E L Franco

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. ncbi request reprint Role and limitations of epidemiology in establishing a causal association
    Eduardo L Franco
    Department of Epidemiology, McGill University, 546 Pine Avenue West, Montreal, QC, Canada H2W1S6
    Semin Cancer Biol 14:413-26. 2004
  2. pmc Ano-genital human papillomavirus type 97 infection is detected in Canadian men but not women at risk or infected with the human immunodeficiency virus
    Marie Ève Landry
    Departement de Pathologie, Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada
    Virol J 9:243. 2012
  3. pmc Factors associated with cervical cancer screening uptake among Inuit women in Nunavik, Quebec, Canada
    Helen Cerigo
    Centre for Clinical Epidemiology, Jewish General Hospital, Montreal, Canada
    BMC Public Health 13:438. 2013
  4. doi request reprint Cervical human papillomavirus detection is not affected by menstrual phase
    Joseph E Tota
    Division of Cancer Epidemiology, McGill University, 546 Pine Avenue, West Montreal, QC, Canada H2W 1S6
    Sex Transm Infect 89:202-6. 2013
  5. doi request reprint Human papillomavirus and cancer prevention: gaps in knowledge and prospects for research, policy, and advocacy
    Eduardo L Franco
    Division of Cancer Epidemiology, McGill University, Montreal, Canada
    Vaccine 30:F175-82. 2012
  6. pmc Human papillomavirus testing with Pap triage for cervical cancer prevention in Canada: a cost-effectiveness analysis
    Shalini L Kulasingam
    Duke University, Center for Clinical Health Policy Research, Durham, NC, USA
    BMC Med 7:69. 2009
  7. pmc Human papillomavirus (HPV) types 16, 18, 31, 45 DNA loads and HPV-16 integration in persistent and transient infections in young women
    Agnihotram V Ramanakumar
    Division of Cancer Epidemiology, McGill University, Montreal, Quebec, Canada
    BMC Infect Dis 10:326. 2010
  8. pmc Use of latent class models to accommodate inter-laboratory variation in assessing genetic polymorphisms associated with disease risk
    Stephen D Walter
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    BMC Genet 9:51. 2008
  9. pmc Validation of dot blot hybridization and denaturing high performance liquid chromatography as reliable methods for TP53 codon 72 genotyping in molecular epidemiologic studies
    Tatiana Rabachini
    Ludwig Institute for Cancer Research, Sao Paulo, Brazil
    BMC Genet 11:44. 2010
  10. pmc Interaction between polymorphisms of the human leukocyte antigen and HPV-16 variants on the risk of invasive cervical cancer
    Patricia S de Araujo Souza
    Ludwig Institute for Cancer Research, Sao Paulo, Brazil
    BMC Cancer 8:246. 2008

Research Grants

  1. MOLECULAR EPIDEMIOLOGY OF PERSISTENT HPV INFECTION
    Eduardo Franco; Fiscal Year: 2001
  2. MOLECULAR EPIDEMIOLOGY OF PERSISTENT HPV INFECTION
    Eduardo Franco; Fiscal Year: 2003
  3. HITCH: A Study of HPV Transmission in Young Couples
    Eduardo L Franco; Fiscal Year: 2010

Collaborators

Detail Information

Publications106 found, 100 shown here

  1. ncbi request reprint Role and limitations of epidemiology in establishing a causal association
    Eduardo L Franco
    Department of Epidemiology, McGill University, 546 Pine Avenue West, Montreal, QC, Canada H2W1S6
    Semin Cancer Biol 14:413-26. 2004
    ..Both examples serve as paradigms of successful cooperation between epidemiologists and laboratory scientists in the pursuit of the understanding of cancer etiology...
  2. pmc Ano-genital human papillomavirus type 97 infection is detected in Canadian men but not women at risk or infected with the human immunodeficiency virus
    Marie Ève Landry
    Departement de Pathologie, Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada
    Virol J 9:243. 2012
    ..The prevalence of human papillomavirus type 97 (HPV97) was assessed in cervicovaginal cells from women living in Canada and in anal samples from HIV-seropositive men living in Toronto...
  3. pmc Factors associated with cervical cancer screening uptake among Inuit women in Nunavik, Quebec, Canada
    Helen Cerigo
    Centre for Clinical Epidemiology, Jewish General Hospital, Montreal, Canada
    BMC Public Health 13:438. 2013
    ..The objectives of this study were to determine Pap smear utilization rates and to determine factors associated with time-inappropriate use of cervical cancer screening among a cohort of Inuit women from Nunavik, Quebec, Canada...
  4. doi request reprint Cervical human papillomavirus detection is not affected by menstrual phase
    Joseph E Tota
    Division of Cancer Epidemiology, McGill University, 546 Pine Avenue, West Montreal, QC, Canada H2W 1S6
    Sex Transm Infect 89:202-6. 2013
    ..We evaluated the effects of OC use and timing of cervical sampling in relation to women's last menstrual period (LMP) on HPV detection, and viral load in the Brazilian Ludwig-McGill cohort study...
  5. doi request reprint Human papillomavirus and cancer prevention: gaps in knowledge and prospects for research, policy, and advocacy
    Eduardo L Franco
    Division of Cancer Epidemiology, McGill University, Montreal, Canada
    Vaccine 30:F175-82. 2012
    ..This article forms part of a special supplement entitled "Comprehensive Control of HPV Infections and Related Diseases" Vaccine Volume 30, Supplement 5, 2012...
