Research Topics
| David L StreinerSummaryAffiliation: Kunin-Lunenfeld Applied Research Unit Country: Canada Publications
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Detail Information
Publications
Diagnosing tests: using and misusing diagnostic and screening testsDavid L Streiner
Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, Toronto, Ontario, Canada M6A 2E1
J Pers Assess 81:209-19. 2003..2003) for reporting the results of diagnostic tests and extend them to cover the types of tests used by psychologists...
Investigator experiences with financial conflicts of interest in clinical trialsPaula A Rochon
Women s College Research Institute at Women s College Hospital, Toronto, Canada
Trials 12:9. 2011..We obtained information from investigators about adherence to practices that minimize the introduction of such bias in their clinical trials experience...
What's under the ROC? An introduction to receiver operating characteristics curvesDavid L Streiner
Kunin Lunenfeld Applied Research Unit, Baycrest Centre, Toronto, Ontario
Can J Psychiatry 52:121-8. 2007..We discuss how to calculate and compareROC curves and the factors that must be considered in choosing an optimal cut point...
Clinimetrics vs. psychometrics: an unnecessary distinctionDavid L Streiner
Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, M6A 2E1, Toronto, ON, Canada
J Clin Epidemiol 56:1142-5; discussion 1146-9. 2003....
Unicorns do exist: a tutorial on "proving" the null hypothesisDavid L Streiner
Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Toronto, Ontario
Can J Psychiatry 48:756-61. 2003..We then work through an example and show how to calculate sample sizes for noninferiority studies...
The lesser of 2 evils: the ethics of placebo-controlled trialsDavid L Streiner
Kunin-Lunenfeld Applied Research Unit, Baycrest Centre, Toronto, Ontario
Can J Psychiatry 53:430-2. 2008
Finding our way: an introduction to path analysisDavid L Streiner
Baycrest Centre for Geriatric Care, Toronto, Ontario
Can J Psychiatry 50:115-22. 2005..As with many techniques, path analysis has its own unique nomenclature, assumptions, and conventions, which are discussed in this paper...
With apologies to Albert: everything is not relativeDavid L Streiner
Department of Psychiatry, University of Toronto, Canada
Evid Based Ment Health 8:93. 2005
"Precision" and "accuracy": two terms that are neitherDavid L Streiner
Baycrest Centre for Geriatric Care, Department of Psychiatry, Kunin Lunenfeld Applied Research Unit, University of Toronto, 3560 Bathurst Street, Toronto, Ontario M6A 2E1, Canada
J Clin Epidemiol 59:327-30. 2006..In some publications, the terms "precision" and "accuracy" are used as if they were synonyms for "reliability" and "validity."..
The epidemiology of psychological problems in the elderlyDavid L Streiner
Department of Psychiatry, University of Toronto, Ontario
Can J Psychiatry 51:185-91. 2006..To determine the prevalence of mood, anxiety, and other disorders in the population of Canadians aged 55 years and over...
A shortcut to rejection: how not to write the results section of a paperDavid L Streiner
Kunin Lunenfield Applied Research Unit, Baycrest Centre, Department of Psychiatry, University of Toronto, Toronto, Ontario
Can J Psychiatry 52:385-9. 2007..Suggestions are made regarding the proper way to report findings...
Building a better model: an introduction to structural equation modellingDavid L Streiner
Baycrest Centre for Geriatric Care, Department of Psychiatry, University of Toronto, Toronto, Ontario
Can J Psychiatry 51:317-24. 2006..Each latent variable and its associated measured variables form small CFAs, with the added advantage that the correlations among the variables can be corrected for the unreliability of the measures...
Has 'lifetime prevalence' reached the end of its life? An examination of the conceptDavid L Streiner
Baycrest Centre and the University of Toronto, Toronto, Ontario, Canada
Int J Methods Psychiatr Res 18:221-8. 2009..Further, because lifetime prevalence is insensitive to changes in treatment effectiveness or demand for services, it is a parameter that should be dropped from the lexicon of psychiatric epidemiology...
