Jean Pierre Lavoie

Summary

Country: Canada

Publications

  1. pmc Neutrophils are not less sensitive than other blood leukocytes to the genomic effects of glucocorticoids
    Gaelle Hirsch
    Department of Clinical Sciences, Faculty of Veterinary Medicine, Universite de Montreal, Saint Hyacinthe, Quebec, Canada
    PLoS ONE 7:e44606. 2012
  2. pmc Profiling of differentially expressed genes using suppression subtractive hybridization in an equine model of chronic asthma
    Jean Pierre Lavoie
    Department of Clinical Sciences, Faculty of Veterinary Medicine, Universite de Montreal, Saint Hyacinthe, Quebec, Canada
    PLoS ONE 7:e29440. 2012
  3. ncbi Neutrophilic airway inflammation in horses with heaves is characterized by a Th2-type cytokine profile
    J P Lavoie
    Faculte de Medecine Veterinaire, Universite de Montreal, St Hyacinthe, Quebec, Canada
    Am J Respir Crit Care Med 164:1410-3. 2001
  4. ncbi Bronchiectasis in three adult horses with heaves
    Jean Pierre Lavoie
    Department of Clinical Sciences, Faculte de Medecine Veterinaire, Universite de Montreal, St Hyacinthe, QC, Canada J2S 7C6
    J Vet Intern Med 18:757-60. 2004
  5. ncbi Lack of clinical efficacy of a phosphodiesterase-4 inhibitor for treatment of heaves in horses
    Jean Pierre Lavoie
    Faculte de Medecine Veterinaire, Universite de Montreal, QC, Canada
    J Vet Intern Med 20:175-81. 2006
  6. ncbi Conjugates of ovalbumin and monomethoxypolyethylene glycol abolish late allergic responses and decrease IL-4 and IL-5 mRNA expression in the rat
    J P Lavoie
    Department de Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, 3200 Sicotte CP5000, St Hyacinthe, Que, Canada J2S 7C6
    Pulm Pharmacol Ther 16:361-9. 2003
  7. doi Bronchoalveolar lavage fluid cytology and cytokine messenger ribonucleic Acid expression of racehorses with exercise intolerance and lower airway inflammation
    J P Lavoie
    Departement de Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, Saint Hyacinthe, QC, Canada
    J Vet Intern Med 25:322-9. 2011
  8. doi Corticosteroids and antigen avoidance decrease airway smooth muscle mass in an equine asthma model
    Mathilde Leclere
    Department of Veterinary Clinical Sciences, Universite de Montreal, Saint Hyacinthe, Quebec, Canada
    Am J Respir Cell Mol Biol 47:589-96. 2012
  9. ncbi IL-4, IL-5 and IFN-gamma mRNA expression in pulmonary lymphocytes in equine heaves
    Marie Eve Cordeau
    Faculte de Medecine Veterinaire, Universite de Montreal, 3200 Sicotte, St Hyacinthe, Que, Canada J2S 7C6
    Vet Immunol Immunopathol 97:87-96. 2004
  10. doi IL-4 activates equine neutrophils and induces a mixed inflammatory cytokine expression profile with enhanced neutrophil chemotactic mediator release ex vivo
    Anouk Lavoie-Lamoureux
    Departement de Sciences Cliniques, Universite de Montreal, Saint Hyacinthe, Quebec, Canada
    Am J Physiol Lung Cell Mol Physiol 299:L472-82. 2010

Collaborators

Detail Information

Publications47

  1. pmc Neutrophils are not less sensitive than other blood leukocytes to the genomic effects of glucocorticoids
    Gaelle Hirsch
    Department of Clinical Sciences, Faculty of Veterinary Medicine, Universite de Montreal, Saint Hyacinthe, Quebec, Canada
    PLoS ONE 7:e44606. 2012
    ..Few comparative studies of glucocorticoid effects in neutrophils and other leukocytes have been reported and a relative insensitivity of neutrophils to these drugs could not be ruled out...
