Research Topics
| J V TuSummaryAffiliation: Institute for Clinical Evaluative Sciences Country: Canada Publications
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Detail Information
Publications
Identifying priorities in methodological research using ICD-9-CM and ICD-10 administrative data: report from an international consortiumCarolyn De Coster
Department of Community Health Sciences, University of Calgary, Calgary, Canada
BMC Health Serv Res 6:77. 2006..This paper presents a list of high-priority methodological areas for researchers using health administrative data...
Indicators of quality of care for patients with acute myocardial infarctionJack V Tu
The Institute for Clinical Evaluative Sciences, Toronto, Ont
CMAJ 179:909-15. 2008..We undertook this initiative to develop an updated set of evidence-based indicators to measure and improve the quality of care for this patient population...
Standard admission orders can improve the management of acute myocardial infarctionLusine Abrahamyan
Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue G250, Toronto, Ontario, Canada
Int J Qual Health Care 24:425-32. 2012..To evaluate whether the use of standard admission orders for patients admitted with acute myocardial infarction (AMI) is associated with better hospital quality of care...
Determinants of variations in coronary revascularization practicesJack V Tu
Institute for Clinical Evaluative Sciences, Toronto, Ont
CMAJ 184:179-86. 2012..We conducted a comprehensive study to identify clinical and nonclinical factors associated with variations in the ratio across 17 cardiac centres in the province of Ontario...
Surname lists to identify South Asian and Chinese ethnicity from secondary data in Ontario, Canada: a validation studyBaiju R Shah
Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue, Toronto, Ontario, M4N 3M5, Canada
BMC Med Res Methodol 10:42. 2010..Surname lists are useful for identifying cohorts of ethnic minority patients from secondary data sources. This study sought to develop and validate lists to identify people of South Asian and Chinese origin...
Impact of picture archiving communication systems on rates of duplicate imaging: a before-after studyJohn J You
Department of Medicine, McMaster University, 1200 Main Street West, HSC 3V51, Hamilton, Ontario, L8N 3Z5, Canada
BMC Health Serv Res 8:234. 2008..Electronic health information systems, such as picture archiving communication systems (PACS), are commonly believed to reduce the need for duplicate testing. However, empirical data to support this belief are not available...
Impact of an acute myocardial infarction report card in Ontario, CanadaJack V Tu
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Int J Qual Health Care 15:131-7. 2003..eds), 1999, Toronto: ICES), the first report featuring hospital-specific AMI performance measures to be published in Canada...
Trends in treatment and outcomes for acute stroke patients in Ontario, 1992-1998Jack V Tu
Institute for Clinical Evaluative Sciences, G106 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5
Arch Intern Med 163:293-7. 2003..The purpose of this study was to evaluate temporal trends in the characteristics, treatments, and outcomes of acute stroke patients in the province of Ontario...
Outcomes of acute myocardial infarction in CanadaJack V Tu
Sunnybrook and Women s College Health Sciences Centre, Toronto, Canada
Can J Cardiol 19:893-901. 2003..Little information is available on recent population-based trends in the outcomes of patients who have had an acute myocardial infarction (AMI) in Canada...
Risk factors for death or stroke after carotid endarterectomy: observations from the Ontario Carotid Endarterectomy RegistryJack V Tu
Institute for Clinical Evaluative Sciences, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
Stroke 34:2568-73. 2003..The purpose of this study was to identify preoperative patient risk factors for adverse outcomes (death or nonfatal stroke) after carotid endarterectomy through the use of a large population-based registry from Ontario, Canada...
Introduction to the Canadian Cardiovascular Outcomes Research Team's (CCORT) Canadian Cardiovascular Atlas projectJack V Tu
Institute for Clinical Evaluative Sciences and Department of Medicine, Sunnybrook and Women s College of Health Sciences, University of Toronto, Ontario
Can J Cardiol 19:225-9. 2003..This article serves as an introduction to the Atlas project and describes the rationale for and objectives of the CCORT national cardiac Atlas project...
