Paul Khairy

Summary

Country: Canada

Publications

  1. ncbi request reprint Programmed ventricular stimulation for risk stratification in patients with tetralogy of Fallot: a Bayesian perspective
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, Montreal, QC, Canada
    Nat Clin Pract Cardiovasc Med 4:292-3. 2007
  2. doi request reprint Ventricular proarrhythmic effects of atrial fibrillation are modulated by depolarization and repolarization anomalies in patients with left ventricular dysfunction
    Kristina Lemola
    Electrophysiology Service, Montreal Heart Institute, University of Montreal, Montreal, Canada
    Pacing Clin Electrophysiol 32:99-105. 2009
  3. doi request reprint Looking ahead: clinical trial design in adult congenital heart disease
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, 5000 Belanger St E, Montreal, QC, H1T 1C8, Canada
    Future Cardiol 8:297-304. 2012
  4. doi request reprint Risk stratification in surgically repaired tetralogy of Fallot
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, QC, Canada
    Expert Rev Cardiovasc Ther 7:755-62. 2009
  5. ncbi request reprint Wolff-Parkinson-white syndrome in d-transposition of the great arteries and mustard baffle
    Paul Khairy
    Electrophysiology Service and Adult Congenital Heart Center, Montreal Heart Institute, Montreal, Canada
    Heart Rhythm 3:853-6. 2006
  6. ncbi request reprint Univentricular heart
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, 5000 Belanger St, Montreal, Quebec, H1T 1C8, Canada
    Circulation 115:800-12. 2007
  7. ncbi request reprint Transvenous pacing leads and systemic thromboemboli in patients with intracardiac shunts: a multicenter study
    Paul Khairy
    Adult Congenital Heart and Electrophysiology Services, Montreal Heart Institute, Montreal, Canada
    Circulation 113:2391-7. 2006
  8. doi request reprint Implantable cardioverter-defibrillators in tetralogy of Fallot
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, 5000 Belanger St, Montreal, Quebec, Canada H1T 1C8
    Circulation 117:363-70. 2008
  9. ncbi request reprint Partial atrioventricular canal defect with inverted atrioventricular nodal input into an inferiorly displaced atrioventricular node
    Paul Khairy
    Electrophysiology Service and Adult Congenital Heart Center, Montreal Heart Institute, Montreal, Quebec, Canada
    Heart Rhythm 4:355-8. 2007
  10. ncbi request reprint Laser lead extraction in adult congenital heart disease
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, Montreal, QC, Canada
    J Cardiovasc Electrophysiol 18:507-11. 2007

Detail Information

Publications100

  1. ncbi request reprint Programmed ventricular stimulation for risk stratification in patients with tetralogy of Fallot: a Bayesian perspective
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, Montreal, QC, Canada
    Nat Clin Pract Cardiovasc Med 4:292-3. 2007
  2. doi request reprint Ventricular proarrhythmic effects of atrial fibrillation are modulated by depolarization and repolarization anomalies in patients with left ventricular dysfunction
    Kristina Lemola
    Electrophysiology Service, Montreal Heart Institute, University of Montreal, Montreal, Canada
    Pacing Clin Electrophysiol 32:99-105. 2009
    ..We assessed whether AF predicts appropriate implantable cardioverter-defibrillator (ICD) shocks in patients with left ventricular dysfunction and explored modulators of risk...
  3. doi request reprint Looking ahead: clinical trial design in adult congenital heart disease
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, 5000 Belanger St E, Montreal, QC, H1T 1C8, Canada
    Future Cardiol 8:297-304. 2012
    ..In looking ahead, examples of creative methodological solutions to maximizing the efficiency of clinical trials for rare diseases are discussed, including Bayesian analyses, outcome-adaptive randomization and internal pilot studies...
  4. doi request reprint Risk stratification in surgically repaired tetralogy of Fallot
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, QC, Canada
    Expert Rev Cardiovasc Ther 7:755-62. 2009
    ....
  5. ncbi request reprint Wolff-Parkinson-white syndrome in d-transposition of the great arteries and mustard baffle
    Paul Khairy
    Electrophysiology Service and Adult Congenital Heart Center, Montreal Heart Institute, Montreal, Canada
    Heart Rhythm 3:853-6. 2006
  6. ncbi request reprint Univentricular heart
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, 5000 Belanger St, Montreal, Quebec, H1T 1C8, Canada
    Circulation 115:800-12. 2007
    ..Although the present report touches on issues applicable to neonates and children with univentricular hearts, the focus is on information of interest and relevance to the adult cardiologist...
  7. ncbi request reprint Transvenous pacing leads and systemic thromboemboli in patients with intracardiac shunts: a multicenter study
    Paul Khairy
    Adult Congenital Heart and Electrophysiology Services, Montreal Heart Institute, Montreal, Canada
    Circulation 113:2391-7. 2006
    ..The risk of systemic thromboemboli associated with transvenous leads in the presence of an intracardiac shunt is currently unknown...
  8. doi request reprint Implantable cardioverter-defibrillators in tetralogy of Fallot
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, 5000 Belanger St, Montreal, Quebec, Canada H1T 1C8
    Circulation 117:363-70. 2008
    ..Tetralogy of Fallot is the most common form of congenital heart disease in implantable cardioverter-defibrillator (ICD) recipients, yet little is known about the value of ICDs in this patient population...
