Research Topics
| Karen TuSummaryAffiliation: Institute for Clinical Evaluative Sciences Country: Canada Publications
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Detail Information
Publications
Feedback GAP: study protocol for a cluster-randomized trial of goal setting and action plans to increase the effectiveness of audit and feedback interventions in primary careNoah M Ivers
Women s College Hospital Family Health Team, 76 Grenville Street, Toronto ON, M5 S 1B2, Canada
Implement Sci 5:98. 2010..abstract:..
Comparison of angiotensin-converting enzyme inhibitors in the treatment of congestive heart failureKaren Tu
Institute for Clinical Evaluative Sciences, G106 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
Am J Cardiol 95:283-6. 2005..In terms of effectiveness for the treatment of patients with CHF, the findings of this study suggest a class effect among ACE inhibitors...
Diabetics can be identified in an electronic medical record using laboratory tests and prescriptionsKaren Tu
Institute for Clinical Evaluative Sciences, Toronto, Ontario M4N 3M5, Canada
J Clin Epidemiol 64:431-5. 2011..We set out to determine if diabetics could be accurately identified using structured data contained within an EMR...
An overview of the types of physicians treating acute cardiac conditions in CanadaKaren Tu
Institute for Clinical Evaluative Sciences, Toronto, Ontario
Can J Cardiol 20:282-91. 2004..As the issue of physician supply and distribution increases in intensity in Canada, the scope of practice of different types of physicians becomes increasingly important...
Validation of physician billing and hospitalization data to identify patients with ischemic heart disease using data from the Electronic Medical Record Administrative data Linked Database (EMRALD)Karen Tu
Department of Family and Community Medicine, University of Toronto, Ontario
Can J Cardiol 26:e225-8. 2010..Reporting of ischemic heart disease (IHD) prevalence in Canada has been based on self-report or patients presenting to hospital. However, IHD often presents and can be managed in the outpatient setting...
Is ramipril really better than other angiotensin-converting enzyme inhibitors after acute myocardial infarction?Karen Tu
Institute for Clinical Evaluative Sciences, University of Toronto, Toronto, Ontario, Canada
Am J Cardiol 98:6-9. 2006..84 to 1.25), or other ACE inhibitors (adjusted hazard ratio 1.08, 95% confidence interval 0.88, 1.32). In conclusion, the findings of this study support a class effect among ACE inhibitors in treatment after AMI...
De-identification of primary care electronic medical records free-text data in Ontario, CanadaKaren Tu
Institute for Clinical Evaluative Sciences G106, Toronto, Ontario, M4N 3M5, Canada
BMC Med Inform Decis Mak 10:35. 2010..While de-identification tools have been developed for free-text, none have been developed or tested for the full range of primary care EMR data..
Myocardial infarction and the validation of physician billing and hospitalization data using electronic medical recordsK Tu
Institute for Clinical Evaluative Sciences ICES, Toronto, Canada
Chronic Dis Can 30:141-6. 2010..We set out to determine if adding physician billing data to hospital discharge data would result in an accurate capture of patients who have had a myocardial infarction...
Comparison of primary care physician payment models in the management of hypertensionKaren Tu
ICES, Toronto, ON M4N 3M5
Can Fam Physician 55:719-27. 2009..To determine primary care physician screening, treatment, and control rates for hypertension and to examine whether type of physician payment model affected these rates...
Prevalence and incidence of hypertension from 1995 to 2005: a population-based studyKaren Tu
Institute for Clinical Evaluative Sciences, University of Toronto, Toronto, Ont
CMAJ 178:1429-35. 2008..Thus, accurate estimates of the prevalence of hypertension in a population have important implications for public policy. We sought to assess whether the estimated increase in the prevalence of hypertension has been underestimated...
Hypertension guidelines in elderly patients: is anybody listening?Karen Tu
Institute for Clinical Evaluative Services, G106 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
Am J Med 113:52-8. 2002....
Trends in risk factors for cardiovascular disease in Canada: temporal, socio-demographic and geographic factorsDouglas S Lee
Institute for Clinical Evaluative Sciences, Toronto, Ont
CMAJ 181:E55-66. 2009..Temporal trends in risk factors for cardiovascular disease and the impact of socio-economic status on these risk factors remain unclear...
