Nicolas Christou

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. pmc Weight gain after short- and long-limb gastric bypass in patients followed for longer than 10 years
    Nicolas V Christou
    Section of Bariatric Surgery, Division of General Surgery, McGill University Health Center, Montreal, Quebec, Canada
    Ann Surg 244:734-40. 2006
  2. pmc Five-year outcomes of laparoscopic adjustable gastric banding and laparoscopic Roux-en-Y gastric bypass in a comprehensive bariatric surgery program in Canada
    Nicolas Christou
    Section of Bariatric Surgery, Division of General Surgery, McGill University Health Centre, Montreal, Que
    Can J Surg 52:E249-58. 2009
  3. pmc Surgery decreases long-term mortality, morbidity, and health care use in morbidly obese patients
    Nicolas V Christou
    Section of Bariatric Surgery, Division of General Surgery, Department of Surgery, McGill University, Montreal, Quebec, Canada
    Ann Surg 240:416-23; discussion 423-4. 2004
  4. ncbi request reprint Analysis of the incidence and risk factors for wound infections in open bariatric surgery
    Nicolas V Christou
    Division of General Surgery, McGill University Health Center, Montreal, QC, Canada
    Obes Surg 14:16-22. 2004
  5. doi request reprint Bariatric surgery reduces cancer risk in morbidly obese patients
    Nicolas V Christou
    McGill University Health Center, Montreal, Quebec, Canada
    Surg Obes Relat Dis 4:691-5. 2008
  6. doi request reprint Impact of obesity and bariatric surgery on survival
    Nicolas V Christou
    Section of Bariatric Surgery, Department of Surgery, McGill University Health Center, McGill University, Room S6 24, 687 Pine Avenue West, Montreal, QC, H3A 1A1, Canada
    World J Surg 33:2022-7. 2009
  7. pmc Bariatric surgery waiting times in Canada
    Nicolas V Christou
    Department of Surgery, Division of General Surgery, McGill University, McGill University Health Centre, Montreal, Que
    Can J Surg 52:229-34. 2009
  8. ncbi request reprint Pre- and post-prandial plasma ghrelin levels do not correlate with satiety or failure to achieve a successful outcome after Roux-en-Y gastric bypass
    Nicolas V Christou
    Section of Bariatric Surgery, Division of General Surgery, McGill University Health Center, Montreal, QC, Canada
    Obes Surg 15:1017-23. 2005
  9. doi request reprint Use of critical care resources after laparoscopic gastric bypass: effect on respiratory complications
    Hanan El Shobary
    Department of Anesthesia, McGill University, Montreal, Quebec, Canada
    Surg Obes Relat Dis 4:698-702. 2008
  10. ncbi request reprint Effect of laparoscopic versus open gastric bypass surgery on postoperative pain and bowel function
    Hanan El Shobary
    Department of Anesthesia, McGill University, Royal Victoria Hospital, 687 Pine Avenue West, Montreal, Quebec, Canada H3A 1A1
    Obes Surg 16:437-42. 2006

Detail Information

Publications34

  1. pmc Weight gain after short- and long-limb gastric bypass in patients followed for longer than 10 years
    Nicolas V Christou
    Section of Bariatric Surgery, Division of General Surgery, McGill University Health Center, Montreal, Quebec, Canada
    Ann Surg 244:734-40. 2006
    ..To complete a long-term (>10 years) follow-up of patients undergoing isolated roux-en-Y gastric bypass for severe obesity...
  2. pmc Five-year outcomes of laparoscopic adjustable gastric banding and laparoscopic Roux-en-Y gastric bypass in a comprehensive bariatric surgery program in Canada
    Nicolas Christou
    Section of Bariatric Surgery, Division of General Surgery, McGill University Health Centre, Montreal, Que
    Can J Surg 52:E249-58. 2009
    ..Our aim was to compare outcomes between the laparoscopic Roux-en-Y gastric bypass (LRYGBP) and the laparoscopic adjustable gastric banding device (LAGBD) method with 5-year follow-up in a Canadian bariatric surgery centre...
  3. pmc Surgery decreases long-term mortality, morbidity, and health care use in morbidly obese patients
    Nicolas V Christou
    Section of Bariatric Surgery, Division of General Surgery, Department of Surgery, McGill University, Montreal, Quebec, Canada
    Ann Surg 240:416-23; discussion 423-4. 2004
    ..This study tested the hypothesis that weight-reduction (bariatric) surgery reduces long-term mortality in morbidly obese patients...
