Alan N Barkun

Summary

Affiliation: McGill University
Country: Canada

Publications

  1. pmc The Stretta procedure versus proton pump inhibitors and laparoscopic Nissen fundoplication in the management of gastroesophageal reflux disease: a cost-effectiveness analysis
    Dan Comay
    Division of Gastroenterology, McGill University Health Center, Montreal, Canada
    Can J Gastroenterol 22:552-8. 2008
  2. pmc A one-year economic evaluation of six alternative strategies in the management of uninvestigated upper gastrointestinal symptoms in Canadian primary care
    Alan N Barkun
    McGill University, Montreal, Quebec
    Can J Gastroenterol 24:489-98. 2010
  3. pmc Effectiveness of disseminating consensus management recommendations for ulcer bleeding: a cluster randomized trial
    Alan N Barkun
    McGill University Health Centre, McGill University, Montreal, Quebec
    CMAJ 185:E156-66. 2013
  4. doi request reprint Cost-effectiveness analysis: stress ulcer bleeding prophylaxis with proton pump inhibitors, H2 receptor antagonists
    Alan N Barkun
    Division of Gastroenterology, McGill University Health Center, McGill University, Montreal, Canada
    Value Health 16:14-22. 2013
  5. doi request reprint Proton pump inhibitors vs. histamine 2 receptor antagonists for stress-related mucosal bleeding prophylaxis in critically ill patients: a meta-analysis
    Alan N Barkun
    Division of Gastroenterology, McGill University Health Center, McGill University, Montreal, Quebec, Canada
    Am J Gastroenterol 107:507-20; quiz 521. 2012
  6. pmc The influence of demographic factors and health-related quality of life on treatment satisfaction in patients with gastroesophageal reflux disease treated with esomeprazole
    Alessio Degl' Innocenti
    AstraZeneca R and D, 431 83 Mölndal, Sweden
    Health Qual Life Outcomes 3:4. 2005
  7. pmc Pro/con debate: octreotide has an important role in the treatment of gastrointestinal bleeding of unknown origin?
    Yaseen Arabi
    Intensive Care Unit, King Abdulaziz Medical City, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh 11426, Saudi Arabia
    Crit Care 10:218. 2006
  8. pmc The impact of illness in patients with moderate to severe gastro-esophageal reflux disease
    Samer El-Dika
    Division of Gastroenterology, Veterans Affairs Medical Center, Salem, Virginia, USA
    BMC Gastroenterol 5:23. 2005
  9. doi request reprint Endoscopic hemostasis in peptic ulcer bleeding for patients with high-risk lesions: a series of meta-analyses
    Alan N Barkun
    Divisions of Gastroenterology, The McGill University Health Centre, Montreal General Hospital Site, Montreal, Quebec, Canada
    Gastrointest Endosc 69:786-99. 2009
  10. ncbi request reprint High-dose intravenous proton pump inhibition following endoscopic therapy in the acute management of patients with bleeding peptic ulcers in the USA and Canada: a cost-effectiveness analysis
    A N Barkun
    Division of Gastroenterology, McGill University, Montreal, Quebec, Canada
    Aliment Pharmacol Ther 19:591-600. 2004

Detail Information

Publications81

  1. pmc The Stretta procedure versus proton pump inhibitors and laparoscopic Nissen fundoplication in the management of gastroesophageal reflux disease: a cost-effectiveness analysis
    Dan Comay
    Division of Gastroenterology, McGill University Health Center, Montreal, Canada
    Can J Gastroenterol 22:552-8. 2008
    ..The Stretta procedure is an endoscopic therapy for gastroesophageal reflux disease...
  2. pmc A one-year economic evaluation of six alternative strategies in the management of uninvestigated upper gastrointestinal symptoms in Canadian primary care
    Alan N Barkun
    McGill University, Montreal, Quebec
    Can J Gastroenterol 24:489-98. 2010
    ..The cost-effectiveness of initial strategies in managing Canadian patients with uninvestigated upper gastrointestinalsymptoms remains controversial...
  3. pmc Effectiveness of disseminating consensus management recommendations for ulcer bleeding: a cluster randomized trial
    Alan N Barkun
    McGill University Health Centre, McGill University, Montreal, Quebec
    CMAJ 185:E156-66. 2013
    ..We sought to determine whether a national, multifaceted intervention could improve adherence to guidelines, especially for patients at high risk of nonvariceal upper gastrointestinal bleeding...