  9. ncbi request reprint Partial atrioventricular canal defect with inverted atrioventricular nodal input into an inferiorly displaced atrioventricular node
    Paul Khairy
    Electrophysiology Service and Adult Congenital Heart Center, Montreal Heart Institute, Montreal, Quebec, Canada
    Heart Rhythm 4:355-8. 2007
  10. ncbi request reprint Laser lead extraction in adult congenital heart disease
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, Montreal, QC, Canada
    J Cardiovasc Electrophysiol 18:507-11. 2007
    ..We sought to assess the safety and feasibility of laser lead extraction in ACHD...
  11. doi request reprint Arrhythmia burden in adults with surgically repaired tetralogy of Fallot: a multi-institutional study
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, University of Montreal, Montreal, Quebec, Canada
    Circulation 122:868-75. 2010
    ..The arrhythmia burden in tetralogy of Fallot, types of arrhythmias encountered, and risk profile may change as the population ages...
  12. ncbi request reprint Clinical use of electrocardiography in adults with congenital heart disease
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, 5000 Belanger St, Montreal, Quebec, Canada
    Circulation 116:2734-46. 2007
  13. doi request reprint Enlargement of catheter ablation lesions in infant hearts with cryothermal versus radiofrequency energy: an animal study
    Paul Khairy
    Electrophysiology Service and Research Center, Montreal Heart Institute, Universite de Montreal, Canada
    Circ Arrhythm Electrophysiol 4:211-7. 2011
    ..It remains unknown whether cryothermal ablation lesions display a similar pattern of growth...
  14. doi request reprint Programming ICDs in the Modern Era beyond Out-of-the Box Settings
    Fadi Mansour
    Electrophysiology Services, Centre Hospitalier Universite de Montreal, Montreal, Canada
    Pacing Clin Electrophysiol 34:506-20. 2011
    ..We discuss the benefits and pitfalls of strategies such as high cutoff rates, longer detections times, antitachycardia pacing, and discriminators in reducing the incidence of inappropriate shocks and offer practical programming tips...
  15. doi request reprint Sudden death and defibrillators in transposition of the great arteries with intra-atrial baffles: a multicenter study
    Paul Khairy
    Canadian Adult Congenital Heart Network, Montreal, Quebec, Canada
    Circ Arrhythm Electrophysiol 1:250-7. 2008
    ..Little is known about mechanisms of sudden death and the role of implantable cardioverter defibrillators...
  16. ncbi request reprint Arrhythmias in adult congenital heart disease
    Paul Khairy
    Electrophysiology and Adult Congenital Heart Disease, Montreal Heart Institute, Montreal, QC H1T 1C8, Canada
    Expert Rev Cardiovasc Ther 4:83-95. 2006
    ..This review highlights the various types of brady- and tachyarrhythmias encountered in the more common forms of adult congenital heart disease and explores prognostic implications and therapeutic options...
  17. ncbi request reprint A novel hybrid transcatheter ablation system that combines radiofrequency and cryoenergy
    Paul Khairy
    Department of Medicine and Research Center, Montreal Heart Institute, Montreal, Canada
    J Cardiovasc Electrophysiol 19:188-93. 2008
    ..There are numerous theoretical advantages to engineering a system capable of delivering both energy forms...
  18. doi request reprint Transcatheter ablation via a sternotomy approach as a hybrid procedure in a univentricular heart
    Paul Khairy
    Department of Pediatric Cardiology, Hopital Sainte Justine, Montreal, Canada
    Pacing Clin Electrophysiol 31:639-40. 2008
    ..A recalcitrant accessory pathway was successfully ablated in a patient with hemodynamically unstable supraventricular tachycardia and an extracadiac Fontan for hypoplastic left heart syndrome...
  19. doi request reprint Morphometric ablation lesion characteristics comparing 4, 6, and 8 mm electrode-tip cryocatheters
    Paul Khairy
    Electrophysiology Service, Montreal Heart Institute, University of Montreal, Montreal, Quebec, Canada
    J Cardiovasc Electrophysiol 19:1203-7. 2008
    ..Surface areas and volumes may be particularly sensitive to catheter tip-to-tissue contact angles with larger electrodes, as reflected by greater variability with 8 mm tips...
  20. doi request reprint EP challenges in adult congenital heart disease
    Paul Khairy
    Adult Congenital Heart Center and Electrophysiology Service, Montreal Heart Institute, University of Montreal, Canada
    Heart Rhythm 5:1464-72. 2008
    ..The objective of this review is to highlight commonly confronted arrhythmia issues and themes, discuss particular challenges, review recent relevant literature, and summarize current management trends...
  21. ncbi request reprint Laser lead extraction: predictors of success and complications
    Jean Francois Roux
    Electrophysiology Service, Department of Cardiology, Montreal Heart Institute, Montreal, Canada
    Pacing Clin Electrophysiol 30:214-20. 2007
    ..Paralleling the rise in pacemaker and defibrillator implantations, lead extraction procedures are increasingly required. Concerns regarding failure and complications remain...
  22. doi request reprint Histopathological effects and evolution of transvenous β-radiation applications in right and left atria: an animal study
    Frederic Franceschi
    Electrophysiology Service, Montreal Heart Institute, Universite de Montreal, 5000 Belanger St E, Montreal, Quebec, Canada
    Europace 14:745-51. 2012
    ..The purpose of this study was to characterize pathological aspects of cardiac lesions induced by β-radiation in an animal model at various stages of evolution and in response to different dose exposures...