Impracticability of informed consent in the Registry of the Canadian Stroke NetworkJack V Tu
Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
N Engl J Med 350:1414-21. 2004..However, the effect of such a requirement on the use of clinical registries and the extent to which registry data can be generalized remain uncertain...
Relationship between annual volume of patients treated by admitting physician and mortality after acute myocardial infarctionJ V Tu
Institute for Clinical Evaluative Sciences, G 106, 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5
JAMA 285:3116-22. 2001..Acute myocardial infarction (AMI) is a common condition that is treated by physicians with varying levels of clinical experience, but whether the level of experience affects outcome remains uncertain...
Assessing the outcomes of coronary artery bypass graft surgery: how many risk factors are enough? Steering Committee of the Cardiac Care Network of OntarioJ V Tu
Institute for Clinical Evaluative Sciences in Ontario, Sunnybrook Health Science Centre, North York, Canada
J Am Coll Cardiol 30:1317-23. 1997..We sought to determine whether more comprehensive risk-adjustment models have a significant impact on hospital risk-adjusted mortality rates after coronary artery bypass graft surgery (CABG) in Ontario, Canada...
National trends in rates of death and hospital admissions related to acute myocardial infarction, heart failure and stroke, 1994-2004Jack V Tu
Institute for Clinical Evaluative Sciences, Toronto, Ont
CMAJ 180:E118-25. 2009..We examined recent national trends in mortality and rates of hospital admission for these 3 conditions...
Effectiveness of public report cards for improving the quality of cardiac care: the EFFECT study: a randomized trialJack V Tu
Institute for Clinical Evaluative Sciences, G106 2075 Bayview Ave, Toronto, ON M4N 3M5, Canada
JAMA 302:2330-7. 2009..Publicly released report cards on hospital performance are increasingly common, but whether they are an effective method for improving quality of care remains uncertain...
Development and validation of the Ontario acute myocardial infarction mortality prediction rulesJ V Tu
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
J Am Coll Cardiol 37:992-7. 2001..To develop and validate simple statistical models that can be used with hospital discharge administrative databases to predict 30-day and one-year mortality after an acute myocardial infarction (AMI)...
Effectiveness and safety of drug-eluting stents in OntarioJack V Tu
Institute for Clinical Evaluative Sciences, Toronto, Ont, Canada
N Engl J Med 357:1393-402. 2007..However, there is uncertainty about the effectiveness of drug-eluting stents, and increasing concern about their safety, in routine clinical practice...
Sex differences in carotid endarterectomy outcomes: results from the Ontario Carotid Endarterectomy RegistryMoira K Kapral
Institute for Clinical Evaluative Sciences, Division of General Internal Medicine and Clinical Epidemiology and Women s Health Program, University Health Network, Toronto, Ontario, Canada
Stroke 34:1120-5. 2003..We used data from a large population-based carotid surgery registry to determine whether sex differences exist in the risk of perioperative complications from carotid endarterectomy...
Inhaled corticosteroids and the risk of mortality and readmission in elderly patients with chronic obstructive pulmonary diseaseD D Sin
The Institute for Clinical Evaluative Sciences and The Department of Medicine, Sunnybrook and Women s College Health Science Center, University of Toronto, Toronto, Ontario, Canada
Am J Respir Crit Care Med 164:580-4. 2001....
Age disparities in stroke quality of care and delivery of health servicesGustavo Saposnik
Stroke Research Unit, Division of Neurology, Department of Medicine, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
Stroke 40:3328-35. 2009..Limited information is available on the effect of age on stroke management and care delivery. Our aim was to determine whether access to stroke care, delivery of health services, and clinical outcomes after stroke are affected by age...
Care and outcomes of patients newly hospitalized for heart failure in the community treated by cardiologists compared with other specialistsPhilip Jong
Heart and Stroke/Richard Lewar Centre of Excellence, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada
Circulation 108:184-91. 2003..These data raise the need to identify specialty-driven differences in processes of care for heart failure patients, which may explain the observed disparity in clinical outcomes that presently favor cardiologist care...