  4. doi request reprint Cost-effectiveness analysis: stress ulcer bleeding prophylaxis with proton pump inhibitors, H2 receptor antagonists
    Alan N Barkun
    Division of Gastroenterology, McGill University Health Center, McGill University, Montreal, Canada
    Value Health 16:14-22. 2013
    ..The literature also reports disparate rates of ventilator-assisted pneumonia (VAP) as side effects of these treatments. We compared the cost-effectiveness of these two prophylactic pharmacological options...
  5. doi request reprint Proton pump inhibitors vs. histamine 2 receptor antagonists for stress-related mucosal bleeding prophylaxis in critically ill patients: a meta-analysis
    Alan N Barkun
    Division of Gastroenterology, McGill University Health Center, McGill University, Montreal, Quebec, Canada
    Am J Gastroenterol 107:507-20; quiz 521. 2012
    ..The objective of this study was to evaluate the efficacy of PPIs vs. H2RAs in the prophylaxis of SRMB in critically ill adults with risk factors for bleeding...
  6. pmc The influence of demographic factors and health-related quality of life on treatment satisfaction in patients with gastroesophageal reflux disease treated with esomeprazole
    Alessio Degl' Innocenti
    AstraZeneca R and D, 431 83 Mölndal, Sweden
    Health Qual Life Outcomes 3:4. 2005
    ..The objective of this study was to assess correlates of treatment satisfaction in patients with GERD receiving a proton pump inhibitor, esomeprazole...
  7. pmc Pro/con debate: octreotide has an important role in the treatment of gastrointestinal bleeding of unknown origin?
    Yaseen Arabi
    Intensive Care Unit, King Abdulaziz Medical City, College of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh 11426, Saudi Arabia
    Crit Care 10:218. 2006
    ..In this issue of Critical Care, two expert teams debate the merits of using octreotide in non-variceal upper gastrointestinal bleeding...
  8. pmc The impact of illness in patients with moderate to severe gastro-esophageal reflux disease
    Samer El-Dika
    Division of Gastroenterology, Veterans Affairs Medical Center, Salem, Virginia, USA
    BMC Gastroenterol 5:23. 2005
    ..Gastro-esophageal reflux disease (GERD) is a common disease. It impairs health related quality of life (HRQL). However, the impact on utility scores and work productivity in patients with moderate to severe GERD is not well known...
  9. doi request reprint Endoscopic hemostasis in peptic ulcer bleeding for patients with high-risk lesions: a series of meta-analyses
    Alan N Barkun
    Divisions of Gastroenterology, The McGill University Health Centre, Montreal General Hospital Site, Montreal, Quebec, Canada
    Gastrointest Endosc 69:786-99. 2009
    ..Optimal endoscopic hemostasis remains undetermined. This was a systematic review of contemporary methods of endoscopic hemostasis for patients with bleeding ulcers that exhibited high-risk stigmata...
  10. ncbi request reprint High-dose intravenous proton pump inhibition following endoscopic therapy in the acute management of patients with bleeding peptic ulcers in the USA and Canada: a cost-effectiveness analysis
    A N Barkun
    Division of Gastroenterology, McGill University, Montreal, Quebec, Canada
    Aliment Pharmacol Ther 19:591-600. 2004
    ..The efficacy of high-dose intravenous proton pump inhibition has recently been shown, yet its cost-effectiveness remains poorly studied...
  11. doi request reprint Cost effectiveness of high-dose intravenous esomeprazole for peptic ulcer bleeding
    Alan N Barkun
    Division of Gastroenterology, McGill University Health Centre, Montreal General Hospital, Montreal, Quebec, Canada
    Pharmacoeconomics 28:217-30. 2010
    ..Whereas, in the Spanish setting, the high-dose IV esomeprazole strategy appeared dominant, being more effective and less costly...
  12. doi request reprint Systematic review of the symptom burden, quality of life impairment and costs associated with peptic ulcer disease
    Alan Barkun
    Division of Gastroenterology, McGill University, Montreal, Quebec, Canada
    Am J Med 123:358-66.e2. 2010
    ..However, the widespread use of nonsteroidal anti-inflammatory drugs and low-dose acetylsalicylic acid means that the burden of peptic ulcer disease remains a relevant issue...
  13. ncbi request reprint The cost-effectiveness of high-dose oral proton pump inhibition after endoscopy in the acute treatment of peptic ulcer bleeding
    A N Barkun
    Division of Gastroenterology, McGill University Health Centre, Montreal General Hospital Site, Quebec, Canada
    Aliment Pharmacol Ther 20:195-202. 2004
    ..Recent data suggest a role for high-dose oral proton pump inhibition in ulcer bleeding...
