Graham Bell

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. pmc The incidental response to uniform natural selection
    Graham Bell
    Department of Biology, McGill University, Montreal, Quebec, Canada
    Biol Lett 9:20130215. 2013
  2. doi request reprint Experimental evolution of heterotrophy in a green alga
    Graham Bell
    Department of Biology, McGill University, 1205 Avenue Docteur Penfield, Montreal, Quebec H3A 1B1, Canada
    Evolution 67:468-76. 2013
  3. pmc Evolutionary rescue and the limits of adaptation
    Graham Bell
    Biology Department, McGill University, 1205 Avenue Docteur Penfield, Montreal, Quebec, Canada
    Philos Trans R Soc Lond B Biol Sci 368:20120080. 2013
  4. pmc Evolutionary rescue of a green alga kept in the dark
    Graham Bell
    Department of Biology, McGill University, Montreal, Quebec, Canada
    Biol Lett 9:20120823. 2013
  5. ncbi request reprint Arming the enemy: the evolution of resistance to self-proteins
    Graham Bell
    Biology Department, McGill University, 1205 Ave Dr Penfield, Montreal, Quebec, Canada H3A 1B1
    Microbiology 149:1367-75. 2003
  6. ncbi request reprint Experimental sexual selection in Chlamydomonas
    G Bell
    Biology Department, McGill University, Montreal, Quebec, Canada
    J Evol Biol 18:722-34. 2005
  7. ncbi request reprint The evolution of trophic structure
    G Bell
    Redpath Museum and Biology Department, McGill University, Montreal, Quebec, Canada
    Heredity (Edinb) 99:494-505. 2007
  8. pmc The interpretation of biological surveys
    Graham Bell
    Redpath Museum and Biology Department, McGill University, Montreal, Quebec, H3A 1B1 Canada
    Proc Biol Sci 270:2531-42. 2003
  9. ncbi request reprint The comparative evidence relating to functional and neutral interpretations of biological communities
    Graham Bell
    Redpath Museum, McGill University, Montreal, Quebec, Canada
    Ecology 87:1378-86. 2006
  10. doi request reprint Evolutionary rescue can prevent extinction following environmental change
    Graham Bell
    Biology Department, McGill University, Montreal, H3A 1B1 QC, Canada
    Ecol Lett 12:942-8. 2009

Collaborators

Detail Information

Publications47

  1. pmc The incidental response to uniform natural selection
    Graham Bell
    Department of Biology, McGill University, Montreal, Quebec, Canada
    Biol Lett 9:20130215. 2013
    ..The differences between closely related species or varieties may likewise arise, in similar circumstances, by sampling error rather than natural selection...
  2. doi request reprint Experimental evolution of heterotrophy in a green alga
    Graham Bell
    Department of Biology, McGill University, 1205 Avenue Docteur Penfield, Montreal, Quebec H3A 1B1, Canada
    Evolution 67:468-76. 2013
    ..Specialized autotrophs and heterotrophs may often evolve in algae through long-term shifts in the conditions of growth...
  3. pmc Evolutionary rescue and the limits of adaptation
    Graham Bell
    Biology Department, McGill University, 1205 Avenue Docteur Penfield, Montreal, Quebec, Canada
    Philos Trans R Soc Lond B Biol Sci 368:20120080. 2013
    ..Neither the standing genetic variation of small populations nor the mutation supply of large populations, however, may be sufficient to provide evolutionary rescue for most populations...
  4. pmc Evolutionary rescue of a green alga kept in the dark
    Graham Bell
    Department of Biology, McGill University, Montreal, Quebec, Canada
    Biol Lett 9:20120823. 2013
    ..The greater probability of evolutionary rescue suggests a general reason for the prevalence of sexual species...