  23. doi request reprint Cryoablation outcomes for AV nodal reentrant tachycardia comparing 4-mm versus 6-mm electrode-tip catheters
    Lena Rivard
    Electrophysiology Service, Montreal Heart Institute, Montreal, Quebec, Canada
    Heart Rhythm 5:230-4. 2008
    ..Cryoablation is increasingly used to treat atrioventricular nodal reentrant tachycardia (AVNRT). It is unknown whether larger electrode-tip cryocatheters improve outcomes without compromising safety...
  24. doi request reprint Tetralogy of Fallot and aortic root disease
    Laurianne Le Gloan
    The Montreal Heart Institute Adult Congenital Center, Universite de Montreal, 5000 Belanger Street East, Montreal, QC, H1T 1C8, Canada
    Expert Rev Cardiovasc Ther 11:233-8. 2013
    ....
  25. doi request reprint Anxiety sensitivity moderates prognostic importance of rhythm-control versus rate-control strategies in patients with atrial fibrillation and congestive heart failure: insights from the Atrial Fibrillation and Congestive Heart Failure Trial
    Nancy Frasure-Smith
    Heart Institute Research Centre, 5000 Belanger, Montreal, Quebec, Canada H1T 1C8
    Circ Heart Fail 5:322-30. 2012
    ..We assessed whether AS is associated with outcomes of rhythm-control versus rate-control in congestive heart failure (CHF) patients with AF...
  26. ncbi request reprint Atrial fibrillation and congestive heart failure
    Denis Roy
    Montreal Heart Institute and Department of Medicine, Universite de Montreal, Montreal, Quebec, Canada
    Curr Opin Cardiol 24:29-34. 2009
    ....
  27. doi request reprint Pulmonary vein isolation for the treatment of atrial fibrillation: past, present and future
    Jean Benoit le Polain de Waroux
    Montreal Heart Institute, Universite de Montreal, Canada
    Future Cardiol 6:51-66. 2010
    ..Pulmonary vein isolation has emerged as an effective treatment in selected patients. In this paper, the past and present roles of pulmonary vein isolation are described and the future developments of this technique are explored...
  28. ncbi request reprint Atrial fibrillation: basic and clinical research at the Montreal Heart Institute
    Denis Roy
    Department of Medicine and Research Centre, Montreal Heart Institute, Faculty of Medicine, University of Montreal, Quebec
    Can J Cardiol 21:1091-6. 2005
    ..Future directions at the Montreal Heart Institute are also briefly addressed...
  29. doi request reprint Quality of life and functional capacity in patients with atrial fibrillation and congestive heart failure
    Irina Suman-Horduna
    Montreal Heart Institute and Montreal Heart Institute Coordinating Center, Universite de Montreal, Montreal, Quebec, Canada
    J Am Coll Cardiol 61:455-60. 2013
    ..This study sought to assess the impact of rhythm- versus rate-control treatment strategies and of underlying rhythm on quality of life and functional capacity in patients with atrial fibrillation (AF) and congestive heart failure (CHF)...
  30. ncbi request reprint Mineralocorticoid receptor antagonists and cardiovascular mortality in patients with atrial fibrillation and left ventricular dysfunction: insights from the Atrial Fibrillation and Congestive Heart Failure Trial
    Eileen O'Meara
    Montreal Heart Institute, Montreal Heart Institute Coordinating Center, and Université de Montréal, Montreal, QC, Canada
    Circ Heart Fail 5:586-93. 2012
    ..Our primary objective was to assess the impact of mineralocorticoid receptor antagonists on cardiovascular mortality in patients with AF and HF enrolled in the Atrial Fibrillation and Congestive Heart Failure (AF-CHF) trial...
  31. doi request reprint Left ventricular versus simultaneous biventricular pacing in patients with heart failure and a QRS complex ≥120 milliseconds
    Bernard Thibault
    Montreal Heart Institute, 5000 Belanger St, Montreal, QC, Canada H1T 1C8
    Circulation 124:2874-81. 2011
    ..Left ventricular (LV) pacing alone may theoretically avoid deleterious effects of right ventricular pacing...
  32. ncbi request reprint Lower incidence of thrombus formation with cryoenergy versus radiofrequency catheter ablation
    Paul Khairy
    Department of Electrophysiology, Montreal Heart Institute, Quebec, Canada
    Circulation 107:2045-50. 2003
    ..The objective of this study was to compare the incidence and characteristics of thrombi complicating RF and cryoenergy ablation, a novel technology for the catheter-based treatment of arrhythmias...
  33. doi request reprint Fontan circulation: success or failure?
    Blandine Mondesert
    Montreal Heart Institute Adult Congenital Center, Universite de Montreal, Montreal, Quebec, Canada
    Can J Cardiol 29:811-20. 2013
    ..Multicentre and multidisciplinary efforts to improve the density and depth of experiences might lead to a better appreciation for, and management of, Fontan failure and its ramifications. ..
  34. doi request reprint Aortic root dilatation in adults with surgically repaired tetralogy of fallot: a multicenter cross-sectional study
    François Pierre Mongeon
    SM, Adult Congenital Heart Center, Montreal Heart Institute, 5000 Belanger St, Montreal, QC, Canada H1T 1C8
    Circulation 127:172-9. 2013
    ..We sought to determine the prevalence and predictors of aortic root dilatation in adults with repaired tetralogy of Fallot...