  14. ncbi request reprint A Canadian clinical practice algorithm for the management of patients with nonvariceal upper gastrointestinal bleeding
    Alan Barkun
    Department of Medicine, McGill University, Montreal, Quebec, Canada
    Can J Gastroenterol 18:605-9. 2004
    ..To use current evidence-based recommendations to provide a user-friendly clinical algorithm for the management of upper gastrointestinal bleeding, adapted to the Canadian environment...
  15. doi request reprint International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding
    Alan N Barkun
    Division of Gastroenterology, Montreal General Hospital Site, McGill University Health Centre, Montreal, Quebec, Canada
    Ann Intern Med 152:101-13. 2010
    ..A multidisciplinary group of 34 experts from 15 countries developed this update and expansion of the recommendations on the management of acute nonvariceal upper gastrointestinal bleeding (UGIB) from 2003...
  16. doi request reprint Cost-effectiveness of proton-pump inhibition before endoscopy in upper gastrointestinal bleeding
    Salman Al-Sabah
    Division of General Surgery, McGill University, Montreal, Quebec, Canada
    Clin Gastroenterol Hepatol 6:418-25. 2008
    ..Randomized trials suggest high-dose proton-pump inhibitors (PPIs) administered before gastroscopy in suspected upper gastrointestinal bleeding downstage bleeding ulcer stigmata. We assessed the cost-effectiveness of this approach...
  17. ncbi request reprint Do proton-pump inhibitors confer additional gastrointestinal protection in patients given celecoxib?
    Elham Rahme
    McGill University, Research Institute of McGill University Health Center, Montreal, Canada
    Arthritis Rheum 57:748-55. 2007
    ..We assessed the association between GI hospitalizations and use of celecoxib with a PPI versus celecoxib alone, and NS-NSAIDs with a PPI or NS-NSAIDs alone in elderly patients...
  18. ncbi request reprint Effect of chronic intake of NSAIDs and cyclooxygenase 2-selective inhibitors on esophageal cancer incidence
    Marc Bardou
    Division of Gastroenterology, Department of Medicine, McGill University and McGill University Health Center, Montreal, Quebec, Canada
    Clin Gastroenterol Hepatol 2:880-7. 2004
    ..We investigated the effects of the selective cyclooxygenase 2 inhibitors (coxibs), rofecoxib and celecoxib, the nonselective nonsteroidal anti-inflammatory drugs (NSAIDs), and aspirin on esophageal cancer...
  19. pmc Endoscopist specialty is associated with colonoscopy quality
    Mengzhu Jiang
    Division of Clinical Epidemiology, Research Institute of the McGill University Health Centre, 687 Pine Avenue West, V Building, Room V2 15, Montreal, QC H3A 1A1, Canada
    BMC Gastroenterol 13:78. 2013
    ..We sought to examine the relationship between endoscopist specialty and polypectomy rate, a colonoscopy quality indicator. Polypectomy rate is defined as the proportion of colonoscopies that result in the removal of one or more polyps...
  20. ncbi request reprint Predictors of early rebleeding after endoscopic therapy in patients with nonvariceal upper gastrointestinal bleeding secondary to high-risk lesions
    Davide Maggio
    Department of Medicine, McGill University Health Centre, McGill University, Montreal, Quebec, Canada
    Can J Gastroenterol 27:454-8. 2013
    ....
  21. pmc Different screening definitions have little impact on polypectomy rate estimates
    Mengzhu Jiang
    Division of Clinical Epidemiology, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada
    Can J Gastroenterol 26:791-4. 2012
    ..Polypectomy rate is a surrogate quality indicator for screening colonoscopy. Various methods for identifying screening colonoscopies have been used and it is unclear how different definitions affect the estimated polypectomy rate...
  22. pmc Does blood urea nitrogen level predict severity and high-risk endoscopic lesions in patients with nonvariceal upper gastrointestinal bleeding?
    Khalid Al-Naamani
    Division of Gastroenterology, McGill University Health Centre, Montreal, Canada
    Can J Gastroenterol 22:399-403. 2008
    ..There are little or no data correlating sole blood urea nitrogen (BUN) level with the severity of nonvariceal UGIB or the presence of HRLs in the adult population...
  23. ncbi request reprint Validation of the Rockall scoring system for outcomes from non-variceal upper gastrointestinal bleeding in a Canadian setting
    Robert A Enns
    Division of Gastroenterology, Department of Medicine, St Paul s Hospital, University of British Columbia, 300 1144 Burrard Street, Vancouver, BC, V6Z 2A5, Canada
    World J Gastroenterol 12:7779-85. 2006
    ..To validate the Rockall scoring system for predicting outcomes of rebleeding, and the need for a surgical procedure and death...
