J V Tu

Summary

Affiliation: Institute for Clinical Evaluative Sciences
Country: Canada

Publications

  1. pmc Identifying priorities in methodological research using ICD-9-CM and ICD-10 administrative data: report from an international consortium
    Carolyn De Coster
    Department of Community Health Sciences, University of Calgary, Calgary, Canada
    BMC Health Serv Res 6:77. 2006
  2. pmc Indicators of quality of care for patients with acute myocardial infarction
    Jack V Tu
    The Institute for Clinical Evaluative Sciences, Toronto, Ont
    CMAJ 179:909-15. 2008
  3. pmc Deriving ethnic-specific BMI cutoff points for assessing diabetes risk
    Maria Chiu
    Institute for Clinical Evaluative Sciences, Ontario, Canada
    Diabetes Care 34:1741-8. 2011
  4. doi request reprint A comparison of Chinese and non-Chinese Canadian patients hospitalized with heart failure
    Darwin F Yeung
    Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G250, Toronto ON, Canada
    BMC Cardiovasc Disord 13:114. 2013
  5. doi request reprint Best practices for developing cardiovascular quality indicators
    Jack V Tu
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada Division of Cardiology, Sunnybrook Schulich Heart Centre, Toronto, Ontario, Canada Department of Medicine, University of Toronto, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Electronic address
    Can J Cardiol 29:1516-9. 2013
  6. doi request reprint Standard admission orders can improve the management of acute myocardial infarction
    Lusine Abrahamyan
    Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G250, Toronto, Ontario, Canada
    Int J Qual Health Care 24:425-32. 2012
  7. pmc Determinants of variations in coronary revascularization practices
    Jack V Tu
    Institute for Clinical Evaluative Sciences, Toronto, Ont
    CMAJ 184:179-86. 2012
  8. pmc Surname lists to identify South Asian and Chinese ethnicity from secondary data in Ontario, Canada: a validation study
    Baiju R Shah
    Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue, Toronto, Ontario, M4N 3M5, Canada
    BMC Med Res Methodol 10:42. 2010
  9. pmc Impact of picture archiving communication systems on rates of duplicate imaging: a before-after study
    John J You
    Department of Medicine, McMaster University, 1200 Main Street West, HSC 3V51, Hamilton, Ontario, L8N 3Z5, Canada
    BMC Health Serv Res 8:234. 2008
  10. ncbi request reprint Assessing the outcomes of coronary artery bypass graft surgery: how many risk factors are enough? Steering Committee of the Cardiac Care Network of Ontario
    J V Tu
    Institute for Clinical Evaluative Sciences in Ontario, Sunnybrook Health Science Centre, North York, Canada
    J Am Coll Cardiol 30:1317-23. 1997

Detail Information

Publications110 found, 100 shown here

  1. pmc Identifying priorities in methodological research using ICD-9-CM and ICD-10 administrative data: report from an international consortium
    Carolyn De Coster
    Department of Community Health Sciences, University of Calgary, Calgary, Canada
    BMC Health Serv Res 6:77. 2006
    ..This paper presents a list of high-priority methodological areas for researchers using health administrative data...
  2. pmc Indicators of quality of care for patients with acute myocardial infarction
    Jack V Tu
    The Institute for Clinical Evaluative Sciences, Toronto, Ont
    CMAJ 179:909-15. 2008
    ..We undertook this initiative to develop an updated set of evidence-based indicators to measure and improve the quality of care for this patient population...
  3. pmc Deriving ethnic-specific BMI cutoff points for assessing diabetes risk
    Maria Chiu
    Institute for Clinical Evaluative Sciences, Ontario, Canada
    Diabetes Care 34:1741-8. 2011
    ..We compared the incidence rates of diabetes across white, South Asian, Chinese, and black populations and identified equivalent ethnic-specific BMI cutoff values for assessing diabetes risk...
  4. doi request reprint A comparison of Chinese and non-Chinese Canadian patients hospitalized with heart failure
    Darwin F Yeung
    Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G250, Toronto ON, Canada
    BMC Cardiovasc Disord 13:114. 2013
    ....
  5. doi request reprint Best practices for developing cardiovascular quality indicators
    Jack V Tu
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada Division of Cardiology, Sunnybrook Schulich Heart Centre, Toronto, Ontario, Canada Department of Medicine, University of Toronto, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Electronic address
    Can J Cardiol 29:1516-9. 2013
    ..Public release of the QI definitions and related performance data might help improve patient care quality and outcomes. ..
  6. doi request reprint Standard admission orders can improve the management of acute myocardial infarction
    Lusine Abrahamyan
    Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G250, Toronto, Ontario, Canada
    Int J Qual Health Care 24:425-32. 2012
    ..To evaluate whether the use of standard admission orders for patients admitted with acute myocardial infarction (AMI) is associated with better hospital quality of care...
  7. pmc Determinants of variations in coronary revascularization practices
    Jack V Tu
    Institute for Clinical Evaluative Sciences, Toronto, Ont
    CMAJ 184:179-86. 2012
    ..We conducted a comprehensive study to identify clinical and nonclinical factors associated with variations in the ratio across 17 cardiac centres in the province of Ontario...
