Pierre Ernst

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. pmc Pramipexole use and the risk of pneumonia
    Pierre Ernst
    Center for Clinical Epidemiology, Lady Davis Research Institute Jewish General Hospital, 3755 Cote Ste Catherine, Montreal, QC, H3T 1E2, Canada
    BMC Neurol 12:113. 2012
  2. doi request reprint Systemic effects of inhaled corticosteroids
    Pierre Ernst
    Centre for Clinical Epidemiology, Lady Davis Research Institute, Jewish General Hospital, 3755 Cote Ste Catherine, Montreal, Quebec, Canada
    Curr Opin Pulm Med 18:85-9. 2012
  3. pmc Risk of herpes zoster in patients prescribed inhaled corticosteroids: a cohort study
    Pierre Ernst
    Center for Clinical Epidemiology, Lady Davis Research Institute, Jewish General Hospital, Montreal, Canada
    BMC Pulm Med 11:59. 2011
  4. ncbi request reprint Predictors of a more favourable response to combined therapy with salmeterol and fluticasone as initial maintenance therapy in asthma
    Pierre Ernst
    Division of Clinical Epidemiology, McGill University Health Center, Royal Victoria Hospital R4 29, 687 Pine Avenue West, Montreal, Quebec, Canada
    Respir Med 102:77-81. 2008
  5. ncbi request reprint Inhaled corticosteroid use in chronic obstructive pulmonary disease and the risk of hospitalization for pneumonia
    Pierre Ernst
    Pharmacoepidemiology Research Unit, Department of Medicine, McGill University Health Centre, and Division of Clinical Epidemiology, Ross 4 29, Royal Victoria Hospital, 687 Pine Avenue West, Montreal, PQ, Quebec, H3A 1A1 Canada
    Am J Respir Crit Care Med 176:162-6. 2007
  6. doi request reprint Effectiveness of combination therapies in asthma: an observational study
    Samy Suissa
    McGill Pharmacoepidemiology Research Unit, McGill University Health Centre, Montreal, Canada
    Pulm Pharmacol Ther 22:194-8. 2009
  7. ncbi request reprint Underreporting exacerbation of chronic obstructive pulmonary disease in a longitudinal cohort
    Lisa Langsetmo
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, 3650 St Urbain, Montreal, PQ, Canada
    Am J Respir Crit Care Med 177:396-401. 2008
  8. doi request reprint Inhaled corticosteroids and the risks of diabetes onset and progression
    Samy Suissa
    Lady Davis Research Institute, Jewish General Hospital, Montreal, Quebec, Canada
    Am J Med 123:1001-6. 2010
  9. doi request reprint Risk of glaucoma in elderly patients treated with inhaled corticosteroids for chronic airflow obstruction
    Anne V Gonzalez
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University Health Centre, Canada
    Pulm Pharmacol Ther 23:65-70. 2010
  10. ncbi request reprint Safety and effectiveness of long-acting inhaled beta-agonist bronchodilators when taken with inhaled corticosteroids
    Pierre Ernst
    McGill University, Montreal, Quebec, Canada
    Ann Intern Med 145:692-4. 2006

Detail Information

Publications69

  1. pmc Pramipexole use and the risk of pneumonia
    Pierre Ernst
    Center for Clinical Epidemiology, Lady Davis Research Institute Jewish General Hospital, 3755 Cote Ste Catherine, Montreal, QC, H3T 1E2, Canada
    BMC Neurol 12:113. 2012
    ..It is uncertain whether pramipexole or other dopamine agonists increase the risk of pneumonia...
  2. doi request reprint Systemic effects of inhaled corticosteroids
    Pierre Ernst
    Centre for Clinical Epidemiology, Lady Davis Research Institute, Jewish General Hospital, 3755 Cote Ste Catherine, Montreal, Quebec, Canada
    Curr Opin Pulm Med 18:85-9. 2012
    ..We review the articles appearing in the last year which have addressed the safety of ICSs when used in the treatment of asthma and chronic obstructive pulmonary disease (COPD)...
  3. pmc Risk of herpes zoster in patients prescribed inhaled corticosteroids: a cohort study
    Pierre Ernst
    Center for Clinical Epidemiology, Lady Davis Research Institute, Jewish General Hospital, Montreal, Canada
    BMC Pulm Med 11:59. 2011
    ..We hypothesised that inhaled corticosteroids (ICS) are a risk factor for herpes zoster especially among users of inhibitors of cytochrome P450 enzymes involved in their metabolism...