  24. ncbi request reprint The importance of process issues as predictors of time to endoscopy in patients with acute upper-GI bleeding using the RUGBE data
    Eduardo B da Silveira
    Division of Gastroenterology, McGill University Health Centre, McGill University, Montreal, Quebec, Canada
    Gastrointest Endosc 64:299-309. 2006
    ..However, there is little information regarding clinical and process determinants that affect the time from onset of bleeding to performance of the endoscopy...
  25. ncbi request reprint A sampling of Canadian practice in managing nonvariceal upper gastrointestinal bleeding before recent guideline publication: is there room for improvement?
    Karen Bensoussan
    McGill University, Royal Victoria Hospital, Montreal, Canada
    Can J Gastroenterol 19:487-95. 2005
    ..There are few recent published consensus guidelines regarding nonvariceal upper gastrointestinal bleeding. In 2003, the Canadian Association of Gastroenterology sponsored a set of 20 recommendations...
  26. doi request reprint Is routine second-look endoscopy effective after endoscopic hemostasis in acute peptic ulcer bleeding? A meta-analysis
    Sara El Ouali
    Division of Gastroenterology, McGill University Health Center, McGill University, Montreal, Quebec, Canada
    Gastrointest Endosc 76:283-92. 2012
    ..Routine second-look endoscopy in modern-era peptic ulcer bleeding (PUB) remains controversial...
  27. pmc Report on the expert forum on using information technology to facilitate uptake and impact of colorectal cancer screening guidelines
    Maida J Sewitch
    Department of Medicine, McGill University, Montreal, Quebec
    Can J Gastroenterol 26:902-4. 2012
    ....
  28. pmc Rate of serious complications of colonoscopy in Quebec
    Maida J Sewitch
    Department of Medicine, McGill University, Montreal, Quebec
    Can J Gastroenterol 26:611-3. 2012
    ..The rate of serious complications is one marker of the quality of colonoscopy services...
  29. doi request reprint Prokinetics in acute upper GI bleeding: a meta-analysis
    Alan N Barkun
    Division of Gastroenterology, McGill University Health Center, McGill University, Montreal, Quebec, Canada
    Gastrointest Endosc 72:1138-45. 2010
    ..Recent data suggest that administration of prokinetics before gastroscopy may be useful in patients with acute upper GI bleeding (UGIB). Published studies are limited in the number of subjects evaluated, and the conclusions are disparate...
  30. doi request reprint Non-variceal upper GI bleeding in patients already hospitalized for another condition
    Tanja Müller
    Division of Gastroenterology, The Montreal General Hospital Site, McGill University Health Centre, McGill University, Montreal, Canada
    Am J Gastroenterol 104:330-9. 2009
    ....
  31. ncbi request reprint Treatment costs to prevent or treat upper gastrointestinal adverse events associated with NSAIDs
    Elham Rahme
    Department of Medicine, McGill University and Research Institute, McGill University Health Center, Montreal, Quebec, Canada
    Drug Saf 27:1019-42. 2004
    ..Thus, from an economic perspective, the healthcare system would benefit from treating patients at risk of NSAID gastropathy with COX-2 inhibitors, but not those at no to low risk...
  32. ncbi request reprint The cyclooxygenase-2-selective inhibitors rofecoxib and celecoxib prevent colorectal neoplasia occurrence and recurrence
    Elham Rahme
    Division of Clinical Epidemiology, Montreal General Hospital, 1650 Cedar Avenue, Montreal, Quebec H3G 1A4, Canada
    Gastroenterology 125:404-12. 2003
    ....
  33. pmc Patient-identified quality indicators for colonoscopy services
    Maida J Sewitch
    Department of Medicine, McGill University, Montreal, Quebec
    Can J Gastroenterol 27:25-32. 2013
    ..However, there are no studies that have investigated patient expectations and/or perceptions of quality indicators in endoscopy services...
  34. doi request reprint Conflicts of interest ethics: silencing expertise in the development of international clinical practice guidelines
    Derek J Jones
    Division of Gastroenterology, Montreal General Hospital Site, McGill University Health Centre, Montreal, Quebec, Canada
    Ann Intern Med 156:809-16, W-283. 2012
    ..Optimal management of FCOIs to ensure independent, expert CPGs remains ethically contested...
  35. ncbi request reprint Heartburn-dominant, uninvestigated dyspepsia: a comparison of 'PPI-start' and 'H2-RA-start' management strategies in primary care--the CADET-HR Study
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Ontario, Canada
    Aliment Pharmacol Ther 21:1189-202. 2005
    ..There are few data on empiric, stepped therapy for heartburn relief or subsequent relapse in primary care...
