Bernard Le Foll

Summary

Country: Canada

Publications

  1. ncbi request reprint Peroxisome proliferator-activated receptor (PPAR) agonists as promising new medications for drug addiction: preclinical evidence
    Bernard Le Foll
    Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Curr Drug Targets 14:768-76. 2013
  2. doi request reprint Cannabis and Δ9-tetrahydrocannabinol (THC) for weight loss?
    Bernard Le Foll
    Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health CAMH, Toronto, Ontario, Canada
    Med Hypotheses 80:564-7. 2013
  3. pmc Varenicline decreases nicotine self-administration and cue-induced reinstatement of nicotine-seeking behaviour in rats when a long pretreatment time is used
    Bernard Le Foll
    Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, Canada
    Int J Neuropsychopharmacol 15:1265-74. 2012
  4. doi request reprint Cannabis use and mental health-related quality of life among individuals with anxiety disorders
    Shaul Lev-Ran
    Social Aetiology of Mental Illness SAMI CIHR Training Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    J Anxiety Disord 26:799-810. 2012
  5. doi request reprint Self-reported psychotic disorders among Individuals with substance use disorders: findings from the National Epidemiologic Survey on Alcohol and Related Conditions
    Shaul Lev-Ran
    Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Am J Addict 21:531-5. 2012
  6. pmc Nicotine-taking and nicotine-seeking in C57Bl/6J mice without prior operant training or food restriction
    Yijin Yan
    Translational Addiction Research Laboratory, Neuroscience Department, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Behav Brain Res 230:34-9. 2012
  7. pmc Effects of a selective cannabinoid CB2 agonist and antagonist on intravenous nicotine self administration and reinstatement of nicotine seeking
    Islam Gamaleddin
    Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, Canada
    PLoS ONE 7:e29900. 2012
  8. doi request reprint Gender differences in prevalence of substance use disorders among individuals with lifetime exposure to substances: results from a large representative sample
    Shaul Lev-Ran
    Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Am J Addict 22:7-13. 2013
  9. doi request reprint Cannabinoid receptor stimulation increases motivation for nicotine and nicotine seeking
    Islam Gamaleddin
    Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Canada
    Addict Biol 17:47-61. 2012
  10. ncbi request reprint Pharmacotherapy of alcohol use disorders and concurrent psychiatric disorders: a review
    Shaul Lev-Ran
    Addiction Psychiatry Fellow, Translational Addiction Research Laboratory, Addictions Program, Centre for Addiction and Mental Health, Toronto, Ontario Social Aetiology of Mental Illness SAMI Canadian Institutes of Health Research Fellow, Centre for Addiction and Mental Health, Toronto, Ontario
    Can J Psychiatry 57:342-9. 2012