  8. pmc Surname lists to identify South Asian and Chinese ethnicity from secondary data in Ontario, Canada: a validation study
    Baiju R Shah
    Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue, Toronto, Ontario, M4N 3M5, Canada
    BMC Med Res Methodol 10:42. 2010
    ..Surname lists are useful for identifying cohorts of ethnic minority patients from secondary data sources. This study sought to develop and validate lists to identify people of South Asian and Chinese origin...
  9. pmc Impact of picture archiving communication systems on rates of duplicate imaging: a before-after study
    John J You
    Department of Medicine, McMaster University, 1200 Main Street West, HSC 3V51, Hamilton, Ontario, L8N 3Z5, Canada
    BMC Health Serv Res 8:234. 2008
    ..Electronic health information systems, such as picture archiving communication systems (PACS), are commonly believed to reduce the need for duplicate testing. However, empirical data to support this belief are not available...
  10. ncbi request reprint Assessing the outcomes of coronary artery bypass graft surgery: how many risk factors are enough? Steering Committee of the Cardiac Care Network of Ontario
    J V Tu
    Institute for Clinical Evaluative Sciences in Ontario, Sunnybrook Health Science Centre, North York, Canada
    J Am Coll Cardiol 30:1317-23. 1997
    ..We sought to determine whether more comprehensive risk-adjustment models have a significant impact on hospital risk-adjusted mortality rates after coronary artery bypass graft surgery (CABG) in Ontario, Canada...
  11. ncbi request reprint Impracticability of informed consent in the Registry of the Canadian Stroke Network
    Jack V Tu
    Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
    N Engl J Med 350:1414-21. 2004
    ..However, the effect of such a requirement on the use of clinical registries and the extent to which registry data can be generalized remain uncertain...
  12. ncbi request reprint Risk factors for death or stroke after carotid endarterectomy: observations from the Ontario Carotid Endarterectomy Registry
    Jack V Tu
    Institute for Clinical Evaluative Sciences, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    Stroke 34:2568-73. 2003
    ..The purpose of this study was to identify preoperative patient risk factors for adverse outcomes (death or nonfatal stroke) after carotid endarterectomy through the use of a large population-based registry from Ontario, Canada...
  13. ncbi request reprint Outcomes of acute myocardial infarction in Canada
    Jack V Tu
    Sunnybrook and Women s College Health Sciences Centre, Toronto, Canada
    Can J Cardiol 19:893-901. 2003
    ..Little information is available on recent population-based trends in the outcomes of patients who have had an acute myocardial infarction (AMI) in Canada...
  14. ncbi request reprint Trends in treatment and outcomes for acute stroke patients in Ontario, 1992-1998
    Jack V Tu
    Institute for Clinical Evaluative Sciences, G106 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5
    Arch Intern Med 163:293-7. 2003
    ..The purpose of this study was to evaluate temporal trends in the characteristics, treatments, and outcomes of acute stroke patients in the province of Ontario...
  15. ncbi request reprint Introduction to the Canadian Cardiovascular Outcomes Research Team's (CCORT) Canadian Cardiovascular Atlas project
    Jack V Tu
    Institute for Clinical Evaluative Sciences and Department of Medicine, Sunnybrook and Women s College of Health Sciences, University of Toronto, Ontario
    Can J Cardiol 19:225-9. 2003
    ..This article serves as an introduction to the Atlas project and describes the rationale for and objectives of the CCORT national cardiac Atlas project...
  16. ncbi request reprint Impact of an acute myocardial infarction report card in Ontario, Canada
    Jack V Tu
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Int J Qual Health Care 15:131-7. 2003
    ..eds), 1999, Toronto: ICES), the first report featuring hospital-specific AMI performance measures to be published in Canada...
  17. ncbi request reprint Relationship between annual volume of patients treated by admitting physician and mortality after acute myocardial infarction
    J V Tu
    Institute for Clinical Evaluative Sciences, G 106, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5
    JAMA 285:3116-22. 2001
    ..Acute myocardial infarction (AMI) is a common condition that is treated by physicians with varying levels of clinical experience, but whether the level of experience affects outcome remains uncertain...
  18. ncbi request reprint Effectiveness and safety of drug-eluting stents in Ontario
    Jack V Tu
    Institute for Clinical Evaluative Sciences, Toronto, Ont, Canada
    N Engl J Med 357:1393-402. 2007
    ..However, there is uncertainty about the effectiveness of drug-eluting stents, and increasing concern about their safety, in routine clinical practice...
  19. doi request reprint Effectiveness of public report cards for improving the quality of cardiac care: the EFFECT study: a randomized trial
    Jack V Tu
    Institute for Clinical Evaluative Sciences, G106 2075 Bayview Ave, Toronto, ON M4N 3M5, Canada
    JAMA 302:2330-7. 2009
    ..Publicly released report cards on hospital performance are increasingly common, but whether they are an effective method for improving quality of care remains uncertain...