  36. ncbi request reprint Use of gastric acid-suppressive agents and the risk of community-acquired Clostridium difficile-associated disease
    Sandra Dial
    Division of Critical Care and Respiratory and Clinical Research, Department of Epidemiology and Biostatistics, McGill University, Montreal, Quebec
    JAMA 294:2989-95. 2005
    ..Recent reports suggest an increasing occurrence and severity of Clostridium difficile-associated disease. We assessed whether the use of gastric acid-suppressive agents is associated with an increased risk in the community...
  37. pmc Endoscopy reporting standards
    Daphnée Beaulieu
    Division of Gastroenterology, McGill University Health Centre, McGill University, Montreal, Quebec, Canada
    Can J Gastroenterol 27:286-92. 2013
    ..The present article focuses specifically on the identification of key elements that should be found in all electronic endoscopy reports detailing recommendations adopted by the CAG consensus group...
  38. pmc The costs of colonoscopy in a Canadian hospital using a microcosting approach
    Nour Sharara
    Division of Gastroenterology, McGill University, Montreal, Quebec
    Can J Gastroenterol 22:565-70. 2008
    ..Colonoscopy has become accepted as one of the most effective methods of screening patients for colorectal cancer, and is used to remove the majority of colonic adenomas...
  39. doi request reprint No benefit of covered vs uncovered self-expandable metal stents in patients with malignant distal biliary obstruction: a meta-analysis
    Majid A Almadi
    Division of Gastroenterology, McGill University Health Centre, Montreal General Hospital, McGill University, Montreal, QC, Canada
    Clin Gastroenterol Hepatol 11:27-37.e1. 2013
    ..These studies compared patency of uncovered SEMS and covered SEMS, along with rates of pancreatitis, cholecystitis, cholangitis, SEMS migration, bleeding, perforation, and recurrent biliary obstruction...
  40. pmc Canadian credentialing guidelines for esophagogastroduodenoscopy
    Terry Ponich
    Division of Gastroenterology, University of Western Ontario, London, Canada
    Can J Gastroenterol 22:349-54. 2008
  41. pmc The potential impact of contemporary developments in the management of patients with gastroesophageal reflux disease undergoing an initial gastroscopy
    Suhail B Salem
    Department of Pathology, McGill University Health Centre, McGill University, and Montreal General Hospital Site, Montreal, Quebec, Canada
    Can J Gastroenterol 23:99-104. 2009
    ..There is also increasing recognition of eosinophilic esophagitis (EE) in patients with GERD-like symptoms...
  42. ncbi request reprint The elective evaluation of patients with suspected choledocholithiasis undergoing laparoscopic cholecystectomy
    Frances Tse
    Divisions of Gastroenterology and General Surgery, Montreal General Hospital and Royal Victoria Hospital Sites, McGill University Health Centre, 1650 Cedar Avenue, Montreal, Quebec, Canada H3G 1A4
    Gastrointest Endosc 60:437-48. 2004
  43. ncbi request reprint Nasogastric aspirate predicts high-risk endoscopic lesions in patients with acute upper-GI bleeding
    Abdulrahman M Aljebreen
    Division of Gastroenterology, University of Calgary, Calgary, AB, Canada
    Gastrointest Endosc 59:172-8. 2004
    ..The aim of this study is to determine whether nasogastric aspirate predicts the presence of high-risk lesions...
  44. ncbi request reprint There is no difference in the disease severity of gastro-oesophageal reflux disease between patients infected and not infected with Helicobacter pylori
    C A Fallone
    Division of Gastroenterology, McGill University Health Center, Montreal, Quebec, Canada
    Aliment Pharmacol Ther 20:761-8. 2004
    ..The role of Helicobacter pylori in gastro-oesophageal reflux disease (GERD) is controversial...
  45. ncbi request reprint Utility of serology in determining Helicobacter pylori eradication after therapy
    C A Fallone
    Division of Gastroenterology, Royal Victoria Hospital, Montreal, Quebec
    Can J Gastroenterol 12:117-24. 1998
    ..To determine the usefulness of four serological tests in confirming cure of H pylori infection before the previously reported six-month post-treatment delay...
  46. ncbi request reprint Helicobacter DNA in bile: correlation with hepato-biliary diseases
    C A Fallone
    Department of Medicine, McGill University Health Centre, McGill University, West Montreal, Quebec, Canada
    Aliment Pharmacol Ther 17:453-8. 2003
    ..Helicobacter has been identified in isolated cases of hepato-biliary diseases, but its role in the pathogenesis of these conditions remains unclear...