  4. ncbi request reprint Predictors of a more favourable response to combined therapy with salmeterol and fluticasone as initial maintenance therapy in asthma
    Pierre Ernst
    Division of Clinical Epidemiology, McGill University Health Center, Royal Victoria Hospital R4 29, 687 Pine Avenue West, Montreal, Quebec, Canada
    Respir Med 102:77-81. 2008
    ..We wished to identify clinical characteristics of patients which would enable one to identify a sub-group of patients who would benefit most from initiating sustained controller therapy with combination therapy...
  5. ncbi request reprint Inhaled corticosteroid use in chronic obstructive pulmonary disease and the risk of hospitalization for pneumonia
    Pierre Ernst
    Pharmacoepidemiology Research Unit, Department of Medicine, McGill University Health Centre, and Division of Clinical Epidemiology, Ross 4 29, Royal Victoria Hospital, 687 Pine Avenue West, Montreal, PQ, Quebec, H3A 1A1 Canada
    Am J Respir Crit Care Med 176:162-6. 2007
    ..Inhaled corticosteroids are commonly prescribed to patients with chronic obstructive pulmonary disease (COPD)...
  6. doi request reprint Effectiveness of combination therapies in asthma: an observational study
    Samy Suissa
    McGill Pharmacoepidemiology Research Unit, McGill University Health Centre, Montreal, Canada
    Pulm Pharmacol Ther 22:194-8. 2009
    ..We compared the effectiveness in a real world setting of two such combinations available in a single inhaler...
  7. ncbi request reprint Underreporting exacerbation of chronic obstructive pulmonary disease in a longitudinal cohort
    Lisa Langsetmo
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, 3650 St Urbain, Montreal, PQ, Canada
    Am J Respir Crit Care Med 177:396-401. 2008
    ..Unreported exacerbations and failure to seek medical attention may have consequences on the health of patients with chronic obstructive pulmonary disease...
  8. doi request reprint Inhaled corticosteroids and the risks of diabetes onset and progression
    Samy Suissa
    Lady Davis Research Institute, Jewish General Hospital, Montreal, Quebec, Canada
    Am J Med 123:1001-6. 2010
    ..We assessed whether the use and dose of inhaled corticosteroids increase the risk of diabetes onset and progression...
  9. doi request reprint Risk of glaucoma in elderly patients treated with inhaled corticosteroids for chronic airflow obstruction
    Anne V Gonzalez
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University Health Centre, Canada
    Pulm Pharmacol Ther 23:65-70. 2010
    ..We sought to determine the risk of new onset ocular hypertension or glaucoma requiring treatment, associated with the use of ICS in elderly patients treated for airways disease...
  10. ncbi request reprint Safety and effectiveness of long-acting inhaled beta-agonist bronchodilators when taken with inhaled corticosteroids
    Pierre Ernst
    McGill University, Montreal, Quebec, Canada
    Ann Intern Med 145:692-4. 2006
    ....
  11. ncbi request reprint Inhaled and nasal corticosteroid use and the risk of fracture
    Samy Suissa
    Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University Health Centre, Montreal, Quebec, Canada
    Am J Respir Crit Care Med 169:83-8. 2004
    ..In conclusion, the long-term use of inhaled and nasal corticosteroids at the usual recommended doses is not associated with a risk of fracture in older patients with respiratory disease...
  12. doi request reprint Inhaled corticosteroids and risk of tuberculosis in patients with respiratory diseases
    Paul Brassard
    Center for Clinical Epidemiology, Lady Davis Research Institute, Department of Medicine, Jewish General Hospital, Montreal, Quebec, Canada
    Am J Respir Crit Care Med 183:675-8. 2011
    ..Treatment with substantial doses of oral corticosteroids (OCS) for prolonged periods increases the risk of tuberculosis (TB). However, little is known about the effect of inhaled corticosteroids (ICS) in this respect...
  13. doi request reprint T Cells localize with proliferating smooth muscle alpha-actin+ cell compartments in asthma
    David Ramos-Barbon
    Meakins Christie Laboratories, McGill University, Montreal, PQ, Canada
    Am J Respir Crit Care Med 182:317-24. 2010
    ..Experimental studies showed that T cells adhere to ASM through vascular cell adhesion molecule-1 (VCAM-1) and drive ASM growth through direct contact between the T cells and smooth muscle alpha-actin (alpha-SMA)(+) cells...