  6. pmc Human papillomavirus testing with Pap triage for cervical cancer prevention in Canada: a cost-effectiveness analysis
    Shalini L Kulasingam
    Duke University, Center for Clinical Health Policy Research, Durham, NC, USA
    BMC Med 7:69. 2009
    ..We determined the potential cost-effectiveness of including human papillomavirus tests for cervical cancer screening for Canada and three provinces: Alberta, Newfoundland and Ontario...
  7. pmc Human papillomavirus (HPV) types 16, 18, 31, 45 DNA loads and HPV-16 integration in persistent and transient infections in young women
    Agnihotram V Ramanakumar
    Division of Cancer Epidemiology, McGill University, Montreal, Quebec, Canada
    BMC Infect Dis 10:326. 2010
    ..HPV burden is a predictor for high-grade cervical intraepithelial neoplasia and cancer. The natural history of HPV load in young women being recently exposed to HPV is described in this paper...
  8. pmc Use of latent class models to accommodate inter-laboratory variation in assessing genetic polymorphisms associated with disease risk
    Stephen D Walter
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    BMC Genet 9:51. 2008
    ..Possible LCMs are characterised in terms of the number of laboratory measurements available, and if their error rates are assumed to be differential or non-differential by disease status and/or laboratory...
  9. pmc Validation of dot blot hybridization and denaturing high performance liquid chromatography as reliable methods for TP53 codon 72 genotyping in molecular epidemiologic studies
    Tatiana Rabachini
    Ludwig Institute for Cancer Research, Sao Paulo, Brazil
    BMC Genet 11:44. 2010
    ..The most widely accepted method of detecting genotyping error is to confirm genotypes by sequencing and/or via a separate method...
  10. pmc Interaction between polymorphisms of the human leukocyte antigen and HPV-16 variants on the risk of invasive cervical cancer
    Patricia S de Araujo Souza
    Ludwig Institute for Cancer Research, Sao Paulo, Brazil
    BMC Cancer 8:246. 2008
    ..HLA class II polymorphisms are also associated with genetic susceptibility to ICC. Our aim is to verify if these associations are influenced by HPV-16 variability...
  11. pmc A randomized controlled trial of Human Papillomavirus (HPV) testing for cervical cancer screening: trial design and preliminary results (HPV FOCAL Trial)
    Gina S Ogilvie
    Department of Family Practice, University of British Columbia, Vancouver, Canada
    BMC Cancer 10:111. 2010
    ....
  12. doi request reprint Integrating human papillomavirus vaccination in cervical cancer control programmes
    Eduardo L Franco
    Department of Oncology, McGill University, Montreal, Que, H2W 1S6 Canada
    Public Health Genomics 12:352-61. 2009
    ..Combining modern screening techniques and universal prophylactic HPV vaccination is likely to produce the most advanced and cost-effective preventive strategy to fight cervical cancer worldwide...
  13. ncbi request reprint Cervical cancer screening following the implementation of prophylactic human papillomavirus vaccination
    Eduardo L Franco
    Division of Cancer Epidemiology, Departments of Oncology and Epidemiology, McGill University, 546 Pine Avenue West, Montreal, QC, Canada
    Future Oncol 3:319-27. 2007
    ..This strategy has the added benefit of providing immunosurveillance of vaccinated populations...
  14. ncbi request reprint A new window into the natural history of human papillomavirus infection: a view from the ALTS (Atypical Squamous Cells of Undetermined Significance/Low-Grade Squamous Intraepithelial Lesions Triage Study) trial
    Eduardo L Franco
    Division of Cancer Epidemiology, McGill University, Montreal, QC, Canada
    J Infect Dis 195:1560-2. 2007
  15. ncbi request reprint Evidence-based policy recommendations on cancer screening and prevention
    Eduardo L Franco
    Department of Oncology, McGill University, 546 Pine Avenue W, Montreal, Que, Canada, H2W 1S6
    Cancer Detect Prev 26:350-61. 2002
    ....
  16. ncbi request reprint Chapter 29: Knowledge gaps and priorities for research on prevention of HPV infection and cervical cancer
    Eduardo L Franco
    Division of Cancer Epidemiology, Departments of Oncology and Epidemiology and Biostatistics, McGill University, 546 Pine Avenue West, Montreal, Quebec, Canada
    Vaccine 24:S3/242-9. 2006
    ..The field of HPV and cervical cancer prevention has never been so multi-disciplinary. A new era has begun and the challenges are many...
  17. ncbi request reprint Chapter 20: Issues in planning cervical cancer screening in the era of HPV vaccination
    Eduardo L Franco
    Division of Cancer Epidemiology, Department of Oncology, McGill University, 546 Pine Avenue West, Montreal, Quebec, Canada
    Vaccine 24:S3/171-7. 2006
    ....
  18. pmc Epidemiology as a tool to reveal inequalities in breast cancer care
    Eduardo L Franco
    Division of Cancer Epidemiology, McGill University, Montreal, Canada
    PLoS Med 3:e48. 2006
  19. ncbi request reprint Vaccination against human papillomavirus infection: a new paradigm in cervical cancer control
    Eduardo L Franco
    Division of Cancer Epidemiology, Department of Oncology and Epidemiology, McGill University, 546 Pine Avenue West, Montreal, Que, Canada H2W 1S6
    Vaccine 23:2388-94. 2005
    ..It will take many years before we can rationally develop cervical cancer screening strategies that will be cost-effective for the proper surveillance of women protected by HPV vaccination...