  47. ncbi request reprint Predictors of failure of Helicobacter pylori eradication and predictors of ulcer recurrence: a randomized controlled trial
    C A Fallone
    Division of Gastroenterology, McGill University Health Centre, Montreal, Que
    Clin Invest Med 22:185-94. 1999
    ..In light of evidence that Helicobacter pylori treatment fails 5% to 20% of the time, the objective of this study was to determine predictors of unsuccessful H. pylori eradication and of duodenal ulcer recurrence...
  48. ncbi request reprint A review of the possible bacterial determinants of clinical outcome in Helicobacter pylori infection
    C A Fallone
    Division of Gastroenterology, Royal Victoria Hospital, McGill University, Montreal, QC, Canada
    Can J Microbiol 44:201-10. 1998
    ..The determination of the relative importance of each of these recognized and other as yet unrecognized factors responsible for disease outcome will assist in the appropriate targeting of patients in the treatment of H. pylori infection...
  49. ncbi request reprint Hospitalization for gastrointestinal bleeding associated with non-steroidal anti-inflammatory drugs among elderly patients using low-dose aspirin: a retrospective cohort study
    E Rahme
    Division of Clinical Epidemiology, Montreal General Hospital L10 408, 1650 Cedar Ave, Montreal, Quebec H3G 1A4, Canada
    Rheumatology (Oxford) 46:265-72. 2007
    ..It is unclear, however, whether this fact holds good among patients taking ASA. We compared GI hospitalization rates among elderly patients taking celecoxib, NS-NSAIDs, celecoxib and ASA or NS-NSAIDs and ASA...
  50. ncbi request reprint Unexplained chronic cough: to test for or to treat GERD--do we have the answer?
    C A Fallone
    Division of Gastroenterology, McGill University Health Center, Montreal, Que, Canada
    Dig Liver Dis 38:458-60. 2006
  51. ncbi request reprint Do physicians correctly assess patient symptom severity in gastro-oesophageal reflux disease?
    C A Fallone
    Division of Gastroenterology, McGill University Health Center, Montreal, QC, Canada
    Aliment Pharmacol Ther 20:1161-9. 2004
    ..The accuracy of physicians' assessment of the severity of gastro-oesophageal reflux disease is unclear...
  52. ncbi request reprint The treatment of peptic esophageal strictures
    A N Barkun
    Fonds de la Recherche en Santé du Québec, Montreal
    Can J Gastroenterol 11:94B-97B. 1997
    ..At this time, well designed prospective comparative trials are needed to quantify better the cost effectiveness of available treatment strategies in the management of patients with esophageal peptic strictures...
  53. ncbi request reprint The prevalence of Barrett's oesophagus in a cohort of 1040 Canadian primary care patients with uninvestigated dyspepsia undergoing prompt endoscopy
    S J O Veldhuyzen van Zanten
    Division of Gastroenterology, Dalhousie University, Halifax, NS, Canada
    Aliment Pharmacol Ther 23:595-9. 2006
    ..The prevalence of Barrett's oesophagus in patients undergoing gastroscopy may be influenced by possible referral bias...
  54. pmc Current status of core and advanced adult gastrointestinal endoscopy training in Canada: Survey of existing accredited programs
    Xin Xiong
    Division of Gastroenterology, McGill University Health Centre, McGill University, Montreal, Quebec, Canada
    Can J Gastroenterol 27:267-72. 2013
    ..To determine the current status of core and advanced adult gastroenterology training in Canada...
  55. pmc Feasibility of a call-in centre to deliver colorectal cancer screening in primary care
    Maida J Sewitch
    McGill University, Medicine, 687 Pine Ave W, V Building, Montreal, QC H3A 1A1
    Can Fam Physician 59:e550-7. 2013
    ..To evaluate the feasibility of a call-in centre to deliver colorectal cancer (CRC) screening in primary care through self-administered fecal occult blood testing (FOBT)...
  56. pmc Disparities in outcomes following admission for cholangitis
    Julia McNabb-Baltar
    Division of Gastroenterology, McGill University, Montreal, Canada
    PLoS ONE 8:e59487. 2013
    ..The objective of this study was to examine factors associated with in-hospital mortality, prolonged length of stay (LOS) and increased hospital charges (HC) in patients presenting with acute cholangitis...
  57. ncbi request reprint The role of ciprofloxacin in prolonging polyethylene biliary stent patency: a multicenter, double-blinded effectiveness study
    Gabriel Chan
    Department of Clinical Epidemiology, McGill University, Montreal, Canada
    J Gastrointest Surg 9:481-8. 2005
    ..The observed trends suggest that ciprofloxacin significantly decreases the incidence of cholangitis and results in improvements in certain aspects of quality of life...
