Karen Tu

Summary

Affiliation: Institute for Clinical Evaluative Sciences
Country: Canada

Publications

  1. ncbi request reprint Antihypertensive drug prescribing and persistence among new elderly users: implications for persistence improvement interventions
    Karen Tu
    Institute for Clinical Evaluative Sciences ICES, Toronto, Ontario, Canada Department of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada University Health Network Toronto Western Hospital Family Health Team, Toronto, Ontario, Canada Electronic address
    Can J Cardiol 30:647-52. 2014
  2. doi request reprint Validity of administrative data for identifying patients who have had a stroke or transient ischemic attack using EMRALD as a reference standard
    Karen Tu
    Institute for Clinical Evaluative Sciences ICES, Toronto, Ontario, Canada Department of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada Toronto Western Hospital Family Health Team, Toronto, Ontario, Canada Electronic address
    Can J Cardiol 29:1388-94. 2013
  3. pmc Feedback GAP: study protocol for a cluster-randomized trial of goal setting and action plans to increase the effectiveness of audit and feedback interventions in primary care
    Noah M Ivers
    Women s College Hospital Family Health Team, 76 Grenville Street, Toronto ON, M5 S 1B2, Canada
    Implement Sci 5:98. 2010
  4. doi request reprint Diabetics can be identified in an electronic medical record using laboratory tests and prescriptions
    Karen Tu
    Institute for Clinical Evaluative Sciences, Toronto, Ontario M4N 3M5, Canada
    J Clin Epidemiol 64:431-5. 2011
  5. pmc De-identification of primary care electronic medical records free-text data in Ontario, Canada
    Karen Tu
    Institute for Clinical Evaluative Sciences G106, Toronto, Ontario, M4N 3M5, Canada
    BMC Med Inform Decis Mak 10:35. 2010
  6. ncbi request reprint Is ramipril really better than other angiotensin-converting enzyme inhibitors after acute myocardial infarction?
    Karen Tu
    Institute for Clinical Evaluative Sciences, University of Toronto, Toronto, Ontario, Canada
    Am J Cardiol 98:6-9. 2006
  7. ncbi request reprint Comparison of angiotensin-converting enzyme inhibitors in the treatment of congestive heart failure
    Karen Tu
    Institute for Clinical Evaluative Sciences, G106 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Am J Cardiol 95:283-6. 2005
  8. pmc Comparison of primary care physician payment models in the management of hypertension
    Karen Tu
    ICES, Toronto, ON M4N 3M5
    Can Fam Physician 55:719-27. 2009
  9. pmc Prevalence and incidence of hypertension from 1995 to 2005: a population-based study
    Karen Tu
    Institute for Clinical Evaluative Sciences, University of Toronto, Toronto, Ont
    CMAJ 178:1429-35. 2008
  10. pmc Validation of physician billing and hospitalization data to identify patients with ischemic heart disease using data from the Electronic Medical Record Administrative data Linked Database (EMRALD)
    Karen Tu
    Department of Family and Community Medicine, University of Toronto, Ontario
    Can J Cardiol 26:e225-8. 2010

Detail Information

Publications49

  1. ncbi request reprint Antihypertensive drug prescribing and persistence among new elderly users: implications for persistence improvement interventions
    Karen Tu
    Institute for Clinical Evaluative Sciences ICES, Toronto, Ontario, Canada Department of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada University Health Network Toronto Western Hospital Family Health Team, Toronto, Ontario, Canada Electronic address
    Can J Cardiol 30:647-52. 2014
    ..The objective of this study was to examine persistence rates and factors influencing persistence for new elderly users of antihypertensive drugs...
  2. doi request reprint Validity of administrative data for identifying patients who have had a stroke or transient ischemic attack using EMRALD as a reference standard
    Karen Tu
    Institute for Clinical Evaluative Sciences ICES, Toronto, Ontario, Canada Department of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada Toronto Western Hospital Family Health Team, Toronto, Ontario, Canada Electronic address
    Can J Cardiol 29:1388-94. 2013
    ..We examined whether the accuracy of administrative data for identifying prevalent stroke/TIA could be improved by using data from both inpatient and outpatient visits...