Being inconsistent about consistency: when coefficient alpha does and doesn't matterDavid L Streiner
Baycrest Centre for Geriatric Care, Department of Psychiatry, University of Toronto, Ontario, Canada
J Pers Assess 80:217-22. 2003..I discuss the implications of this difference for how items are selected, the relationship among the items, and the statistics that should and should not be used in establishing the reliability of the scale or index...
Measure for measure: new developments in measurement and item response theoryDavid L Streiner
Kunin Lunenfeld Applied Research Unit, Baycrest Centre, Toronto, Ontario
Can J Psychiatry 55:180-6. 2010..This article is an introduction to IRT. It concludes by discussing why IRT hasn't been adopted more widely, and some of its limitations...
The case of the missing data: methods of dealing with dropouts and other research vagariesDavid L Streiner
Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Department of Psychiatry, University of Toronto, Toronto, Ontario
Can J Psychiatry 47:68-75. 2002..Growth curve analysis makes maximal use of the existing data and makes fewer assumptions...
Breaking up is hard to do: the heartbreak of dichotomizing continuous dataDavid L Streiner
Department of Psychiatry, University of Toronto, Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Toronto, ON
Can J Psychiatry 47:262-6. 2002..Dichotomizing a continuous variable is justified only when the distribution of that variable is highly skewed or its relation with another variable is nonlinear...
The 2 "Es" of research: efficacy and effectiveness trialsDavid L Streiner
Applied Research Unit, Baycrest Centre for Geriatric Care, Department of Psychiatry, University of Toronto, Toronto, Ontario
Can J Psychiatry 47:552-6. 2002..This paper explores these issues, shows the decisions researchers must take at each phase of a trial, and discusses how clinicians should interpret the results...
Missing data and the trouble with LOCFDavid L Streiner
Kunin-Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care and Professor, Department of Psychiatry, University of Toronto, Canada
Evid Based Ment Health 11:3-5. 2008
Starting at the beginning: an introduction to coefficient alpha and internal consistencyDavid L Streiner
Baycrest Centre for Geriatric Care, Toronto, Ontario, Canada
J Pers Assess 80:99-103. 2003..It provides some recommendations for acceptable values of a in different situations...
Impact of extreme prematurity on family functioning and maternal health 20 years laterSaroj Saigal
McMaster University, Department of Pediatrics, Hamilton, ON, Canada
Pediatrics 126:e81-8. 2010....
The effect of cholinesterase inhibitors on decline in multiple functional domains in Alzheimer's disease: a two-year observational study in the Sunnybrook dementia cohortPearl Behl
Linda C Campbell Cognitive Neurology Research Unit, University of Toronto, Canada
Int Psychogeriatr 20:1141-59. 2008..This study seeks to assess change in activities of daily living (ADLs) over two years in AD patients treated with CHEIs matched to untreated patients in the same longitudinal cohort study...
Comorbid depression and anxiety in later life: patterns of association, subjective well-being, and impairmentJohn Cairney
Health Systems Research and Consulting Unit, Centre for Addiction and Mental Health, Department of Psychiatry, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, ON
Am J Geriatr Psychiatry 16:201-8. 2008..In this study, the authors examine psychiatric comorbidity and associated impairment of four disorders (major depression, panic disorder, social phobia, and agoraphobia) in a community-based sample of adults aged 55 and older...
The inclusion of minority groups in clinical trials: problems of under representation and under reporting of dataPaula A Rochon
Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, 3560 Bathurst St, Toronto, ON M6A 2E1, Canada
Account Res 11:215-23. 2004..This suggests that mandatory reporting policies may have a positive effect on both reporting and representation...
Suicide ideation in older adults: relationship to mental health problems and service useLaurie M Corna
Dalla Lana School of Public Health, University of Toronto, 155 College St, Toronto, ON, Canada M5T 3M7
Gerontologist 50:785-97. 2010..to assess the prevalence of suicide ideation among community-dwelling older adults and the relationship between suicide ideation, major psychiatric disorder, and mental health service use...
The impact of rural residence on medically serious medicinal self-poisoningsAnne Rhodes
Suicide Studies Unit, St Michael s Hospital, Toronto, ON, Canada M5B 1W8
Gen Hosp Psychiatry 30:552-60. 2008....