  2. pmc Profiling of differentially expressed genes using suppression subtractive hybridization in an equine model of chronic asthma
    Jean Pierre Lavoie
    Department of Clinical Sciences, Faculty of Veterinary Medicine, Universite de Montreal, Saint Hyacinthe, Quebec, Canada
    PLoS ONE 7:e29440. 2012
    ..Due to ethical considerations, there is currently limited information on the transcriptome profile of the peripheral lung tissues in asthma...
  3. ncbi Neutrophilic airway inflammation in horses with heaves is characterized by a Th2-type cytokine profile
    J P Lavoie
    Faculte de Medecine Veterinaire, Universite de Montreal, St Hyacinthe, Quebec, Canada
    Am J Respir Crit Care Med 164:1410-3. 2001
    ..Here we show that inflammatory cells in lungs from horses with heaves display a Th2-type cytokine profile that is consistent with the hypothesis that heaves is an allergic condition with similarity to human asthma...
  4. ncbi Bronchiectasis in three adult horses with heaves
    Jean Pierre Lavoie
    Department of Clinical Sciences, Faculte de Medecine Veterinaire, Universite de Montreal, St Hyacinthe, QC, Canada J2S 7C6
    J Vet Intern Med 18:757-60. 2004
  5. ncbi Lack of clinical efficacy of a phosphodiesterase-4 inhibitor for treatment of heaves in horses
    Jean Pierre Lavoie
    Faculte de Medecine Veterinaire, Universite de Montreal, QC, Canada
    J Vet Intern Med 20:175-81. 2006
    ..These findings suggest that the PDE 4 enzyme is not a key mediator of lung inflammation in heaves...
  6. ncbi Conjugates of ovalbumin and monomethoxypolyethylene glycol abolish late allergic responses and decrease IL-4 and IL-5 mRNA expression in the rat
    J P Lavoie
    Department de Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, 3200 Sicotte CP5000, St Hyacinthe, Que, Canada J2S 7C6
    Pulm Pharmacol Ther 16:361-9. 2003
    ....
  7. doi Bronchoalveolar lavage fluid cytology and cytokine messenger ribonucleic Acid expression of racehorses with exercise intolerance and lower airway inflammation
    J P Lavoie
    Departement de Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, Saint Hyacinthe, QC, Canada
    J Vet Intern Med 25:322-9. 2011
    ..Thus, we evaluated the mRNA expression of selected cytokines in BAL cells in racehorses with exercise intolerance and lower airway inflammation...
  8. doi Corticosteroids and antigen avoidance decrease airway smooth muscle mass in an equine asthma model
    Mathilde Leclere
    Department of Veterinary Clinical Sciences, Universite de Montreal, Saint Hyacinthe, Quebec, Canada
    Am J Respir Cell Mol Biol 47:589-96. 2012
    ..Inhaled corticosteroids may accelerate the reversal of smooth muscle remodeling, even if airway inflammation is better controlled with antigen avoidance...
  9. ncbi IL-4, IL-5 and IFN-gamma mRNA expression in pulmonary lymphocytes in equine heaves
    Marie Eve Cordeau
    Faculte de Medecine Veterinaire, Universite de Montreal, 3200 Sicotte, St Hyacinthe, Que, Canada J2S 7C6
    Vet Immunol Immunopathol 97:87-96. 2004
    ..In this study we have shown that BAL lymphocytes of horses with heaves during clinical exacerbation have a predominant Th2-type cytokine response and that this response coincides in time with the presence of airway obstruction...
  10. doi IL-4 activates equine neutrophils and induces a mixed inflammatory cytokine expression profile with enhanced neutrophil chemotactic mediator release ex vivo
    Anouk Lavoie-Lamoureux
    Departement de Sciences Cliniques, Universite de Montreal, Saint Hyacinthe, Quebec, Canada
    Am J Physiol Lung Cell Mol Physiol 299:L472-82. 2010
    ..Overall, results from this study add to the link between Th2-driven inflammation and neutrophilia in the equine model and further extend the characterization of IL-4 effects on neutrophils...