Regional variations in cardiovascular mortality in CanadaWoganee A Filate
Department of Public Health Sciences, University of Toronto, Toronto, Canada
Can J Cardiol 19:1241-8. 2003..Efforts to reduce CVD and IHD mortality in Canada require attention to both traditional risk factors (eg, smoking) and broader determinants of health (eg, unemployment rates)...
Validation of the Thrombolysis In Myocardial Infarction (TIMI) risk index for predicting early mortality in a population-based cohort of STEMI and non-STEMI patientsPamela J Bradshaw
Institute for Clinical Evaluative Sciences, Toronto, Canada
Can J Cardiol 23:51-6. 2007..It has not been tested in a population outside the United States or among non-STEMI patients...
Comparison of cardiovascular risk profiles among ethnic groups using population health surveys between 1996 and 2007Maria Chiu
Institute for Clinical Evaluative Sciences, Toronto, Ont
CMAJ 182:E301-10. 2010..We conducted a large, population-based comparison of cardiovascular risk among people of white, South Asian, Chinese and black ethnicity living in Ontario, Canada...
CCORT/CCS quality indicators for congestive heart failure careDouglas S Lee
University of Toronto, Toronto, Canada
Can J Cardiol 19:357-64. 2003..These quality indicators will serve as a foundation for future studies evaluating the quality of CHF care in Canada...
Comparing hierarchical modeling with traditional logistic regression analysis among patients hospitalized with acute myocardial infarction: should we be analyzing cardiovascular outcomes data differently?Peter C Austin
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Am Heart J 145:27-35. 2003..Furthermore, imputing characteristics measured at higher levels of the hierarchy to the patient-level artificially inflates the amount of available information on the effect of higher-level characteristics on outcomes...
Quality of care of international and Canadian medical graduates in acute myocardial infarctionDennis T Ko
Division of Cardiology and Schulich Heart Centre, Sunnybrook and Women's College Health Sciences Centre, Ontario, Canada
Arch Intern Med 165:458-63. 2005..This information places the care provided by IMGs into perspective and supports the ability of well-selected IMGs in caring for AMI patients...
Prognosis and determinants of survival in patients newly hospitalized for heart failure: a population-based studyPhilip Jong
Heart and Stroke/Richard Lewar Centre of Excellence and the Toronto General Hospital, University Health Network, Ontario, Canada
Arch Intern Med 162:1689-94. 2002..Although age, sex, and comorbidities were confirmed to be independent prognostic indicators of heart failure, their complex interaction with survival should be considered in future studies...
Effect of age on the use of evidence-based therapies for acute myocardial infarctionChau T T Tran
University of Toronto, Institute of Medical Sciences, Toronto, Ontario, Canada
Am Heart J 148:834-41. 2004..46; 95% CI, 1.22-1.74). CONCLUSIONS: Despite adjustments for contraindications to therapy, the underuse of AMI treatments, particularly in elderly patients, was found...
Regional variation in self-reported heart disease prevalence in CanadaChi-Ming Chow
Division of Cardiology, St. Michael's Hospital, University of Toronto, Toronto, Ontario
Can J Cardiol 21:1265-71. 2005..These data may assist health system planners to identify those regions and population subgroups most affected by heart disease, and to support the development of heart disease prevention and treatment programs...
Mid-term outcomes of off-pump versus on-pump coronary artery bypass graft surgeryJoan Ivanov
Division of Cardiology, University Health Network Toronto General Hospital, Toronto, Ontario
Can J Cardiol 24:279-84. 2008..To evaluate survival and readmissions to hospital for cardiac events or coronary revascularization (REVASC) in patients having off-pump (OPCAB) versus conventional on-pump (CCAB) coronary artery bypass graft surgery (CABG)...
