M A Behr
Affiliation: McGill University
- Comparative genomics of BCG vaccinesM A Behr
Montreal General Hospital, Montreal, Canada
Tuberculosis (Edinb) 81:165-8. 2001..The phenotypic relevance of these changes in BCG vaccines remains to be explored...
- Comparative genomics of BCG vaccines by whole-genome DNA microarrayM A Behr
Division of Infectious Diseases, Department of Medicine, McGill University Health Centre, Montreal H3G 1A4, Canada
Science 284:1520-3. 1999..A precise understanding of the genetic differences between closely related Mycobacteria suggests rational approaches to the design of improved diagnostics and vaccines...
- A point mutation in the mma3 gene is responsible for impaired methoxymycolic acid production in Mycobacterium bovis BCG strains obtained after 1927M A Behr
McGill University Health Centre, Montreal, Canada
J Bacteriol 182:3394-9. 2000..These findings indicate that a point mutation in mma3 occurred between 1927 and 1931, and that this mutant population became the dominant clone of BCG at the Pasteur Institute...
- Mycobacterium tuberculosis transmission over an 11-year period in a low-incidence, urban settingC Rossi
Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University Health Centre, Montreal, Quebec, Canada
Int J Tuberc Lung Dis 16:312-8. 2012..Montreal, Canada, has a mean annual tuberculosis (TB) incidence of 9 per 100,000 population, 1996-2007...
- Transmission of Mycobacterium tuberculosis from patients smear-negative for acid-fast bacilliM A Behr
Department of Medicine, McGill University Health Centre, Montreal, Quebec, Canada
Lancet 353:444-9. 1999..We aimed to estimate the risk of transmission from smear-negative individuals...
- Correlation between BCG genomics and protective efficacyM A Behr
Montreal General Hospital, Quebec, Canada
Scand J Infect Dis 33:249-52. 2001..The impact of these changes in the BCG genome on the protective efficacy observed in field trials remains to be determined...
- Use of simulated sputum specimens to estimate the specificity of laboratory-diagnosed tuberculosisA M Demers
Departement de Microbiologie et Immunologie, Centre hospitalier universitaire Sainte Justine, Universite de Montreal, Montreal, Quebec, Canada
Int J Tuberc Lung Dis 14:1016-23. 2010..Cross-contamination is not uncommon in mycobacteriology laboratories of high-income countries, as documented by bacterial genotyping. The extent of this problem in low-income countries is largely unknown, where this method is impractical...
- Rubella susceptibility predicts measles susceptibility: implications for postpartum immunizationM D Libman
Saint Mary s Hospital, Montreal, Quebec, Canada
Clin Infect Dis 31:1501-3. 2000..2% were also measles susceptible, whereas only 0.8% of the rubella-immune women were measles susceptible. Susceptibility to mumps was evenly divided between rubella-susceptible (7.8%) and rubella-immune (7.4%) groups...
- Global tuberculosis trends: a reflection of changes in tuberculosis control or in population health?O Oxlade
Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, McGill University, Montreal, Quebec, Canada
Int J Tuberc Lung Dis 13:1238-46. 2009..We have analyzed the association between changes in population health and health service indicators, and concomitant changes in TB incidence between 1990 and 2005...
- Use of geographic and genotyping tools to characterise tuberculosis transmission in MontrealI Haase
Department of Geography, McGill University, Montreal, Quebec, Canada
Int J Tuberc Lung Dis 11:632-8. 2007..In Canada, tuberculosis (TB) is increasingly an urban health problem. Montreal is Canada's second-largest city and the second most frequent destination for new immigrants and refugees...
- Divergence of immunologic and protective responses of different BCG strains in a murine modelR Kozak
Department of Medicine, McGill University Health Centre, Montreal, QC, H3G 1A4 Canada
Vaccine 29:1519-26. 2011..Together, our data demonstrated that the loss of RD2 resulted in decreased immunogenicity but did not affect protection against pulmonary TB, indicating a dissociation between these phenotypes associated with BCG vaccination...