  20. pmc National trends in rates of death and hospital admissions related to acute myocardial infarction, heart failure and stroke, 1994-2004
    Jack V Tu
    Institute for Clinical Evaluative Sciences, Toronto, Ont
    CMAJ 180:E118-25. 2009
    ..We examined recent national trends in mortality and rates of hospital admission for these 3 conditions...
  21. ncbi request reprint Development and validation of the Ontario acute myocardial infarction mortality prediction rules
    J V Tu
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    J Am Coll Cardiol 37:992-7. 2001
    ..To develop and validate simple statistical models that can be used with hospital discharge administrative databases to predict 30-day and one-year mortality after an acute myocardial infarction (AMI)...
  22. ncbi request reprint Sex differences in carotid endarterectomy outcomes: results from the Ontario Carotid Endarterectomy Registry
    Moira K Kapral
    Institute for Clinical Evaluative Sciences, Division of General Internal Medicine and Clinical Epidemiology and Women s Health Program, University Health Network, Toronto, Ontario, Canada
    Stroke 34:1120-5. 2003
    ..We used data from a large population-based carotid surgery registry to determine whether sex differences exist in the risk of perioperative complications from carotid endarterectomy...
  23. ncbi request reprint Inhaled corticosteroids and the risk of mortality and readmission in elderly patients with chronic obstructive pulmonary disease
    D D Sin
    The Institute for Clinical Evaluative Sciences and The Department of Medicine, Sunnybrook and Women s College Health Science Center, University of Toronto, Toronto, Ontario, Canada
    Am J Respir Crit Care Med 164:580-4. 2001
    ....
  24. doi request reprint Age disparities in stroke quality of care and delivery of health services
    Gustavo Saposnik
    Stroke Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Stroke 40:3328-35. 2009
    ..Limited information is available on the effect of age on stroke management and care delivery. Our aim was to determine whether access to stroke care, delivery of health services, and clinical outcomes after stroke are affected by age...
  25. ncbi request reprint Regional variations in cardiovascular mortality in Canada
    Woganee A Filate
    Department of Public Health Sciences, University of Toronto, Toronto, Canada
    Can J Cardiol 19:1241-8. 2003
    ..However, no studies to date have explored the relationship between a number of health region characteristics and regional variation in heart disease mortality rates across Canada...
  26. ncbi request reprint Care and outcomes of patients newly hospitalized for heart failure in the community treated by cardiologists compared with other specialists
    Philip Jong
    Heart and Stroke Richard Lewar Centre of Excellence, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
    Circulation 108:184-91. 2003
    ..It is not known whether subspecialty care by cardiologists improves outcomes in heart failure patients from the community over care by other physicians...
  27. pmc Validation of the Thrombolysis In Myocardial Infarction (TIMI) risk index for predicting early mortality in a population-based cohort of STEMI and non-STEMI patients
    Pamela J Bradshaw
    Institute for Clinical Evaluative Sciences, Toronto, Canada
    Can J Cardiol 23:51-6. 2007
    ..It has not been tested in a population outside the United States or among non-STEMI patients...
  28. ncbi request reprint CCORT/CCS quality indicators for congestive heart failure care
    Douglas S Lee
    University of Toronto, Toronto, Canada
    Can J Cardiol 19:357-64. 2003
    ..Quality indicators are measurement tools for assessing the structure, processes and outcomes of care. Although quality indicators have been developed in other countries, Canadian cardiovascular disease indicators do not exist...
  29. pmc Comparison of cardiovascular risk profiles among ethnic groups using population health surveys between 1996 and 2007
    Maria Chiu
    Institute for Clinical Evaluative Sciences, Toronto, Ont
    CMAJ 182:E301-10. 2010
    ..We conducted a large, population-based comparison of cardiovascular risk among people of white, South Asian, Chinese and black ethnicity living in Ontario, Canada...
  30. ncbi request reprint Quality of care of international and Canadian medical graduates in acute myocardial infarction
    Dennis T Ko
    Division of Cardiology and Schulich Heart Centre, Sunnybrook and Women s College Health Sciences Centre, Ontario, Canada
    Arch Intern Med 165:458-63. 2005
    ..There are concerns that IMGs may provide inferior medical care compared with locally trained medical graduates, but that has not been established...
  31. ncbi request reprint Comparing hierarchical modeling with traditional logistic regression analysis among patients hospitalized with acute myocardial infarction: should we be analyzing cardiovascular outcomes data differently?
    Peter C Austin
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Am Heart J 145:27-35. 2003
    ..Furthermore, imputing characteristics measured at higher levels of the hierarchy to the patient-level artificially inflates the amount of available information on the effect of higher-level characteristics on outcomes...
  32. ncbi request reprint Regional variation in self-reported heart disease prevalence in Canada
    Chi Ming Chow
    Division of Cardiology, St Michael s Hospital, University of Toronto, Toronto, Ontario
    Can J Cardiol 21:1265-71. 2005
    ..Cardiovascular disease is the leading cause of death in Canada...
