Research Topics
| S KleinmanSummaryCountry: Canada Publications
| Collaborators
|
Detail Information
Publications
The National Heart, Lung, and Blood Institute retrovirus epidemiology donor studies (Retrovirus Epidemiology Donor Study and Retrovirus Epidemiology Donor Study-II): twenty years of research to advance blood product safety and availabilitySteven Kleinman
Department of Pathology, University of British Columbia, Victoria, British Columbia, Canada
Transfus Med Rev 26:281-304, 304.e1-2. 2012....
The Leukocyte Antibody Prevalence Study-II (LAPS-II): a retrospective cohort study of transfusion-related acute lung injury in recipients of high-plasma-volume human leukocyte antigen antibody-positive or -negative componentsSteven H Kleinman
Westat, Inc, Rockville, Maryland, USA
Transfusion 51:2078-91. 2011..We used a multicenter retrospective cohort study design to evaluate whether human leukocyte antigen (HLA) antibody donor screening would reduce the risk of transfusion-related acute lung injury (TRALI) or possible TRALI...
A national survey of transfusion-related acute lung injury risk reduction policies for platelets and plasma in the United StatesSteven Kleinman
AABB, Bethesda, Maryland, USA
Transfusion 50:1312-21. 2010..Little information exists on the specific transfusion-related acute lung injury (TRALI) risk reduction practices used by multiple blood collecting institutions in the United States...
A linked donor-recipient study to evaluate parvovirus B19 transmission by blood component transfusionSteven H Kleinman
Westat Inc, Rockville, MD, USA
Blood 114:3677-83. 2009..These data do not support the need to routinely screen blood donations with a sensitive B19V DNA nucleic acid assay...
Survival after transfusion as assessed in a large multistate US cohortSteven Kleinman
Kleinman Biomedical Research, 1281 Rockcrest Avenue, Victoria, British Columbia V9A 4W4, Canada
Transfusion 44:386-90. 2004..The only survival and mortality data on a general population of transfused patients in the United States is more than two decades old. More contemporary data are needed to reflect more current patient populations and transfusion practices...
The donor notification process from the donor's perspectiveSteven Kleinman
Westat, Rockville, Maryland, USA
Transfusion 44:658-66. 2004..Despite large numbers of blood donors being notified of abnormal infectious disease screening results, there has been little scientific study of the effects of this process...
The impact of discontinuation of 7-day storage of apheresis platelets (PASSPORT) on recipient safety: an illustration of the need for proper risk assessmentsSteven Kleinman
University of British Columbia, Vancouver, British Columbia, Canada
Transfusion 49:903-12. 2009..The impact of this discontinuation on recipient safety was explored using mathematical modeling...
Initiatives to improve blood donor screeningS Kleinman
Professor of Clinical Pathology, University of British Columbia, Vancouver, BC, Canada
Dev Biol (Basel) 120:67-75. 2005
False-positive HIV-1 test results in a low-risk screening setting of voluntary blood donation. Retrovirus Epidemiology Donor StudyS Kleinman
Westat Inc, Rockville, MD, USA
JAMA 280:1080-5. 1998..Persons at risk of human immunodeficiency virus 1 (HIV-1) infection, have been classified incorrectly as HIV infected because of Western blot results, but the frequency of false-positive Western blot results is unknown...
Comparison of demographic and donation profiles and transfusion-transmissible disease markers and risk rates in previously transfused and nontransfused blood donorsB Wang
Westat, Rockville, Maryland 20850, USA
Transfusion 44:1243-51. 2004..Little is known, however, about the impact of indefinite deferral of transfused donors on blood safety and availability in the US...
Hepatitis G virus biology, epidemiology, and clinical manifestations: Implications for blood safetyS Kleinman
University of British Columbia, Vancouver, British Columbia, Canada
Transfus Med Rev 15:201-12. 2001..Because the data do not indicate any pathologic effects of HGV, it is not appropriate to screen the blood supply for HGV RNA...
Does prevalence of transfusion-transmissible viral infection reflect corresponding incidence in United States blood donors?Baoguang Wang
Westat, Rockville, Maryland 20850, USA
Transfusion 45:1089-96. 2005..Prevalence, however, is readily available. Understanding whether prevalence reflects corresponding incidence may help blood centers monitor disease risks...
Correlates of hepatitis C virus (HCV) RNA negativity among HCV-seropositive blood donorsMichael P Busch
Blood Systems Research Institute, San Francisco, California 94118, USA
Transfusion 46:469-75. 2006..Factors associated with resolution of viremia are not well defined. Implementation of routine nucleic acid testing (NAT) of blood donors has yielded a large data set for analysis of demographic correlates of resolved viremia...
A perspective on transfusion-related acute lung injury two years after the Canadian Consensus ConferenceSteven Kleinman
Transfusion 46:1465-8. 2006
Promoting recognition and prevention of transfusion-related acute lung injurySteven Kleinman
AABB (American Association of Blood Banks, Bethesda, MD 20814-2749, USA
Crit Care Nurse 27:49-53. 2007
The development of West Nile virus safety policies by Canadian blood services: guiding principles and a comparison between Canada and the United StatesEleftherios C Vamvakas
Canadian Blood Services; Department of Pathology and Laboratory Medicine, University of Ottawa Faculty of Medicine, ON, Canada
Transfus Med Rev 20:97-109. 2006..This review discusses the guiding principles affecting CBS policy development and compares CBS WNV safety policies to policies adopted in the United States...
Performance characteristics of the Food and Drug Administration-licensed Roche Cobas TaqScreen West Nile virus assayAnuradha Pai
From Roche Molecular Systems, Pleasanton, California 94588, USA
Transfusion 48:2184-9. 2008..A series of studies established the performance characteristics of the assay and test system before FDA licensure...
Toward an understanding of transfusion-related acute lung injury: statement of a consensus panelSteven Kleinman
Kleinman Biomedical Research, Victoria, British Columbia, Canada
Transfusion 44:1774-89. 2004
Transfusion transmission of West Nile virus: a merging of historical and contemporary perspectivesF Blaine Hollinger
Baylor College of Medicine, Houston, Texas, USA
Transfusion 43:992-7. 2003
Research, monitoring, and policy issues related to emerging pathogensSteven Kleinman
U. British Columbia, Vancouver, BC, Canada
Vox Sang 83:351-4. 2002
The 2003 West Nile virus United States epidemic: the America's Blood Centers experienceSteven Kleinman
Westat, Rockville, Maryland, USA
Transfusion 45:469-79. 2005..This study demonstrates that a national collaborative effort facilitates timely surveillance of blood donor infectious disease prevalence rates...
AABB survey of transfusion-related acute lung injury policies and practices in the United StatesPatricia Kopko
Histocompatibility Laboratory, BloodSource, Sacramento, California, USA
Transfusion 47:1679-85. 2007..Policies and practices with regard to transfusion-related acute lung injury (TRALI) diagnosis, laboratory investigation of TRALI cases, and donor deferral and donor management are not standardized...