  4. ncbi request reprint Analysis of the incidence and risk factors for wound infections in open bariatric surgery
    Nicolas V Christou
    Division of General Surgery, McGill University Health Center, Montreal, QC, Canada
    Obes Surg 14:16-22. 2004
    ..The purpose of this study was to determine the incidence and risk factors for wound infection in open bariatric surgery...
  5. doi request reprint Bariatric surgery reduces cancer risk in morbidly obese patients
    Nicolas V Christou
    McGill University Health Center, Montreal, Quebec, Canada
    Surg Obes Relat Dis 4:691-5. 2008
    ..To assess the effect of bariatric surgery on the cancer risk of patients with morbid obesity because evidence is mounting of an association between obesity and cancer...
  6. doi request reprint Impact of obesity and bariatric surgery on survival
    Nicolas V Christou
    Section of Bariatric Surgery, Department of Surgery, McGill University Health Center, McGill University, Room S6 24, 687 Pine Avenue West, Montreal, QC, H3A 1A1, Canada
    World J Surg 33:2022-7. 2009
    ..Since the treatment of obesity-associated conditions is very costly, bariatric surgery also results in significant reductions in healthcare costs with a return on investment of 3 years. It is not just weight loss, it is health gain...
  7. pmc Bariatric surgery waiting times in Canada
    Nicolas V Christou
    Department of Surgery, Division of General Surgery, McGill University, McGill University Health Centre, Montreal, Que
    Can J Surg 52:229-34. 2009
    ..The only permanent treatment of severe or morbid obesity is bariatric surgery. Access to bariatric surgery is very limited in Canada. We sought to collect accurate data on waiting times for the procedure...
  8. ncbi request reprint Pre- and post-prandial plasma ghrelin levels do not correlate with satiety or failure to achieve a successful outcome after Roux-en-Y gastric bypass
    Nicolas V Christou
    Section of Bariatric Surgery, Division of General Surgery, McGill University Health Center, Montreal, QC, Canada
    Obes Surg 15:1017-23. 2005
    ..We tested the hypothesis that the amount of weight lost after Roux-en-Y gastric bypass (RYGBP) correlates with plasma ghrelin levels...
  9. doi request reprint Use of critical care resources after laparoscopic gastric bypass: effect on respiratory complications
    Hanan El Shobary
    Department of Anesthesia, McGill University, Montreal, Quebec, Canada
    Surg Obes Relat Dis 4:698-702. 2008
    ..This study assessed the incidence of respiratory complications in patients undergoing laparoscopic gastric bypass before and after implementation of the new ICU admission criteria...
  10. ncbi request reprint Effect of laparoscopic versus open gastric bypass surgery on postoperative pain and bowel function
    Hanan El Shobary
    Department of Anesthesia, McGill University, Royal Victoria Hospital, 687 Pine Avenue West, Montreal, Quebec, Canada H3A 1A1
    Obes Surg 16:437-42. 2006
    ..This study was designed to assess postoperative pain and bowel function in morbidly obese patients undergoing Roux-en-Y gastric bypass (RYGBP) performed either by open or laparoscopic technique...
  11. ncbi request reprint Hypertonic saline resuscitation attenuates neutrophil lung sequestration and transmigration by diminishing leukocyte-endothelial interactions in a two-hit model of hemorrhagic shock and infection
    Jose L Pascual
    Division of General Surgery, McGill University Health Center, Montreal, Quebec, Canada
    J Trauma 54:121-30; discussion 130-2. 2003
    ..We hypothesized that HTS resuscitation reduces early in vivo endothelial cell (EC)-PMN interactions and late lung PMN sequestration in a two-hit model of hemorrhagic shock followed by mimicked infection...
  12. ncbi request reprint The impact of weight reduction surgery on health-care costs in morbidly obese patients
    John S Sampalis
    Section of Bariatric Surgery, Division of General Surgery, McGill University Health Centre, Montreal, Quebec, Canada
    Obes Surg 14:939-47. 2004
    ..The treatment of obesity and related comorbidities are significant financial burdens and sources of resource expenditure. This study was conducted in order to assess the impact of weight-reduction surgery on health-related costs...
  13. doi request reprint Small bowel obstruction due to retrograde intussusception after laparoscopic Roux-en-Y gastric bypass
    Evangelos Efthimiou
    Section of Bariatric Surgery, Division of General Surgery, McGill University Health Centre, Royal Victoria Hospital, Montreal, Quebec, Canada
    Obes Surg 19:378-80. 2009
    ..Emergency care doctors should be aware of this specific complication in bariatric patients and seek expert advice...