  33. ncbi request reprint Prognosis and determinants of survival in patients newly hospitalized for heart failure: a population-based study
    Philip Jong
    Heart and Stroke Richard Lewar Centre of Excellence and the Toronto General Hospital, University Health Network, Ontario, Canada
    Arch Intern Med 162:1689-94. 2002
    ..The prognosis in unselected community-dwelling patients with heart failure has not been widely studied...
  34. ncbi request reprint Effect of age on the use of evidence-based therapies for acute myocardial infarction
    Chau T T Tran
    University of Toronto, Institute of Medical Sciences, Toronto, Ontario, Canada
    Am Heart J 148:834-41. 2004
    ..The objective of this study was to determine whether elderly patients are less likely than non-elderly patients to receive evidence-based AMI treatments, both before and after the consideration of contraindications to therapy...
  35. pmc Mid-term outcomes of off-pump versus on-pump coronary artery bypass graft surgery
    Joan Ivanov
    Division of Cardiology, University Health Network Toronto General Hospital, Toronto, Ontario
    Can J Cardiol 24:279-84. 2008
    ..To evaluate survival and readmissions to hospital for cardiac events or coronary revascularization (REVASC) in patients having off-pump (OPCAB) versus conventional on-pump (CCAB) coronary artery bypass graft surgery (CABG)...
  36. ncbi request reprint Gender differences in outcomes after hospital discharge from coronary artery bypass grafting
    Veena Guru
    Institute for Clinical Evaluative Sciences, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Canada
    Circulation 113:507-16. 2006
    ..This study compares gender differences in cardiac events in a population of hospital survivors up to 11 years after isolated CABG surgery in Ontario, Canada...
  37. ncbi request reprint Long-term MI outcomes at hospitals with or without on-site revascularization
    D A Alter
    Institute for Clinical Evaluative Sciences, G106 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5
    JAMA 285:2101-8. 2001
    ..Whether such differences are due to invasive procedure rates alone or to other patient, physician, and hospital characteristics is unknown...
  38. pmc Use of beta-blocker therapy in older patients after acute myocardial infarction in Ontario
    P A Rochon
    Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Toronto, Ont
    CMAJ 161:1403-8. 1999
    ..The objectives of this study were to identify undertreated groups of seniors and to determine whether older and frailer patients are being selectively dispensed low-dose beta-blocker therapy...
  39. ncbi request reprint Age- and gender-related use of low-dose drug therapy: the need to manufacture low-dose therapy and evaluate the minimum effective dose
    P A Rochon
    Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, University of Toronto, Ontario, Canada
    J Am Geriatr Soc 47:954-9. 1999
    ....
  40. ncbi request reprint Underuse of inhaled steroid therapy in elderly patients with asthma
    D D Sin
    Department of Medicine, Sunnybrook and Women s College Health Science Center, University of Toronto, Toronto, Ontario, Canada
    Chest 119:720-5. 2001
    ....
  41. ncbi request reprint Statin use and survival outcomes in elderly patients with heart failure
    Joel G Ray
    Department of Medicine, St Michaels Hospital, University of Toronto, Ontario M5B 1W8, Canada
    Arch Intern Med 165:62-7. 2005
    ..Coronary artery disease is a leading cause of heart failure. Statins are efficacious drugs for the primary and secondary prevention of coronary heart disease, but their value in persons with heart failure remains unknown...
  42. doi request reprint Potentially preventable strokes in high-risk patients with atrial fibrillation who are not adequately anticoagulated
    David J Gladstone
    FRCPC, Director, Regional Stroke Prevention Clinic, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room A442, Toronto, Ontario, Canada
    Stroke 40:235-40. 2009
    ..This study examined the magnitude of this problem in a large contemporary, prospective stroke registry...
  43. pmc Use of angiotensin-converting enzyme inhibitor therapy and dose-related outcomes in older adults with new heart failure in the community
    Paula A Rochon
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    J Gen Intern Med 19:676-83. 2004
    ..To evaluate the dose-related benefit of angiotensin-converting enzyme (ACE) inhibitor therapy among older adults with heart failure and to evaluate whether low-dose ACE inhibitor therapy is better than none...
  44. doi request reprint Evaluating sex differences in population-based utilization of implantable cardioverter-defibrillators: role of cardiac conditions and noncardiac comorbidities
    Derek R MacFadden
    Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    Heart Rhythm 6:1289-96. 2009
    ..The influence of age and comorbidities on sex-specific implantable cardioverter-defibrillator (ICD) use for primary or secondary prevention is undefined...
  45. ncbi request reprint A comparison of a Bayesian vs. a frequentist method for profiling hospital performance
    P C Austin
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    J Eval Clin Pract 7:35-45. 2001
    ....
  46. pmc Utilisation of coronary angiography after acute myocardial infarction in Ontario over time: have referral patterns changed?
    Y Khaykin
    Division of Cardiology, Schulich Heart Centre, Sunnybrook and Women s College Health Sciences Centre and the University of Toronto, Toronto, Ontario, Canada
    Heart 88:460-6. 2002
    ..To examine how physicians in Ontario, Canada, have altered their referral patterns for coronary angiography after acute myocardial infarction (AMI) over time...