  5. ncbi request reprint Arming the enemy: the evolution of resistance to self-proteins
    Graham Bell
    Biology Department, McGill University, 1205 Ave Dr Penfield, Montreal, Quebec, Canada H3A 1B1
    Microbiology 149:1367-75. 2003
    ..If so, the introduction of these substances into general use may provoke the evolution of resistance to our own defence proteins and thus compromise our natural defences against infection...
  6. ncbi request reprint Experimental sexual selection in Chlamydomonas
    G Bell
    Biology Department, McGill University, Montreal, Quebec, Canada
    J Evol Biol 18:722-34. 2005
    ..It is possible that selection experiments of this kind are unlikely to induce sexual isolation because mating-type genes evolve in a saltatory fashion...
  7. ncbi request reprint The evolution of trophic structure
    G Bell
    Redpath Museum and Biology Department, McGill University, Montreal, Quebec, Canada
    Heredity (Edinb) 99:494-505. 2007
    ..It both imposes selection on each species and itself responds to selection, but selection does not necessarily maximize stability, productivity or any other community property...
  8. pmc The interpretation of biological surveys
    Graham Bell
    Redpath Museum and Biology Department, McGill University, Montreal, Quebec, H3A 1B1 Canada
    Proc Biol Sci 270:2531-42. 2003
    ....
  9. ncbi request reprint The comparative evidence relating to functional and neutral interpretations of biological communities
    Graham Bell
    Redpath Museum, McGill University, Montreal, Quebec, Canada
    Ecology 87:1378-86. 2006
    ....
  10. doi request reprint Evolutionary rescue can prevent extinction following environmental change
    Graham Bell
    Biology Department, McGill University, Montreal, H3A 1B1 QC, Canada
    Ecol Lett 12:942-8. 2009
    ..These results demonstrate that rapid evolution is an important component of the response of small populations to environmental change...
  11. doi request reprint The oligogenic view of adaptation
    G Bell
    Department of Biology, McGill University, Montreal, Quebec, Canada H3A 181
    Cold Spring Harb Symp Quant Biol 74:139-44. 2009
    ..Nevertheless, recent attempts to predict how very simple genomes change have been surprisingly successful, and we may be close to a new predictive understanding of the genetic basis of adaptation...
  12. pmc Experimental genomics of fitness in yeast
    Graham Bell
    Biology Department, McGill University, 1205 Avenue Docteur Penfield, Montreal, Quebec, Canada
    Proc Biol Sci 277:1459-67. 2010
    ..The properties of the yeast deletion set provide us with the first genome-wide account of fitness, although transferring these conclusions to the field is a task for the future...
  13. pmc Fluctuating selection: the perpetual renewal of adaptation in variable environments
    Graham Bell
    Department of Biology, McGill University, Montreal, Quebec, Canada
    Philos Trans R Soc Lond B Biol Sci 365:87-97. 2010
    ....
  14. doi request reprint Parallel evolution of multidrug-resistance in Salmonella enterica isolated from swine
    Gabriel G Perron
    Department of Biology, McGill University, Montreal, QC, Canada
    FEMS Microbiol Lett 281:17-22. 2008
    ....
  15. ncbi request reprint Rewinding the tape: selection of algae adapted to high CO2 at current and pleistocene levels of CO2
    Sinead Collins
    McGill University, Department of Biology, 1205 Ave Dr Penfield, Montreal H3A 1BI, Canada
    Evolution 60:1392-401. 2006
    ..Adaptation to ambient and glacial-era levels of CO2 produced a range of phenotypes, suggesting that chance rather than selective history contributes to the divergence of replicate populations in this system...
  16. pmc A reservoir of drug-resistant pathogenic bacteria in asymptomatic hosts
    Gabriel G Perron
    Department of Biology, McGill University, Montreal, Quebec, Canada
    PLoS ONE 3:e3749. 2008
    ..This study shows how agricultural practice and human intervention may lead and influence the evolution of a hidden reservoir of pathogens, with important implications for human health...