  14. pmc Oral corticosteroid use and the risk of acute myocardial infarction in chronic obstructive pulmonary disease
    Laetitia Huiart
    Division of Clinical Epidemiology, Royal Victoria Hospital and Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada
    Can Respir J 13:134-8. 2006
    ..The impact of the use of oral corticosteroids on the risk of acute myocardial infarction (AMI) in a cohort of patients with COPD was studied...
  15. doi request reprint The use of inhaled corticosteroids and the risk of adrenal insufficiency
    Francesco Lapi
    Centre for Clinical Epidemiology, Lady Davis Research Institute, Jewish General Hospital, Montreal, QC, Canada
    Eur Respir J 42:79-86. 2013
    ..ICS at high doses appear to be a significant independent risk factor for adrenal insufficiency. Physicians prescribing ICS at such dosages should be sensitive to the signs and symptoms of adrenal insufficiency in their patients. ..
  16. doi request reprint Bronchodilator use and the risk of arrhythmia in COPD: part 2: reassessment in the larger Quebec cohort
    Machelle Wilchesky
    Donald Berman Maimonides Geriatric Centre, McGill University, Montreal, QC, Canada
    Chest 142:305-11. 2012
    ..A previous study suggested a potential increased risk of cardiac arrhythmia with new use of long-acting β-agonists and ipratropium bromide in patients with COPD, although conclusions were limited by the small cohort size...
  17. doi request reprint Psychologic distress and maladaptive coping styles in patients with severe vs moderate asthma
    Kim L Lavoie
    Hopital du Sacre Coeur de Montreal, Research Center, Department of Chest Medicine, J 3190, 5400 Gouin West, Montreal, QC, Canada H4J 1C5
    Chest 137:1324-31. 2010
    ..This study assessed levels of psychologic distress and a range of disease-relevant emotional and behavioral coping styles in patients with severe vs moderate asthma...
  18. ncbi request reprint A population-based evaluation of a regional asthma education centre
    Simone Cowan
    Department of Epidemiology and Biostatistics, and Division of Respiratory Medicine, McGill University Health Centre, Montreal, Quebec
    Can Respir J 11:39-44. 2004
    ..A population-based, ecological evaluation was conducted to determine the impact of a regional asthma education centre on reducing asthma-related morbidity and improving the quality of prescribing...
  19. ncbi request reprint Cardiovascular morbidity and mortality in COPD
    Laetitia Huiart
    Division of Clinical Epidemiology, Royal Victoria Hospital and Department of Epidemiology and Biostatistics, McGill University, 687 Pine Ave West, Ross 4 29, Montreal, QC, Canada, H3A 1A1
    Chest 128:2640-6. 2005
    ..COPD and cardiovascular disease (CVD) share common risk factors. We undertook to estimate rates of hospitalization and death from CVD in COPD patients relative to the general population...
  20. ncbi request reprint TNF-alpha antagonists and the prevention of hospitalisation for chronic obstructive pulmonary disease
    Samy Suissa
    Division of Clinical Epidemiology, McGill University Health Centre, Canada
    Pulm Pharmacol Ther 21:234-8. 2008
    ..TNF-alpha may be important in the pathogenesis of COPD. Consequently, the use of TNF-alpha antagonists has been advocated for its treatment...
  21. ncbi request reprint Inhaled corticosteroid use in asthma and the prevention of myocardial infarction
    Samy Suissa
    Division of Clinical Epidemiology, Royal Victoria Hospital, and Epidemiology and Biostatistics and Medicine, McGill University, Montreal, Quebec, Canada
    Am J Med 115:377-81. 2003
    ..We investigated whether inhaled corticosteroids, which are known to improve asthma control and reduce exacerbations, are associated with a lower rate of myocardial infarction...
  22. pmc Implementing practice guidelines: a workshop on guidelines dissemination and implementation with a focus on asthma and COPD
    Louis Philippe Boulet
    Hopital Laval, 2725 Chemin Sainte Foy, Quebec, Canada
    Can Respir J 13:5-47. 2006
    ..It is hoped that this event will be followed by other meetings that focus on how to improve the transfer of key recommendations from evidence-based guidelines into current care, and how to stimulate research to accomplish this...