  58. doi request reprint EUS: a meta-analysis of test performance in suspected choledocholithiasis
    Frances Tse
    Division of Gastroenterology, McMaster University Medical Centre, McMaster University, Hamilton, Ontario, Canada
    Gastrointest Endosc 67:235-44. 2008
    ..The literature pertaining to EUS for the diagnosis of choledocholithiasis reports widely varying sensitivities and specificities...
  59. pmc A prospective intervention study of colonoscopy reporting among patients screened or surveilled for colorectal neoplasia
    Daphnée Beaulieu
    McGill University Health Centre, Montreal, Quebec
    Can J Gastroenterol 26:718-22. 2012
    ..The impact of modifying electronic colonoscopy reporting software for improving adherence to guidelines regarding quality standards documentation remains poorly characterized...
  60. ncbi request reprint Assessing clinical generalizability in sedation studies of upper GI endoscopy
    Neena S Abraham
    Division of Gastroenterology, McGill University, Health Centre, Montreal, Quebec
    Gastrointest Endosc 60:28-33. 2004
    ..The objectives of this study were to determine the characteristics of patients who refused inclusion in a randomized controlled trial of sedation and to compare these characteristics to those of patients who agreed to participate...
  61. ncbi request reprint Validation of a 7-point Global Overall Symptom scale to measure the severity of dyspepsia symptoms in clinical trials
    S J O Veldhuyzen van Zanten
    Division of Gastroenterology, Dalhousie University, Halifax, NS, Canada
    Aliment Pharmacol Ther 23:521-9. 2006
    ..Currently there is no consensus on the optimal method to measure the severity of dyspepsia symptoms in clinical trials...
  62. ncbi request reprint Meta-analysis: proton-pump inhibition in high-risk patients with acute peptic ulcer bleeding
    M Bardou
    Division of Gastroenterology, The McGill University Health Centre, Montreal General Hospital Site, Montreal, Quebec H3G 1A4, Canada
    Aliment Pharmacol Ther 21:677-86. 2005
    ..Recent data suggest that profound acid suppression may improve outcomes of patients in peptic ulcer bleeding...
  63. ncbi request reprint The role of intravenous proton pump inhibitors in the modern management of nonvariceal upper gastrointestinal bleeding
    A N Barkun
    Division of Gastroenterology, McGill University, Montreal, Quebec, Canada
    Drugs Today (Barc) 39:3-10. 2003
    ..However, the optimum dose, timing of administration and subgroups of patients who will benefit most from such treatment need to be further characterized...
  64. ncbi request reprint Prolonged treatment duration is required for successful Helicobacter pylori eradication with proton pump inhibitor triple therapy in Canada
    Carlo A Fallone
    Division of McGill University Health Centre, McGill University, Montreal, Quebec, Canada
    Can J Gastroenterol 27:397-402. 2013
    ..Prolonging therapy may be associated with poorer compliance and, hence, may not have a better outcome in a real-world setting...
  65. pmc Accuracy of administrative claims data for polypectomy
    Jonathan M Wyse
    Division of Gastroenterology, Department of Medicine, Jewish General Hospital, McGill University, Montreal, Canada
    CMAJ 183:E743-7. 2011
    ..We determined the level of agreement between physician claims for polypectomy and documentation of the procedure in endoscopy reports...
  66. ncbi request reprint Recommendations for the appropriate use of anti-inflammatory drugs in the era of the coxibs: defining the role of gastroprotective agents
    Richard H Hunt
    Division of Gastroenterology, Department of Medicine, McMaster University Medical Centre, Hamilton, Ontario
    Can J Gastroenterol 16:231-40. 2002
    ..Patients at high risk require a GPA in addition to a coxib...
  67. ncbi request reprint Predictors of inappropriate utilization of intravenous proton pump inhibitors
    W Afif
    Division of Gastroenterology, McGill University, Montreal, Quebec, Canada
    Aliment Pharmacol Ther 25:609-15. 2007
    ..Inappropriate use of intravenous proton pump inhibitors is prevalent...
  68. pmc Canadian credentialing guidelines for endoscopic privileges: an overview
    D Armstrong
    Division of Gastroenterology, McMaster University, Hamilton, Canada
    Can J Gastroenterol 21:797-801. 2007
  69. doi request reprint Platelet transfusion threshold in patients with upper gastrointestinal bleeding: a systematic review
    Anoush Razzaghi
    Department of Medicine, McGill University, Montreal, Quebec, Canada
    J Clin Gastroenterol 46:482-6. 2012
    ..GOALS AND STUDY: A systematic review was carried out to determine the optimal approach when managing patients with thrombocytopenia in the setting of nonvariceal upper GI bleeding...
