Yves Lacourciere

Summary

Country: Canada

Publications

  1. ncbi Comparison of fixed-dose combinations of telmisartan/hydrochlorothiazide 40/12.5 mg and 80/12.5 mg and a fixed-dose combination of losartan/hydrochlorothiazide 50/12.5 mg in mild to moderate essential hypertension: pooled analysis of two multicenter, pros
    Yves Lacourciere
    Unité d hypertension, Centre hospitalier de l Universite Laval, Universite Laval, 2705 Boulevard Laurier S 120, Sainte Foy, Quebec G1V 4G2, Quebec, Canada
    Clin Ther 27:1795-805. 2005
  2. doi Valsartan plus hydrochlorothiazide for first-line therapy in hypertension
    Yves Lacourciere
    Hypertension Research Unit, Centre hospitalier de l Universite Laval, Quebec, QC, G1V 4G2, Canada
    Expert Rev Cardiovasc Ther 7:1491-501. 2009
  3. doi Telmisartan or valsartan alone or in combination with hydrochlorothiazide: a review
    Yves Lacourciere
    Hypertension Unit, Centre Hospitalier Universitaire de Quebec, Quebec, Canada
    Clin Exp Hypertens 35:50-60. 2013
  4. ncbi A multicenter, 14-week study of telmisartan and ramipril in patients with mild-to-moderate hypertension using ambulatory blood pressure monitoring
    Yves Lacourciere
    Hypertension Research Unit, CHUL, Centre Hospitalier Universitaire de Quebec, 2705 boulevard Laurier S 135, Sainte Foy, Quebec, QC G1V 4G2, Canada
    Am J Hypertens 19:104-12. 2006
  5. doi Effects of force-titrated valsartan/hydrochlorothiazide versus amlodipine/hydrochlorothiazide on ambulatory blood pressure in patients with stage 2 hypertension: the EVALUATE study
    Yves Lacourciere
    Centre hospitalier de l Universite Laval, Sainte Foy, Quebec, Canada
    Blood Press Monit 14:112-20. 2009
  6. pmc Expedited blood pressure control with initial angiotensin II antagonist/diuretic therapy compared with stepped-care therapy in patients with ambulatory systolic hypertension
    Yves Lacourciere
    Hypertension Research Unit, Centre hospitalier de l Universite Laval, Sainte Foy, Quebec, Canada
    Can J Cardiol 23:377-82. 2007
  7. pmc Increasing the doses of both diuretics and angiotensin receptor blockers is beneficial in subjects with uncontrolled systolic hypertension
    Yves Lacourciere
    Centre hospitalier de l Universite Laval, Quebec, Canada
    Can J Cardiol 26:313-9. 2010
  8. ncbi Sustained antihypertensive activity of telmisartan compared with valsartan
    Yves Lacourciere
    Hypertension Research Unit, Centre Hospitalier l Université de Quebec, Ste Foy, Quebec, Canada
    Blood Press Monit 9:203-10. 2004
  9. ncbi A comparison of the efficacy and duration of action of telmisartan, amlodipine and ramipril in patients with confirmed ambulatory hypertension
    Luc Poirier
    Unité d hypertension, Centre hospitalier de l Universite Laval, Universite Laval, 2705 Boulevard Laurier S 120 A, Sainte Foy, Quebec, Canada G1V 4G2
    Blood Press Monit 9:231-6. 2004
  10. pmc Effects of aerobic exercise training and irbesartan on blood pressure and heart rate variability in patients with chronic obstructive pulmonary disease
    Karine Marquis
    Centre de Recherche de l Hopital Laval, Institut universitaire de cardiologie et de pneumoloigie de L Université Laval, Quebec, Canada
    Can Respir J 15:355-60. 2008