  3. pmc Feedback GAP: study protocol for a cluster-randomized trial of goal setting and action plans to increase the effectiveness of audit and feedback interventions in primary care
    Noah M Ivers
    Women s College Hospital Family Health Team, 76 Grenville Street, Toronto ON, M5 S 1B2, Canada
    Implement Sci 5:98. 2010
    ..abstract:..
  4. doi request reprint Diabetics can be identified in an electronic medical record using laboratory tests and prescriptions
    Karen Tu
    Institute for Clinical Evaluative Sciences, Toronto, Ontario M4N 3M5, Canada
    J Clin Epidemiol 64:431-5. 2011
    ..We set out to determine if diabetics could be accurately identified using structured data contained within an EMR...
  5. pmc De-identification of primary care electronic medical records free-text data in Ontario, Canada
    Karen Tu
    Institute for Clinical Evaluative Sciences G106, Toronto, Ontario, M4N 3M5, Canada
    BMC Med Inform Decis Mak 10:35. 2010
    ..While de-identification tools have been developed for free-text, none have been developed or tested for the full range of primary care EMR data..
  6. ncbi request reprint Is ramipril really better than other angiotensin-converting enzyme inhibitors after acute myocardial infarction?
    Karen Tu
    Institute for Clinical Evaluative Sciences, University of Toronto, Toronto, Ontario, Canada
    Am J Cardiol 98:6-9. 2006
    ..84 to 1.25), or other ACE inhibitors (adjusted hazard ratio 1.08, 95% confidence interval 0.88, 1.32). In conclusion, the findings of this study support a class effect among ACE inhibitors in treatment after AMI...
  7. ncbi request reprint Comparison of angiotensin-converting enzyme inhibitors in the treatment of congestive heart failure
    Karen Tu
    Institute for Clinical Evaluative Sciences, G106 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Am J Cardiol 95:283-6. 2005
    ..In terms of effectiveness for the treatment of patients with CHF, the findings of this study suggest a class effect among ACE inhibitors...
  8. pmc Comparison of primary care physician payment models in the management of hypertension
    Karen Tu
    ICES, Toronto, ON M4N 3M5
    Can Fam Physician 55:719-27. 2009
    ..To determine primary care physician screening, treatment, and control rates for hypertension and to examine whether type of physician payment model affected these rates...
  9. pmc Prevalence and incidence of hypertension from 1995 to 2005: a population-based study
    Karen Tu
    Institute for Clinical Evaluative Sciences, University of Toronto, Toronto, Ont
    CMAJ 178:1429-35. 2008
    ..Thus, accurate estimates of the prevalence of hypertension in a population have important implications for public policy. We sought to assess whether the estimated increase in the prevalence of hypertension has been underestimated...
  10. pmc Validation of physician billing and hospitalization data to identify patients with ischemic heart disease using data from the Electronic Medical Record Administrative data Linked Database (EMRALD)
    Karen Tu
    Department of Family and Community Medicine, University of Toronto, Ontario
    Can J Cardiol 26:e225-8. 2010
    ..Reporting of ischemic heart disease (IHD) prevalence in Canada has been based on self-report or patients presenting to hospital. However, IHD often presents and can be managed in the outpatient setting...
  11. ncbi request reprint Myocardial infarction and the validation of physician billing and hospitalization data using electronic medical records
    K Tu
    Institute for Clinical Evaluative Sciences ICES, Toronto, Canada
    Chronic Dis Can 30:141-6. 2010
    ..We set out to determine if adding physician billing data to hospital discharge data would result in an accurate capture of patients who have had a myocardial infarction...
  12. ncbi request reprint An overview of the types of physicians treating acute cardiac conditions in Canada
    Karen Tu
    Institute for Clinical Evaluative Sciences, Toronto, Ontario
    Can J Cardiol 20:282-91. 2004
    ..As the issue of physician supply and distribution increases in intensity in Canada, the scope of practice of different types of physicians becomes increasingly important...
  13. ncbi request reprint Hypertension guidelines in elderly patients: is anybody listening?
    Karen Tu
    Institute for Clinical Evaluative Services, G106 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Am J Med 113:52-8. 2002
    ....
  14. pmc Trends in risk factors for cardiovascular disease in Canada: temporal, socio-demographic and geographic factors
    Douglas S Lee
    Institute for Clinical Evaluative Sciences, Toronto, Ont
    CMAJ 181:E55-66. 2009
    ..Temporal trends in risk factors for cardiovascular disease and the impact of socio-economic status on these risk factors remain unclear...
