P Ernst

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. ncbi request reprint Relative scarcity of asthma and atopy among rural adolescents raised on a farm
    P Ernst
    Unite de Recherche, Centre de Pneumologie, Hopital Laval, Quebec and the Respiratory Division, McGill University Health Centre, Montreal, Quebec, Canada
    Am J Respir Crit Care Med 161:1563-6. 2000
  2. ncbi request reprint Low-dose inhaled and nasal corticosteroid use and the risk of cataracts
    P Ernst
    Division of Clinical Epidemiology, Royal Victoria Hospital, 687 Pine Avenue West, Ross 4 29, Montreal, Quebec H3A 1A1, Canada
    Eur Respir J 27:1168-74. 2006
  3. ncbi request reprint Does seasonal employment in grain elevators increase nonspecific airways responsiveness?
    R E Dales
    Department of Epidemiology and Biostatistics, McGill University, Montreal, Canada
    J Occup Med 30:613-6. 1988
  4. ncbi request reprint Low-dose inhaled corticosteroids and the prevention of death from asthma
    S Suissa
    Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University Health Centre, Montreal, QC, Canada
    N Engl J Med 343:332-6. 2000
  5. ncbi request reprint Prevalence of bronchial hyperresponsiveness among HIV-infected men
    C D Poirier
    Respiratory Epidemiology Unit, Immunodeficiency Service and Department of Medicine, McGill University Health Centre, , , Canada
    Am J Respir Crit Care Med 164:542-5. 2001
  6. ncbi request reprint Inhaled corticosteroids and hospitalisation due to exacerbation of COPD
    J Bourbeau
    Respiratory Epidemiology Unit, Joint Depts of Epidemiology and Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada
    Eur Respir J 22:286-9. 2003
  7. ncbi request reprint Inhaled corticosteroids and the risk of a first exacerbation in COPD patients
    M N de Melo
    Dept of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada
    Eur Respir J 23:692-7. 2004
  8. ncbi request reprint Low-dose inhaled corticosteroids and the risk of acute myocardial infarction in COPD
    L Huiart
    Division of Clinical Epidemiology, Royal Victoria Hospital, and Dept of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada
    Eur Respir J 25:634-9. 2005
  9. ncbi request reprint What is new since the last (1999) Canadian Asthma Consensus Guidelines?
    L P Boulet
    Hopital Laval, Sainte Foy, Canada
    Can Respir J 8:5A-27A. 2001
  10. ncbi request reprint Inhaled corticosteroids: impact on asthma morbidity and mortality
    S Suissa
    Division of Clinical Epidemiology, McGill University Health Centre, Royal Victoria Hospital, 687 Pine Avenue West, Montreal, Quebec, Canada H3A 1A1
    J Allergy Clin Immunol 107:937-44. 2001

Detail Information

Publications31

  1. ncbi request reprint Relative scarcity of asthma and atopy among rural adolescents raised on a farm
    P Ernst
    Unite de Recherche, Centre de Pneumologie, Hopital Laval, Quebec and the Respiratory Division, McGill University Health Centre, Montreal, Quebec, Canada
    Am J Respir Crit Care Med 161:1563-6. 2000
    ..58 (95% CI 0.46 to 0.75) for atopy defined as a positive reaction to any one of 24 common inhaled allergens. These associations were also not significantly altered by adjusting for the difference in the number of siblings...
  2. ncbi request reprint Low-dose inhaled and nasal corticosteroid use and the risk of cataracts
    P Ernst
    Division of Clinical Epidemiology, Royal Victoria Hospital, 687 Pine Avenue West, Ross 4 29, Montreal, Quebec H3A 1A1, Canada
    Eur Respir J 27:1168-74. 2006
    ..Such an excess risk was not observed with nasal corticosteroids...
  3. ncbi request reprint Does seasonal employment in grain elevators increase nonspecific airways responsiveness?
    R E Dales
    Department of Epidemiology and Biostatistics, McGill University, Montreal, Canada
    J Occup Med 30:613-6. 1988
    ..Our results do not support the hypothesis that seasonal exposure to grain dust increases AR...
  4. ncbi request reprint Low-dose inhaled corticosteroids and the prevention of death from asthma
    S Suissa
    Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University Health Centre, Montreal, QC, Canada
    N Engl J Med 343:332-6. 2000
    ..Although inhaled corticosteroids are effective for the treatment of asthma, it is uncertain whether their use can prevent death from asthma...
  5. ncbi request reprint Prevalence of bronchial hyperresponsiveness among HIV-infected men
    C D Poirier
    Respiratory Epidemiology Unit, Immunodeficiency Service and Department of Medicine, McGill University Health Centre, , , Canada
    Am J Respir Crit Care Med 164:542-5. 2001
    ..Furthermore, the frequent occurrence of BHR in HIV-infected men who smoke (30.1%) suggests this group may be especially susceptible to the adverse effects of cigarette smoke...