Does psychological well-being influence oral-health-related quality of life reports in children receiving orthodontic treatment?Shoroog Agou
Faculty of Dentistry, King Abdulaziz University, University of Toronto, Toronto, Ontario, Canada
Am J Orthod Dentofacial Orthop 139:369-77. 2011..We postulated that children with better psychological well-being (PWB) would experience fewer negative OHRQOL impacts, regardless of their orthodontic treatment status...
Dialectical behavior therapy compared with general psychiatric management for borderline personality disorder: clinical outcomes and functioning over a 2-year follow-upShelley F McMain
Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Am J Psychiatry 169:650-61. 2012....
Transitions in hearing impairment and psychological distress in older adultsLaurie M Corna
Department of Public Health Sciences, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario
Can J Psychiatry 54:518-25. 2009....
Stroke survivor depressive symptoms are associated with family caregiver depression during the first 2 years poststrokeJill I Cameron
University of Toronto, Department of Occupational Science and Occupational Therapy, Toronto, Ontario, Canada M5G 1V7
Stroke 42:302-6. 2011..A subsample completed additional assessments 18 and 24 months poststroke. These longitudinal data were analyzed using mixed effects modeling...
Age-sex differences in medicinal self-poisonings: a population-based study of deliberate intent and medical severityAnne E Rhodes
Suicide Studies Unit, St Michael s Hospital, 2 Shuter Wing 2010f, 30 Bond Street, Toronto, ON, M5B 1W8, Canada
Soc Psychiatry Psychiatr Epidemiol 43:642-52. 2008..Such knowledge can guide prevention strategies emphasizing detecting and treating mental illness and controlling access to means...
Evaluation of an assessment battery for estimating dementia caregiver needs for health and social care servicesElsa Marziali
Kunin Lunenfeld Applied Research Unit, Baycrest, Toronto, Ontario, Canada
Am J Alzheimers Dis Other Demen 25:446-54. 2010..The aim of this study was to examine a battery of questionnaires for assessing the personal resources and vulnerabilities of family caregivers of persons with dementia (Alzheimer or other)...
Factor structure and reliability of the brain impairment behavior scaleJill I Cameron
Department of Occupational Science and Occupational Therapy, University of Toronto, Toronto, Ontario, Canada
J Neurosci Nurs 40:40-7. 2008..75 to .88. Future research and clinical use of this measure will increase our understanding of how specific domains of stroke survivors' behavioral and psychological symptoms affect the well-being of family caregivers...
Smell test predicts performance on delayed recall memory test in elderly with depressionMonica Z Scalco
Department of Psychiatry, Baycrest, Toronto, Ontario, Canada
Int J Geriatr Psychiatry 24:376-81. 2009..Smell tests are correlated with performance on cognitive tests in the elderly and therefore might serve as a screening test for cognitive impairment in depressed elderly...
Disease characteristics and psychosocial factors: explaining the expression of quality of life in childhood epilepsyGabriel M Ronen
Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
Epilepsy Behav 18:88-93. 2010..To explore, identify and understand the contribution that biomedical and psychosocial factors make to the assessment of health-related quality of life (HRQL) of children and youth with epilepsy using the CHEQOL-25...
Does systems integration affect continuity of mental health care?Janet Durbin
Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
Adm Policy Ment Health 33:705-17. 2006..Future research should evaluate a wider range of systems integrating mechanisms, using client-based measures that more directly represent continuity of care experiences...
Corrected and uncorrected hearing impairment in older CanadiansLaurie M Corna
Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
Gerontology 55:468-76. 2009..Hearing impairment (HI) is a common chronic condition in later life, but one that can often be improved with the use of a hearing aid. However, a distinction is not often made between corrected and uncorrected HI in the literature...
Health-related quality of life in childhood epilepsy: moving beyond 'seizure control with minimal adverse effects'Gabriel M Ronen
Department of Pediatrics, McMaster University, 1200 Main Street West, Hamilton, Ontario, Canada
Health Qual Life Outcomes 1:36. 2003..Finally, clinicians need to familiarize themselves with outcome measures, be able to evaluate them, and use them routinely in their day-to-day practice...
Does greater frequency of contact with general physicians reduce feelings of mastery in older adults?John Cairney
Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto, Ontario, Canada
J Gerontol B Psychol Sci Soc Sci 62:P226-9. 2007....