Gender differences in outcomes after hospital discharge from coronary artery bypass graftingVeena Guru
Institute for Clinical Evaluative Sciences, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Canada
Circulation 113:507-16. 2006..This study compares gender differences in cardiac events in a population of hospital survivors up to 11 years after isolated CABG surgery in Ontario, Canada...
Long-term MI outcomes at hospitals with or without on-site revascularizationD A Alter
Institute for Clinical Evaluative Sciences, G106 2075 Bayview Ave, Toronto, Ontario, Canada M4N 3M5
JAMA 285:2101-8. 2001..Whether such differences are due to invasive procedure rates alone or to other patient, physician, and hospital characteristics is unknown...
Underuse of inhaled steroid therapy in elderly patients with asthmaD D Sin
Department of Medicine, Sunnybrook and Women s College Health Science Center, University of Toronto, Toronto, Ontario, Canada
Chest 119:720-5. 2001....
Use of beta-blocker therapy in older patients after acute myocardial infarction in OntarioP A Rochon
Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Toronto, Ont
CMAJ 161:1403-8. 1999..The objectives of this study were to identify undertreated groups of seniors and to determine whether older and frailer patients are being selectively dispensed low-dose beta-blocker therapy...
Age- and gender-related use of low-dose drug therapy: the need to manufacture low-dose therapy and evaluate the minimum effective doseP A Rochon
Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, University of Toronto, Ontario, Canada
J Am Geriatr Soc 47:954-9. 1999....
Evaluating sex differences in population-based utilization of implantable cardioverter-defibrillators: role of cardiac conditions and noncardiac comorbiditiesDerek R MacFadden
Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Heart Rhythm 6:1289-96. 2009..The influence of age and comorbidities on sex-specific implantable cardioverter-defibrillator (ICD) use for primary or secondary prevention is undefined...
Potentially preventable strokes in high-risk patients with atrial fibrillation who are not adequately anticoagulatedDavid J Gladstone
FRCPC, Director, Regional Stroke Prevention Clinic, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Room A442, Toronto, Ontario, Canada
Stroke 40:235-40. 2009..This study examined the magnitude of this problem in a large contemporary, prospective stroke registry...
Statin use and survival outcomes in elderly patients with heart failureJoel G Ray
Department of Medicine, St Michaels Hospital, University of Toronto, Ontario M5B 1W8, Canada
Arch Intern Med 165:62-7. 2005..Coronary artery disease is a leading cause of heart failure. Statins are efficacious drugs for the primary and secondary prevention of coronary heart disease, but their value in persons with heart failure remains unknown...
Use of angiotensin-converting enzyme inhibitor therapy and dose-related outcomes in older adults with new heart failure in the communityPaula A Rochon
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
J Gen Intern Med 19:676-83. 2004..To evaluate the dose-related benefit of angiotensin-converting enzyme (ACE) inhibitor therapy among older adults with heart failure and to evaluate whether low-dose ACE inhibitor therapy is better than none...
A comparison of a Bayesian vs. a frequentist method for profiling hospital performanceP C Austin
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
J Eval Clin Pract 7:35-45. 2001....
Utilisation of coronary angiography after acute myocardial infarction in Ontario over time: have referral patterns changed?Y Khaykin
Division of Cardiology, Schulich Heart Centre, Sunnybrook and Women s College Health Sciences Centre and the University of Toronto, Toronto, Ontario, Canada
Heart 88:460-6. 2002..To examine how physicians in Ontario, Canada, have altered their referral patterns for coronary angiography after acute myocardial infarction (AMI) over time...
Paclitaxel versus sirolimus stents in diabetic and nondiabetic patientsMaria Chiu
Institute for Clinical Evaluative Sciences, Toronto, Canada
Circ Cardiovasc Qual Outcomes 2:96-107. 2009..We therefore studied the long-term effectiveness and safety of sirolimus versus paclitaxel stents overall and stratified by the absence or presence of diabetes...