  23. ncbi request reprint Adult Asthma Consensus Guidelines update 2003
    Catherine Lemiere
    Universite de Montreal, Montreal, Quebec
    Can Respir J 11:9A-18A. 2004
    ..Since the last revision of the 1999 Canadian Asthma Consensus Report, important new studies have highlighted the need to incorporate new information into the asthma guidelines...
  24. pmc Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality
    Samy Suissa
    Center for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, Montreal, Canada
    Thorax 67:957-63. 2012
    ..The long-term natural history of chronic obstructive pulmonary disease (COPD) in terms of successive severe exacerbations and mortality is unknown...
  25. ncbi request reprint Increased expression of ADAM33 and ADAM8 with disease progression in asthma
    Susan C Foley
    Meakins Christie Laboratories, McGill University, Montreal Chest Institute, Montreal, Quebec, Canada
    J Allergy Clin Immunol 119:863-71. 2007
    ..ADAM8 is strongly induced by allergens and T(H)2 cytokines in the lung in experimental asthma...
  26. doi request reprint Airway remodeling in subjects with severe asthma with or without chronic persistent airflow obstruction
    Marta Kaminska
    Meakins Christie Laboratories, Montreal, Quebec H2X 2P2, Canada
    J Allergy Clin Immunol 124:45-51.e1-4. 2009
    ..The patterns of airway remodeling and the biomarkers that distinguish different subtypes of severe asthma are unknown...
  27. ncbi request reprint Differences in airway cytokine profile in severe asthma compared to moderate asthma
    Joanne Shannon
    Montreal Chest Institute, Respiratory Division of McGill University Health Centre, Montreal, QC, Canada
    Chest 133:420-6. 2008
    ....
  28. doi request reprint Prevalence of obstructive sleep apnea-hypopnea in severe versus moderate asthma
    Joanne Y Julien
    Meakins Christie Laboratories, McGill University, Montreal, Quebec, Canada
    J Allergy Clin Immunol 124:371-6. 2009
    ..Previous studies have suggested a link between obstructive sleep apnea and poor asthma control, which may be mediated through airway inflammation, obesity, and other mechanisms...
  29. ncbi request reprint Facilitators and solutions for practicing optimal guided asthma self-management: the physician perspective
    Alexandrine J Lamontagne
    Clinical Research and Knowledge Transfer Unit on Childhood Asthma, Research Centre, CHU Sainte Justine, Montreal, Quebec
    Can Respir J 20:285-93. 2013
    ..To identify key solutions that facilitate the prescription of long-term asthma controller and provision of written self-management plans by physicians...
  30. doi request reprint Bronchodilator use and the risk of arrhythmia in COPD: part 1: Saskatchewan cohort study
    Machelle Wilchesky
    Donald Berman Maimonides Geriatric Centre, McGill University, Montreal, Canada
    Chest 142:298-304. 2012
    ..Bronchodilators are first-line therapy for COPD. There is some evidence that they may increase the risk of cardiac arrhythmias...
  31. pmc Effect of a web-based chronic disease management system on asthma control and health-related quality of life: study protocol for a randomized controlled trial
    Sara Ahmed
    School of Physical and Occupational Therapy, McGill University, 3654 Prom Sir William Osler, Montreal, QC, Canada
    Trials 12:260. 2011
    ....
  32. ncbi request reprint Leflunomide use and the risk of interstitial lung disease in rheumatoid arthritis
    Samy Suissa
    McGill University Health Centre, Montreal, Quebec, Canada
    Arthritis Rheum 54:1435-9. 2006
    ..To assess this risk, we conducted a population-based epidemiologic study...
  33. ncbi request reprint Bias in observational study of the effectiveness of nasal corticosteroids in asthma
    Samy Suissa
    Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University Health Centre, 687 Pine Avenue West, Montreal, Quebec, Canada H3A 1A1
    J Allergy Clin Immunol 115:714-9. 2005
    ..The approach to data analysis may have led to biased results because of misclassification of immortal time...
  34. pmc Inhaled corticosteroids in COPD and the risk of serious pneumonia
    Samy Suissa
    Departments of Epidemiology and Biostatistics and of Medicine, Center for Clinical Epidemiology, Lady Davis Research Institute, Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    Thorax 68:1029-36. 2013
    ..It is unclear whether the risk of pneumonia varies for different inhaled agents, particularly fluticasone and budesonide, and increases with the dose and long-term duration of use...