  11. doi Thoracoscopic lung biopsies in heaves-affected horses using a bipolar tissue sealing system
    Fabien Relave
    Departement de Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, Saint Hyacinthe, QC, Canada
    Vet Surg 39:839-46. 2010
    ..To validate the use of the LigaSure™ Vessel Sealing System (LVSS) to perform thoracoscopic lung tissue biopsies in heaves-affected horses...
  12. ncbi Chronic exacerbation of equine heaves is associated with an increased expression of interleukin-17 mRNA in bronchoalveolar lavage cells
    Marie Debrue
    Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Montreal, 3200 Sicotte, Saint Hyacinthe, Que, Canada J2S7C6
    Vet Immunol Immunopathol 105:25-31. 2005
    ..These preliminary results suggest that IL-17 may contribute in the pathogenesis of horses with heaves following chronic antigen challenge...
  13. doi Effect of antigenic exposure on airway smooth muscle remodeling in an equine model of chronic asthma
    Mathilde Leclere
    DVM, Departement de Sciences Cliniques, Faculte de Medecine Veterinaire, 3200 Sicotte, Saint Hyacinthe, Quebec J2S 7C6, Canada
    Am J Respir Cell Mol Biol 45:181-7. 2011
    ..This increased mass is maintained in a dynamic equilibrium by an elevated cellular turnover, suggesting that targeting smooth muscle proliferation could be effective at decreasing chronic remodeling...
  14. doi Systemic inflammation and priming of peripheral blood leukocytes persist during clinical remission in horses with heaves
    Anouk Lavoie-Lamoureux
    Faculte de Medecine Veterinaire, Departement de Sciences Cliniques, U of Montreal, 3200 rue Sicotte St Hyacinthe, Quebec, Canada
    Vet Immunol Immunopathol 146:35-45. 2012
    ..To compare innate immune responses of peripheral blood leukocytes from healthy and asymptomatic heaves-affected horses...
  15. ncbi Comparison of TGF-beta 1 concentrations in bronchoalveolar fluid of horses affected with heaves and of normal controls
    Isabelle Desjardins
    Departement de Sciences Cliniques, Faculte de Medecine Veterinaire, University de Montreal, St Hyacinthe, Canada J2S 7C6
    Vet Immunol Immunopathol 101:133-41. 2004
    ..Other studies are necessary for a better definition of the role of this cytokine within the lung, as our study does not establish a causal relationship between TGF-beta1 and the pathophysiology of heaves in the horse...
  16. ncbi Expression of interleukin (IL)-5 and IL-9 receptors on neutrophils of horses with heaves
    Oday Dewachi
    Meakins Christie Laboratories, McGill University, 3650 St Urbain, Montreal, Que, Canada
    Vet Immunol Immunopathol 109:31-6. 2006
    ..These results provide a possible mechanism by which Th2-type cytokines may activate neutrophils in equine heaves...
  17. ncbi Effects of pentoxifylline on pulmonary function and results of cytologic examination of bronchoalveolar lavage fluid in horses with recurrent airway obstruction
    Renaud Leguillette
    Departement des Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, QC, Canada
    Am J Vet Res 63:459-63. 2002
    ..To determine the effects of pentoxifylline (PTX) administration on lung function and results of cytologic examination of bronchoalveolar lavage fluid in horses affected by recurrent airway obstruction (RAO)...
  18. ncbi Comparison of effects of dexamethasone and the leukotriene D4 receptor antagonist L-708,738 on lung function and airway cytologic findings in horses with recurrent airway obstruction
    Jean Pierre Lavoie
    Department of Clinical Sciences, Faculte de Medecine Veterinaire, Universite de Montreal, St Hyacinthe, QC, Canada
    Am J Vet Res 63:579-85. 2002
    ..To evaluate whether the leukotriene (LT) D4 receptor antagonist L-708,738 is therapeutically beneficial in treating horses with recurrent airway obstruction (heaves)...