International experience in stroke registries: lessons learned in establishing the Registry of the Canadian Stroke NetworkFrank L Silver
Division of Neurology, University of Toronto, Toronto, Ontario, Canada
Am J Prev Med 31:S235-7. 2006..The need for stroke registries to collect accurate data that are representative of all patients with acute stroke in a given community is emphasized, and how the current methodology strives to reach this goal is outlined...
Management and outcomes of transient ischemic attacks in OntarioDavid J Gladstone
Division of Neurology, Department of Medicine, and the Regional Stroke Centre, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ont
CMAJ 170:1099-104. 2004..We studied prospectively a cohort of consecutive patients presenting with TIA to the emergency department of 4 regional stroke centres in Ontario...
Dihydropyridine calcium channel blockers and cardiovascular outcomes in elderly patients: a population-based studyClaudia Bucci
Department of Pharmacie, Sunnybook Health Sciences Centre, University of Toronto, Ontario, Canada
Can J Cardiol 24:629-32. 2008..Despite safety concerns associated with short-acting agents, increasing evidence supports the safety of long-acting dihydropyridines. Although amlodipine is the best studied of these, there are few studies comparing it with nifedipine...
Effect of socioeconomic status on treatment and mortality after strokeMoira K Kapral
Institute for Clinical Evaluative Sciences, University Health Network University of Toronto, Ontario, Canada
Stroke 33:268-73. 2002..Socioeconomic status is associated with increased mortality from ischemic heart disease. We undertook a study to determine whether a similar association exists between socioeconomic status and stroke mortality...
Time-related mortality for women after coronary artery bypass graft surgery: a population-based studyVeena Guru
Institute for Clinical Evaluative Sciences, and Division of Cardiovascular Surgery, Sunnybrook and Women s College Health Sciences Centre, Toronto, Ontario, Canada
J Thorac Cardiovasc Surg 127:1158-65. 2004..This study explores the relative early and late mortality risks in women and men after coronary artery bypass graft surgery...
Problems for clinical judgement: 2. Obtaining a reliable past medical historyD A Redelmeier
Department of Medicine, University of Toronto, Toronto, Ont
CMAJ 164:809-13. 2001..An awareness of these specific human fallibilities might help clinicians avoid some errors when eliciting a patient's past medical history...
Temporal trends in the use of percutaneous coronary intervention and coronary artery bypass surgery in New York State and OntarioDennis T Ko
Institute for Clinical Evaluative Sciences, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Department of Medicine, University of Toronto, Ontario, Canada
Circulation 121:2635-44. 2010..Although New York State (NYS) historically has had twice as many coronary revascularizations performed as Ontario, the relative evolution of coronary revascularization patterns in both jurisdictions over time is unknown...
Outcome of heart failure with preserved ejection fraction in a population-based studyR Sacha Bhatia
Heart and Stroke/Richard Lewar Centre of Excellence, University of Toronto, and the Division of Cardiology, Toronto General Hospital, University Health Network, Toronto, ON, Canada
N Engl J Med 355:260-9. 2006..The survival of patients with heart failure with preserved ejection fraction was similar to that of patients with reduced ejection fraction...
Recent trends in cardiovascular complications among men and women with and without diabetesGillian L Booth
Department of Medicine, University of Toronto, Ontario, Canada
Diabetes Care 29:32-7. 2006..To compare recent trends in cardiovascular disease (CVD) outcomes among men and women with diabetes with those in the nondiabetic population...
Risk-treatment mismatch in the pharmacotherapy of heart failureDouglas S Lee
Institute for Clinical Evaluative Sciences, Department of Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada
JAMA 294:1240-7. 2005..Understanding the reasons underlying this mismatch may facilitate improvements in care and outcomes for patients with heart failure...
Statin therapy and clinical outcomes in heart failure: a propensity-matched analysisMaral Ouzounian
Heart and Stroke Richard Lewar Centre for Excellence, University of Toronto, Toronto, Ontario, Canada
J Card Fail 15:241-8. 2009..The influence of statin therapy in heart failure (HF) has been of considerable interest. The objective of this study was to determine if statins are associated with improved outcomes in patients discharged after hospitalization for HF...