  20. pmc Commentary: Health inequity could increase in poor countries if universal HPV vaccination is not adopted
    Eduardo L Franco
    Departments of Oncology and Epidemiology, McGill University, Montreal, QC, Canada H2W 1S6
    BMJ 335:378-9. 2007
  21. doi request reprint Ovarian cancer and oral contraceptives
    Eduardo L Franco
    Department of Oncology and Epidemiology, McGill University, Montreal, Quebec, Canada H2W1S6
    Lancet 371:277-8. 2008
  22. doi request reprint Commentary: Smoking and human papillomavirus infection: the pursuit of credibility for an epidemiologic association
    E L Franco
    Department of Epidemiology and Biostatistics and Department of Oncology, McGill University, Montreal, Canada
    Int J Epidemiol 37:547-8. 2008
  23. ncbi request reprint Cervical cancer screening following prophylactic human papillomavirus vaccination
    Eduardo L Franco
    Division of Cancer Epidemiology, Department of Oncology, McGill University, Montreal, Canada
    Vaccine 26:A16-23. 2008
    ..This strategy has the added benefit of providing epidemiological surveillance of vaccinated populations...
  24. pmc Radiodiagnostic imaging in pregnancy and the risk of childhood malignancy: raising the bar
    Eduardo L Franco
    Division of Cancer Epidemiology, McGill University, Montreal, Canada
    PLoS Med 7:e1000338. 2010
    ..Eduardo Franco and Guy-Anne Turgeon discuss new findings from Joel Ray and colleagues on the cancer risk following prenatal exposure to radiodiagnostic imaging, and where new research needs to be focused...
  25. pmc Invited commentary: Human papillomavirus infection and risk of cervical precancer--using the right methods to answer the right questions
    Eduardo L Franco
    Division of Cancer Epidemiology, McGill University, 546 Pine Avenue West, Montreal, Quebec, Canada
    Am J Epidemiol 171:164-8. 2010
    ..In this commentary, the authors extend the findings of Castle et al. by providing additional empirical evidence in support of their arguments...
  26. doi request reprint Integration of human papillomavirus vaccination and cervical cancer screening in Latin America and the Caribbean
    Eduardo L Franco
    Division of Cancer Epidemiology, McGill University, Montreal, QC, Canada
    Vaccine 26:L88-95. 2008
    ..This approach would serve as the central component of a system that plays the dual role of providing screening and surveillance as integrated and complementary activities sharing centralized resources and coordination...
  27. doi request reprint Persistence of an incident human papillomavirus infection and timing of cervical lesions in previously unexposed young women
    Helen Trottier
    Division of Cancer Epidemiology, McGill University, 546 Pine Avenue West, Montreal, Quebec, Canada H2W1S6
    Cancer Epidemiol Biomarkers Prev 18:854-62. 2009
    ....
  28. doi request reprint The expected impact of HPV vaccination on the accuracy of cervical cancer screening: the need for a paradigm change
    Eduardo L Franco
    Department of Oncology, McGill University, Canada
    Arch Med Res 40:478-85. 2009
    ..HPV followed by Pap strategy can also serve a secondary role in post-vaccination surveillance...
  29. ncbi request reprint Persistent human papillomavirus infection as a predictor of cervical intraepithelial neoplasia
    N F Schlecht
    Department of Oncology, McGill University, 546 Pine Ave W, Montreal, Quebec, Canada H2W1S6
    JAMA 286:3106-14. 2001
    ....
  30. ncbi request reprint The epidemiology of cervical cancer
    Eduardo L Franco
    Department of Epidemiology and Oncology, McGill University, Montreal, QC, Canada
    Cancer J 9:348-59. 2003
    ..This is the first instance in which a necessary cause has been demonstrated in cancer epidemiology--a realization that has obvious implications for primary and secondary prevention of this neoplastic disease...
  31. ncbi request reprint Prospects for controlling cervical cancer at the turn of the century
    Eduardo L Franco
    Department of Oncology, Department of Epidemiology and Biostatistics, McGill University, 546 Pine Avenue West, Montreal, QC, Canada H2W 1S6
    Salud Publica Mex 45:S367-75. 2003
    ..This paper is available too at: http://www.insp.mx/salud/index.html...
  32. ncbi request reprint Are we ready for a paradigm change in cervical cancer screening?
    Eduardo L Franco
    Department of Epidemiology, McGill University, Montreal, H2W1S6, Quebec, Canada
    Lancet 362:1866-7. 2003
  33. ncbi request reprint Male circumcision and AIDS in Africa: Primum non nocere versus the collective good
    Eduardo L Franco
    Division of Cancer Epidemiology, McGill University, 546 Pine Avenue West, Montreal, QC, Canada H2W1S6
    Epidemiology 15:133-4. 2004
  34. pmc Cervical cancer: epidemiology, prevention and the role of human papillomavirus infection
    E L Franco
    Department of Oncology, McGill University, Montreal, Que
    CMAJ 164:1017-25. 2001
    ..These are fundamental stepping stones for the implementation of effective public health programs aimed at the control of cervical cancer...
  35. ncbi request reprint Epidemiology of acquisition and clearance of cervical human papillomavirus infection in women from a high-risk area for cervical cancer
    E L Franco
    Department of Oncology, McGill University, Montreal, QC, Canada H2W 1S6
    J Infect Dis 180:1415-23. 1999
    ..Although a woman's age did not affect mean duration for oncogenic types (13-14 months), nononcogenic-type infections lasted longer (10. 2 months) among younger (<35 years old) than in older women (5.6 months)...