  35. doi request reprint The biophysics and biomechanics of cryoballoon ablation
    Jason G Andrade
    Electrophysiology Service, Department of Cardiology, Montreal Heart Institute, Universite de Montreal, Montreal, Canada
    Pacing Clin Electrophysiol 35:1162-8. 2012
    ....
  36. doi request reprint Pulmonary arterial hypertension in patients with transcatheter closure of secundum atrial septal defects: a longitudinal study
    Gerald Yong
    Adult Congenital Heart Center, Montreal Heart Institute, University of Montreal, Canada
    Circ Cardiovasc Interv 2:455-62. 2009
    ..Pulmonary arterial hypertension (PAH) may develop in patients with atrial septal defects (ASD); however, little is known about associated risk factors and its evolution after transcatheter ASD closure...
  37. ncbi request reprint Cryothermal slow pathway modification for atrioventricular nodal reentrant tachycardia
    Paul Khairy
    Electrophysiology Service, Montreal Heart Institute, 5000 Belanger St East, Montreal, Quebec, Canada H1T 1C8
    Europace 9:909-14. 2007
    ..persistent dual atrioventricular (AV) nodal physiology with or without echo beats...
  38. ncbi request reprint Cardiac resynchronization therapy in congenital heart disease
    Paul Khairy
    Electrophysiology and Adult Congenital Heart Services, Montreal Heart Institute, Canada
    Int J Cardiol 109:160-8. 2006
    ..Multicenter prospective collaborative efforts are to be encouraged...
  39. ncbi request reprint Shocking truths about implantable cardioverter defibrillator monitoring zones
    Fadi Mansour
    Electrophysiology Service, Montreal Heart Institute, Montreal, Quebec, Canada
    Pacing Clin Electrophysiol 30:1146-8. 2007
    ..In the absence of a monitoring zone, device therapy would not have been expected. We explore the mechanisms by which monitoring zones could potentially contribute to inappropriate ICD therapy and offer trouble-shooting tips...
  40. doi request reprint Cardiac resynchronization therapy in patients with heart failure and a QRS complex <120 milliseconds: the Evaluation of Resynchronization Therapy for Heart Failure (LESSER-EARTH) trial
    Bernard Thibault
    Montreal Heart Institute, Universite de Montreal, Montreal, QB, Canada
    Circulation 127:873-81. 2013
    ..Although the benefits of cardiac resynchronization therapy are well established in selected patients with heart failure and a prolonged QRS duration, salutary effects in patients with narrow QRS complexes remain to be demonstrated...
  41. doi request reprint Atrial fibrillation-associated remodeling does not promote atrial thrombus formation in canine models
    Kunihiro Nishida
    Department of Medicine and Research Center, Montreal Heart Institute and Universite de Montreal, Quebec, Canada
    Circ Arrhythm Electrophysiol 5:1168-75. 2012
    ..This study assessed effects of AF-related remodeling on the atrial thrombogenic milieu by using radiofrequency ablation (RFA) to create a quantifiable prothrombotic nidus...
  42. doi request reprint Canine left ventricle electromechanical behavior under different pacing modes
    Thanh Thuy Vo Thang
    Department of Nuclear Medicine, Montreal Heart Institute, University of Montreal, 5000 Belanger Street, Montreal, Quebec H1T 1C8, Canada
    J Interv Card Electrophysiol 35:11-7. 2012
    ..While several studies have investigated electrical or mechanical determinants of synchronous contraction, few have focused on activation contraction coupling at a macroscopic level...
  43. pmc Pulmonary vein isolation and left atrial catheter ablation using a three-dimensional navigation system for the treatment of atrial fibrillation
    Laurent Macle
    Montreal Heart Institute, Montreal, Canada
    Can J Cardiol 25:e169-72. 2009
    ..Catheter ablation strategies targeting PVs and the posterior LA may be further refined by incorporating technology beyond standard fluoroscopy...
  44. ncbi request reprint Concordance between an electroanatomic mapping system and cardiac MRI in arrhythmogenic right ventricular cardiomyopathy
    Jean Francois Roux
    Electrophysiology Service, Department of Cardiology, Montreal Heart Institute, Montreal, Canada
    Pacing Clin Electrophysiol 29:109-12. 2006
    ..This report describes concordance between cardiac MRI and this novel mapping system in arrhythmogenic RV cardiomyopathy...
  45. doi request reprint Pregnancy in women with Fontan physiology
    Laurianne Le Gloan
    Adult Congenital Heart Center, Montreal Heart Institute, 5000 Belanger St E, Montreal, QC, H1T 1C8, Canada
    Expert Rev Cardiovasc Ther 9:1547-56. 2011
    ..Management issues are addressed, including counseling, anesthetic considerations and the need for multidisciplinary specialized care...
  46. doi request reprint Early recurrence of atrial tachyarrhythmias following radiofrequency catheter ablation of atrial fibrillation
    Jason G Andrade
    Electrophysiology Service, Department of Cardiology, Montreal Heart Institute, Universite de Montreal, Montreal, Canada
    Pacing Clin Electrophysiol 35:106-16. 2012
    ....