  14. ncbi request reprint Impact of bariatric surgery on cardiovascular and musculoskeletal morbidity
    John S Sampalis
    Department of Surgery, McGill University Health Centre, Montreal, Quebec, Canada
    Surg Obes Relat Dis 2:587-91. 2006
    ..The objective of the study was to assess the impact of bariatric surgery on cardiovascular and musculoskeletal morbidity...
  15. pmc Hypertonic saline resuscitation of hemorrhagic shock diminishes neutrophil rolling and adherence to endothelium and reduces in vivo vascular leakage
    Jose L Pascual
    Division of General Surgery and Department of Pathology, McGill University Health Center, McGill University, Montreal, Canada
    Ann Surg 236:634-42. 2002
    ..To evaluate the in vivo effects of hypertonic saline (HTS) resuscitation on the interactions of endothelial cells (ECs) and polymorphonuclear neutrophils (PMNs) and vascular permeability after hemorrhagic shock...
  16. ncbi request reprint Intussusception after laparoscopic Roux-en-Y gastric bypass
    Salman Al-Sabah
    Section of Bariatric Surgery, Division of General Surgery, McGill University Health Center, Montreal, Quebec, Canada
    Surg Obes Relat Dis 4:205-9. 2008
  17. ncbi request reprint Intra-abdominal sepsis attenuates local inflammation-mediated increases in microvascular permeability at remote sites in mice in vivo
    Lorenzo E Ferri
    Department of Surgery, McGill University Health Center, McGill University, Montreal, Quebec, Canada
    Surgery 135:187-95. 2004
    ....
  18. ncbi request reprint Soluble L-selectin attenuates tumor necrosis factor-alpha-mediated leukocyte adherence and vascular permeability: a protective role for elevated soluble L-selectin in sepsis
    Lorenzo E Ferri
    Department of Surgery and Microbiology, McGill University Health Centre, McGill University, Montreal, Quebec, Canada
    Crit Care Med 30:1842-7. 2002
    ....
  19. doi request reprint L-selectin shedding in sepsis limits leukocyte mediated microvascular injury at remote sites
    Lorenzo E Ferri
    Department of Surgery, McGill University, Montreal, Canada
    Surgery 145:384-91. 2009
    ..We hypothesized that failure to shed L-selectin in systemic inflammation would result in increased local inflammation-induced leukocyte adherence and microvascular leakage...
  20. ncbi request reprint Hypertonic saline and the microcirculation
    Jose L Pascual
    Division of General Surgery, McGill University Health Center, Montreal, Quebec, Canada
    J Trauma 54:S133-40. 2003
    ..Better characterization of microcirculatory effects by hypertonic saline may provide mechanisms for improved morbidity and mortality associated with hypertonic resuscitation...
  21. ncbi request reprint Waist-to-hip ratio is associated with pulmonary gas exchange in the morbidly obese
    Gerald S Zavorsky
    Department of Anesthesia, McGill University Health Center, Montreal General Hospital, 1650 Cedar Ave, Room D10 144, Montreal, QC, Canada H3G 1A4
    Chest 131:362-7. 2007
    ..Morbidly obese individuals (ie, body mass index [BMI], > or = 40 kg/m2) may have a pulmonary gas exchange impairment due to the large fat mass surrounding their abdomen...
  22. doi request reprint Anastomotic leaks after bariatric surgery: it is the host response that matters
    Salman Al-Sabah
    Department of General Surgery, McGill University, Montreal, Quebec, Canada
    Surg Obes Relat Dis 4:152-7; discussion 157-8. 2008
    ..We tested the hypothesis that not all patients with an anastomotic leak after bariatric surgery present with clinical symptoms and that their outcome is dependent on the aggressiveness of the host inflammatory response...
  23. ncbi request reprint Effect of bariatric surgery on long-term mortality
    Nicolas V Christou
    McGill University, Section of Bariatric Surgery, McGill University Health Center, Montreal, Quebec, Canada
    Adv Surg 39:165-79. 2005
  24. pmc Alteration of chemoattractant receptor expression regulates human neutrophil chemotaxis in vivo
    Andrew J E Seely
    Division of General Surgery, McGill University Health Center, Montreal, Quebec, Canada
    Ann Surg 235:550-9. 2002
    ..To elucidate the mechanisms that regulate human neutrophil delivery in vivo, as well as the mechanisms that lead to observed reduction in polymorphonuclear (PMN) delivery to remote sites in septic patients...