  15. pmc Mortality among patients with hypertension from 1995 to 2005: a population-based study
    Karen Tu
    Institute for Clinical Evaluative Sciences, University of Toronto, Toronto, Ont
    CMAJ 178:1436-40. 2008
    ..We have reported that the prevalence of diagnosed hypertension increased by 60% from 1995 to 2005 in Ontario. In the present study, we asked whether this increase is explained by a decrease in the mortality rate...
  16. pmc An administrative data validation study of the accuracy of algorithms for identifying rheumatoid arthritis: the influence of the reference standard on algorithm performance
    Jessica Widdifield
    University of Toronto, Toronto, 200 Elizabeth St 13EN 224, Toronto, ON M5G 2C4, Canada
    BMC Musculoskelet Disord 15:216. 2014
    ..Here we reassessed the accuracy of the algorithms using primary care records as the reference standard...
  17. doi request reprint Antihypertensive drug persistence and compliance among newly treated elderly hypertensives in ontario
    Oded Friedman
    Prosserman Centre for Health Research Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
    Am J Med 123:173-81. 2010
    ..Poor medication-taking behaviors are important considerations in the management of hypertension...
  18. ncbi request reprint Thiazide diuretics for hypertension: prescribing practices and predictors of use in 194,761 elderly patients with hypertension
    Karen Tu
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Am J Geriatr Pharmacother 4:161-7. 2006
    ..Although several small studies have reported underuse of thiazide diuretics for elderly hypertensive patients, those factors which influence initial choice of first-line antihypertensive treatment are unknown...
  19. ncbi request reprint Hypertension management in the elderly has improved: Ontario prescribing trends, 1994 to 2002
    Karen Tu
    Institute for Clinical Evaluative Sciences, Toronto, Canada
    Hypertension 45:1113-8. 2005
    ..0001). Our data provide evidence that the physician management of hypertension in elderly Canadians became more aggressive between 1994 and 2002...
  20. ncbi request reprint The epidemiology of rheumatoid arthritis in Ontario, Canada
    Jessica Widdifield
    University of Toronto and Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Arthritis Rheumatol 66:786-93. 2014
    ..We undertook this study to describe the epidemiology of rheumatoid arthritis (RA) over the past 15 years...
  21. doi request reprint The risk of hip fracture after initiating antihypertensive drugs in the elderly
    Debra A Butt
    Ellesmere Health Care Centre and The Scarborough Hospital, Scarborough, Ontario, Canada
    Arch Intern Med 172:1739-44. 2012
    ....
  22. pmc Feedback GAP: pragmatic, cluster-randomized trial of goal setting and action plans to increase the effectiveness of audit and feedback interventions in primary care
    Noah M Ivers
    Department of Family and Community Medicine, Women s College Hospital, 76 Grenville Street, Toronto, ON M5S 1B2, Canada
    Implement Sci 8:142. 2013
    ..This trial tested the effects of a theory-informed worksheet to facilitate goal setting and action planning, appended to feedback reports on chronic disease management, compared to feedback reports provided without these worksheets...
  23. ncbi request reprint Influence of socioeconomic status on drug selection for the elderly in Canada
    Muhammad M Mamdani
    Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G215, Toronto, Ontario M4N 3M5, Canada
    Ann Pharmacother 36:804-8. 2002
    ....
  24. pmc The striking effect of the Heart Outcomes Prevention Evaluation (HOPE) on ramipril prescribing in Ontario
    Karen Tu
    Institute for Clinical Evaluative Sciences, University Health Network Toronto Western Hospital Family Medicine Center and Department of Family and Community Health Family Health Research Unit, University of Toronto, Toronto, ON
    CMAJ 168:553-7. 2003
    ..We studied whether HOPE affected the prescribing of ACE inhibitors generally, and ramipril specifically, in Ontario, where the trial was coordinated...
  25. doi request reprint Assessing the validity of using administrative data to identify patients with epilepsy
    Karen Tu
    Institute for Clinical Evaluative Sciences ICES, Toronto, Ontario, Canada Department of Family and Community Medicine, University of Toronto, Toronto, Ontario, Canada Toronto Western Hospital Family Health Team, University Health Network, Toronto, Ontario, Canada
    Epilepsia 55:335-43. 2014
    ..The purpose of this study was to determine the validity of using administrative data to identify patients with epilepsy in the general population...