Detail Information

Publications22

  1. ncbi Comparison of fixed-dose combinations of telmisartan/hydrochlorothiazide 40/12.5 mg and 80/12.5 mg and a fixed-dose combination of losartan/hydrochlorothiazide 50/12.5 mg in mild to moderate essential hypertension: pooled analysis of two multicenter, pros
    Yves Lacourciere
    Unité d hypertension, Centre hospitalier de l Universite Laval, Universite Laval, 2705 Boulevard Laurier S 120, Sainte Foy, Quebec G1V 4G2, Quebec, Canada
    Clin Ther 27:1795-805. 2005
    ..Thus, control of BP at this time of day, using oral fixed-dose combinations (FDCs) as required, is important in reducing cardiovascular risk in hypertensive patients...
  2. doi Valsartan plus hydrochlorothiazide for first-line therapy in hypertension
    Yves Lacourciere
    Hypertension Research Unit, Centre hospitalier de l Universite Laval, Quebec, QC, G1V 4G2, Canada
    Expert Rev Cardiovasc Ther 7:1491-501. 2009
    ..The focus of this article is on those randomized, double-blind trials in which this combination was administered as first-line therapy in patients with essential hypertension...
  3. doi Telmisartan or valsartan alone or in combination with hydrochlorothiazide: a review
    Yves Lacourciere
    Hypertension Unit, Centre Hospitalier Universitaire de Quebec, Quebec, Canada
    Clin Exp Hypertens 35:50-60. 2013
    ..These findings suggest that pharmacologic differences between telmisartan and valsartan may translate into clinically relevant differences between the two drugs in the management of hypertension...
  4. ncbi A multicenter, 14-week study of telmisartan and ramipril in patients with mild-to-moderate hypertension using ambulatory blood pressure monitoring
    Yves Lacourciere
    Hypertension Research Unit, CHUL, Centre Hospitalier Universitaire de Quebec, 2705 boulevard Laurier S 135, Sainte Foy, Quebec, QC G1V 4G2, Canada
    Am J Hypertens 19:104-12. 2006
    ....
  5. doi Effects of force-titrated valsartan/hydrochlorothiazide versus amlodipine/hydrochlorothiazide on ambulatory blood pressure in patients with stage 2 hypertension: the EVALUATE study
    Yves Lacourciere
    Centre hospitalier de l Universite Laval, Sainte Foy, Quebec, Canada
    Blood Press Monit 14:112-20. 2009
    ..Previous studies using the combination of angiotensin-receptor blockers and hydrochlorothiazide (HCTZ) have shown superior ambulatory blood pressure (ABP) reduction in study participants with stage 2 hypertension compared with monotherapy...
  6. pmc Expedited blood pressure control with initial angiotensin II antagonist/diuretic therapy compared with stepped-care therapy in patients with ambulatory systolic hypertension
    Yves Lacourciere
    Hypertension Research Unit, Centre hospitalier de l Universite Laval, Sainte Foy, Quebec, Canada
    Can J Cardiol 23:377-82. 2007
    ....
  7. pmc Increasing the doses of both diuretics and angiotensin receptor blockers is beneficial in subjects with uncontrolled systolic hypertension
    Yves Lacourciere
    Centre hospitalier de l Universite Laval, Quebec, Canada
    Can J Cardiol 26:313-9. 2010
    ..Current clinical practice usually limits the daily dose of HCTZ to 25 mg. This often leads to the necessity of using additional antihypertensive agents to control BP in a high proportion of patients...
  8. ncbi Sustained antihypertensive activity of telmisartan compared with valsartan
    Yves Lacourciere
    Hypertension Research Unit, Centre Hospitalier l Université de Quebec, Ste Foy, Quebec, Canada
    Blood Press Monit 9:203-10. 2004
    ..The efficacies of the long half-life telmisartan compared with shorter half-life valsartan in the last 6 h of the dosing interval following active treatment and during 24 h after a missed dose were compared...
  9. ncbi A comparison of the efficacy and duration of action of telmisartan, amlodipine and ramipril in patients with confirmed ambulatory hypertension
    Luc Poirier
    Unité d hypertension, Centre hospitalier de l Universite Laval, Universite Laval, 2705 Boulevard Laurier S 120 A, Sainte Foy, Quebec, Canada G1V 4G2
    Blood Press Monit 9:231-6. 2004
    ..The aim of the study was to compare the antihypertensive effects and the duration of action of telmisartan, amlodipine and ramipril in patients with mild-to-moderate hypertension using ambulatory blood pressure (ABP) monitoring...
  10. pmc Effects of aerobic exercise training and irbesartan on blood pressure and heart rate variability in patients with chronic obstructive pulmonary disease
    Karine Marquis
    Centre de Recherche de l Hopital Laval, Institut universitaire de cardiologie et de pneumoloigie de L Université Laval, Quebec, Canada
    Can Respir J 15:355-60. 2008
    ....
  11. ncbi Methodology to determine duration of action for antihypertensive drugs
    Jean Lefebvre
    Hypertension Research Unit, Le Centre Hospitalier Universitaire de Quebec, Pavillon CHUL, 2705 Blvd Laurier, Sainte Foy, Quebec G1V 4G2, Canada
    Ann Pharmacother 36:874-81. 2002