  19. ncbi Cytokine expression by peripheral blood neutrophils from heaves-affected horses before and after allergen challenge
    Philippe Joubert
    Universite de Montreal, Faculte de Medecine Veterinaire, Departement de Sciences Cliniques, C P 5000, St Hyacinthe, Quebec, Canada J2S 7C6
    Vet J 178:227-32. 2008
    ....
  20. doi Evaluation of variations in bronchoalveolar lavage fluid in horses with recurrent airway obstruction
    Daniel Jean
    Departement de Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, Saint Hyacinthe, QC J2S 7C6, Canada
    Am J Vet Res 72:838-42. 2011
    ..To determine variations in cytologic counts of bronchoalveolar lavage (BAL) fluid attributable to month of collection, first and second aliquots, and left and right lung sites in horses with recurrent airway obstruction (RAO)...
  21. doi Cytokine mRNA expression of pulmonary macrophages varies with challenge but not with disease state in horses with heaves or in controls
    Philippe Joubert
    Departement de Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, St Hyacinthe, QC, Canada
    Vet Immunol Immunopathol 142:236-42. 2011
    ....
  22. doi Heaves, an asthma-like disease of horses
    Mathilde Leclere
    Department of Clinical Sciences, Faculty of Veterinary Medicine, Universite de Montreal, St Hyacinthe, Canada
    Respirology 16:1027-46. 2011
    ....
  23. ncbi Cytokine and chemokine gene expression of IL-1beta stimulated equine articular chondrocytes
    Florent David
    Departement de Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, Saint Hyacinthe, Quebec, Canada J2S 7C6
    Vet Surg 36:221-7. 2007
    ..To evaluate mRNA expression of several proinflammatory and anti-inflammatory cytokines and chemokines in equine unstimulated and interleukin-1beta (IL-1beta)-stimulated chondrocytes...
  24. ncbi IL-4 stimulates the expression of CXCL-8, E-selectin, VEGF, and inducible nitric oxide synthase mRNA by equine pulmonary artery endothelial cells
    Hong Huang
    Department of Clinical Sciences, Faculty of Veterinary Medicine, Universite de Montreal, Saint Hyacinthe, Quebec, Canada
    Am J Physiol Lung Cell Mol Physiol 292:L1147-54. 2007
    ..DXM and the iNOS inhibitors may decrease pulmonary neutrophilia due, in part, to a direct inhibition of some of these factors...
  25. pmc Diagnostic and epidemiological features of Lawsonia intracellularis enteropathy in 2 foals
    Julie Dauvillier
    Departement de Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, 3200 Sicotte, Saint Hyacinthe, Quebec
    Can Vet J 47:689-91. 2006
    ..One foal was serologically positive 3 days after onset of clinical signs and remained positive for more than 6 months...
  26. ncbi Comparison of four staining methods for detection of mast cells in equine bronchoalveolar lavage fluid
    Mathilde Leclere
    Department of Clinical Sciences, Faculty of Veterinary Medicine, Universite de Montreal, Saint Hyacinthe, Quebec, Canada
    J Vet Intern Med 20:377-81. 2006
    ..In conclusion, fast Romanosky stain may be inadequate for detection of mast cells in equine BALF, whereas automated Romanowsky, May-Grünwald Giemsa, and toluidine blue stains provide metachromatic staining of mast cell granules...
  27. ncbi Clinical application of Patlak plot CT-GFR in animals with upper urinary tract disease
    Kate Alexander
    Departement de Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, PO Box 5000, St Hyacinthe, QC, Canada J2S 7C6
    Vet Radiol Ultrasound 51:421-7. 2010
    ..There was a significant relationship between CT-GFR and serum creatinine values, which supports the clinical potential of CT-GFR and justifies further investigation of this technique...
  28. doi Optimization of a procedure to accurately detect equine TNFα in serum samples
    Anouk Lavoie-Lamoureux
    Faculte de Medecine Veterinaire, Universite de Montreal, 3200 rue Sicotte, St Hyacinthe, J2S2M2 Québec, Canada
    Vet Immunol Immunopathol 138:118-23. 2010
    ..The specificity of TNFα detection was also assessed. Our optimized assay conditions were validated by quantifying levels of TNFα in serum samples from normal horses and horses affected with chronic pulmonary disease (heaves)...