Mortality among patients with hypertension from 1995 to 2005: a population-based studyKaren Tu
Institute for Clinical Evaluative Sciences, University of Toronto, Toronto, Ont
CMAJ 178:1436-40. 2008..We have reported that the prevalence of diagnosed hypertension increased by 60% from 1995 to 2005 in Ontario. In the present study, we asked whether this increase is explained by a decrease in the mortality rate...
Antihypertensive drug persistence and compliance among newly treated elderly hypertensives in ontarioOded Friedman
Prosserman Centre for Health Research Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada
Am J Med 123:173-81. 2010..Poor medication-taking behaviors are important considerations in the management of hypertension...
Thiazide diuretics for hypertension: prescribing practices and predictors of use in 194,761 elderly patients with hypertensionKaren Tu
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Am J Geriatr Pharmacother 4:161-7. 2006..Socioeconomic status did not influence use of thiazides, but age, sex, and comorbidities did...
Hypertension management in the elderly has improved: Ontario prescribing trends, 1994 to 2002Karen Tu
Institute for Clinical Evaluative Sciences, Toronto, Canada
Hypertension 45:1113-8. 2005..0001). Our data provide evidence that the physician management of hypertension in elderly Canadians became more aggressive between 1994 and 2002...
The striking effect of the Heart Outcomes Prevention Evaluation (HOPE) on ramipril prescribing in OntarioKaren Tu
Institute for Clinical Evaluative Sciences, University Health Network Toronto Western Hospital Family Medicine Center and Department of Family and Community Health Family Health Research Unit, University of Toronto, Toronto, ON
CMAJ 168:553-7. 2003..We studied whether HOPE affected the prescribing of ACE inhibitors generally, and ramipril specifically, in Ontario, where the trial was coordinated...
Influence of socioeconomic status on drug selection for the elderly in CanadaMuhammad M Mamdani
Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G215, Toronto, Ontario M4N 3M5, Canada
Ann Pharmacother 36:804-8. 2002....
Trends in cardiovascular drug utilization and drug expenditures in Canada between 1996 and 2001Cynthia A Jackevicius
Pharmacy Department, University Health Network Toronto General Hospital, Toronto, Ontario, Canada
Can J Cardiol 19:1359-66. 2003..There is increasing interest in studying trends in drug utilization because drug costs are the fastest growing sector of the health care system...
Association between ACE inhibitors and acute pancreatitis in the elderlyRoger M S Cheng
Princess Margaret Hospital, Toronto, Ontario, Canada
Ann Pharmacother 37:994-8. 2003..11; 95% CI 0.79 to 1.56) were at significantly higher risk for pancreatic surgery. CONCLUSIONS: The use of ACE inhibitors does not appear to be associated with significant risk of acute pancreatitis among the elderly...
National trends in rates of death and hospital admissions related to acute myocardial infarction, heart failure and stroke, 1994-2004Jack V Tu
Institute for Clinical Evaluative Sciences, Toronto, Ont
CMAJ 180:E118-25. 2009..We examined recent national trends in mortality and rates of hospital admission for these 3 conditions...
Implementing a standardized community-based cardiovascular risk assessment program in 20 Ontario communitiesMegan Carter
Elisabeth Bruyere Research Institute, Ottawa, Ontario, Canada
Health Promot Int 24:325-33. 2009..Monitoring delivery of a multi-community cardiovascular risk assessment program yielded key factors in program success to inform development of a sustainable and transferable model...
The impact of the Women's Health Initiative study on incident clonidine use in Ontario, CanadaPeter C Austin
Institute of Clinical Evaluative Sciences, Department of Public Health Sciences, University of Toronto
Can J Clin Pharmacol 11:e191-4. 2004..There is some evidence that the antihypertensive agent clonidine can reduce the frequency of hot flashes associated with menopause...