  25. doi request reprint Fibrin sealant associated with increased body temperature and leukocytosis after laparoscopic gastric bypass
    Evangelos Efthimiou
    Section of Bariatric Surgery, Division of General Surgery, McGill University Health Center, Montreal, Quebec, Canada
    Surg Obes Relat Dis 6:46-9. 2010
    ..We studied FS use and its effect on the clinical inflammatory response after laparoscopic Roux-en-Y gastric bypass...
  26. ncbi request reprint Patient controlled i.v. analgesia is an acceptable pain management strategy in morbidly obese patients undergoing gastric bypass surgery. A retrospective comparison with epidural analgesia
    Roshanak Charghi
    Department of Anesthesia, Royal Victoria Hospital, Montreal, Quebec, Canada
    Can J Anaesth 50:672-8. 2003
    ..We retrospectively compared the postoperative periods in all patients undergoing this procedure in our institution between November 1999 and November 2001...
  27. ncbi request reprint Pilot study examining the frequency of several gene polymorphisms in a morbidly obese population
    Dimitri J Koumanis
    Resident in General Surgery, McGill University Health Centre, Royal Victoria Hospital, Montreal, QC, Canada
    Obes Surg 12:759-64. 2002
    ..We examined the frequency of these polymorphisms in patients with a BMI > 40 and compared them to individuals with a BMI < 30. Our hypothesis was that these polymorphisms would occur more frequently in the obese population...
  28. ncbi request reprint Medicare and bariatric surgery
    John G Kral
    American Society for Bariatric Surgery, Gainesville, Florida 32607, USA
    Surg Obes Relat Dis 1:35-63. 2005
  29. doi request reprint Alveolar-membrane diffusing capacity improves in the morbidly obese after bariatric surgery
    Gerald S Zavorsky
    Department of Obstetrics, Gynecology and Women s Health, School of Medicine, Saint Mary s Health Center, Saint Louis University, 6420 Clayton Road, Suite 290, Saint Louis, MO 63117, USA
    Obes Surg 18:256-63. 2008
    ..The purpose of this study was to measure pulmonary diffusing capacity for NO (DLNO) as an index of DmCO pre- and postbariatric surgery in the morbidly obese...
  30. pmc Early results after laparoscopic Roux-en-Y gastric bypass: effect of the learning curve
    Christopher G Andrew
    Department of Surgery, University of Manitoba, St Boniface General Hospital, Winnipeg
    Can J Surg 49:417-21. 2006
    ..This study was performed to evaluate the safety and short-term efficacy of laparoscopic Roux-en-Y gastric bypass (LRYGB) for morbid obesity and to describe the relation between learning curve and short-term outcomes...
  31. ncbi request reprint Poor compensatory hyperventilation in morbidly obese women at peak exercise
    Gerald S Zavorsky
    Department of Obstetrics, Gynecology and Women s Health, Saint Louis University School of Medicine, Saint Mary s Health Center, 6420 Clayton Road, Room 290, St Louis, MO 63117, United States
    Respir Physiol Neurobiol 159:187-95. 2007
    ..In conclusion, morbidly obese women have poorer exercise capacity, cardiac efficiency, and compensatory hyperventilation at peak exercise, and poorer gas exchange at rest compared to physically active, non-obese women...
  32. pmc Science review: Cell membrane expression (connectivity) regulates neutrophil delivery, function and clearance
    Andrew J E Seely
    Division of Thoracic Surgery, University of Ottawa, Ottawa, Ontario, Canada
    Crit Care 7:291-307. 2003
    ..Thus, not only does the neutrophil membrane mediate the processes that characterize the neutrophil lifecycle, but characterization of neutrophil membrane expression represents a technology with which to evaluate neutrophil function...
  33. doi request reprint Compensatory exercise hyperventilation is restored in the morbidly obese after bariatric surgery
    Gerald S Zavorsky
    Department of Obstetrics, Gynecology and Women s Health, School of Medicine, Saint Mary s Health Center, Saint Louis University, 6420 Clayton Road, Room 290, Saint Louis, MO 63117, USA
    Obes Surg 18:549-59. 2008
    ..The objective was to examine pulmonary gas exchange and the compensatory hyperventilatory response during exercise pre- and post-weight reduction surgery in obese subjects...
  34. pmc Ertapenem versus piperacillin/tazobactam in the treatment of complicated intraabdominal infections: results of a double-blind, randomized comparative phase III trial
    Joseph S Solomkin
    Department of Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0558, USA
    Ann Surg 237:235-45. 2003
    ..To examine the clinical efficacy and safety of ertapenem, a novel beta-lactam agent with wide activity against common pathogens encountered in intraabdominal infection...