  47. doi request reprint Evaluation of resynchronization therapy for heart failure in patients with a QRS duration greater than 120 ms (GREATER-EARTH) trial: rationale, design, and baseline characteristics
    Bernard Thibault
    Montreal Heart Institute and Universite de Montreal, Montreal, Quebec, Canada
    Can J Cardiol 27:779-86. 2011
    ..Despite its demonstrated salutary effects on clinical evolution, left ventricular (LV) function, and overall survival, at least 30% of patients fail to respond to CRT...
  48. doi request reprint Characterization and reproducibility of forearm arterial flow during reactive hyperemia
    Nina Olamaei
    Department of Nuclear Medicine, Montreal Heart Institute and University of Montreal, Montreal, Quebec, Canada
    Physiol Meas 31:763-73. 2010
    ..Basal flow measurements and results of this modeling were reproducible 24 and 27 h later...
  49. ncbi request reprint Pacemaker troubleshooting: when MVP is not the most valuable parameter
    Fadi Mansour
    Electrophysiology Service, Montreal Heart Institute, Montreal, Quebec, Canada
    Heart Rhythm 3:612-4. 2006
  50. ncbi request reprint Prognostic significance of ventricular arrhythmias post-myocardial infarction
    Paul Khairy
    Department of Medicine, Montreal Heart Institute, University of Montreal, Montreal, Quebec, Canada
    Can J Cardiol 19:1393-404. 2003
    ..Inhospital mortality is higher when ventricular fibrillation presents in the acute phase but long term prognosis is not adversely affected...
  51. doi request reprint Clinical assessment of arrhythmias in tetralogy of Fallot
    Laurianne Le Gloan
    Adult Congenital Heart Center, Montreal Heart Institute, University of Montreal, 5000 Belanger St E Montreal, H1T 1C8 QC, Canada
    Expert Rev Cardiovasc Ther 8:189-97. 2010
    ..Current prognostic markers and existing diagnostic tools are discussed, and available therapeutic options are elaborated...
  52. doi request reprint Incidence and significance of early recurrences associated with different ablation strategies for AF: a STAR-AF substudy
    Jason G Andrade
    Montreal Heart Institute and Universite de Montreal, Montreal, Quebec, Canada
    J Cardiovasc Electrophysiol 23:1295-301. 2012
    ..Early recurrences of atrial tachyarrhythmias (ERAT) are common after atrial fibrillation (AF) ablation, and predict late recurrences (LR). We sought to determine the impact of different ablation strategies on ERAT and LR...
  53. doi request reprint Pulmonary vein isolation using a second-generation cryoballoon catheter: a randomized comparison of ablation duration and method of deflation
    Jason G Andrade
    Electrophysiology Service, Department of Cardiology, Montreal Heart Institute, Universite de Montreal, Montreal, Canada
    J Cardiovasc Electrophysiol 24:692-8. 2013
    ..We conducted a randomized preclinical trial to compare 2- versus 4-minute ablation lesions and assess the safety of active (forced) cryoballoon deflation...
  54. doi request reprint All-cause mortality and cardiovascular outcomes with prophylactic steroid therapy in Duchenne muscular dystrophy
    Gernot Schram
    Department of Cardiology, Montreal Heart Institute, Universite de Montreal, Montreal, Quebec, Canada
    J Am Coll Cardiol 61:948-54. 2013
    ..This study sought to determine the impact of steroid therapy on cardiomyopathy and mortality in patients with Duchenne muscular dystrophy (DMD)...
  55. doi request reprint Adenosine following pulmonary vein isolation to target dormant conduction elimination (ADVICE): methods and rationale
    Laurent Macle
    Montreal Heart Institute and Montreal Heart Institute Coordinating Centre, Universite de Montreal, Montreal, Quebec, Canada
    Can J Cardiol 28:184-90. 2012
    ..The Adenosine Following Pulmonary Vein Isolation to Target Dormant Conduction Elimination (ADVICE) study is a prospective multicentre randomized trial assessing the impact of adenosine-guided PVI in preventing AF recurrences...
  56. doi request reprint Differential effectiveness of pharmacological strategies to reveal dormant pulmonary vein conduction: a clinical-experimental correlation
    Tomas Datino
    Department of Medicine, Montreal Heart Institute and Universite de Montreal, Montreal, Quebec, Canada
    Heart Rhythm 8:1426-33. 2011
    ..Adenosine or isoproterenol are used clinically to reveal dormant PV conduction and guide additional ablation...
  57. doi request reprint Prediction of complications in pregnant women with cardiac diseases referred to a tertiary center
    Nicole Jastrow
    Department of Obstetrics and Gynecology, Sainte Justine Hospital, University of Montreal, Montreal QC, Canada
    Int J Cardiol 151:209-13. 2011
    ..We aimed to assess cardiac, obstetrical and neonatal complications in pregnant women with heart disease referred to our tertiary care center and validate a previously proposed risk index...
  58. pmc Cryoballoon ablation for atrial fibrillation
    Jason G Andrade
    Electrophysiology Service, Department of Cardiology, Montreal Heart Institute, Universite de Montreal, Montreal, Canada
    Indian Pacing Electrophysiol J 12:39-53. 2012
    ....
  59. doi request reprint Arterial flow measurements during reactive hyperemia using NIRS
    Francois Harel
    Department of Nuclear Medicine of the Montreal Heart Institute, Montreal, Quebec, Canada
    Physiol Meas 29:1033-40. 2008
    ..SGP and NIRS methods showed excellent reproducibility with the same intra-class correlation coefficients (0.98). In conclusion, the NIRS technique appears well suited for non-invasive evaluation of quantitative arterial forearm flow...