  6. ncbi request reprint Inhaled corticosteroids and hospitalisation due to exacerbation of COPD
    J Bourbeau
    Respiratory Epidemiology Unit, Joint Depts of Epidemiology and Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada
    Eur Respir J 22:286-9. 2003
    ..No reduction in chronic obstructive pulmonary disease exacerbations requiring hospitalisation, in relation to the use of inhaled corticosteroids, were observed...
  7. ncbi request reprint Inhaled corticosteroids and the risk of a first exacerbation in COPD patients
    M N de Melo
    Dept of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada
    Eur Respir J 23:692-7. 2004
    ..51; 95% CI: 1.22-1.87), and it increased with increasing daily doses of ICS. Inhaled corticosteroids do not seem to be beneficial in reducing the risk of a first exacerbation of chronic obstructive pulmonary disease...
  8. ncbi request reprint Low-dose inhaled corticosteroids and the risk of acute myocardial infarction in COPD
    L Huiart
    Division of Clinical Epidemiology, Royal Victoria Hospital, and Dept of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada
    Eur Respir J 25:634-9. 2005
    ..However, a 32% reduction in the risk of AMI was observed for doses ranging 50-200 microg x day(-1). In conclusion, very low doses of inhaled corticosteroids may be associated with a reduction in the risk of acute myocardial infarction...
  9. ncbi request reprint What is new since the last (1999) Canadian Asthma Consensus Guidelines?
    L P Boulet
    Hopital Laval, Sainte Foy, Canada
    Can Respir J 8:5A-27A. 2001
    ..New developments, such as combination therapy, and recent major trials, such as the Children's Asthma Management Project (CAMP) study, are discussed...
  10. ncbi request reprint Inhaled corticosteroids: impact on asthma morbidity and mortality
    S Suissa
    Division of Clinical Epidemiology, McGill University Health Centre, Royal Victoria Hospital, 687 Pine Avenue West, Montreal, Quebec, Canada H3A 1A1
    J Allergy Clin Immunol 107:937-44. 2001
    ..In all, the evidence to date strongly indicates that regular use of inhaled corticosteroids, even at low doses, would prevent the major portion of asthma hospitalizations and deaths...
  11. pmc Inhaled short acting beta agonist use in COPD and the risk of acute myocardial infarction
    S Suissa
    Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University Health Centre, McGill University, Montreal, Canada
    Thorax 58:43-6. 2003
    ..We investigated this hypothesis in patients with COPD already at high risk of cardiac disease...
  12. pmc Regular use of inhaled corticosteroids and the long term prevention of hospitalisation for asthma
    S Suissa
    Division of Clinical Epidemiology, Royal Victoria Hospital, McGill University Health Centre, McGill University, Montreal, Canada
    Thorax 57:880-4. 2002
    ..Inhaled corticosteroids are effective at preventing asthma morbidity and mortality. Most studies, however, have focused on short term effects, raising uncertainty about their effectiveness in the long term...
  13. doi request reprint Methodological issues in therapeutic trials of COPD
    S Suissa
    McGill Pharmacoepidemiology Research Unit, McGill University Health Centre, Montreal, Quebec, Canada
    Eur Respir J 31:927-33. 2008
    ....
  14. pmc Relation of airway responsiveness to duration of work in a dusty environment
    P Ernst
    Department of Epidemiology and Biostatistics, McGill University, Montreal, Canada
    Thorax 44:116-20. 1989
    ..In studies of workforces a survivor effect of this nature will tend to weaken the relation between lung function abnormality and occupational exposure...
  15. ncbi request reprint Phenotype of IL-16-producing cells in bronchial mucosa: evidence for the human eosinophil and mast cell as cellular sources of IL-16 in asthma
    S Laberge
    Ste Justine Hospital, University of Montreal, Montreal, Canada
    Int Arch Allergy Immunol 119:120-5. 1999
    ..The aim of this study was to characterize and compare the phenotype of non-epithelial inflammatory cells that express IL-16 immunoreactivity in bronchial biopsies from non-atopic normal controls and atopic asthmatic subjects...
  16. ncbi request reprint Agreement in measuring socio-economic status: area-based versus individual measures
    K Demissie
    Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada
    Chronic Dis Can 21:1-7. 2000
    ..Caution should therefore be used in designing or interpreting the results of studies in which area-based SES measures are used to test hypotheses or control for confounding...