  36. ncbi request reprint Cervical coinfection with human papillomavirus (HPV) types as a predictor of acquisition and persistence of HPV infection
    M C Rousseau
    Department of Oncology, McGill University, Montreal, Canada
    J Infect Dis 184:1508-17. 2001
    ..Given the increasing prominence of HPV vaccination as a potential preventive approach, it is imperative that additional insights on cross-type protection be obtained from longer-term longitudinal investigations...
  37. doi request reprint Type-specific duration of human papillomavirus infection: implications for human papillomavirus screening and vaccination
    Helen Trottier
    Division of Cancer Epidemiology, McGill University, Montreal, Canada
    J Infect Dis 197:1436-47. 2008
    ..We studied genotype-specific infection duration among 2462 women enrolled in the Ludwig-McGill cohort study...
  38. doi request reprint Determinants of human papillomavirus infection among Inuit women of northern Quebec, Canada
    Lauren Kay Hamlin-Douglas
    Departments of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, QC
    Sex Transm Dis 37:377-81. 2010
    ..Findings suggest that for older women, markers of recent sexual activity are more predictive of HR-HPV status than markers of lifetime sexual history...
  39. doi request reprint Human papillomavirus infection and reinfection in adult women: the role of sexual activity and natural immunity
    Helen Trottier
    Division of Cancer Epidemiology, McGill University, Department of Social and Preventive Medicine and Ste Justine Hospital, University of Montreal, Montreal, Canada
    Cancer Res 70:8569-77. 2010
    ..HPV infection and reinfection were strongly associated with sexual activity. This study suggests that natural immunity does not play a role in controlling the extent of reinfections...
  40. doi request reprint Assessment of the performance of algorithms for cervical cancer screening: evidence from the Ludwig-McGill cohort study
    M Chevarie-Davis
    McGill University, Montreal, Canada
    Gynecol Oncol 128:415-9. 2013
    ..We performed long term risk stratification based on screening test results and compared the accuracy of different tests and their combinations...
  41. ncbi request reprint Repeatability of sexual history in longitudinal studies on HPV infection and cervical neoplasia: determinants of reporting error at follow-up interviews
    N F Schlecht
    Department of Epidemiology, McGill University, Montreal, Canada
    J Epidemiol Biostat 6:393-407. 2001
    ..CONCLUSIONS: Information on sexual behaviours is not reliably collected in epidemiological studies of sexually transmitted diseases, which may influence the magnitude of relative risk estimates...
  42. ncbi request reprint Viral load as a predictor of the risk of cervical intraepithelial neoplasia
    Nicolas F Schlecht
    Division of Cancer Epidemiology, McGill University, 546 Pine Avenue West, Montreal, Quebec, Canada H2W 1S6
    Int J Cancer 103:519-24. 2003
    ..6 (95% CI 0.5-13.2). Viral burden appears to have an independent effect on SIL incidence. Measurement of viral load, as a surrogate for HPV persistence, may identify women at risk of developing cervical cancer precursors...
  43. ncbi request reprint Randomized controlled trial of human papillomavirus testing versus Pap cytology in the primary screening for cervical cancer precursors: design, methods and preliminary accrual results of the Canadian cervical cancer screening trial (CCCaST)
    Marie Helene Mayrand
    Division of Cancer Epidemiology, Department of Oncology, McGill University, and Département de Microbiologie Infectiologie, Hôpital Notre Dame du Centre Hospitalier Universitaire de l Université de Montréal, QC, Canada
    Int J Cancer 119:615-23. 2006
    ..Because of its design, CCCaST will provide sound evidence for formulating cervical cancer screening strategies...
  44. ncbi request reprint Human papillomavirus infections with multiple types and risk of cervical neoplasia
    Helen Trottier
    Division of Cancer Epidemiology, Sir Mortimer B Davis Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    Cancer Epidemiol Biomarkers Prev 15:1274-80. 2006
    ..We studied the association between multiple HPV types and cervical lesions among 2,462 Brazilian women participating in the Ludwig-McGill study group investigation of the natural history of HPVs and cervical neoplasia...
  45. ncbi request reprint Human papillomavirus DNA versus Papanicolaou screening tests for cervical cancer
    Marie Helene Mayrand
    Department of Oncology and Epidemiology and Biostatistics, McGill University, Montreal, Canada
    N Engl J Med 357:1579-88. 2007
    ..To determine whether testing for DNA of oncogenic human papillomaviruses (HPV) is superior to the Papanicolaou (Pap) test for cervical-cancer screening, we conducted a randomized trial comparing the two methods...
  46. ncbi request reprint Prophylactic human papillomavirus vaccines: potential for sea change
    Alex Ferenczy
    McGill University and the Sir Mortimer B Davis Jewish General Hospital, Montreal, Quebec, Canada
    Expert Rev Vaccines 6:511-25. 2007
    ....
  47. ncbi request reprint Modeling the time dependence of the association between human papillomavirus infection and cervical cancer precursor lesions
    Nicolas F Schlecht
    Department of Oncology, Faculty of Medicine, McGill University, Montreal, Quebec, Canada
    Am J Epidemiol 158:878-86. 2003
    ..The waning in hazard ratios should be considered in the implementation of HPV testing-based screening programs...
  48. doi request reprint Use of nonsteroidal anti-inflammatory drugs and prostate cancer risk: a meta-analysis
    Salaheddin M Mahmud
    Department of Oncology, McGill University, Montreal, Quebec, Canada
    Int J Cancer 127:1680-91. 2010
    ..There is a need for well-designed observational studies with adequate exposure measurements, accurate case definition, attention to latency effects, and careful adjustment for screening and other biases...