  60. ncbi request reprint Low-molecular-weight heparin in pregnant women with prosthetic heart valves
    Laurence M Descarries
    Department of Medicine, Montreal Heart Institute, Montreal, Quebec, Canada
    J Heart Valve Dis 15:679-85. 2006
    ..Low-molecular-weight heparin (LMWH) is considered a recommended anticoagulation option in pregnant women with prosthetic heart valves. However, few data are available regarding the efficacy and safety of LMWH in this setting...
  61. ncbi request reprint Near-infrared spectroscopy to monitor peripheral blood flow perfusion
    Francois Harel
    Department of Nuclear Medicine, Universite de Montreal, Montreal, Quebec, Canada H1T 1C8
    J Clin Monit Comput 22:37-43. 2008
    ..The technique uses near-infrared spectroscopy (NIRS) to determine the rate of change of forearm tissue saturation during reactive hyperemia...
  62. doi request reprint Diaphragmatic electromyography during cryoballoon ablation: a novel concept in the prevention of phrenic nerve palsy
    Frederic Franceschi
    Electrophysiology Service, Montreal Heart Institute, Universite de Montreal, Montreal, Canada
    Heart Rhythm 8:885-91. 2011
    ..Hemidiaphragmatic paralysis is the most frequent complication associated with cryoballoon ablation for atrial fibrillation. To date, no preventive strategy has proved effective...
  63. doi request reprint Maintenance of sinus rhythm and survival in patients with heart failure and atrial fibrillation
    Mario Talajic
    Research Center, Montreal Heart Institute, 5000 Belanger Street, Montreal, Quebec, Canada
    J Am Coll Cardiol 55:1796-802. 2010
    ..The goal of this study was to evaluate the relationship between the presence of sinus rhythm and outcomes in patients with a history of congestive heart failure (CHF) and atrial fibrillation (AF)...
  64. ncbi request reprint New approaches to atrial fibrillation management: a critical review of a rapidly evolving field
    Stanley Nattel
    Department of Medicine and Research Center, Montreal Heart Institute and University of Montreal, Montreal, Quebec, Canada
    Drugs 62:2377-97. 2002
    ..In conclusion, significant advances are being made in the management of patients with AF but much more work remains to be done...
  65. doi request reprint Transcatheter cryoablation part II: clinical utility
    Kristina Lemola
    Electrophysiology Service, Department of Cardiology, Montreal Heart Institute, Montreal, Canada
    Pacing Clin Electrophysiol 31:235-44. 2008
  66. doi request reprint Changing mortality in congenital heart disease
    Paul Khairy
    Adult Congenital Heart Center, Montreal Heart Institute, University of Montreal, Quebec, Canada
    J Am Coll Cardiol 56:1149-57. 2010
    ..This study sought to characterize temporal trends in all-cause mortality in patients with congenital heart disease (CHD)...
  67. ncbi request reprint Recent advances in adult congenital heart disease
    Laurianne Le Gloan
    Adult Congenital Heart Center, Montreal Heart Institute, Universite de Montreal, Montreal, Canada
    Circ J 75:2287-95. 2011
    ..This review highlights recent advances across the wide spectrum of key issues encountered by adults with CHD...
  68. doi request reprint Evaluation of adult congenital heart disease by cardiac magnetic resonance imaging
    Francois Marcotte
    Adult Congenital Heart Center, Montreal Heart Institute, Montreal, Quebec H1T 1C8, Canada
    Congenit Heart Dis 4:216-30. 2009
    ..Proficient scanning is further enabled by clearly outlined study objectives with prior documentation of interventional and surgical procedures, where applicable...
  69. ncbi request reprint Images in cardiovascular medicine. Left ventricular pseudoaneurysm: a late complication of low-energy DC ablation
    Fadi Mansour
    Department of Cardiology, Montreal Heart Institute, Montreal, Canada
    Circulation 113:e780-1. 2006
  70. doi request reprint Gated blood-pool SPECT versus cardiac magnetic resonance imaging for the assessment of left ventricular volumes and ejection fraction
    Francois Harel
    Department of Nuclear Medicine, Montreal Heart Institute and University of Montreal, 5000 Belanger Street, Montreal, QC H1T 1C8, Canada
    J Nucl Cardiol 17:427-34. 2010
    ..The goal is to assess the accuracy of a recently developed GBPS algorithm...
  71. ncbi request reprint Alternating narrow and wide complex tachycardia
    Paul Khairy
    Electrophysiology Service, Department of Medicine, Montreal Heart Institute, Montreal, Quebec, Canada
    Pacing Clin Electrophysiol 25:103-4. 2002
  72. doi request reprint Atrial fibrillation: a real-life observational study in the Québec population
    Jason R Guertin
    Pharmacoeconomic and Pharmacoepidemiology Research Unit, Research Centre, Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada
    Can J Cardiol 27:794-9. 2011
    ..Our objectives were to characterize the Québec AF patient population at the time of diagnosis of AF, quantify medical resource use prior to and after the initial diagnosis of AF, and determine overall survival...