The sensitivity of the K6 as a screen for any disorder in community mental health surveys: a cautionary noteScott Veldhuizen
Health Systems Research and Consulting Unit, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Can J Psychiatry 52:256-9. 2007..However, performance of the K6 may vary for individual disorders or combinations of disorders. In this report, we examine the ability of the K6 to detect disorders among respondents in different diagnostic categories...
A randomized trial of dialectical behavior therapy versus general psychiatric management for borderline personality disorderShelley F McMain
Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, Canada
Am J Psychiatry 166:1365-74. 2009....
The social epidemiology of affective and anxiety disorders in later life in CanadaJohn Cairney
Health Systems Research and Consulting Unit, Centre for Addiction and Mental Health, Toronto, Ontario
Can J Psychiatry 53:104-11. 2008..To examine the association between markers of social position and psychiatric disorder among older adults, and test whether social support mediates the association between social position and psychiatric disorder in this population...
Long-term prognosis in children with neonatal seizures: a population-based studyGabriel M Ronen
Department of Pediatrics, Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
Neurology 69:1816-22. 2007..To examine outcome and explore for prognostic markers in a cohort <10 years following neonatal seizures...
Early identification and incidence of mild TBI in OntarioWon Hyung A Ryu
Kunin Lunenfeld Applied Research Unit, Baycrest, Toronto, Ontario, Canada
Can J Neurol Sci 36:429-35. 2009..1) To examine the variability in diagnosis of mild traumatic brain injury (mTBI) in primary care relative to that of an expert reviewer; and (2) to determine the incidence rate of mTBI in Ontario, Canada...
The effect of depression on heart rate variability during pregnancy. A naturalistic studyAlison K Shea
CIHR Program, Maternal Adversity, Vulnerability and Neurodevelopment, Hamiltion, ON, Canada
Clin Auton Res 18:203-12. 2008..Women taking AD medication showed some improvement in HRV measures. These data suggest that psychophysiological changes occur in women experiencing depression during pregnancy...
Factor structure of the Multnomah Community Ability Scale--longitudinal analysisDiego G Bassani
Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Psychiatry Res 167:178-89. 2009..Alternative interpretations for the tool and suggestions for the use of its items as an index that measures aspects of disability are proposed...
Exploring the feasibility of videoconference delivery of a self-management program to rural participants with strokeDenise M Taylor
Neurology Services, St Joseph s Care Group, Thunder Bay, Ontario, Canada
Telemed J E Health 15:646-54. 2009..This form of delivery is associated with improvements in goal achievement, mood, balance, and endurance, and is well received by all participants...
Evaluation of 2 measures of psychological distress as screeners for depression in the general populationJohn Cairney
Health Systems Research and Consulting Unit, Centre for Addiction and Mental Health, Toronto, Ontario
Can J Psychiatry 52:111-20. 2007..In this paper, we evaluate 2 measures of psychological distress (the Kessler 6- and 10-Item Psychological Distress Scales [K6 and K10]) as potential screening instruments for depression...
Demonstrating adherence to guidelines for the treatment of patients with borderline personality disorderNathan J Kolla
Resident, Department of Psychiatry, University of Toronto, Toronto, Ontario
Can J Psychiatry 54:181-9. 2009....
Physical activity and depression in older adultsDavid L Streiner
Kunin-Lunenfeld Applied Research Unit, Toronto, Ontario, Canada
Clin J Sport Med 13:274. 2003
Stroke survivors' behavioral and psychologic symptoms are associated with informal caregivers' experiences of depressionJill I Cameron
Toronto Rehabilitation Institute, University of Toronto, ON, Canada
Arch Phys Med Rehabil 87:177-83. 2006..These results can assist rehabilitation professionals to identify informal care providers who are at greater risk of experiencing emotional distress and, therefore, may benefit from intervention...
Interrater reliability of measurements of comorbid illness should be reportedStephen F Hall
Department of Otolaryngology, Queen s University, and Division of Cancer Care and Epidemiology, Queen s Cancer Research Institute, Queen s University, Kingston, Ontario, Canada
J Clin Epidemiol 59:926-33. 2006....