  35. doi request reprint Gender differences in survival following hospitalisation for COPD
    Anne V Gonzalez
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University Health Centre, Montreal, Canada
    Thorax 66:38-42. 2011
    ..Gender differences in survival and rate of rehospitalisation were investigated in a large cohort of elderly patients with chronic airflow obstruction hospitalised for COPD...
  36. ncbi request reprint Evaluating asthma control: a comparison of measures using an item response theory approach
    Sara Ahmed
    Department of Medicine, McGill University, Montreal, Canada
    J Asthma 44:547-54. 2007
    ..The IRT approach identified gaps in current measurement that need to be addressed to provide more precise evaluations of control required to accurately monitor changes in patient status...
  37. doi request reprint Fluoroquinolones and the risk of serious arrhythmia: a population-based study
    Francesco Lapi
    Centre for Clinical Epidemiology, Lady Davis Research Institute, Jewish General Hospital, Montreal, Quebec, Canada
    Clin Infect Dis 55:1457-65. 2012
    ..We assessed the risk of serious arrhythmia, defined as ventricular arrhythmia or sudden/unattended death identified in hospital discharge diagnoses, related to fluoroquinolones as a class as well as for each individual molecule...
  38. pmc Validation of The 30 Second Asthma Test as a measure of asthma control
    Sara Ahmed
    Faculty of Medicine, McGill University, Montreal, Canada
    Can Respir J 14:105-9. 2007
    ..Simple and efficient tools are needed to assess patient-reported symptoms so that they can be used with or without airway function to evaluate asthma control...
  39. pmc Childhood predictors of smoking in adolescence: a follow-up study of Montreal schoolchildren
    Margaret R Becklake
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, Montreal, Que
    CMAJ 173:377-9. 2005
    ..The factors that cause children to become smokers in adolescence remain unclear. Although parental smoking and peer pressure may play a role, physiological factors such as lung volume have also been identified...
  40. ncbi request reprint The determinants of prevalence of health complaints among young competitive swimmers
    Benoît Lévesque
    Institut National de Sante Publique du Quebec, 945 Ave Wolfe, G1V 5B3, Sainte Foy, Quebec, Canada
    Int Arch Occup Environ Health 80:32-9. 2006
    ..The objective of this study was to compare the prevalence of health complaints of young swimmers and young indoor soccer players and to evaluate the relationship between chloramine concentrations and the athletes' health complaints...
  41. doi request reprint Statins and the risk of interstitial lung disease: a cohort study
    Nathalie Saad
    Pulmonary Division, Jewish General Hospital, Montreal, Quebec, Canada
    Thorax 68:361-4. 2013
    ..Case reports have suggested that the use of statins may be associated with an increase in the risk of interstitial lung disease (ILD)...
  42. ncbi request reprint Altitude-related hypoxia: risk assessment and management for passengers on commerical aircraft
    Amir Mortazavi
    Division of Cardiology, McGill University, Montreal, Quebec, Canada
    Aviat Space Environ Med 74:922-7. 2003
    ....
  43. ncbi request reprint The impact of over-the-counter simvastatin on the number of statin prescriptions in the United Kingdom: a view from the General Practice Research Database
    Kristian B Filion
    McGill University, Division of Clinical Epidemiology, Royal Victoria Hospital, Montreal, Canada
    Pharmacoepidemiol Drug Saf 16:1-4. 2007
    ..We assessed the impact of this policy change on statin prescribing...
  44. ncbi request reprint Rates and patterns of chronic obstructive pulmonary disease exacerbations
    Magda Nunes de Melo
    Department of Epidemiology and Biostatistics, McGill University, Montreal, Canada
    Can Respir J 11:559-64. 2004
    ..Acute exacerbations of chronic obstructive pulmonary disease (COPD) are believed to be a common occurrence in patients with COPD and are known to be associated with considerable morbidity...
  45. ncbi request reprint Teaching time for metered-dose inhalers in the emergency setting
    Yuka Numata
    Respiratory Epidemiology Unit, McGill University, Montreal, PQ, Canada
    Chest 122:498-504. 2002
    ..We prospectively evaluated the time required to teach patients correct inhaler use for the emergency treatment of asthma and COPD, and patient factors associated with duration of teaching...