  73. ncbi request reprint Angiotensin receptor blockade and exercise capacity in adults with systemic right ventricles: a multicenter, randomized, placebo-controlled clinical trial
    Annie Dore
    Department of Medicine, Montreal Heart Institute, Montreal, Canada
    Circulation 112:2411-6. 2005
    ..Pharmacological blockade of the renin-angiotensin system improves exercise tolerance in patients with left ventricular dysfunction, yet its impact on patients with systemic right ventricles (RVs) remains unknown...
  74. ncbi request reprint Nocturnal breathing in cyanotic congenital heart disease
    Sylvie Legault
    Adult Congenital Heart Center, Montreal Heart Institute and Universite de Montreal, Montreal, Quebec, Canada
    Int J Cardiol 128:197-200. 2008
    ..Sleep aggravated hypoxia has been observed in many such patients, but it remains to be determined whether sleep disordered breathing is contributory. We, therefore, sought to assess sleep-related breathing pattern in patients with CCHD...
  75. ncbi request reprint Tako-tsubo cardiomyopathy following transcatheter radiofrequency ablation of the atrioventricular node
    Wadi Mawad
    Electrophysiology Service, Montreal Heart Institute, 5000 Belanger Street E, Montreal, QC, Canada
    Europace 9:1075-6. 2007
    ..We speculate that the increase in sympathetic activity that accompanies AV node ablation contributed to the pathophysiological process, which involves increased catecholamines and/or apical adrenoreceptor density and responsiveness...
  76. ncbi request reprint SPECT versus planar gated blood pool imaging for left ventricular evaluation
    Francois Harel
    Department of Nuclear Medicine, Montreal Heart Institute and Universite de Montreal, Montreal, Quebec, Canada
    J Nucl Cardiol 14:544-9. 2007
    ..We developed a new segmentation algorithm based on the invariance of the Laplacian (IL) to compute volumes and ejection fractions and compared these results with planar analysis and gradients by use of a standard algorithm (QBS)...
  77. doi request reprint Elevated depression symptoms predict long-term cardiovascular mortality in patients with atrial fibrillation and heart failure
    Nancy Frasure-Smith
    Montreal Heart Institute Research Centre, Montreal, Quebec, Canada
    Circulation 120:134-40, 3p following 140. 2009
    ....
  78. doi request reprint Comparison of left ventricular contraction homogeneity index using SPECT gated blood pool imaging and planar phase analysis
    Francois Harel
    Department of Nuclear Medicine, Montreal Heart Institute and Universite de Montreal, Montreal, Quebec, Canada
    J Nucl Cardiol 15:80-5. 2008
    ..We describe a novel 3-dimensional (3D) gated blood pool single photon emission computed tomography (SPECT) approach, from which a contraction homogeneity index (CHI) is derived and compared with planar phase analyses...
  79. doi request reprint Right ventricular endocarditis in a pregnant woman with a restrictive ventricular septal defect
    Laurianne Le Gloan
    Adult Congenital Heart Disease Centre, Montreal Heart Institute Department of Obstetrics and Gynaecology, Sainte Justine Hospital, Universite de Montreal, 5000 Belanger StreetEast, Montreal, QC, Canada
    Congenit Heart Dis 6:638-40. 2011
    ..The remaining peripartum and postpartum course was relatively unremarkable. Percutaneous closure of the ventricular septal defect was successfully performed postpartum...
  80. doi request reprint Transcatheter cryoablation part I: preclinical experience
    Paul Khairy
    Electrophysiology Service, Department of Cardiology, Montreal Heart Institute, Montreal, Canada
    Pacing Clin Electrophysiol 31:112-20. 2008
  81. doi request reprint Implantable rhythm devices and electromagnetic interference: myth or reality?
    Katia Dyrda
    Electrophysiology Service, Department of Cardiology, Montreal Heart Institute, University of Montreal, Montreal, Canada
    Expert Rev Cardiovasc Ther 6:823-32. 2008
    ..This review provides a contemporary overview of the current state of knowledge regarding risks attributable to EMI; highlights current limitations of implantable rhythm devices; and attempts to distinguish myths from realities...
  82. ncbi request reprint Transcatheter mapping and ablation of arrhythmias in the coronary sinus
    Grigorios Katsouras
    Montreal Heart Institute, Electrophysiology and Adult Congenital Heart Disease, 5000 Belanger St E, Montreal, QC H1T 1C8, Canada
    Expert Rev Cardiovasc Ther 4:711-20. 2006
    ....
  83. doi request reprint ICD monitoring zones: intricacies, pitfalls, and programming tips
    Fadi Mansour
    Electrophysiology Service, Department of Medicine, Montreal Heart Institute, Montreal, Canada
    J Cardiovasc Electrophysiol 19:568-74. 2008
    ..Herein, we unravel the intricacies regarding monitoring zone functions and algorithms, highlight potential pitfalls, and offer practical programming tips relevant to each device manufacturer...
  84. ncbi request reprint Absence of association between infectious agents and endothelial function in healthy young men
    Paul Khairy
    Department of Medicine, Montreal Heart Institute, University of Montreal, Quebec, Canada
    Circulation 107:1966-71. 2003
    ..This study assessed whether infection with Chlamydia pneumoniae (CP), cytomegalovirus (CMV), Epstein-Barr virus (EBV), or Helicobacter pylori (HP) is associated with decreased endothelial function...