  29. doi Evaluation of a modified thrombelastography assay initiated with recombinant human tissue factor in clinically healthy horses
    Mathilde Leclere
    Department of Clinical Sciences, Faculty of Veterinary Medicine, Universite de Montreal, Saint Hyacinthe, QC, Canada
    Vet Clin Pathol 38:462-6. 2009
    ..TEG analysis initiated with recombinant human tissue factor (TF) has not been evaluated in clinically healthy horses...
  30. doi [Responsibilities of elderly support: normative expectations with regard of ex-spouses and step-children]
    Nicolas Rousseau
    Centre de recherche et d expertise de gérontologie sociale, CSSS Cavendish CAU, 5800 Boul Cavendish, Suite 600, Côte St Luc, Quebec H4W 2T5, Canada
    Can J Aging 27:371-83. 2008
    ..Where offspring are specifically concerned, expectations are strongly influenced by the given context; for this category of survey-taker, the demands of support should not interfere with their family life and career...
  31. ncbi Transvenous pacing leads and systemic thromboemboli in patients with intracardiac shunts: a multicenter study
    Paul Khairy
    Adult Congenital Heart and Electrophysiology Services, Montreal Heart Institute, Montreal, Canada
    Circulation 113:2391-7. 2006
    ..The risk of systemic thromboemboli associated with transvenous leads in the presence of an intracardiac shunt is currently unknown...
  32. pmc Genetic relatedness of recent Canadian equine influenza virus isolates with vaccine strains used in the field
    Carl A Gagnon
    Groupe de Recherche sur les Maladies Infectieuses du Porc
    Can Vet J 48:1028-30. 2007
  33. ncbi Effects of syringe type and storage temperature on results of blood gas analysis in arterial blood of horses
    Valerie Picandet
    Department of Clinical Sciences, Faculty of Veterinary Medicine, Universite de Montreal, Saint Hyacinthe, QC, Canada
    J Vet Intern Med 21:476-81. 2007
    ..However, the acceptable delay between time of collection and analysis for equine arterial blood gas remains unknown...
  34. pmc [Evolution of bacterial resistance to certain antibacterial agents in horses in a veterinary hospital]
    Mathieu Peyrou
    Departement de Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, Saint Hyacinthe Québec J2S 7C6
    Can Vet J 44:978-81. 2003
    ..The adoption of "good antibiotherapy practices" is essential to guarantee a decrease in the risks of selection and dissemination of a resistant bacterial strain...
  35. ncbi Effects of the bronchoalveolar lavage procedure on lung function in horses with clinical exacerbation of recurrent airway obstruction
    Renaud Leguillette
    Department de Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, St Hyacinthe, QC J2S 7C6, Canada
    Am J Vet Res 67:1929-33. 2006
    ..To evaluate whether bronchoalveolar lavage (BAL) alters respiratory mechanics of horses with recurrent airway obstruction (ie, heaves) over a 48-hour period...
  36. doi Evaluation of a thoracoscopic technique using ligating loops to obtain large lung biopsies in standing healthy and heaves-affected horses
    Fabien Relave
    Departement des Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, 3200 Sicotte, Saint Hyacinthe, Quebec, J2S 7C6, Canada
    Vet Surg 37:232-40. 2008
    ..To evaluate use of pre-tied ligating loop to perform thoracoscopic, large lung biopsy in normal and heaves-affected horses...
  37. doi Baby Boom caregivers: care in the age of individualization
    Nancy Guberman
    School of Social Work, University of Quebec in Montreal, Montreal, Quebec, Canada
    Gerontologist 52:210-8. 2012
    ..This study examines how Baby Boomers in Quebec, Canada, perceive and play their role as caregivers and how this might differ from their parents' generation...
  38. ncbi Formal service practitioners' views of family caregivers' responsibilities and difficulties
    Nancy Guberman
    Ecole de Travail social, Universite du Quebec a Montreal, QC, H3C 3P8, Canada
    Can J Aging 25:43-53. 2006
    ..Our analysis offers an explanation for this apparent contradiction by examining practitioners' values with regard to family responsibility for care...