  26. ncbi request reprint Trends in cardiovascular drug utilization and drug expenditures in Canada between 1996 and 2001
    Cynthia A Jackevicius
    Pharmacy Department, University Health Network Toronto General Hospital, Toronto, Ontario, Canada
    Can J Cardiol 19:1359-66. 2003
    ..There is increasing interest in studying trends in drug utilization because drug costs are the fastest growing sector of the health care system...
  27. pmc National trends in rates of death and hospital admissions related to acute myocardial infarction, heart failure and stroke, 1994-2004
    Jack V Tu
    Institute for Clinical Evaluative Sciences, Toronto, Ont
    CMAJ 180:E118-25. 2009
    ..We examined recent national trends in mortality and rates of hospital admission for these 3 conditions...
  28. ncbi request reprint Association between ACE inhibitors and acute pancreatitis in the elderly
    Roger M S Cheng
    Princess Margaret Hospital, Toronto, Ontario, Canada
    Ann Pharmacother 37:994-8. 2003
    ..At present, no epidemiologic studies examining the potential association between ACE inhibitors and acute pancreatitis have been identified...
  29. doi request reprint Implementing a standardized community-based cardiovascular risk assessment program in 20 Ontario communities
    Megan Carter
    Elisabeth Bruyere Research Institute, Ottawa, Ontario, Canada
    Health Promot Int 24:325-33. 2009
    ..Monitoring delivery of a multi-community cardiovascular risk assessment program yielded key factors in program success to inform development of a sustainable and transferable model...
  30. ncbi request reprint The impact of the Women's Health Initiative study on incident clonidine use in Ontario, Canada
    Peter C Austin
    Institute of Clinical Evaluative Sciences, Department of Public Health Sciences, University of Toronto
    Can J Clin Pharmacol 11:e191-4. 2004
    ..There is some evidence that the antihypertensive agent clonidine can reduce the frequency of hot flashes associated with menopause...
  31. pmc "My approach to this job is...one person at a time": Perceived discordance between population-level quality targets and patient-centred care
    Noah Ivers
    Women s College Hospital, Department of Family and Community Medicine, 77 Grenville St, 4th Floor, Toronto, ON M5S 1B3
    Can Fam Physician 60:258-66. 2014
    ..To understand the usefulness of audit and feedback among family physicians and examine the barriers to using it to improve quality of care...
  32. doi request reprint Accuracy of Canadian health administrative databases in identifying patients with rheumatoid arthritis: a validation study using the medical records of rheumatologists
    Jessica Widdifield
    University of Toronto, Toronto, Ontario, Canada
    Arthritis Care Res (Hoboken) 65:1582-91. 2013
    ..Few studies have rigorously evaluated the accuracy of administrative databases for identifying rheumatoid arthritis (RA) patients. Our aim was to validate administrative data algorithms to identify RA patients in Ontario, Canada...
  33. ncbi request reprint End-user support for a primary care electronic medical record: a qualitative case study of a vendor's perspective
    Aviv Shachak
    Faculty of Information, University of Toronto, Canada, ON M5T 3M6, Canada
    Inform Prim Care 20:185-95. 2012
    ..Yet, little is known about the vendors' perspectives on the support they provide, how support personnel perceive their roles, the challenges they face and the ways they deal with them...
  34. ncbi request reprint Inhaled or systemic corticosteroids and the risk of hospitalization for hip fracture among elderly women
    Elaine Lau
    Faculty of Pharmacy EL, MM, University of Toronto, Canada
    Am J Med 114:142-5. 2003
  35. pmc Waiting to see the specialist: patient and provider characteristics of wait times from primary to specialty care
    Liisa Jaakkimainen
    Institute for Clinical Evaluative Sciences, 2075 Bayview Ave, G Wing, Toronto, Ontario M4N 3M5, Canada
    BMC Fam Pract 15:16. 2014
    ..Our objectives were to calculate the wait times from when a referral is made by a family physician (FP) to when a patient sees a specialist physician and examine patient and provider factors related to these wait times...
  36. pmc Allocation techniques for balance at baseline in cluster randomized trials: a methodological review
    Noah M Ivers
    Family Practice Health Centre, Women s College Hospital, 76 Grenville Street, Toronto, ON, M5S1B2, Canada
    Trials 13:120. 2012
    ....