  47. ncbi request reprint Time-related mortality for women after coronary artery bypass graft surgery: a population-based study
    Veena Guru
    Institute for Clinical Evaluative Sciences, and Division of Cardiovascular Surgery, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 127:1158-65. 2004
    ..This study explores the relative early and late mortality risks in women and men after coronary artery bypass graft surgery...
  48. ncbi request reprint Effect of socioeconomic status on treatment and mortality after stroke
    Moira K Kapral
    Institute for Clinical Evaluative Sciences, University Health Network University of Toronto, Ontario, Canada
    Stroke 33:268-73. 2002
    ..Socioeconomic status is associated with increased mortality from ischemic heart disease. We undertook a study to determine whether a similar association exists between socioeconomic status and stroke mortality...
  49. pmc Management and outcomes of transient ischemic attacks in Ontario
    David J Gladstone
    Division of Neurology, Department of Medicine, and the Regional Stroke Centre, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ont
    CMAJ 170:1099-104. 2004
    ..We studied prospectively a cohort of consecutive patients presenting with TIA to the emergency department of 4 regional stroke centres in Ontario...
  50. doi request reprint Paclitaxel versus sirolimus stents in diabetic and nondiabetic patients
    Maria Chiu
    Institute for Clinical Evaluative Sciences, Toronto, Canada
    Circ Cardiovasc Qual Outcomes 2:96-107. 2009
    ..We therefore studied the long-term effectiveness and safety of sirolimus versus paclitaxel stents overall and stratified by the absence or presence of diabetes...
  51. ncbi request reprint International experience in stroke registries: lessons learned in establishing the Registry of the Canadian Stroke Network
    Frank L Silver
    Division of Neurology, University of Toronto, Toronto, Ontario, Canada
    Am J Prev Med 31:S235-7. 2006
    ..The need for stroke registries to collect accurate data that are representative of all patients with acute stroke in a given community is emphasized, and how the current methodology strives to reach this goal is outlined...
  52. pmc Dihydropyridine calcium channel blockers and cardiovascular outcomes in elderly patients: a population-based study
    Claudia Bucci
    Department of Pharmacie, Sunnybook Health Sciences Centre, University of Toronto, Ontario, Canada
    Can J Cardiol 24:629-32. 2008
    ..Despite safety concerns associated with short-acting agents, increasing evidence supports the safety of long-acting dihydropyridines. Although amlodipine is the best studied of these, there are few studies comparing it with nifedipine...
  53. pmc Problems for clinical judgement: 2. Obtaining a reliable past medical history
    D A Redelmeier
    Department of Medicine, University of Toronto, Toronto, Ont
    CMAJ 164:809-13. 2001
    ..An awareness of these specific human fallibilities might help clinicians avoid some errors when eliciting a patient's past medical history...
  54. ncbi request reprint Recent trends in cardiovascular complications among men and women with and without diabetes
    Gillian L Booth
    Department of Medicine, University of Toronto, Ontario, Canada
    Diabetes Care 29:32-7. 2006
    ..To compare recent trends in cardiovascular disease (CVD) outcomes among men and women with diabetes with those in the nondiabetic population...
  55. ncbi request reprint Outcome of heart failure with preserved ejection fraction in a population-based study
    R Sacha Bhatia
    Heart and Stroke Richard Lewar Centre of Excellence, University of Toronto, and the Division of Cardiology, Toronto General Hospital, University Health Network, Toronto, ON, Canada
    N Engl J Med 355:260-9. 2006
    ....
  56. doi request reprint Prevalence, predictors, and outcomes of primary nonadherence after acute myocardial infarction
    Cynthia A Jackevicius
    University Health Network and Department of Health Policy, Management, and Evaluation, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
    Circulation 117:1028-36. 2008
    ..Our objectives were to characterize, to determine factors of, and to measure outcomes associated with primary nonadherence after AMI...
  57. ncbi request reprint Health outcomes categorized by current and previous definitions of acute myocardial infarction in an unselected cohort of troponin-naïve emergency department patients
    Peter A Kavsak
    Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada, and Department of Pathology, Women and Infants Hospital of Rhode Island, Providence, USA
    Clin Chem 52:2028-35. 2006
    ..The health outcomes were based on the WHO definition and occurred in an era that preceded the use of cardiac troponin biomarkers...
  58. pmc The real-world outcomes of off-pump coronary artery bypass surgery in a public health care system
    Veena Guru
    Institute for Clinical Evaluative Sciences, Division of Cardiovascular Surgery, University of Toronto, Ontario
    Can J Cardiol 23:281-6. 2007
    ..The population-based results of off-pump coronary artery bypass surgery (OPCAB) in a public health care system have not been reported...
  59. doi request reprint Temporal trends in the use of percutaneous coronary intervention and coronary artery bypass surgery in New York State and Ontario
    Dennis T Ko
    Institute for Clinical Evaluative Sciences, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Department of Medicine, University of Toronto, Ontario, Canada
    Circulation 121:2635-44. 2010
    ..Although New York State (NYS) historically has had twice as many coronary revascularizations performed as Ontario, the relative evolution of coronary revascularization patterns in both jurisdictions over time is unknown...
