Department of Psychiatry, McGill University, Montreal, QC, Canada
    Med Hypotheses 77:756-62. 2011
    ....
  4. doi Functional and dysfunctional synaptic plasticity in prefrontal cortex: roles in psychiatric disorders
    Yukiori Goto
    Department of Psychiatry, McGill University, Montreal, Quebec H3A 1A1, Canada
    Biol Psychiatry 67:199-207. 2010
    ....
  5. pmc Limbic and cortical information processing in the nucleus accumbens
    Yukiori Goto
    Department of Psychiatry, McGill University, Montreal, Quebec, H3A 1A1, Canada
    Trends Neurosci 31:552-8. 2008
    ....
  6. pmc Dopamine modulation of hippocampal-prefrontal cortical interaction drives memory-guided behavior
    Yukiori Goto
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Cereb Cortex 18:1407-14. 2008
    ..These results provide a unique perspective on the mechanism of memory-based goal-directed behavior...
  7. ncbi Dopamine-dependent interactions between limbic and prefrontal cortical plasticity in the nucleus accumbens: disruption by cocaine sensitization
    Yukiori Goto
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Neuron 47:255-66. 2005
    ..Thus, interactions of limbic-prefrontal cortical synaptic plasticity and its dysfunction within the accumbens could underlie complex information processing deficits observed in individuals following psychostimulant administration...
  8. doi Chronic stress modulation of prefrontal cortical NMDA receptor expression disrupts limbic structure-prefrontal cortex interaction
    Young A Lee
    Department of Psychiatry, McGill University, 1033 Pine Avenue West, Montreal, QC, Canada H3A 1A1
    Eur J Neurosci 34:426-36. 2011
    ..These results suggest that chronic stress disrupts NMDA receptor-dependent limbic structure-PFC information processing...
  9. ncbi Regulation of firing of dopaminergic neurons and control of goal-directed behaviors
    Anthony A Grace
    Departments of Neuroscience, Psychiatry and Psychology, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Trends Neurosci 30:220-7. 2007
    ....
  10. ncbi The dopamine system and the pathophysiology of schizophrenia: a basic science perspective
    Yukiori Goto
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Int Rev Neurobiol 78:41-68. 2007
    ....
  11. ncbi Alterations in medial prefrontal cortical activity and plasticity in rats with disruption of cortical development
    Yukiori Goto
    Department of Neuroscience, University of Pittsburgh, Pennsylvania 15260, USA
    Biol Psychiatry 60:1259-67. 2006
    ..Thus, a genetic predisposition can lead to developmental compromises that may leave the system more susceptible to deficits induced by subsequent environmental variables such as stress...
  12. ncbi Dopaminergic modulation of limbic and cortical drive of nucleus accumbens in goal-directed behavior
    Yukiori Goto
    Department of Neuroscience, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA
    Nat Neurosci 8:805-12. 2005
    ..These results suggest that the dynamics of DA release regulate the balance between limbic and cortical drive through activation and inactivation of DA receptor subtypes in the accumbens, and this regulates goal-directed behavior...
  13. pmc COMT Val108/158Met polymorphism and the modulation of task-oriented behavior in children with ADHD
    Sarojini Sengupta
    Department of Human Genetics, McGill University, Montreal, QC, Canada
    Neuropsychopharmacology 33:3069-77. 2008
    ..However, no genotype by treatment interaction was observed. These results suggest that the COMT Val(108/158)Met polymorphism modulates task-oriented behavior, but it does not modulate the response of this behavior with MPH treatment...
  14. ncbi Prefrontal lesion reverses abnormal mesoaccumbens response in an animal model of schizophrenia
    Yukiori Goto
    Center for Neuropharmacology and Neuroscience, Albany Medical College, Albany, New York 12208, USA
    Biol Psychiatry 55:172-6. 2004
    ..Because a prefrontal cortical lesion eliminates postpubertal abnormal behaviors in these animals, we investigated whether altered accumbens responses were reversed with this manipulation...
  15. ncbi Altered prefrontal cortex-nucleus accumbens information processing in a developmental animal model of schizophrenia
    Yukiori Goto
    Center for Neuropharmacology and Neuroscience, Albany Medical College, Albany, New York 12208, USA
    Ann N Y Acad Sci 1003:398-401. 2003
  16. ncbi Delayed mesolimbic system alteration in a developmental animal model of schizophrenia
    Yukiori Goto
    Center for Neuropharmacology and Neuroscience, Albany Medical College, Albany, New York 12208, USA
    J Neurosci 22:9070-7. 2002
    ....
  17. pmc Timing-dependent limbic-motor synaptic integration in the nucleus accumbens
    Yukiori Goto
    Center for Neuropharmacology and Neuroscience, Albany Medical College, Albany, NY 12208, USA
    Proc Natl Acad Sci U S A 99:13189-93. 2002
    ..These mechanisms allow for both coincidence detection and input selection in this integrative brain region...