  70. ncbi request reprint Diagnosis and management of cholecystitis and cholangitis
    Ian F Yusoff
    McGill University Health Centre, 1650 Cedar Avenue, Montreal, Quebec H3G 1A4, Canada
    Gastroenterol Clin North Am 32:1145-68. 2003
    ..Effective and optimal management of biliary tract emergencies relies on close cooperation between gastroenterologist, surgeon, and radiologist...
  71. ncbi request reprint Expandable metal biliary stenting in patients with recurrent premature polyethylene stent occlusion
    K Menon
    Division of Gastroenterology, McGill University and the McGill University Health Centre, Montreal, Quebec, Canada
    Am J Gastroenterol 96:1435-40. 2001
    ..However the duration of patency still seems to be significantly longer than that of the most recently placed plastic stent...
  72. ncbi request reprint The safety of endoscopic sphincterotomy in patients receiving antiplatelet agents: a case-control study
    N Hussain
    Division of Gastroenterology, McGill University, Montreal, Quebec, Canada
    Aliment Pharmacol Ther 25:579-84. 2007
    ..To determine whether antiplatelet agents are associated with endoscopic sphincterotomy-related haemorrhage as few well-controlled data exist on this controversial issue...
  73. ncbi request reprint Patient satisfaction after MRCP and ERCP
    K Menon
    Department of Diagnostic Radiology, McGill University and the McGill University Health Centre, Montreal, Quebec, Canada
    Am J Gastroenterol 96:2646-50. 2001
    ..Patient satisfaction may be further improved by reducing noise and claustrophobia with selective premedication, earplugs, and the use of the new quieter fenestrated magnetic resonance imaging scanners...
  74. ncbi request reprint The Quebec Association of Gastroenterology position paper on colorectal cancer screening - 2003
    A N Barkun
    MUHC McGill University and the McGill University Health Centre, Montreal General Hospital Site, Montreal, Canada
    Can J Gastroenterol 18:509-19. 2004
    ..The program should be evaluated; specific billing codes for screening for colorectal cancer would help facilitate this. Formal feasibility, effectiveness and cost-effectiveness studies in Quebec are now warranted...
  75. ncbi request reprint The prevalence of clinically significant endoscopic findings in primary care patients with uninvestigated dyspepsia: the Canadian Adult Dyspepsia Empiric Treatment - Prompt Endoscopy (CADET-PE) study
    A B R Thomson
    University of Alberta, Edmonton, Alberta, Canada
    Aliment Pharmacol Ther 17:1481-91. 2003
    ..Uninvestigated dyspepsia is common in family practice. The prevalence of clinically significant upper gastrointestinal findings (CSFs) in adult uninvestigated dyspepsia patients, and their predictability based on history, is unknown...
  76. ncbi request reprint Review article: acid-related disease--what are the unmet clinical needs?
    P O Katz
    Division of Gastroenterology, Albert Einstein Medical Center, Philadelphia, PA 19141, USA
    Aliment Pharmacol Ther 23:9-22. 2006
    ..Finally, therapy that could be administered without regard to time of day and/or food intake would offer dosing flexibility and thus have a positive effect on patients' compliance...
  77. ncbi request reprint Should every patient with suspected upper GI bleeding receive a proton pump inhibitor while awaiting endoscopy?
    A N Barkun
    Gastrointest Endosc 67:1064-6. 2008
  78. ncbi request reprint Validation of a symptom diary for patients with gastro-oesophageal reflux disease
    M A Puhan
    Horten Centre, University of Zurich, Switzerland
    Aliment Pharmacol Ther 23:531-41. 2006
    ..We assessed the validity and responsiveness of a symptom diary for patients with gastro-oesophageal reflux disease...
  79. pmc Canadian credentialing guidelines for colonoscopy
    J Romagnuolo
    Division of Gastronenterrology and Hepatology, Medical University of South Carolina, Charleston, SC, USA
    Can J Gastroenterol 22:17-22. 2008
  80. ncbi request reprint EUS-first versus ERC-first for patients with intermediate probability of bile duct stones: is one strategy superior to the other?
    E B da Silveira
    Endoscopy 39:357-8. 2007
  81. pmc Canadian credentialing guidelines for flexible sigmoidoscopy
    R Enns
    University of British Columbia, Vancouver, Canada
    Can J Gastroenterol 22:115-9. 2008