Quality of care and outcomes of older patients with heart failure hospitalized in the United States and CanadaDennis T Ko
Department of Cardiology, Schulich Heart Centre, Toronto, Ontario
Arch Intern Med 165:2486-92. 2005..3%, P = .98). CONCLUSION: Patients with heart failure who are hospitalized in the United States had lower short-term mortality at 30 days, but 1-year mortality rates were not significantly different between the United States and Canada...
Comparison of coding of heart failure and comorbidities in administrative and clinical data for use in outcomes researchDouglas S Lee
Institute for Clinical Evaluative Sciences, Toronto, Canada
Med Care 43:182-8. 2005..Examination of hospitalization data up to 1 year prior to the index admission improves comorbidity detection and may provide enhancements to future studies of heart failure mortality...
The real-world outcomes of off-pump coronary artery bypass surgery in a public health care systemVeena Guru
Institute for Clinical Evaluative Sciences, Division of Cardiovascular Surgery, University of Toronto, Ontario
Can J Cardiol 23:281-6. 2007..The population-based results of off-pump coronary artery bypass surgery (OPCAB) in a public health care system have not been reported...
Prevalence, predictors, and outcomes of primary nonadherence after acute myocardial infarctionCynthia A Jackevicius
University Health Network and Department of Health Policy, Management, and Evaluation, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Circulation 117:1028-36. 2008..Our objectives were to characterize, to determine factors of, and to measure outcomes associated with primary nonadherence after AMI...
Trends in heart failure outcomes and pharmacotherapy: 1992 to 2000Douglas S Lee
Faculty of Pharmacy, Toronto, Canada
Am J Med 116:581-9. 2004..CONCLUSION: During 1992 to 2000, mortality and morbidity improved among elderly patients with heart failure, with increased utilization of beta-blockers contributing most to the beneficial trends in outcomes...
Health outcomes categorized by current and previous definitions of acute myocardial infarction in an unselected cohort of troponin-naïve emergency department patientsPeter A Kavsak
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada, and Department of Pathology, Women and Infants Hospital of Rhode Island, Providence, USA
Clin Chem 52:2028-35. 2006..The health outcomes were based on the WHO definition and occurred in an era that preceded the use of cardiac troponin biomarkers...
Biology or bias: practice patterns and long-term outcomes for men and women with acute myocardial infarctionD A Alter
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
J Am Coll Cardiol 39:1909-16. 2002..Another objective was to evaluate the association of age, gender and treatment intensity with five-year survival after AMI...
Validity of the GRACE (Global Registry of Acute Coronary Events) acute coronary syndrome prediction model for six month post-discharge death in an independent data setP J Bradshaw
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Heart 92:905-9. 2006....
Problems for clinical judgement: 3. Thinking clearly in an emergencyM J Schull
Division of Emergency Medicine, University of Toronto, Toronto, Ont
CMAJ 164:1170-5. 2001..Better training and teamwork may allow for clearer thinking in emergencies, so that knowledge can be translated into effective action and better patient outcomes...
Publicly reported provider outcomes: the concerns of cardiac surgeons in a single-payer systemVeena Guru
Institute for Clinival Evaluative Sciences, University of Toronto, Toronto, Ontario, Canada
Can J Cardiol 25:33-8. 2009..Provider outcomes reports are an important part of quality improvement efforts. The positive and negative impact of such reports on the delivery of care has not been extensively explored...
Relationship between preventability of death after coronary artery bypass graft surgery and all-cause risk-adjusted mortality ratesVeena Guru
Institute for Clinical Evaluative Sciences, G 106, 2075 Bayview Ave, Toronto, Ontario M4N 3M5 Canada
Circulation 117:2969-76. 2008....