Inhaled or systemic corticosteroids and the risk of hospitalization for hip fracture among elderly womenElaine Lau
Faculty of Pharmacy (EL, MM, University of Toronto, Canada
Am J Med 114:142-5. 2003
The risk of hip fracture after initiating antihypertensive drugs in the elderlyDebra A Butt
Ellesmere Health Care Centre and The Scarborough Hospital, Scarborough, Ontario, Canada
Arch Intern Med 172:1739-44. 2012....
Medical text analytics tools for search and classificationJimmy Huang
Institute for Clinical Evaluative Sciences, York University, Toronto, ON, Canada
Stud Health Technol Inform 143:519-24. 2009..4) A summary is generated for each patient selected. Large medical data sets provided by the Institute for Clinical Evaluative Sciences were used during the project...
Can we alter physician behavior by educational methods? Lessons learned from studies of the management and follow-up of hypertensionKaren Tu
Department of Family and Community Medicine, Family Healthcare Research Unit, Faculty of Medicine, University of Toronto, Institute for Clinical Evaluative Sciences, Toronto Western Hospital University Health Network Family Health Centre, Toronto, Ontario
J Contin Educ Health Prof 22:11-22. 2002..Thus, we set out to review the literature on the effectiveness of physician educational interventions in the management and follow-up of hypertension...
Trends in antihypertensive drug prescriptions and physician visits in Canada between 1996 and 2006Brenda R Hemmelgarn
Department of Community of Health Sciences, University of Calgary, Calgary, Alberta
Can J Cardiol 24:507-12. 2008..In 1999, the Canadian Hypertension Education Program (CHEP) was launched to develop and implement evidence-based hypertension guidelines...
Antihypertensive therapy and incidence of type 2 diabetes in an elderly cohortRaj Padwal
Division of General Internal Medicine, University of Alberta, Edmonton, Canada
Diabetes Care 27:2458-63. 2004..The aim of this study was to determine whether the incidence of type 2 diabetes differed among elderly users of four major antihypertensive drug classes...
The impact of the Canadian Hypertension Education Program on antihypertensive prescribing trendsNorman R C Campbell
Department of Medicine, University of Calgary, Calgary, Canada
Hypertension 47:22-8. 2006....
Antihypertensive medication prescribing in 27,822 elderly Canadians with diabetes over the past decadeFinlay A McAlister
Department of Medicine, University of Alberta, Edmonton, Alberta T6G 2R7, Canada
Diabetes Care 29:836-41. 2006..The purpose of this study was to examine whether prescribing practices for elderly individuals with diabetes and hypertension changed over the past decade...
Estimate of the benefits of a population-based reduction in dietary sodium additives on hypertension and its related health care costs in CanadaMichel R Joffres
Simon Fraser University, Burnaby, British Columbia, Canada
Can J Cardiol 23:437-43. 2007..Reductions in dietary sodium additives significantly lower systolic and diastolic blood pressure, and population reductions in dietary sodium are recommended by major scientific and public health organizations...
Polytherapy with two or more antihypertensive drugs to lower blood pressure in elderly Ontarians. Room for improvementNorman R C Campbell
Department of Medicine, Libin Cardiovascular Institute, University of Calgary, Calgary, AB, Canada
Can J Cardiol 23:783-7. 2007..Although guidelines now recommend polytherapy to achieve blood pressure targets, little is know about which antihypertensive drugs are combined in clinical practice...
Cardiovascular Health Awareness Program (CHAP): a community cluster-randomised trial among elderly CanadiansJanusz Kaczorowski
Department of Family Practice, University of British Columbia, Canada
Prev Med 46:537-44. 2008..The present study is a community cluster-randomised trial testing the effectiveness of CHAP (Cardiovascular Health Awareness Program) on the cardiovascular health of older adults...
Changes in prescribing patterns following publication of the ALLHAT trialPeter C Austin
JAMA 291:44-5. 2004
Prescriptions for estrogen replacement therapy in Ontario before and after publication of the Women's Health Initiative StudyPeter C Austin
JAMA 289:3241-2. 2003
A rural CT scanner: evaluating the effect on local health careBarbara J Merkens
Barbara Merkens and Associates, Don Mills, ON
Can Assoc Radiol J 57:224-31. 2006..We recommend that CT be expanded to other rural regions...