  17. ncbi request reprint Risk factors for bronchial hyperresponsiveness in late childhood and early adolescence
    P Ernst
    Dept of Epidemiology and Biostatistics, McGill University, Montreal, Quebec, Canada
    Eur Respir J 20:635-9. 2002
    ..In conclusion, the results of this study do not support a change in asthma phenotype with the onset of puberty. Pre- and postpuberty, the major determinant of bronchial hyperresponsiveness was skin sensitivity to mite allergen...
  18. ncbi request reprint Use of anti-inflammatory therapy and asthma mortality in Japan
    S Suissa
    Division of Clinical Epidemiology, Royal Victoria Hospital, Montreal, Quebec, Canada
    Eur Respir J 21:101-4. 2003
    ..The increasing use of inhaled corticosteroids and leukotriene receptor antagonists may have contributed to the significant reduction in asthma mortality among young asthmatics in Japan...
  19. ncbi request reprint Differences in proteoglycan deposition in the airways of moderate and severe asthmatics
    L Pini
    Meakins Christie Laboratories, Montreal Chest Institute, McGill University Hospital Centre, Universite de Montreal, Montreal, QC, Canada
    Eur Respir J 29:71-7. 2007
    ..Differences in the deposition of proteoglycans within the airway smooth muscle layer of moderate versus severe asthmatics potentially impact on the functional behaviour of the airway smooth muscle in these two groups of patients...
  20. ncbi request reprint Economic impact of using an immunostimulating agent to prevent severe acute exacerbations in patients with chronic obstructive pulmonary disease
    J P Collet
    Centre for Clinical Epidemiology and Community Studies, SMBD Jewish General Hospital, Montreal, Canada
    Can Respir J 8:27-33. 2001
    ....
  21. pmc Case-control study of lung cancer among sugar cane farmers in India
    D K Amre
    Department of Epidemiology, McGill University, Montreal, PQ, Canada
    Occup Environ Med 56:548-52. 1999
    ..To investigate the risk of lung cancer among sugar cane farmers and sugar mill workers...
  22. ncbi request reprint Obstructive and restrictive ventilatory impairment in polyvinylchloride fabrication workers
    P Ernst
    School of Occupational Health, McGill University, Montreal, Quebec, Canada
    Am J Ind Med 14:273-9. 1988
    ..While the specific exposures have not been identified, it appears that employment in PVC fabrication may be associated with both obstructive and restrictive ventilatory effects...
  23. ncbi request reprint Inhaled drug delivery: a practical guide to prescribing inhaler devices
    P Ernst
    Respiratory Division, Montreal General Hospital McGill University, Montreal, Canada
    Can Respir J 5:180-3. 1998
    ..Asthma education will be needed to instruct patients on the effective use of the numerous inhalation devices available...
  24. pmc Identification of persons with cardiorespiratory conditions who are at risk of dying from the acute effects of ambient air particles
    M S Goldberg
    Department of Medicine, McGill University, Montreal, Quebec, Canada
    Environ Health Perspect 109:487-94. 2001
    ..Further epidemiologic studies are required to confirm these findings...
  25. pmc Inhaled corticosteroids and mortality in COPD
    P Ernst
    Thorax 61:735. 2006
  26. pmc Inhaled corticosteroids moderate lung function decline in adults with asthma
    P Ernst
    Thorax 61:93-4. 2006
  27. ncbi request reprint Cost of autologous peripheral blood stem cell transplantation: the Norwegian experience from a multicenter cost study
    V Mishra
    Health Professional Support Department, Rikshospitalet University Hospital, Oslo, Norway
    Bone Marrow Transplant 35:1149-53. 2005
    ..Average total costs were considerably higher than actual DRG-based reimbursement from the government, indicating that the treatment of these patients was heavily subsidized by the basic hospital grants...
  28. ncbi request reprint Increased expression of interleukin-16 in bronchial mucosa of subjects with atopic asthma
    S Laberge
    Meakins Christie Laboratories and Montreal General Hospital, McGill University, Canada
    Am J Respir Cell Mol Biol 17:193-202. 1997
    ....
  29. ncbi request reprint N-acetylcysteine is unlikely to reduce hospitalisation for chronic obstructive pulmonary disease
    P Ernst
    Eur Respir J 22:865; author reply 865-6. 2003
  30. ncbi request reprint The pharmacoepidemiology of COPD: recent advances and methodological discussion
    P Burney
    Dept of Public Health Services, London, UK
    Eur Respir J Suppl 43:1s-44s. 2003
  31. ncbi request reprint Persistent asthma: disease control, resource utilisation and direct costs
    E Van Ganse
    Pharmacoepidemiology Unit, and Poison Centre, Claude Bernard University, Lyon, France
    Eur Respir J 20:260-7. 2002
    ..Therefore, if patients appropriately use prescribed control therapy, their use of medical resources may be reduced...