  46. ncbi request reprint Airway inflammation assessed by invasive and noninvasive means in severe asthma: eosinophilic and noneosinophilic phenotypes
    Catherine Lemiere
    Hopital du Sacre Coeur de Montreal, University of Montreal, Montreal, Quebec, Canada
    J Allergy Clin Immunol 118:1033-9. 2006
    ....
  47. ncbi request reprint The early course of newly diagnosed asthma
    Pierre Ernst
    Division of Clinical Epidemiology, Royal Victoria Hospital, and Pharmacoepidemiology Research Unit, McGill University Health Center, Montreal, Quebec, Canada
    Am J Med 112:44-8. 2002
    ..We describe the intensity of therapy for patients with newly diagnosed asthma and how it changed during subsequent years in relation to age, sex, and initial level of therapy...
  48. ncbi request reprint Evaluation of the use of an integrated drug information system by primary care physicians for vulnerable population
    Yuko Kawasumi
    Department of Epidemiology and Biostatistics, McGill University, and Division of Clinical Epidemiology, Royal Victoria Hospital, Montreal, Quebec H3A1A3, Canada
    Int J Med Inform 77:98-106. 2008
    ..To investigate whether an electronic prescribing and integrated drug information system was more likely to be used by primary care physicians for patients of low socioeconomic (SES) patients...
  49. ncbi request reprint Mega trials in COPD--clinical data analysis and design issues
    Samy Suissa
    Centre for Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital, Department of Epidemiology, McGill University, Montreal, Canada
    Pneumonol Alergol Pol 79:227-31. 2011
    ..With COPD one of the major causes of morbidity and mortality worldwide, mega trials such as TORCH and UPLIFT are much needed, but must achieve the utmost scientific rigour in their design and analysis...
  50. ncbi request reprint Newer disease-modifying antirheumatic drugs and the risk of serious hepatic adverse events in patients with rheumatoid arthritis
    Samy Suissa
    Division of Clinical Epidemiology, McGill University Health Centre, Montreal, Canada
    Am J Med 117:87-92. 2004
    ..We assessed the risk of hepatic events associated with the use of leflunomide and other DMARDs...
  51. ncbi request reprint Geographic and gender variability in the prevalence of bronchial responsiveness in Canada
    Jure Manfreda
    Department of Medicine, University of Manitoba, Winnipeg, MB, Canada
    Chest 125:1657-64. 2004
    ..We measured bronchial responsiveness using the standardized protocol of the European Community Respiratory Health Survey (ECRHS) in six sites in Canada, and compared prevalences across Canada with international sites...
  52. ncbi request reprint The Asthma Quiz for Kidz: a validated tool to appreciate the level of asthma control in children
    Francine M Ducharme
    Department of Pediatrics Montreal Children s Hospital McGill University Health Centre, 2300 Tupper Street, Montreal, Quebec H3H 1P3, Canada
    Can Respir J 11:541-6. 2004
    ..There is an urgent need to bridge the large gap between optimal and observed asthma control among Canadian children...
  53. pmc Airflow obstruction in young adults in Canada
    Manal Al-Hazmi
    University of Manitoba, Winnipeg, Manitoba
    Can Respir J 14:221-7. 2007
    ..The objective of the present study was to enumerate and characterize airflow obstruction in a random sample of Canadians aged 20 to 44 years...
  54. ncbi request reprint Adjustable maintenance dosing with budesonide/formoterol reduces asthma exacerbations compared with traditional fixed dosing: a five-month multicentre Canadian study
    J Mark FitzGerald
    The University of British Columbia, Vancouver, Canada
    Can Respir J 10:427-34. 2003
    ..Adjustable maintenance dosing with budesonide/formoterol in a single inhaler (Symbicort, AstraZeneca, Lund, Sweden) may provide a convenient means of maintaining asthma control with the minimum effective medication level...
  55. ncbi request reprint Patterns and determinants of compliance with inhaled steroids in adults with asthma
    Yves Lacasse
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Ste Foy, Qubec, Canada
    Can Respir J 12:211-7. 2005
    ..Patient compliance with inhaled corticosteroids (ICS) in asthma is considered to be suboptimal...
  56. pmc Canadian Pediatric Asthma Consensus guidelines, 2003 (updated to December 2004): introduction
    Allan Becker
    Department of Pediatrics and Child Health, University of Manitoba, Winnipeg, Man
    CMAJ 173:S12-4. 2005
    ..Since the last revision of the 1999 Canadian asthma consensus report, important new studies, particularly in children, have highlighted the need to incorporate this new information into asthma guidelines...