  39. ncbi Efficacy of a psychoeducative group program for caregivers of demented persons living at home: a randomized controlled trial
    Réjean Hébert
    Research Centre on Aging, Sherbrooke Geriatric University Institute, Quebec, Canada
    J Gerontol B Psychol Sci Soc Sci 58:S58-67. 2003
    ..To test the efficacy of a psychoeducative group program for informal caregivers of persons with dementia...
  40. doi Characterization of arginase expression by equine neutrophils
    Anouk Lavoie-Lamoureux
    Faculté de Médicine Vétérinaire, Dép de sciences cliniques, Universite de Montreal, St Hyacinthe, Canada
    Vet Immunol Immunopathol 157:206-13. 2014
    ..Ex vivo inhibition of arginase activity by nor-NOHA had no effect on neutrophils inflammatory gene expression induced by LPS/fMLP (5h) but significantly reversed the cell loss observed after this stimulation...
  41. ncbi Glanzmann thrombasthenia in an Oldenbourg filly
    Susana Macieira
    Department of Clinical Sciences, Faculty of Veterinary Medicine, Universite de Montreal, Saint Hyacinthe, Quebec, Canada
    Vet Clin Pathol 36:204-8. 2007
    ..The laboratory findings supported a diagnosis of Glanzmann thrombasthenia, likely caused by a mutation in the gene encoding the GPIIb subunit...
  42. doi Evaluation of athletic performance in horses with jugular vein thrombophlebitis: 91 cases (1988-2005)
    Peggy Moreau
    Departement de Sciences Cliniques, Faculte de Medecine Veterinaire, Universite de Montreal, Saint Hyacinthe, QC, Canada
    J Am Vet Med Assoc 235:1073-8. 2009
    ..To evaluate effects of thrombophlebitis of 1 or both jugular veins on athletic performance of horses...
  43. ncbi Development of an electrospray ionization mass spectrometric method for the quantification of theophylline in horse serum
    Francis Beaudry
    Department of Veterinary Biomedicine, Faculty of Veterinary Medicine, University of Montreal, St Hyacinthe, QC, Canada
    Biomed Chromatogr 19:643-8. 2005
    ..9%, respectively. This LC-ESI/MS/MS method for the determination of theophylline in horse serum has been proved to within generally accepted criteria used for bioanalytical assay and was used successfully during clinical investigation...
  44. ncbi Families' values and attitudes regarding responsibility for the frail elderly: implications for aging policy
    Nancy Guberman
    School of Social Work, University of Quebec, Montreal, Quebec, H3C 3P8, Canada
    J Aging Soc Policy 18:59-78. 2006
    ..This article discusses these seemingly paradoxical results and their implications for aging policy...
  45. ncbi Heaves, an asthma-like equine disease, involves airway smooth muscle remodeling
    Berenice Herszberg
    Meakins Christie Laboratories, McGill University, 3626 Saint Urbain, Montreal, Quebec H2X 2P2, Canada
    J Allergy Clin Immunol 118:382-8. 2006
    ..Airway smooth muscle hyperplasia occurs in rodent models of experimental asthma, but the relevance of such finding to spontaneously occurring disease in large mammals is unknown...
  46. ncbi Inflammatory airway disease of horses
    Laurent L Couetil
    Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Purdue University, West Lafayette, IN, USA
    J Vet Intern Med 21:356-61. 2007
    ....
  47. ncbi Tools for the diagnosis of equine respiratory disorders
    Marie France Roy
    Center for the Study of Host Resistance, Montreal General Hospital Research Institute, McGill University, 1650 Cedar Avenue, Room Lll 513, Montreal, Quebec H3G 1A4, Canada
    Vet Clin North Am Equine Pract 19:1-17, v. 2003
    ..Physical and endoscopic examination, radiology, diagnostic ultrasound, techniques for sampling the respiratory tract, hematology, blood gas analysis, respiratory mechanics, and some modern diagnostic tools are briefly covered...