  49. ncbi request reprint The natural history of type-specific human papillomavirus infections in female university students
    Harriet Richardson
    Departments of Oncology, McGill University, Montreal, Quebec, H2W 1S6 Canada
    Cancer Epidemiol Biomarkers Prev 12:485-90. 2003
    ..Whereas the majority of episodes with a type-specific HPV infection cleared within 2 years, there were many women who were either reinfected with a new HPV genotype or presumably experienced reactivation of their initial infection...
  50. ncbi request reprint Predictors of cervical coinfection with multiple human papillomavirus types
    Marie Claude Rousseau
    Department of Oncology, McGill University, Montreal, Quebec, H2W 4507 010 1S6 Canada
    Cancer Epidemiol Biomarkers Prev 12:1029-37. 2003
    ..Our results suggest that the risk factor profile for HPV coinfection among HPV-infected women shares several similarities with risk factors for any HPV infection...
  51. ncbi request reprint HLA polymorphisms and cervical human Papillomavirus infection in a cohort of Montreal University students
    Salaheddin M Mahmud
    Division of Cancer Epidemiology, McGill University, Montreal, Quebec, Canada
    J Infect Dis 196:82-90. 2007
    ..HLA polymorphisms have been linked to the risk of cervical cancer, but very little is known about the role that they play in the acquisition and persistence of HPV infection...
  52. doi request reprint Brief research report: uncertainty-inducing and reassuring facts about HPV: a descriptive study of French Canadian women
    Natalie O Rosen
    Department of Psychology, McGill University, Montreal, Quebec, B3A 1B1, Canada
    Health Care Women Int 30:892-902. 2009
    ..The authors outline what specific facts about HPV health providers can emphasize to alleviate anxiety and encourage women to feel reassured of their low cancer risk following a negative test result...
  53. ncbi request reprint High-risk human papillomavirus infection of the genital tract of women with a previous history or current high-grade vulvar intraepithelial neoplasia
    Frederic Goffin
    Département d Obstétrique, Pathologie et Microbiologie Infectiologie, Hôpital Notre Dame Centre Hospitalier de l Université de Montréal, CHUM, Montreal, Quebec, Canada
    J Med Virol 78:814-9. 2006
    ..2). Multifocal vulvar HPV infection was detected in women with previous or active VIN-3. Longitudinal studies are required to determine if the multifocality of HPV infection on the vulva could explain the high recurrence rate of VIN-3...
  54. ncbi request reprint Modifiable risk factors associated with clearance of type-specific cervical human papillomavirus infections in a cohort of university students
    Harriet Richardson
    Department of Oncology, McGill University, 546 Pine Avenue West, Montreal, Quebec, Canada H2W 1S6
    Cancer Epidemiol Biomarkers Prev 14:1149-56. 2005
    ....
  55. ncbi request reprint Chapter 6: Epidemiology and transmission dynamics of genital HPV infection
    Ann N Burchell
    Division of Cancer Epidemiology, Departments of Oncology and Epidemiology and Biostatistics, McGill University, 546 Pine Avenue West, Montreal, Quebec, Canada
    Vaccine 24:S3/52-61. 2006
    ..Although the duration of infectivity may be short, current evidence suggests that HPV is highly transmissible. The implications of transmission dynamics for the success of future HPV vaccines are discussed...
  56. ncbi request reprint Modeling the sexual transmissibility of human papillomavirus infection using stochastic computer simulation and empirical data from a cohort study of young women in Montreal, Canada
    Ann N Burchell
    Department of Oncology, Faculty of Medicine, McGill University, 546 Pine Avenue West, Montreal, Quebec, Canada H2W 1S6
    Am J Epidemiol 163:534-43. 2006
    ..With high transmissibility, any potential protective effect of condoms would disappear over multiple intercourse acts, underlining the need for an effective HPV vaccine...
  57. doi request reprint The impact of intolerance of uncertainty on anxiety after receiving an informational intervention about HPV: a randomised controlled study
    Natalie O Rosen
    Department of Psychology, McGill University, Montreal, QC, Canada H3A 1B1
    Psychol Health 25:651-68. 2010
    ..Women with higher IU are more likely to seek HPV information, but they may also be at risk for experiencing higher anxiety because factual uncertainties about HPV cannot be resolved through the provision of more information...
  58. ncbi request reprint The p53 codon 72 polymorphism and risk of high-grade cervical intraepithelial neoplasia
    Anita Koushik
    Department of Epidemiology and Biostatistics, Division of Cancer Epidemiology, McGill University, 546 Pine Avenue West, Montreal, Que, Canada H2W1S6
    Cancer Detect Prev 29:307-16. 2005
    ..However, research on this topic has been contentious, which prompted us to carry out a case-control study in the Montreal area...
  59. doi request reprint Prevalence, clearance, and incidence of anal human papillomavirus infection in HIV-infected men: the HIPVIRG cohort study
    Alexandra de Pokomandy
    Departement De Microbiologie et Infectiologie, Hôpital Notre Dame du Centre Hospitalier de l Université de Montréal, département de médecine familiale, Faculte de Medecine, Universite de Montreal, Montreal, Quebec, Canada
    J Infect Dis 199:965-73. 2009
    ..This study was conducted to better understand the natural history of type-specific HPV infection in the anus...
  60. ncbi request reprint Human papillomavirus infection and time to progression and regression of cervical intraepithelial neoplasia
    Nicolas F Schlecht
    Department of Oncology and Epidemiology, McGill University, Montreal, Quebec, Canada
    J Natl Cancer Inst 95:1336-43. 2003
    ..We estimated rates of progression and regression and sojourn times of cervical squamous intraepithelial lesions (SILs) according to HPV status...