  57. ncbi request reprint Asthma and allergic rhinitis in Quebec children
    Benoît Lévesque
    Direction régionale de santé publique de Quebec, Beauport, Quebec City
    Can Respir J 11:343-8. 2004
    ..The Health and Social Survey of Quebec Children and Youth, conducted on representative samples of children nine, 13 and 16 years of age, provided data on the prevalence and determinants of asthma and allergic rhinitis in Quebec...
  58. ncbi request reprint Inhaled corticosteroids and fracture risk in COPD
    Samy Suissa
    Am J Respir Crit Care Med 170:94; author reply 94-5. 2004
  59. ncbi request reprint Safety and efficacy of HFA-134a beclomethasone dipropionate extra-fine aerosol over six months
    Louis Philippe Boulet
    Institut Universitaire de Cardiologie et de Pneumologie, l Université Laval, Hopital Laval, Sainte Foy, Quebec
    Can Respir J 11:123-30. 2004
    ..To compare the systemic safety and efficacy of hydrofluoroalkane beclomethasone dipropionate (HFA-BDP) extra-fine aerosol 800 microg/day with chlorofluorocarbon (CFC)-BDP 1500 microg/day...
  60. pmc Should combination therapy with inhaled corticosteroids and long-acting beta2-agonists be prescribed as initial maintenance treatment for asthma?
    Catherine Lemiere
    Service de Pneumologie, Universite de Montreal, Montreal, Que
    CMAJ 167:1008-9. 2002
  61. ncbi request reprint Correlates of quality of life in patients with asthma
    Laurent Laforest
    Centre Hospitalier Universitaire de Lyon, Lyon, France
    Ann Allergy Asthma Immunol 94:473-9. 2005
    ..Health-related quality of life (HRQOL) is a major outcome in asthma, but the relationships among HRQOL, characteristics of asthma, type of supervision, and sociodemographic characteristics of patients have not been thoroughly explored...
  62. ncbi request reprint Environmental measures and asthma
    Pierre Ernst
    Chest 122:1509-10. 2002
  63. ncbi request reprint Women and asthma: lessons from a gender analysis of the asthma in Canada survey
    Anna Day
    Division of Respiratory Medicine, University of Toronto, Toronto, Canada
    J Asthma 43:169-73. 2006
    ..To compare the degree of asthma control achieved by men and women with asthma in Canada and to explore differences in patient perspectives, treatments used, and health care resources used between men and women with asthma...
  64. ncbi request reprint Differences in airway remodeling between subjects with severe and moderate asthma
    Carmela Pepe
    Meakins Christie Laboratories, Montreal H2X2P2, Québec CA
    J Allergy Clin Immunol 116:544-9. 2005
    ..Several studies have suggested an association between these changes and disease severity. The relationship between the extent of remodeling and lung function is not well defined...
  65. ncbi request reprint Total and specific immunoglobulin E and their relationship to respiratory symptoms in Quebéc children and adolescents
    Benoît Lévesque
    CHUL Centre de recherche du CHUQ, Sainte Foy, Canada
    Can Respir J 12:426-32. 2005
    ..Respiratory disease is a major cause of morbidity in young people. It is now recognized that atopy plays an important role in the development of chronic respiratory symptoms in children...
  66. ncbi request reprint Increased glucocorticoid receptor-beta expression, but not decreased histone deacetylase 2, in severe asthma
    Celine Bergeron
    J Allergy Clin Immunol 117:703-5. 2006
  67. ncbi request reprint Increased risk of childhood asthma from antibiotic use in early life
    Anita L Kozyrskyj
    Faculty of Pharmacy, University of Manitoba, Winnipeg, MB, Canada R3T 2N2
    Chest 131:1753-9. 2007
    ....
  68. pmc Symposium on obesity and asthma - November 2, 2006
    Louis Philippe Boulet
    Centre de Pneumologie, Institut Universitaire de Cardiologie et de Pneumologie de l Universite Laval, Hopital Laval, Quebec
    Can Respir J 14:201-8. 2007
    ....
  69. ncbi request reprint Pesticide exposure and asthma
    Pierre Ernst
    Am J Respir Crit Care Med 165:563-4. 2002