  17. pmc The evolution of a pleiotropic fitness tradeoff in Pseudomonas fluorescens
    R Craig MacLean
    Department of Biology, McGill University, 1205 Avenue Docteur Penfield, Montreal, QC, Canada H3A 1B1
    Proc Natl Acad Sci U S A 101:8072-7. 2004
    ..These results provide a possible explanation of conflicting accounts for the cost of specialization...
  18. ncbi request reprint The ecology and genetics of fitness in Chlamydomonas. XII. Repeated sexual episodes increase rates of adaptation to novel environments
    Oliver Kaltz
    Department of Biology, McGill University, Montreal, Quebec, Canada
    Evolution 56:1743-53. 2002
    ..These results support the Weismann-Fisher-Muller hypothesis for the maintenance of sex in natural populations...
  19. ncbi request reprint Changes in C uptake in populations of Chlamydomonas reinhardtii selected at high CO2
    Sinead Collins
    Biology Department, McGill University, 1205 Avenue Dr Penfield, Montreal, Quebec, Canada
    Plant Cell Environ 29:1812-9. 2006
    ..This shows how predictions about the properties of communities in the future can be influenced by the effect of natural selection...
  20. pmc Mutations of intermediate effect are responsible for adaptation in evolving Pseudomonas fluorescens populations
    Rowan D H Barrett
    McGill University, Department of Biology, 1205 Avenue Doctor Penfield, Montreal, Quebec H3A 1B1, Canada
    Biol Lett 2:236-8. 2006
    ..Our experiment suggests that the initial stages of adaptation to stressful environments will involve the substitution of mutations with large effect on fitness...
  21. ncbi request reprint The ecology and genetics of fitness in Chlamydomonas. XIII. Fitness of long-term sexual and asexual populations in benign environments
    Sébastien Renaut
    Department of Biology, McGill University, Montreal, Quebec H3H JBI, Canada
    Evolution 60:2272-9. 2006
    ..Recombination between these genotypes reduces mean fitness and creates genetic variance for fitness. This may provide fuel for continued selection should the environment change...
  22. ncbi request reprint The dynamics of diversification in evolving Pseudomonas populations
    Rowan D H Barrett
    Department of Biology, McGill University, Montreal, Quebec, Canada
    Evolution 60:484-90. 2006
    ..Our findings suggest that ecological opportunity provided by environmental complexity plays a major role in the evolution and maintenance of diversity...
  23. pmc Divergent evolution during an experimental adaptive radiation
    R Craig MacLean
    Department of Biology, McGill University, 1205 Drive Penfield, Montreal, Quebec H3A 1B1, Canada
    Proc Biol Sci 270:1645-50. 2003
    ....
  24. ncbi request reprint Phenotypic consequences of 1,000 generations of selection at elevated CO2 in a green alga
    Sinead Collins
    Biology Department, McGill University, Montreal, Quebec H3A 1B1, Canada
    Nature 431:566-9. 2004
    ..These lines also grew poorly at ambient concentrations of CO2. We tentatively attribute this outcome to the accumulation of conditionally neutral mutations in genes affecting the carbon concentration mechanism...
  25. pmc Evolutionary rescue and adaptation to abrupt environmental change depends upon the history of stress
    Andrew Gonzalez
    Biology Department, McGill University, 1205 Avenue Docteur Penfield, Montreal, Quebec, Canada
    Philos Trans R Soc Lond B Biol Sci 368:20120079. 2013
    ....
  26. ncbi request reprint Macroevolution simulated with autonomously replicating computer programs
    Gabriel Yedid
    Biology Department, McGill University, 1205 Avenue Dr Penfield, Montreal, Quebec, Canada H3A 1B1
    Nature 420:810-2. 2002
    ....
  27. doi request reprint Adaptation and evolutionary rescue in metapopulations experiencing environmental deterioration
    Graham Bell
    Department of Biology, McGill University, 1205 Ave Docteur Penfield, Montreal, Quebec H3A 1B1, Canada
    Science 332:1327-30. 2011
    ..Adaptation was surprisingly frequent and rapid in small peripheral populations. Thus, evolutionary dynamics affect both the persistence and the range of a species after environmental deterioration...