  61. ncbi request reprint Non-steroidal anti-inflammatory drug use and prostate cancer in a high-risk population
    Salaheddin M Mahmud
    Department of Oncology, McGill University, Montreal, Canada
    Eur J Cancer Prev 15:158-64. 2006
    ..Further observational studies with adequate case definition and exposure measurements and careful adjustment for detection bias are warranted...
  62. doi request reprint Prevalence and age distribution of human papillomavirus infection in a population of Inuit women in Nunavik, Quebec
    Lauren Kay Hamlin-Douglas
    Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Canada
    Cancer Epidemiol Biomarkers Prev 17:3141-9. 2008
    ..Our aim was to study the prevalence and age distribution of human papillomavirus (HPV) infection among Inuit women in Nunavik, northern Quebec, a population at high risk of cervical cancer...
  63. doi request reprint Promising strategies for cervical cancer screening in the post-human papillomavirus vaccination era
    Joseph Tota
    Department of Oncology, McGill University, Montreal, QC H2W 1S6, Canada
    Sex Health 7:376-82. 2010
    ....
  64. ncbi request reprint Evaluation of a convenient enzyme immunoassay to assess the quality of genital specimens submitted for the detection of human papillomavirus DNA by consensus PCR
    Joséphine Aho
    Departement de Microbiologie et Immunologie, Universite de Montreal, Que, Montreal, Canada
    J Clin Virol 29:127-33. 2004
    ..Although the PGMY-line blot assay detected 50 cells per test, the beta-globin DIG-MWP test generated a signal above the detection cut-off with five cells per test...
  65. doi request reprint Human papillomavirus infections among couples in new sexual relationships
    Ann N Burchell
    Division of Cancer Epidemiology, McGill University, Montreal, QC, Canada
    Epidemiology 21:31-7. 2010
    ..Our objective was to describe the distribution of HPV infections among recently formed couples, using the partnership as the unit of analysis...
  66. pmc Management of low-grade cervical lesions in young women
    Susie Lau
    Department of Epidemiology and Biostatistics, McGill University, Montreal, Que
    CMAJ 173:771-4. 2005
  67. ncbi request reprint Effect of type of alcoholic beverage on the risks of upper aerodigestive tract cancers in Brazil
    N F Schlecht
    Department of Oncology, McGill University, Montreal, QC, Canada
    Cancer Causes Control 12:579-87. 2001
    ..CONCLUSION: Although methods of measurement can influence the interpretation of the carcinogenic nature of alcohols, increased RRs persisted with continued exposure for all types...
  68. ncbi request reprint Determinants of AIDS preventive behaviour among dental professionals
    J C Soto
    Department of Community Health, Hopital Saint Luc, Montreal, Quebec, Laval
    Can J Public Health 84:128-31. 1993
    ..Professionals who recap needles are three times more likely to sustain needlesticks than those who do not. Our results suggest the need to increase AIDS knowledge and to improve compliance to infection control measures among dentists...
  69. doi request reprint Detection and typing of human papillomavirus nucleic acids in biological fluids
    Francois Coutlee
    Departement de Microbiologie et Immunologie, Universite de Montreal, Montreal, Que, H2L 4M1 Canada
    Public Health Genomics 12:308-18. 2009
    ..Although assays have been developed for the evaluation of viral load, viral integration and HPV polymorphism in molecular epidemiological studies, their role in clinical practice is not currently defined...
  70. doi request reprint Determinants of delays in treatment initiation in children and adolescents diagnosed with leukemia or lymphoma in Canada
    Tam Dang-Tan
    Department of Oncology, McGill University, Montreal, Canada H2W1S6
    Int J Cancer 126:1936-43. 2010
    ..Factors related to the patients, their disease and the HCS may exert different influences on varying segments of the care pathway of leukemia and lymphoma patients...
  71. doi request reprint Effectiveness of cervical cancer screening at different ages
    Joseph Tota
    Department of Epidemiology, McGill University, 546 Pine Avenue West, Montreal, QC H2W1S6, Canada
    Womens Health (Lond Engl) 5:613-6. 2009
    ..Along with the information from this study, policymakers should consider the harms of screening at different ages as well as the absolute rate of cervical cancer in screened and unscreened women of different ages...
  72. pmc Use of the normalized absorbance ratio as an internal standardization approach to minimize measurement error in enzyme-linked immunosorbent assays for diagnosis of human papillomavirus infection
    Agnihotram V Ramanakumar
    Division of Cancer Epidemiology, McGill University, Montreal, QC, Canada
    J Clin Microbiol 48:791-6. 2010
    ..The NAR standardization is a simple procedure to reduce measurement error in seroepidemiological studies of HPV infection...
  73. ncbi request reprint Diversity of cutaneous human papillomavirus types in individuals with and without skin lesion
    Laila Alotaibi
    Laboratoire de Virologie Moleculaire, Centre de Recherche, Departement De Microbiologie et Infectiologie, et Medecine, Centre Hospitalier de l Universite de Montreal, Montreal, Que, Canada H2L 4M1
    J Clin Virol 36:133-40. 2006
    ..Human papillomavirus (HPV) is ubiquitous on the skin of normal and immunosuppressed hosts...