Age-related variables in childhood epilepsy: how do they relate to each other and to quality of life?Lindsay Manor
McMaster University Hamilton, Ontario, Canada
Epilepsy Behav 26:71-4. 2013..22-0.35). Correlation with QOL was clinically non-significant. These variables appear to measure the same phenomenon only in children with early epilepsy onset (<4 years) and explain little variance in QOL...
Impact of self-esteem on the oral-health-related quality of life of children with malocclusionShoroog Agou
Faculty of Dentistry, University of Toronto, Toronto, Ontario, Canada
Am J Orthod Dentofacial Orthop 134:484-9. 2008..The purpose of this study was to examine the relationship between self-esteem and oral-health-related quality of life (OHRQoL) in a sample of children seeking orthodontic treatment in Toronto, Ontario, Canada...
Reader's guide to critical appraisal of cohort studies: 1. Role and designPaula A Rochon
Kunin-Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Toronto, ON, Canada
BMJ 330:895-7. 2005
School-age outcomes in children who were extremely low birth weight from four international population-based cohortsSaroj Saigal
Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
Pediatrics 112:943-50. 2003..The aim of this study was to determine whether learning and school problems in extremely low birth weight (ELBW) and reference children differ between cohorts in different countries...
Prevalence and correlates of agoraphobia in older adultsLaura McCabe
Health Systems Research and Consulting Unit, Centre for Addiction and Mental Health, Department of Psychiatry, University of Toronto Ontario, Canada
Am J Geriatr Psychiatry 14:515-22. 2006..However, little is known about the nature of this disorder in the elderly population. The purpose of this study was to identify risk factors, illness characteristics, and comorbidity of agoraphobia in the elderly...
MRI-based neuroanatomical predictors of dysphagia after acute ischemic stroke: a systematic review and meta-analysisHeather L Flowers
Department of Speech Language Pathology, University of Toronto, Toronto, ON, Canada
Cerebrovasc Dis 32:1-10. 2011..Considering that the incidence of dysphagia is as high as 55% following acute stroke, we undertook a systematic review of the literature to identify lesion sites that predict its presence after acute ischemic stroke...
A measure of quality of life after abdominal surgeryDavid R Urbach
Department of Surgery and Health, University of Toronto, Toronto, ON, Canada
Qual Life Res 15:1053-61. 2006..To develop a reliable and valid measure of short-term quality of life after abdominal surgery...
An appraisal of the psychometric properties of the Clinician version of the Apathy Evaluation Scale (AES-C)Diana E Clarke
Toronto Rehabilitation Institute and Department of Psychiatry, Baycrest Centre for Geriatric Care, Canada
Int J Methods Psychiatr Res 16:97-110. 2007..In conclusion, the AES-C is a reliable and valid measure for the characterization and quantification of apathy...
Mine is bigger than yours: measures of effect size in researchDavid L Streiner
St Joseph s Health Care, Hamilton, ON, Canada
Chest 141:595-8. 2012..This article explains these various indices of effect sizes-how they are calculated, what they mean, and how they are interpreted...
Using relative improvement over chance (RIOC) to examine agreement between tests: three case examples using studies of developmental coordination disorder (DCD) in childrenJohn Cairney
Department of Family Medicine, Offord Centre for Child Studies and the CanChild Centre for Childhood Disability Research, McMaster University, Hamilton, ON, Canada
Res Dev Disabil 32:87-92. 2011..The introduction of this statistic in the area of developmental disabilities research is encouraged...
Benzodiazepine use and driving: a meta-analysisMark J Rapoport
Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
J Clin Psychiatry 70:663-73. 2009..The purpose of the present study was to examine the experimental and epidemiologic evidence linking benzodiazepine use to driving impairment...
Stability of maternal preferences for pediatric health states in the perinatal period and 1 year laterSaroj Saigal
Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
Arch Pediatr Adolesc Med 157:261-9. 2003..However, stability of parental preferences for future pediatric health states is unknown during the antenatal and neonatal periods and infancy...
Correction for multiple testing: is there a resolution?David L Streiner
Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada
Chest 140:16-8. 2011..In this article, we offer recommendations about when they should and should not be brought into play...