  60. doi request reprint Statin therapy and clinical outcomes in heart failure: a propensity-matched analysis
    Maral Ouzounian
    Heart and Stroke Richard Lewar Centre for Excellence, University of Toronto, Toronto, Ontario, Canada
    J Card Fail 15:241-8. 2009
    ..The influence of statin therapy in heart failure (HF) has been of considerable interest. The objective of this study was to determine if statins are associated with improved outcomes in patients discharged after hospitalization for HF...
  61. ncbi request reprint Quality of care and outcomes of older patients with heart failure hospitalized in the United States and Canada
    Dennis T Ko
    Department of Cardiology, Schulich Heart Centre, Toronto, Ontario
    Arch Intern Med 165:2486-92. 2005
    ..We compared the process of care and outcomes of patients with heart failure, the most common cause of hospitalization for individuals 65 years and older in both countries...
  62. ncbi request reprint Risk-treatment mismatch in the pharmacotherapy of heart failure
    Douglas S Lee
    Institute for Clinical Evaluative Sciences, Department of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada
    JAMA 294:1240-7. 2005
    ..Patients with heart failure have a wide spectrum of mortality risks. To maximize the benefit of available pharmacotherapies, patients with high mortality risk should receive high rates of drug therapy...
  63. ncbi request reprint Comparison of coding of heart failure and comorbidities in administrative and clinical data for use in outcomes research
    Douglas S Lee
    Institute for Clinical Evaluative Sciences, Toronto, Canada
    Med Care 43:182-8. 2005
    ..Despite the potential usefulness of administrative databases for evaluating outcomes, coding of heart failure and associated comorbidities have not been definitively compared with clinical data...
  64. ncbi request reprint Trends in heart failure outcomes and pharmacotherapy: 1992 to 2000
    Douglas S Lee
    Faculty of Pharmacy, Toronto, Canada
    Am J Med 116:581-9. 2004
    ..To review trends in drug therapy and concomitant outcomes of elderly heart failure patients in Ontario, Canada...
  65. ncbi request reprint Biology or bias: practice patterns and long-term outcomes for men and women with acute myocardial infarction
    D A Alter
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    J Am Coll Cardiol 39:1909-16. 2002
    ..Another objective was to evaluate the association of age, gender and treatment intensity with five-year survival after AMI...
  66. pmc Problems for clinical judgement: 3. Thinking clearly in an emergency
    M J Schull
    Division of Emergency Medicine, University of Toronto, Toronto, Ont
    CMAJ 164:1170-5. 2001
    ..Better training and teamwork may allow for clearer thinking in emergencies, so that knowledge can be translated into effective action and better patient outcomes...
  67. pmc Validity of the GRACE (Global Registry of Acute Coronary Events) acute coronary syndrome prediction model for six month post-discharge death in an independent data set
    P J Bradshaw
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Heart 92:905-9. 2006
    ....
  68. pmc Publicly reported provider outcomes: the concerns of cardiac surgeons in a single-payer system
    Veena Guru
    Institute for Clinival Evaluative Sciences, University of Toronto, Toronto, Ontario, Canada
    Can J Cardiol 25:33-8. 2009
    ..Provider outcomes reports are an important part of quality improvement efforts. The positive and negative impact of such reports on the delivery of care has not been extensively explored...
  69. ncbi request reprint Long-term health outcomes associated with detectable troponin I concentrations
    Peter A Kavsak
    Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada
    Clin Chem 53:220-7. 2007
    ..We designed this study to extend this observation by examining risk prediction in both men and women presenting to an emergency department with chest discomfort...
  70. ncbi request reprint Developing risk-adjusted 30-day hospital mortality rates
    Ann E Tourangeau
    Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada
    Res Nurs Health 26:483-96. 2003
    ..This procedure is useful for developing risk-adjusted outcomes with administrative data similar to those used in this study...
  71. ncbi request reprint An overview of the methods and data used in the CCORT Canadian Cardiovascular Atlas project
    Courtney C Kennedy
    Institute for Clinical Evaluative Sciences, Toronto, Canada
    Can J Cardiol 19:655-63. 2003
    ....
  72. ncbi request reprint Do operator volumes relate to clinical outcomes after percutaneous coronary intervention in the Canadian health care system?
    Warren J Cantor
    University of Toronto, Toronto, Ontario, Canada
    Am Heart J 151:902-8. 2006
    ..No study has assessed whether this relationship exists in Canada, where PCI is performed only at a limited number of regional centers and operator volumes are higher...
  73. doi request reprint Association of temporal trends in risk factors and treatment uptake with coronary heart disease mortality, 1994-2005
    Harindra C Wijeysundera
    Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    JAMA 303:1841-7. 2010
    ..Coronary heart disease (CHD) mortality has declined substantially in Canada since 1994...
  74. ncbi request reprint Regional outcomes of heart failure in Canada
    Douglas S Lee
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Can J Cardiol 20:599-607. 2004
    ..Heart failure is a condition associated with significant mortality and morbidity. However, demographic features and outcomes following hospitalization for heart failure, and associated regional comparisons have not been performed in Canada...