  74. ncbi request reprint Human papillomavirus infection and oral cancer: a case-control study in Montreal, Canada
    Javier Pintos
    Division of Cancer Epidemiology, McGill University, Montreal, Canada
    Oral Oncol 44:242-50. 2008
    ..16 (95%CI: 0.8-13.0), respectively. These results provide evidence supporting a strong causal association between HPV infection and tonsil-related cancers. The evidence for an etiologic link is less clear for non-tonsillar oral cancers...
  75. ncbi request reprint The epidemiology of genital human papillomavirus infection
    Helen Trottier
    Department of Oncology, McGill University, Montreal, Canada
    Vaccine 24:S1-15. 2006
    ..This shift in research focus coincides with a shift in cancer prevention techniques towards immunization with HPV vaccines and HPV testing of precancerous lesions...
  76. ncbi request reprint Polio vaccines, Simian Virus 40, and human cancer: the epidemiologic evidence for a causal association
    Tam Dang-Tan
    Department of Oncology, McGill University, Montreal, Canada
    Oncogene 23:6535-40. 2004
    ..A new generation of molecular epidemiologic studies is necessary to properly address these issues...
  77. pmc Sex-specific determinants of HIV infection among injection drug users in Montreal
    J Bruneau
    Department of Family Medicine, Centre Hospitalier de l Universite de Montreal, Montreal, Que
    CMAJ 164:767-73. 2001
    ..The objective of this study was to examine sex-specific behaviours associated with HIV infection among injection drug users in Montreal...
  78. doi request reprint Polymorphism of the capsid L1 gene of human papillomavirus types 31, 33, and 35
    Gilbert Cornut
    Centre de Recherche and Département de Microbiologie Infectiologie, Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada
    J Med Virol 82:1168-78. 2010
    ..dN/dS ratios were below 1.0 in extra-loop and intra-loop regions, but they were lower in extra-loop regions. These results suggest that sequences within and outside the hypervariable loops of L1 were under selective constraint...
  79. doi request reprint Are endometrial polyps true cancer precursors?
    Tamar Perri
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Jewish General Hospital, Montreal, Quebec, Canada
    Am J Obstet Gynecol 203:232.e1-6. 2010
    ..The purpose of this study was to assess whether endometrial polyps (EMPs) represent cancer precursors...
  80. ncbi request reprint Insulin-like growth factor-I and risk of high-grade cervical intraepithelial neoplasia
    Andrea Schaffer
    Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada
    Cancer Epidemiol Biomarkers Prev 16:716-22. 2007
    ..In contrast to the previously reported study, our results suggest that levels of IGF-I in young women may be inversely associated with HGCIN, a precursor to cervical cancer...
  81. doi request reprint Selected class I and class II HLA alleles and haplotypes and risk of high-grade cervical intraepithelial neoplasia
    Steven Ades
    Department of Epidemiology and Biostatistics, McGill University, Montreal, Canada
    Int J Cancer 122:2820-6. 2008
    ....
  82. ncbi request reprint Are self-collected samples comparable to physician-collected cervical specimens for human papillomavirus DNA testing? A systematic review and meta-analysis
    Patrick Petignat
    Senology and Gynaecologic Oncology Unit, Geneva University Hospitals, 1211 Geneva 14, Switzerland
    Gynecol Oncol 105:530-5. 2007
    ..To compare the detection rate of genital human papillomavirus (HPV) infection in self- and physician-obtained samples...
  83. ncbi request reprint Toward a reduction of the global burden of cervical cancer
    Thomas E Rohan
    Department of Epidemiology and Social Medicine, Albert Einstein College of Medicine, Yeshiva University, Bronx, NY 10461, USA
    Am J Obstet Gynecol 189:S37-9. 2003
    ....
  84. ncbi request reprint Sustained efficacy up to 4.5 years of a bivalent L1 virus-like particle vaccine against human papillomavirus types 16 and 18: follow-up from a randomised control trial
    Diane M Harper
    Department of Obstetrics and Gynecology, Norris Cotton Cancer Center, Dartmouth Medical School, Rubin 880, One Medical Center Drive, Lebanon, NH 03756, USA
    Lancet 367:1247-55. 2006
    ....
  85. ncbi request reprint Visual inspection as a cervical cancer screening method in a primary health care setting in Africa
    Ghislain Sangwa-Lugoma
    Department of Obstetrics and Gynecology, University of Kinshasa, Kinshasa, Democratic Republic of Congo
    Int J Cancer 119:1389-95. 2006
    ..Given their lower cost and easy deployment, visual inspection methods merit further assessment as cervical cancer screening methods for low-resource countries...
  86. ncbi request reprint Advances in prevention of cervical cancer and other human papillomavirus-related diseases
    Ian H Frazer
    University of Queensland, Center for Immunology and Cancer Research, Brisbane, QLD 4072, Australia
    Pediatr Infect Dis J 25:S65-81, quiz S82. 2006
  87. ncbi request reprint Randomized controlled trials of HPV testing and Pap cytology: toward evidence-based cervical cancer prevention
    Eduardo L Franco
    Int J Cancer 110:1-2. 2004
  88. ncbi request reprint Human papillomavirus and cervical dysplasia in Nunavut: prelude to a screening strategy
    Sylvia M Healey
    Health Protection Unit, Department of Health, Government of Nunavut, Iqaluit, Nunavut, Canada
    Int J Circumpolar Health 63:199-201. 2004
    ..To determine the prevalence of oncogenic human papillomavirus' (HPV) in Nunavut and to assess the association between HPV and squamous intraepithelial lesions (SIL) as a prelude to planning a better screening strategy...