The effect of depression, anxiety and early life trauma on the cortisol awakening response during pregnancy: preliminary resultsAlison K Shea
CIHR Program Maternal Adversity, Vulnerability and Neurodevelopment, Hamilton, Ontario, Canada
Psychoneuroendocrinology 32:1013-20. 2007..The CAR may provide important information about the maternal HPA axis during pregnancy and warrants further investigation in larger cohorts...
Do hospital E-codes consistently capture suicidal behaviour?Anne E Rhodes
The Suicide Studies Unit, St Michael s Hospital, 30 Bond Street, Toronto, Ontario, Canada M5B 1W8
Chronic Dis Can 23:139-45. 2002..Estimating the prevalence of admissions for suicidal behaviour using hospital separation data is of questionable validity, particularly among older age groups...
Test-retest reliability, validity, and sensitivity of the Chedoke arm and hand activity inventory: a new measure of upper-limb function for survivors of strokeSusan R Barreca
Orthopedic and Rehabilitation Services, Hamilton Health Sciences, Hamilton, ON, Canada
Arch Phys Med Rehabil 86:1616-22. 2005....
Relation between randomized controlled trials published in leading general medical journals and the global burden of diseasePaula A Rochon
Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, Toronto, Ontario M6A 2E1, Canada
CMAJ 170:1673-7. 2004..We evaluated the relation between the global burden of disease and conditions or diseases studied in randomized controlled trials (RCTs) published in general medical journals...
Alternatives to placebo-controlled trialsDavid L Streiner
Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada
Can J Neurol Sci 34:S37-41. 2007..This paper briefly considers the ethics of placebo, and conditions are stated under which such studies can be conducted...
Health-related quality of life in children with epilepsy: development and validation of self-report and parent proxy measuresGabriel M Ronen
Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada
Epilepsia 44:598-612. 2003....
Antidepressants and the risk of breast cancerPaul A Kurdyak
Department of Psychiatry, University of Toronto, Toronto, Ontario
Can J Psychiatry 47:966-70. 2002..The authors of the 2 papers recommend switching or avoiding the antidepressants implicated in their studies...
The Toronto Bedside Swallowing Screening Test (TOR-BSST): development and validation of a dysphagia screening tool for patients with strokeRosemary Martino
Department of Speech Language Pathology, University of Toronto, Toronto, Ontario, Canada
Stroke 40:555-61. 2009..We designed and validated a new bedside dysphagia screening tool-the Toronto Bedside Swallowing Screening Test (TOR-BSST) for stroke survivors in acute and rehabilitative settings...
A prescribing cascade involving cholinesterase inhibitors and anticholinergic drugsSudeep S Gill
Institute for Clinical Evaluative Sciences, Toronto, Ontario
Arch Intern Med 165:808-13. 2005..We present a new example of the prescribing cascade involving cholinesterase inhibitors and anticholinergic drugs used to manage urinary incontinence...
Strategic subcortical hyperintensities in cholinergic pathways and executive function decline in treated Alzheimer patientsPearl Behl
Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, 160 Russell Jarvis Drive, Toronto, Ontario, Canada
Arch Neurol 64:266-72. 2007....
A comparison of Canadian medical students from rural and non-rural backgroundsJeff C Kwong
Community Medicine, University of Toronto, Toronto, Ontario M5S 1A8, Canada
Can J Rural Med 10:36-42. 2005..Medical schools should examine and address barriers to admission of rural students and they should consider directing more financial resources toward this financially vulnerable group...
Comparison of review articles published in peer-reviewed and throwaway journalsPaula A Rochon
Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Department of Medicine, University of Toronto, Toronto, Ontario, Canada M6A 2E1
JAMA 287:2853-6. 2002..To compare the quality, presentation, readability, and clinical relevance of review articles published in peer-reviewed and "throwaway" journals...
Quality of life among Brazilian children with epilepsy: validation of a parent proxy instrument (QVCE-50)Heber de Souza Maia Filho
Department of Maternal and Child Health, Faculdade de Medicina de PetrĂ³polis Postgraduation Doctorate, Institute of Psychiatry Universidade Federal do Rio de Janeiro CNPq scholarship, Brazil
Seizure 16:324-9. 2007..Items were scored on a four point scale. Domains were equally weighted using percent scores. The questionnaire ends with a quality of life scale scored 0-10 and a space for free observations...