  75. ncbi request reprint CCORT/CCS quality indicators for acute myocardial infarction care
    Chau T T Tran
    Institute for Clinical Evaluative Sciences, Toronto, Ontario
    Can J Cardiol 19:38-45. 2003
    ..The authors' goal was to develop a set of Canadian quality indicators for AMI care...
  76. doi request reprint Relationship between preventability of death after coronary artery bypass graft surgery and all-cause risk-adjusted mortality rates
    Veena Guru
    Institute for Clinical Evaluative Sciences, G 106, 2075 Bayview Ave, Toronto, Ontario M4N 3M5 Canada
    Circulation 117:2969-76. 2008
    ....
  77. ncbi request reprint Adherence with statin therapy in elderly patients with and without acute coronary syndromes
    Cynthia A Jackevicius
    Department of Health Policy, Management, and Evaluation, Pharmacy Department and Women s Health Program, University Health Network Toronto General Hospital, 200 Elizabeth St, Toronto, Ontario, Canada M5G 2C4
    JAMA 288:462-7. 2002
    ..Research prior to these trials of older lipid-lowering agents demonstrated low levels of 1-year adherence...
  78. pmc Problems for clinical judgement: 1. Eliciting an insightful history of present illness
    D A Redelmeier
    Department of Medicine, University of Toronto, Toronto, Ont
    CMAJ 164:647-51. 2001
    ..These insights might help clinicians avoid mistakes when eliciting a patient's history of present illness...
  79. ncbi request reprint The influence of surgical specialty training on the outcomes of elective abdominal aortic aneurysm surgery
    J V Tu
    Institute for Clinical Evaluative Sciences (ICES, the Division of General Internal Medicine and Clinical Epidemiology and Health Care Research Program at Sunnybrook and Women's College Health Science Centre, University of Toronto, Canada
    J Vasc Surg 33:447-52. 2001
    ..These results provide evidence that surgical specialty training in vascular procedures leads to better patient outcomes...
  80. ncbi request reprint Investigating the determinants of decreasing postmyocardial infarction mortality: an analysis of in-hospital data from 1992 and 1997
    N Daneman
    Department of Medicine, University of Toronto, Toronto, Canada
    Can J Cardiol 17:771-6. 2001
    ..The increased use of evidence-based pharmacotherapy may be the most significant contributing factor to declining postmyocardial infarction mortality...
  81. ncbi request reprint Use of the statins in patients after acute myocardial infarction: does evidence change practice?
    C A Jackevicius
    Pharmacy Department, University Health Network Toronto General Hospital, 200 Elizabeth St, Toronto, Ontario, Canada M5G 2C4
    Arch Intern Med 161:183-8. 2001
    ....
  82. ncbi request reprint Outpatient antibiotic therapy and short term mortality in elderly patients with chronic obstructive pulmonary disease
    D D Sin
    Sunnybrook and Women s College Health Science Centre, University of Toronto, Toronto, Canada
    Can Respir J 7:466-71. 2000
    ..To determine the association between outpatient use of oral antibiotics and 30-day all-cause mortality following hospitalization in a group of elderly chronic obstructive pulmonary disease (COPD) patients...
  83. ncbi request reprint Hypertension guidelines in elderly patients: is anybody listening?
    Karen Tu
    Institute for Clinical Evaluative Services, G106 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
    Am J Med 113:52-8. 2002
    ....
  84. ncbi request reprint Stroke care delivery in institutions participating in the Registry of the Canadian Stroke Network
    Moira K Kapral
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Stroke 35:1756-62. 2004
    ..Guidelines and performance indicators have been established for acute stroke care. However, little is known about the process of stroke care delivery in Canada...
  85. ncbi request reprint The evaluation of a formalized queue management system for coronary angiography waiting lists
    D A Alter
    Institute for Clinical Evaluative Sciences, Toronto, Canada
    Can J Cardiol 21:1203-9. 2005
    ..The extent to which formal queue management systems may improve the prioritization and survival of patients in the angiography queue is unknown...
  86. doi request reprint Association of blood pressure at hospital discharge with mortality in patients diagnosed with heart failure
    Douglas S Lee
    Institute for Clinical Evaluative Sciences, Ontario, Canada
    Circ Heart Fail 2:616-23. 2009
    ..Higher blood pressure in acute heart failure has been associated with improved survival; however, the relationship between blood pressure and survival in stabilized patients at hospital discharge has not been established...
  87. ncbi request reprint One-year outcome of patients after acute coronary syndromes (from the Canadian Acute Coronary Syndromes Registry)
    Andrew T Yan
    Terrence Donnelly Heart Centre, Division of Cardiology, St Michael s Hospital, University of Toronto, Ontario, Canada
    Am J Cardiol 94:25-9. 2004
    ..Moreover, there was a significant opportunity to enhance the discharge and long-term use of evidence-based secondary prevention therapies...
  88. doi request reprint Emergency department triage of acute myocardial infarction patients and the effect on outcomes
    Clare L Atzema
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Ann Emerg Med 53:736-45. 2009
    ....