  37. ncbi request reprint Medical text analytics tools for search and classification
    Jimmy Huang
    Institute for Clinical Evaluative Sciences, York University, Toronto, ON, Canada
    Stud Health Technol Inform 143:519-24. 2009
    ..4) A summary is generated for each patient selected. Large medical data sets provided by the Institute for Clinical Evaluative Sciences were used during the project...
  38. ncbi request reprint Can we alter physician behavior by educational methods? Lessons learned from studies of the management and follow-up of hypertension
    Karen Tu
    Department of Family and Community Medicine, Family Healthcare Research Unit, Faculty of Medicine, University of Toronto, Institute for Clinical Evaluative Sciences, Toronto Western Hospital University Health Network Family Health Centre, Toronto, Ontario
    J Contin Educ Health Prof 22:11-22. 2002
    ..Thus, we set out to review the literature on the effectiveness of physician educational interventions in the management and follow-up of hypertension...
  39. pmc Trends in antihypertensive drug prescriptions and physician visits in Canada between 1996 and 2006
    Brenda R Hemmelgarn
    Department of Community of Health Sciences, University of Calgary, Calgary, Alberta
    Can J Cardiol 24:507-12. 2008
    ..In 1999, the Canadian Hypertension Education Program (CHEP) was launched to develop and implement evidence-based hypertension guidelines...
  40. ncbi request reprint Cardiovascular Health Awareness Program (CHAP): a community cluster-randomised trial among elderly Canadians
    Janusz Kaczorowski
    Department of Family Practice, University of British Columbia, Canada
    Prev Med 46:537-44. 2008
    ..The present study is a community cluster-randomised trial testing the effectiveness of CHAP (Cardiovascular Health Awareness Program) on the cardiovascular health of older adults...
  41. ncbi request reprint Antihypertensive therapy and incidence of type 2 diabetes in an elderly cohort
    Raj Padwal
    Division of General Internal Medicine, University of Alberta, Edmonton, Canada
    Diabetes Care 27:2458-63. 2004
    ..The aim of this study was to determine whether the incidence of type 2 diabetes differed among elderly users of four major antihypertensive drug classes...
  42. ncbi request reprint The impact of the Canadian Hypertension Education Program on antihypertensive prescribing trends
    Norman R C Campbell
    Department of Medicine, University of Calgary, Calgary, Canada
    Hypertension 47:22-8. 2006
    ....
  43. ncbi request reprint Antihypertensive medication prescribing in 27,822 elderly Canadians with diabetes over the past decade
    Finlay A McAlister
    Department of Medicine, University of Alberta, Edmonton, Alberta T6G 2R7, Canada
    Diabetes Care 29:836-41. 2006
    ..The purpose of this study was to examine whether prescribing practices for elderly individuals with diabetes and hypertension changed over the past decade...
  44. pmc Estimate of the benefits of a population-based reduction in dietary sodium additives on hypertension and its related health care costs in Canada
    Michel R Joffres
    Simon Fraser University, Burnaby, British Columbia, Canada
    Can J Cardiol 23:437-43. 2007
    ..Reductions in dietary sodium additives significantly lower systolic and diastolic blood pressure, and population reductions in dietary sodium are recommended by major scientific and public health organizations...
  45. pmc Polytherapy with two or more antihypertensive drugs to lower blood pressure in elderly Ontarians. Room for improvement
    Norman R C Campbell
    Department of Medicine, Libin Cardiovascular Institute, University of Calgary, Calgary, AB, Canada
    Can J Cardiol 23:783-7. 2007
    ..Although guidelines now recommend polytherapy to achieve blood pressure targets, little is know about which antihypertensive drugs are combined in clinical practice...
  46. ncbi request reprint Prescriptions for estrogen replacement therapy in Ontario before and after publication of the Women's Health Initiative Study
    Peter C Austin
    JAMA 289:3241-2. 2003
  47. ncbi request reprint A rural CT scanner: evaluating the effect on local health care
    Barbara J Merkens
    Barbara Merkens and Associates, Don Mills, ON
    Can Assoc Radiol J 57:224-31. 2006
    ..This evaluation study had 3 parts: a survey of physicians, a survey of patients, and an analysis of population CT scanning rates...
  48. ncbi request reprint Changes in prescribing patterns following publication of the ALLHAT trial
    Peter C Austin
    JAMA 291:44-5. 2004