  85. ncbi request reprint Mönckeberg's sling
    Paul Khairy
    Electrophysiology Service, Montreal Heart Institute, Quebec, Canada
    Can J Cardiol 19:717-8. 2003
  86. ncbi request reprint Morphology of bicuspid aortic valve in children and adolescents
    Susan M Fernandes
    Department of Cardiology, Children s Hospital, 300 Longwood Avenue, Boston, MA 02115, USA
    J Am Coll Cardiol 44:1648-51. 2004
    ..The aim of this study was to determine the relationship between aortic valve morphology and valve dysfunction...
  87. ncbi request reprint Ablation of atrioventricular nodal reentrant tachycardia in tricuspid atresia
    Paul Khairy
    Electrophysiology Service, Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Cardiovasc Electrophysiol 15:719-22. 2004
    ..Successful radiofrequency ablation was achieved by placement of lesions in an area adjacent and inferior to the His-bundle electrogram on the left side of the septum...
  88. pmc New insights into the mechanisms and management of atrial fibrillation
    Paul Khairy
    Department of Medicine, Universite de Montreal, Montreal, Que
    CMAJ 167:1012-20. 2002
    ..Finally, we discuss recent insights into the basic mechanisms underlying AF that have potentially significant clinical implications...
  89. ncbi request reprint Value of programmed ventricular stimulation after tetralogy of fallot repair: a multicenter study
    Paul Khairy
    Boston Adult Congenital Heart and Electrophysiology Services, Department of Cardiology, Children s Hospital Boston, 300 Longwood Ave, Boston, Mass 02115, USA
    Circulation 109:1994-2000. 2004
    ....
  90. ncbi request reprint Inability to cannulate the coronary sinus in patients with supraventricular arrhythmias: congenital and acquired coronary sinus atresia
    Paul Khairy
    Electrophysiology Service, Department of Cardiology, Children s Hospital Boston, Harvard Medical School, USA
    J Interv Card Electrophysiol 12:123-7. 2005
    ....
  91. ncbi request reprint Long-term outcomes after the atrial switch for surgical correction of transposition: a meta-analysis comparing the Mustard and Senning procedures
    Paul Khairy
    Boston Adult Congenital Heart Service, Brigham and Women s Hospital, USA
    Cardiol Young 14:284-92. 2004
    ..We conclude that outcomes are not uniform among patients submitted to the Mustard and Senning procedures. Knowledge of such differences may facilitate stratification of risk and follow-up...
  92. ncbi request reprint Radiofrequency catheter ablation of ventricular tachycardia in children and young adults with congenital heart disease
    James G Morwood
    Department of Cardiology, Boston Children s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Heart Rhythm 1:301-8. 2004
    ..The aim of this study was to expand data on outcomes for radiofrequency catheter ablation (RFCA) of ventricular tachycardia (VT) in young patients and to identify obstacles to success...
  93. ncbi request reprint Pregnancy outcomes in women with congenital heart disease
    Paul Khairy
    Boston Adult Congenital Heart Service, Brigham and Women s Hospital, Boston, MA, USA
    Circulation 113:517-24. 2006
    ..Pregnant women with congenital heart disease are at increased risk for cardiac and neonatal complications, yet risk factors for adverse outcomes are not fully defined...
  94. ncbi request reprint Inaccuracy of Wolff-Parkinson-white accessory pathway localization algorithms in children and patients with congenital heart defects
    Yaniv Bar-Cohen
    Electrophysiology Division, Department of Cardiology, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    J Cardiovasc Electrophysiol 17:712-6. 2006
    ..We hypothesize that these algorithms have low diagnostic accuracy in children and even lower in those with CHD...
  95. ncbi request reprint Thirty years of experience with epicardial pacing in children
    Nicolas Noiseux
    Department of Cardiovascular Surgery, Children s Hospital Boston, Harvard Medical School, USA
    Cardiol Young 14:512-9. 2004
    ..A substantial proportion, nonetheless, requires reintervention within five years, warranting meticulous follow-up...
  96. ncbi request reprint Bicuspid aortic valve morphology and interventions in the young
    Susan M Fernandes
    Department of Cardiology, Children s Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 49:2211-4. 2007
    ..The aim of this study was to determine whether the morphologic subtype of bicuspid aortic valve (BAV) is associated with valve intervention in the young...
  97. ncbi request reprint Long-term survival, modes of death, and predictors of mortality in patients with Fontan surgery
    Paul Khairy
    Boston Adult Congenital Heart Service, Brigham and Women s Hospital, Harvard Medical School, Boston, Mass 02115, USA
    Circulation 117:85-92. 2008
    ..To better define determinants of mortality in patients with univentricular physiology, a database registry was created of patients born in 1985 or earlier with Fontan surgery who were followed up at Children's Hospital Boston...
  98. doi request reprint Defibrillators and cardiac resynchronization therapy in congenital heart disease: evolving indications
    Paul Khairy
    Expert Rev Med Devices 5:267-71. 2008
  99. doi request reprint Adult congenital heart disease: toward prospective risk assessment of a multisystemic condition
    Paul Khairy
    Circulation 117:2311-2. 2008
  100. ncbi request reprint Transcatheter closure versus medical therapy of patent foramen ovale and presumed paradoxical thromboemboli: a systematic review
    Paul Khairy
    Boston Adult Congenital Heart Service, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    Ann Intern Med 139:753-60. 2003
    ..The optimal strategy to prevent recurrent presumed paradoxical emboli in patients with patent foramen ovale is unknown...