  89. ncbi request reprint Missed opportunities in the secondary prevention of myocardial infarction: an assessment of the effects of statin underprescribing on mortality
    Peter C Austin
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Am Heart J 151:969-75. 2006
    ..We explored the potential reduction in mortality at the population level that could result from improving statin prescribing among patients least likely to be prescribed a statin after acute myocardial infarction (AMI)...
  90. pmc Development and validation of the Osteoporosis Risk Assessment Instrument to facilitate selection of women for bone densitometry
    S M Cadarette
    Canadian Multicentre Osteoporosis Study, University of Toronto, Ont
    CMAJ 162:1289-94. 2000
    ..The objective of this study was to develop and validate a clinical tool to help clinicians identify which women are at increased risk for osteoporosis and should therefore undergo further testing with bone densitometry...
  91. ncbi request reprint Myocardial infarction and the validation of physician billing and hospitalization data using electronic medical records
    K Tu
    Institute for Clinical Evaluative Sciences ICES, Toronto, Canada
    Chronic Dis Can 30:141-6. 2010
    ..We set out to determine if adding physician billing data to hospital discharge data would result in an accurate capture of patients who have had a myocardial infarction...
  92. ncbi request reprint Nursing-related determinants of 30-day mortality for hospitalized patients
    A E Tourangeau
    Faculty of Nursing, University of Toronto, Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Can J Nurs Res 33:71-88. 2002
    ..These findings can be used to predict the effects of hospital changes in nursing skill mix and years of RN experience on patient mortality...
  93. pmc Problems for clinical judgement: 4. Surviving in the report card era
    J V Tu
    Department of Medicine, University of Toronto, Toronto, Ont
    CMAJ 164:1709-12. 2001
    ..We offer a number of tips ranging from knowing your outcomes first to proactively getting involved in developing report cards...
  94. ncbi request reprint Inhaled corticosteroid therapy reduces the risk of rehospitalization and all-cause mortality in elderly asthmatics
    D D Sin
    Institute for Clinical Evaluation Sciences (ICES, Sunnybrook and Women's College Health Science Center, University of Toronto, Ontario, Canada
    Eur Respir J 17:380-5. 2001
    ..These findings suggest that inhaled corticosteroids are beneficial in reducing the risk for rehospitalization and all-cause mortality in elderly patients with asthma who have recently been hospitalized for their disease...
  95. ncbi request reprint Rate of stroke recurrence in patients with primary intracerebral hemorrhage
    M D Hill
    Toronto Western Hospital, University of Toronto, Division of Neurology, Ontario, Canada
    Stroke 31:123-7. 2000
    ..We sought to determine the rate of recurrence of ICH or cerebral ischemia in a cohort of PICH patients at the Toronto Hospital, Toronto, Canada...
  96. pmc Quality of congestive heart failure treatment at a Canadian teaching hospital
    E Weil
    Faculty of Medicine, University of Toronto, Toronto, Ont
    CMAJ 165:284-7. 2001
    ..INTERPRETATION: Most patients who had CHF at this Canadian hospital received left ventricular function testing and ACE inhibitor therapy. Future educational efforts should focus on the importance of adequate dosing of ACE inhibitors...
  97. ncbi request reprint Aspirin use and outcomes in a community-based cohort of 7352 patients discharged after first hospitalization for heart failure
    Finlay A McAlister
    Division of General Internal Medicine, University of Alberta, Edmonton, Canada
    Circulation 113:2572-8. 2006
    ....
  98. pmc Population rates of cardiac catheterization and yield of high-risk coronary artery disease
    Michelle M Graham
    Department of Medicine, University of Alberta, Edmonton
    CMAJ 173:35-9. 2005
    ..The optimal population rate of cardiac catheterization is unknown. One potential way to determine it would be to examine whether there is a population rate beyond which the yield of high-risk coronary artery disease (CAD) does not rise...
  99. ncbi request reprint Administrative Data Feedback for Effective Cardiac Treatment: AFFECT, a cluster randomized trial
    Christine A Beck
    Division of Clinical Epidemiology, McGill University Health Centre, Montreal, Quebec, Canada
    JAMA 294:309-17. 2005
    ..Hospital report cards are increasingly being implemented for quality improvement despite lack of strong evidence to support their use...
  100. pmc Effectiveness of statins for secondary prevention in elderly patients after acute myocardial infarction: an evaluation of class effect
    Zheng Zhou
    Department of Epidemiology and Biostatistics, McGill University, Montreal, Que
    CMAJ 172:1187-94. 2005
    ..However, it is unclear whether different statins exert a similar effect in reducing the incidence of recurrent AMI and death when used in clinical practice...
  101. ncbi request reprint Pharmacological treatment of congestive heart failure in Canada: a description of care in five provinces
    Jafna L Cox
    Department of Medicine, Dalhousie University, Halifax, Canada
    Can J Cardiol 21:337-43. 2005
    ..There have been major advances in the treatment of this condition over the past two decades, yet little information is currently available regarding the current status of CHF management in Canada...