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Peroxisome proliferator-activated receptor (PPAR) agonists as promising new medications for drug addiction: preclinical evidence
    Bernard Le Foll
    Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Curr Drug Targets 14:768-76. 2013
    ..Finally, studies that investigated the effects of PPAR agonists on neural pathways of addiction are reviewed. Taken together these preclinical data indicate that PPAR agonists are promising new medications for drug addiction treatment...
  2. doi request reprint Cannabis and Δ9-tetrahydrocannabinol (THC) for weight loss?
    Bernard Le Foll
    Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health CAMH, Toronto, Ontario, Canada
    Med Hypotheses 80:564-7. 2013
    ..We therefore propose the seemingly paradoxical hypothesis that THC or a THC/cannabidiol combination drug may produce weight loss and may be a useful therapeutic for the treatment of obesity and its complications...
  3. pmc Varenicline decreases nicotine self-administration and cue-induced reinstatement of nicotine-seeking behaviour in rats when a long pretreatment time is used
    Bernard Le Foll
    Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, Canada
    Int J Neuropsychopharmacol 15:1265-74. 2012
    ..The ability of varenicline to reduce both nicotine-taking and nicotine-seeking behaviour can contribute to its relatively high efficacy in treating human smokers...
  4. doi request reprint Cannabis use and mental health-related quality of life among individuals with anxiety disorders
    Shaul Lev-Ran
    Social Aetiology of Mental Illness SAMI CIHR Training Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    J Anxiety Disord 26:799-810. 2012
    ..Out results highlight the importance of taking into account direct functional and emotional outcomes, as well as frequency of cannabis used, when assessing the impact of cannabis use among individuals with anxiety disorders...
  5. doi request reprint Self-reported psychotic disorders among Individuals with substance use disorders: findings from the National Epidemiologic Survey on Alcohol and Related Conditions
    Shaul Lev-Ran
    Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Am J Addict 21:531-5. 2012
    ..Most reports to-date focus on the prevalence of SUDs among clinical populations of patients with PDs, and there is a lack of data pertaining to rates of PDs among individuals with substance use and SUDs...
  6. pmc Nicotine-taking and nicotine-seeking in C57Bl/6J mice without prior operant training or food restriction
    Yijin Yan
    Translational Addiction Research Laboratory, Neuroscience Department, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Behav Brain Res 230:34-9. 2012
    ..Future work will utilize these models to evaluate nicotine-taking and relapsing behavior in genetically-altered mice...
  7. pmc Effects of a selective cannabinoid CB2 agonist and antagonist on intravenous nicotine self administration and reinstatement of nicotine seeking
    Islam Gamaleddin
    Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, Canada
    PLoS ONE 7:e29900. 2012
    ..Administration of the CB2 ligands did not affect either nicotine-taking nicotine-seeking behavior. Our results do not support the involvement of CB2 receptors in nicotine-taking or nicotine-seeking behavior...
  8. doi request reprint Gender differences in prevalence of substance use disorders among individuals with lifetime exposure to substances: results from a large representative sample
    Shaul Lev-Ran
    Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Am J Addict 22:7-13. 2013
    ..In this study, we explored gender differences in prevalence of SUDs among individuals with lifetime exposure to substances using a single diagnostic category (abuse or dependence)...
  9. doi request reprint Cannabinoid receptor stimulation increases motivation for nicotine and nicotine seeking
    Islam Gamaleddin
    Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Canada
    Addict Biol 17:47-61. 2012
    ..Thus, modulating CB1-receptor signalling might have therapeutic value for treating nicotine dependence...
  10. ncbi request reprint Pharmacotherapy of alcohol use disorders and concurrent psychiatric disorders: a review
    Shaul Lev-Ran
    Addiction Psychiatry Fellow, Translational Addiction Research Laboratory, Addictions Program, Centre for Addiction and Mental Health, Toronto, Ontario Social Aetiology of Mental Illness SAMI Canadian Institutes of Health Research Fellow, Centre for Addiction and Mental Health, Toronto, Ontario
    Can J Psychiatry 57:342-9. 2012
    ..Several prevalent psychiatric disorders have not been studied when co-occurring with AUDs. Further research of pharmacological treatments for concurrent AUDs and psychiatric diagnoses is urgently needed...
  11. doi request reprint Cannabis use and cannabis use disorders among individuals with mental illness
    Shaul Lev-Ran
    Social Aetiology of Mental Illness SAMI CIHR Training Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada Social and Epidemiological Research Department, Centre for Addiction and Mental Health, Toronto, Ontario, Canada Addictions Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada Addiction Medicine Services, Department of Psychiatry, Sheba Medical Center, Tel Hashomer, Israel Electronic address
    Compr Psychiatry 54:589-98. 2013
    ..However, this subject has not been sufficiently investigated, particularly given limitations in diagnostic tools used and lack of data pertaining to frequency of cannabis used...
  12. doi request reprint Exploring the association between lifetime prevalence of mental illness and transition from substance use to substance use disorders: results from the National Epidemiologic Survey of Alcohol and Related Conditions (NESARC)
    Shaul Lev-Ran
    Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Am J Addict 22:93-8. 2013
    ..This may be important as increased prevalence of substance use among individuals with MI may partially explain the strong association between SUDs and MI...
  13. doi request reprint AM404 attenuates reinstatement of nicotine seeking induced by nicotine-associated cues and nicotine priming but does not affect nicotine- and food-taking
    Islam Gamaleddin
    Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health, Toronto, Canada
    J Psychopharmacol 27:564-71. 2013
    ..Our results indicate that AM404 could be a potential promising therapeutic option for the prevention of relapse to nicotine-seeking in abstinent smokers...
  14. pmc Extinction bursts in rats trained to self-administer nicotine or food in 1-h daily sessions
    Abhiram Pushparaj
    Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health Toronto, Canada
    Am J Transl Res 4:422-31. 2012
    ..This study supports the presence of a loading phase in rats trained to self-administer nicotine in 1-r daily sessions and the presence of a transient extinction burst...
  15. pmc Blockade of dopamine d4 receptors attenuates reinstatement of extinguished nicotine-seeking behavior in rats
    Yijin Yan
    Translational Addiction Research Laboratory, Centre for Addiction and Mental Health Addiction CAMH, University of Toronto, Toronto, ON, Canada
    Neuropsychopharmacology 37:685-96. 2012
    ....
  16. pmc Electrical stimulation of the insular region attenuates nicotine-taking and nicotine-seeking behaviors
    Abhiram Pushparaj
    Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health CAMH, Toronto, ON, Canada
    Neuropsychopharmacology 38:690-8. 2013
    ..Stimulation of brain slices containing the insular region was found to inactivate insular neurons. Our results suggest that deep brain stimulation to modulate insular activity should be further explored...
  17. doi request reprint Gender differences in health-related quality of life among cannabis users: results from the National Epidemiologic Survey on Alcohol and Related Conditions
    Shaul Lev-Ran
    Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, ON, Canada
    Drug Alcohol Depend 123:190-200. 2012
    ..Cannabis is the most widely used illicit substance worldwide. The aim of the present study was to assess self-reported Quality of Life (QoL) among cannabis users in a large representative sample...
  18. doi request reprint Child marriage in the United States and its association with mental health in women
    Yann Le Strat
    Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Pediatrics 128:524-30. 2011
    ..This article presents nationally representative data on the prevalence, sociodemographic correlates, and psychiatric comorbidity of child marriage among women in the United States...