  28. ncbi request reprint Experimental evolution of Pseudomonas fluorescens in simple and complex environments
    Rowan D H Barrett
    Department of Biology, McGill University, 1205 Avenue Doctor Penfield, Montreal, Quebec H3A 1B1, Canada
    Am Nat 166:470-80. 2005
    ....
  29. pmc Cross-Cordillera exchange mediated by the Panama Canal increased the species richness of local freshwater fish assemblages
    Scott A Smith
    Department of Biology, McGill University, Montreal, Quebec, Canada
    Proc Biol Sci 271:1889-96. 2004
    ..Moreover, the results of this unintentional experiment demonstrate that community composition and species richness were regulated by the regional process of dispersal, rather than by local processes such as competition and predation...
  30. ncbi request reprint Neutral macroecology
    G Bell
    Redpath Museum, McGill University, Montreal, Quebec, Canada H3A 2K6
    Science 293:2413-8. 2001
    ..More fundamentally, neutral community models provide a general theory for biodiversity and conservation biology capable of predicting the fundamental processes and patterns of community ecology...
  31. ncbi request reprint Diversity peaks at intermediate productivity in a laboratory microcosm
    R Kassen
    Department of Biology, McGill University, Montreal, Quebec, Canada
    Nature 406:508-12. 2000
    ..Our result provides experimental evidence that the unimodal relationship often observed in natural communities can be caused by selection for specialized types in a heterogeneous environment...
  32. pmc Sex and the spread of retrotransposon Ty3 in experimental populations of Saccharomyces cerevisiae
    C Zeyl
    Department of Biology, McGill University, Montreal, Quebec, Canada
    Genetics 143:1567-77. 1996
    ..Repressed Ty3 elements spread in sexual populations, by increasing sexual fitness. These results indicate that active Ty3 elements are more likely to become established in sexual populations than in asexual populations...
  33. ncbi request reprint The ecology and genetics of fitness in Chlamydomonas. X. The relationship between genetic correlation and genetic distance
    R Kassen
    Department of Biology and Redpath Museum, McGill University, Montreal, Quebec, Canada
    Evolution 54:425-32. 2000
    ..These results suggest that divergent selection will be more likely to maintain genetic variation when environments are strongly contrasted and genotypes widely divergent...
  34. pmc Long-term culture at elevated atmospheric CO2 fails to evoke specific adaptation in seven freshwater phytoplankton species
    Etienne Low-Décarie
    Department of Biology, McGill University, 1205 Avenue Docteur Penfield, Montreal, Quebec, Canada, H3A 1B1
    Proc Biol Sci 280:20122598. 2013
    ..We conclude that the physiology of carbon utilization may be conserved in natural freshwater phytoplankton communities experiencing rising atmospheric CO(2) levels, without substantial evolutionary change...
  35. doi request reprint Saccharomyces sensu stricto as a model system for evolution and ecology
    Taissa Replansky
    Department of Biology, McGill University, 1205 Dr Penfield, Montreal, QC H3A 1B1, Canada
    Trends Ecol Evol 23:494-501. 2008
    ..Here we review the current knowledge of the evolution and ecology of S. cerevisiae and closely related species in the Saccharomyces sensu stricto group, and suggest future research directions...
  36. ncbi request reprint Genotypic diversity and antimicrobial resistance in asymptomatic Salmonella enterica serotype Typhimurium DT104
    Gabriel G Perron
    Department of Biology, McGill University, 1205 Avenue Dr Penfield, Montreal, H3A 1B1 Que, Canada
    Infect Genet Evol 7:223-8. 2007
    ..We thus concluded that an important aspect of Salmonella population structure and ecology is overlooked in investigations of disease-associated isolates...