Health-related quality of life of children with epilepsy in Hong Kong: how does it compare with that of youth with epilepsy in Canada?Winnie K L Yam
Department of Paediatrics and Adolescent Medicine, Alice Ho Miu Ling Hospital and North District Hospital, Hong Kong SAR, China
Epilepsy Behav 12:419-26. 2008..A second interest was to determine agreement between proxy reports and self-ratings among children with epilepsy in Hong Kong, compare these with findings in Canada, and identify factors that influence the concordance...
Exploring the association between atypical neuroleptic agents and diabetes mellitus in older adultsMahyar Etminan
Department of Clinical Epidemiology, Royal Victoria Hospital, McGill University, Montreal, Quebec, Canada
Pharmacotherapy 23:1411-5. 2003..To explore the suggested association between atypical neuroleptic use and the development of diabetes mellitus, with a focus on older adults...
Relation of blood counts during clozapine treatment to serum concentrations of clozapine and nor-clozapineL Kola Oyewumi
Queen s University, Kingston, Ontario
Can J Psychiatry 47:257-61. 2002..To determine the relation between serum clozapine and nor-clozapine levels and blood cell counts during clozapine treatment...
Apathy in dementia: an examination of the psychometric properties of the apathy evaluation scaleDiana E Clarke
Department of Mental Health, Johns Hopkins School of Public Health, Room 802, 624 North Broadway, Baltimore, MD 21205, USA
J Neuropsychiatry Clin Neurosci 19:57-64. 2007..However, from a diagnostic point of view, the AES-I provided the greatest sensitivity and the strongest positive and negative predictive values. Generally, the AES-S performed poorly compared with the AES-C and AES-I...
Health-related quality of life in youth with epilepsy: theoretical model for clinicians and researchers. Part I: the role of epilepsy and co-morbidityLucyna M Lach
School of Social Work McGill University, 3506 University St, Montreal, PQ, Canada
Qual Life Res 15:1161-71. 2006..The purpose of this review is to identify what is meant by HRQL as well as outline the theoretical and empirical basis for what it is about epilepsy, co-morbidity, and its treatment that we believe make a difference to HRQL...
Do selective serotonin reuptake inhibitors cause suicide? Let's keep it in perspectiveIsaac Sakinofsky
BMJ 330:1149; author reply 1150. 2005
Characteristics of first-year students in Canadian medical schoolsIrfan A Dhalla
University of Toronto, Ont
CMAJ 166:1029-35. 2002..6% of the respondents had a physician parent. INTERPRETATION: Canadian medical students differ significantly from the general population, particularly with regard to ethnic background and socioeconomic status...
Sample size in clinical research: when is enough enough?David L Streiner
J Pers Assess 87:259-60. 2006
Qualitative research in psychiatryDavid L Streiner
Can J Psychiatry 53:135-6. 2008
Measuring comorbidity in patients with head and neck cancerStephen F Hall
Department of Otolaryngology, Queen s University, Kingston, Ontario, Canada
Laryngoscope 112:1988-96. 2002..Comorbidities are diseases or conditions that coexist with a disease of interest. The importance of comorbidities is that they can alter treatment decisions, change resource utilization, and confound the results of survival analysis...
Psychiatric epidemiology in Canada and the CCHS studyDavid L Streiner
Can J Psychiatry 50:571-2. 2005
Editorial: introduction to the article on "dual scaling"David L Streiner
J Pers Assess 85:207-8. 2005
Program structure and continuity of mental health careJanet Durbin
Department of Psychiatry, University of Toronto, Ontario, Canada
Can J Nurs Res 36:12-37. 2004..The association between each of the other 7 program features and continuity was not significant. Possible explanations for this finding are explored...
Editorial: measuring individual level changeDavid L Streiner
J Pers Assess 82:48-9. 2004
Sex differences in first-year students at Canadian medical schoolsAndrea E Waddell
University of Toronto
J Am Med Womens Assoc 59:25-9. 2004..These sex differences need to be investigated further, as they could have implications for health policy...
Effects of rising tuition fees on medical school class composition and financial outlookJeff C Kwong
University of Toronto, Ont
CMAJ 166:1023-8. 2002....