  89. ncbi request reprint Report of the 2003 pan-Canadian forum on cervical cancer prevention and control
    Gavin Stuart
    Faculty of Medicine, University of British Columbia, Vancouver BC
    J Obstet Gynaecol Can 26:1004-28. 2004
    ..To develop evidence-based consensus recommendations on the delivery of cervical cancer screening, human papillomavirus (HPV) education, HPV testing, and the optimal tool for cervical cytology within the Canadian health system...
  90. ncbi request reprint Efficacy of a bivalent L1 virus-like particle vaccine in prevention of infection with human papillomavirus types 16 and 18 in young women: a randomised controlled trial
    Diane M Harper
    Department of Obstetrics and Gynecology, Norris Cotton Cancer Center, Dartmouth Medical School, Hanover, NH, USA
    Lancet 364:1757-65. 2004
    ....
  91. ncbi request reprint Prognostic significance of lymph node variables and human papillomavirus DNA in invasive vulvar carcinoma
    Alvaro P Pinto
    Department of Pathology, Hospital de Clinicas, Universidade Federal do Parana, Curitiba, PR, Brazil
    Gynecol Oncol 92:856-65. 2004
    ..The present study investigates the influence of lymph node pathological features and HPV DNA status on the prognosis of vulvar invasive tumors...
  92. ncbi request reprint Human papillomavirus type 33 polymorphisms and high-grade squamous intraepithelial lesions of the uterine cervix
    Soraya Khouadri
    Laboratoire de Virologie Moléculaire du Centre de Recherche, Hôpital Notre Dame du Centre Hospitalier de l Université de Montréal, Montreal Quebec, Canada
    J Infect Dis 194:886-94. 2006
    ..We investigated the association between polymorphisms of human papillomavirus (HPV)-33 and squamous intraepithelial lesions (SILs)...
  93. ncbi request reprint Multiparameter calibration of a natural history model of cervical cancer
    Jane J Kim
    Program in Health Decision Science, Department of Health Policy and Management, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 166:137-50. 2007
    ..The authors found that leveraging primary data from longitudinal studies provides unique opportunities for model parameterization of the unobservable nature of HPV infection and its role in the development of cervical cancer...
  94. ncbi request reprint Past, present, and future of HPV research: highlights from the 19th International Papillomavirus Conference-HPV2001
    Luisa Lina Villa
    Virology Department, Ludwig Institute for Cancer Research, R Professor Antonio Prudente 109, 4th Floor, 01509 010 Sao Paulo, Brazil
    Virus Res 89:163-73. 2002
    ..Highlights derive from the analysis of more than 500 papers presented at the Conference...
  95. doi request reprint Reassessing the epidemiology of human papillomavirus infection: back to basics
    Eduardo L Franco
    Sex Transm Dis 35:283-5. 2008
  96. ncbi request reprint Innovations in understanding the biology of cervical cancer
    Judith K Wolf
    Department of Gynecologic Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 98:2064-9. 2003
    ..Identification of molecular changes in cervical cancer and knowledge about the importance of HPV infection in cervical cancer can lead to new therapies to treat existing cervical cancer and, in the long term, prevent the disease...
  97. ncbi request reprint Viral load of episomal and integrated forms of human papillomavirus type 33 in high-grade squamous intraepithelial lesions of the uterine cervix
    Soraya Khouadri
    Laboratoire de Virologie Moléculaire du Centre de Recherche, Centre Hospitalier de l Universite de Montreal, Universite de Montreal, Quebec, Canada
    Int J Cancer 121:2674-81. 2007
    ..0004] was associated with the presence of HPV-33 integration. High episomal loads in HSIL and the presence of integration in women without SIL are likely to weaken the usefulness of HPV load of integrated forms in clinical practice...
  98. pmc Reproductive health of adolescent girls perinatally infected with HIV
    Susan B Brogly
    Center for Biostatistics in AIDS Research, Harvard School of Public Health, Boston, Mass 02115 6017, USA
    Am J Public Health 97:1047-52. 2007
    ..We sought to describe the reproductive health of adolescent girls perinatally infected with HIV...
  99. ncbi request reprint Lack of agreement between cervicography and cytology and the effect of human papillomavirus infection and viral load
    Nicolas F Schlecht
    Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY, USA
    J Low Genit Tract Dis 10:229-37. 2006
    ..Cohort studies of the natural history of human papillomavirus (HPV) infection and cervical squamous intraepithelial lesions with repeated screening allow the comparison of different macroscopic and microscopic diagnostic methods...
  100. ncbi request reprint Polymorphisms of the human leukocyte antigen DRB1 and DQB1 genes and the natural history of human papillomavirus infection
    Paulo C Maciag
    Department of Biochemistry, University of Sao Paulo, and Ludwig Institute for Cancer Research, Sao Paulo, Brazil
    J Infect Dis 186:164-72. 2002
    ..The results suggest that HLA class II polymorphisms are involved in clearance and maintenance of HPV infection...
  101. ncbi request reprint Newly-isolated HPV97, related to HPV18 and 45 is frequently detected in HIV-positive men from the Montreal area
    Isabelle Gorska-Flipot
    Int J Cancer 122:1195-7. 2008

Research Grants8

  1. MOLECULAR EPIDEMIOLOGY OF PERSISTENT HPV INFECTION
    Eduardo Franco; Fiscal Year: 2001
    ....
  2. MOLECULAR EPIDEMIOLOGY OF PERSISTENT HPV INFECTION
    Eduardo Franco; Fiscal Year: 2003
    ..abstract_text> ..
  3. HITCH: A Study of HPV Transmission in Young Couples
    Eduardo L Franco; Fiscal Year: 2010
    ....