    ..To review and comment on methods used to assess the duration of action of antihypertensive drugs...
  12. ncbi Antihypertensive efficacy and tolerability of two fixed-dose combinations of valsartan and hydrochlorothiazide compared with valsartan monotherapy in patients with stage 2 or 3 systolic hypertension: an 8-week, randomized, double-blind, parallel-group tri
    Yves Lacourciere
    Hypertension Research Unit, Centre Hospitalier de l Université Laval CHUQ, Sainte Foy, Quebec, Canada
    Clin Ther 27:1013-21. 2005
    ..A currently recommended combination is a diuretic added to an angiotensin-receptor blocker...
  13. pmc The influence of CYP2D6 phenotype on the clinical response of nebivolol in patients with essential hypertension
    Jean Lefebvre
    Hypertension Research Unit, CHUL Research Center, Faculty of Pharmacy, Laval University, Quebec, Canada
    Br J Clin Pharmacol 63:575-82. 2007
    ..The metabolism of the third-generation beta(1)-receptor antagonist nebivolol has been shown to be highly dependent on cytochrome P450 2D6 enzymatic activity in preclinical studies...
  14. ncbi Identifying which treated hypertensive patients without known coronary artery disease should be tested for the presence of myocardial ischemia by perfusion imaging
    Yves Lacourciere
    Hypertension Unit, Centre hospitalier de l Universite Laval, Quebec, Canada
    J Clin Hypertens (Greenwich) 9:921-8. 2007
    ..These study data should be clinically helpful in selecting hypertensive patients who are the most suitable candidates to screen for the presence of CAD...
  15. doi Clinic and ambulatory blood pressure lowering effect of aliskiren/amlodipine/hydrochlorothiazide combination in patients with moderate-to-severe hypertension: a randomized active-controlled trial
    Yves Lacourciere
    Unité de Recherche sur l Hypertension, Centre Hospitalier Universitaire de Québec CHUL, Quebec, Quebec, Canada
    J Hypertens 30:2047-55. 2012
    ....
  16. ncbi Antihypertensive effects of two fixed-dose combinations of losartan and hydrochlorothiazide versus hydrochlorothiazide monotherapy in subjects with ambulatory systolic hypertension
    Yves Lacourciere
    Hypertension Research Unit, Centre hospitalier de l Universite Laval, Ste Foy, Quebec, Canada
    Am J Hypertens 16:1036-42. 2003
    ..The aim of this study was to compare the effects of these treatment approaches in patients with ambulatory systolic hypertension...
  17. ncbi Effects of mild exercise on insulin sensitivity in hypertensive subjects
    Caroline Rheaume
    Hypertension Research Units, Laval University Hospital Research Center, Quebec, Canada
    Hypertension 39:989-95. 2002
    ..Endogenous insulin-induced vasodilatation is reduced in hypertensive subjects, and this insulin action is not affected by physical exercise...
  18. ncbi Comparison of a fixed-dose combination of 40 mg telmisartan plus 12.5 mg hydrochlorothiazide with 40 mg telmisartan in the control of mild to moderate hypertension
    Yves Lacourciere
    Hypertension Research Unit, Center Hospitalier Universitaire de Québec, Quebec
    Am J Ther 9:111-7. 2002
    ..5 mg HCTZ is clinically and statistically superior to 40 mg telmisartan in patients with mild to moderate hypertension failing to respond to 40 mg telmisartan alone...
  19. ncbi Impact of Levovist ultrasonographic contrast agent on the diagnosis and management of hypertensive patients with suspected renal artery stenosis: a Canadian multicentre pilot study
    Yves Lacourciere
    Centre hospitalier de l Université du Québec
    Can Assoc Radiol J 53:219-27. 2002
    ....
  20. doi The evolving role of β-adrenergic receptor blockers in managing hypertension
    Luc Poirier
    Unité d hypertension, Centre de Recherche, Centre Hospitalier Universitaire de Quebec, Quebec, Quebec, Canada
    Can J Cardiol 28:334-40. 2012
    ..The present report will describe the clinically relevant mechanisms of action of β-blockers, their pharmacological differences, their metabolic effects, and their usefulness in patients with hypertension...
  21. ncbi Effects of perindopril on elastic and structural properties of large arteries in essential hypertension
    Yves Lacourciere
    Centre hospitalier de l Universite Laval, Sainte Foy, Quebec
    Can J Cardiol 20:795-9. 2004
    ..It decreases the stiffness of the larger arteries; questions remain as to the mechanisms involved and whether it is blood pressure (BP) control-dependent...
  22. ncbi Noninvasive detection of silent coronary artery disease in patients with essential hypertension, alone or associated with type 2 diabetes mellitus, using dipyridamole stress 99mtechnetium-sestamibi myocardial perfusion imaging
    Yves Lacourciere
    Hypertension, Centre hospitalier de l Universite Laval, Sainte Foy, Quebec
    Can J Cardiol 22:16A-21A. 2006
    ..Early diagnosis of CAD and identification of high-risk subgroups, followed by appropriate therapy, may therefore enhance survival...