  37. pmc Experimental evolution of resistance to an antimicrobial peptide
    Gabriel G Perron
    Department of Biology, McGill University, 1205 Avenue Dr Penfield, Montreal, Que H3A 1B1, Canada
    Proc Biol Sci 273:251-6. 2006
    ....
  38. doi request reprint Adaptation of experimental yeast populations to stressful conditions in relation to population size
    P Samani
    Department of Biology, McGill University, Montreal, QC, Canada
    J Evol Biol 23:791-6. 2010
    ..This suggests that the pattern of genetic correlation between successively higher levels of stress is an important factor in facilitating evolutionary rescue...
  39. doi request reprint Evolutionary rescue of sexual and asexual populations in a deteriorating environment
    Josianne Lachapelle
    Biology Department, McGill University, 1205 Avenue Docteur Penfield, Montreal, Quebec H3A 1B1, Canada
    Evolution 66:3508-18. 2012
    ..The evolutionary rescue events observed in this study provide evidence that major shifts in ways of life can arise within short time frames through the action of natural selection in sexual populations...
  40. ncbi request reprint Variation in growth rate in a natural assemblage of unicellular green soil algae
    H P Koelewijn
    Redpath Museum and Department of Biology, McGill University, 859 Sherbrooke Street West, Montreal, Quebec, Canada, H3A 2K6
    Heredity (Edinb) 87:162-71. 2001
    ..Correlated responses were negative when performance in widely different (light and dark) environments was compared, but positive for more similar environments (high and low nutrient concentrations)...
  41. ncbi request reprint An experimental test of local adaptation in soil bacteria
    Dorothée Belotte
    Biology Department, McGill University, Montreal, Quebec H3A 1B1, Canada
    Evolution 57:27-36. 2003
    ..0577 per meter. These figures are similar to those previously reported for plants. This selection gradient has matched the bacterial assemblage to the edaphic structure of the environment, although the fit is far from perfect...
  42. ncbi request reprint The ecology and genetics of fitness in Chlamydomonas. VIII. The dynamics of adaptation to novel environments after a single episode of sex
    Nick Colegrave
    Department of Biology, McGill University, Montreal, Quebec, Canada
    Evolution 56:14-21. 2002
    ..Although recombination was not more effective on more complex substrates, these results generally support the idea that sex can accelerate adaptation to novel environments...
  43. ncbi request reprint The ecology and genetics of fitness in Chlamydomonas. IX. The rate of accumulation of variation of fitness under selection
    S Goho
    Department of Biology, McGill University, Montreal, Quebec, Canada
    Evolution 54:416-24. 2000
    ..Moreover, it suggests that chemostat populations may be more dynamic and more diverse than is usually thought...
  44. ncbi request reprint Global mapping of the yeast genetic interaction network
    Amy Hin Yan Tong
    Banting and Best Department of Medical Research, University of Toronto, Toronto, ON, Canada M5G 1L6
    Science 303:808-13. 2004
    ..Because digenic interactions are common in yeast, similar networks may underlie the complex genetics associated with inherited phenotypes in other organisms...
  45. pmc The spatial scale of genetic differentiation in a model organism: the wild yeast Saccharomyces paradoxus
    Vassiliki Koufopanou
    Division of Biology and NERC Centre for Population Biology, Imperial College London, Silwood Park, Ascot, Berks SL5 7PY, UK
    Philos Trans R Soc Lond B Biol Sci 361:1941-6. 2006
    ..Such replicated populations will be useful for studies in population genomics...
  46. ncbi request reprint Evolution of natural algal populations at elevated CO2
    Sinead Collins
    Ecol Lett 9:129-35. 2006
    ....
  47. pmc Functional studies of signaling pathways in peri-implantation development of the mouse embryo by RNAi
    Miguel L Soares
    The Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QR, UK
    BMC Dev Biol 5:28. 2005
    ..Here we report an efficient method for dsRNA-mediated gene silencing in late cleavage-stage mouse embryos that permits examination of phenotypes at post-implantation stages...