Long-term health outcomes associated with detectable troponin I concentrationsPeter A Kavsak
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada
Clin Chem 53:220-7. 2007..We designed this study to extend this observation by examining risk prediction in both men and women presenting to an emergency department with chest discomfort...
Do operator volumes relate to clinical outcomes after percutaneous coronary intervention in the Canadian health care system?Warren J Cantor
University of Toronto, Toronto, Ontario, Canada
Am Heart J 151:902-8. 2006..No study has assessed whether this relationship exists in Canada, where PCI is performed only at a limited number of regional centers and operator volumes are higher...
Association of temporal trends in risk factors and treatment uptake with coronary heart disease mortality, 1994-2005Harindra C Wijeysundera
Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
JAMA 303:1841-7. 2010..Coronary heart disease (CHD) mortality has declined substantially in Canada since 1994...
Adherence with statin therapy in elderly patients with and without acute coronary syndromesCynthia A Jackevicius
Department of Health Policy, Management, and Evaluation, Pharmacy Department and Women s Health Program, University Health Network Toronto General Hospital, 200 Elizabeth St, Toronto, Ontario, Canada M5G 2C4
JAMA 288:462-7. 2002..Research prior to these trials of older lipid-lowering agents demonstrated low levels of 1-year adherence...
CCORT/CCS quality indicators for acute myocardial infarction careChau T T Tran
Institute for Clinical Evaluative Sciences, Toronto, Ontario
Can J Cardiol 19:38-45. 2003..It is anticipated that these indicators will be useful to clinicians and researchers who want to measure and improve the quality of AMI patient care in Canada...
Regional outcomes of heart failure in CanadaDouglas S Lee
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Can J Cardiol 20:599-607. 2004..The mortality and readmission rates for this condition are high and exhibit variation among health regions and provinces. Factors contributing to regional variations in these outcomes merit further study...
An overview of the methods and data used in the CCORT Canadian Cardiovascular Atlas projectCourtney C Kennedy
Institute for Clinical Evaluative Sciences, Toronto, Canada
Can J Cardiol 19:655-63. 2003....
Developing risk-adjusted 30-day hospital mortality ratesAnn E Tourangeau
Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada
Res Nurs Health 26:483-96. 2003..This procedure is useful for developing risk-adjusted outcomes with administrative data similar to those used in this study...
Use of the statins in patients after acute myocardial infarction: does evidence change practice?C A Jackevicius
Pharmacy Department, University Health Network Toronto General Hospital, 200 Elizabeth St, Toronto, Ontario, Canada M5G 2C4
Arch Intern Med 161:183-8. 2001....
Outpatient antibiotic therapy and short term mortality in elderly patients with chronic obstructive pulmonary diseaseD D Sin
Sunnybrook and Women s College Health Science Centre, University of Toronto, Toronto, Canada
Can Respir J 7:466-71. 2000..To determine the association between outpatient use of oral antibiotics and 30-day all-cause mortality following hospitalization in a group of elderly chronic obstructive pulmonary disease (COPD) patients...
The influence of surgical specialty training on the outcomes of elective abdominal aortic aneurysm surgeryJ V Tu
Institute for Clinical Evaluative Sciences (ICES, the Division of General Internal Medicine and Clinical Epidemiology and Health Care Research Program at Sunnybrook and Women's College Health Science Centre, University of Toronto, Canada
J Vasc Surg 33:447-52. 2001..These results provide evidence that surgical specialty training in vascular procedures leads to better patient outcomes...
Investigating the determinants of decreasing postmyocardial infarction mortality: an analysis of in-hospital data from 1992 and 1997N Daneman
Department of Medicine, University of Toronto, Toronto, Canada
Can J Cardiol 17:771-6. 2001..The increased use of evidence-based pharmacotherapy may be the most significant contributing factor to declining postmyocardial infarction mortality...
Problems for clinical judgement: 1. Eliciting an insightful history of present illnessD A Redelmeier
Department of Medicine, University of Toronto, Toronto, Ont
CMAJ 164:647-51. 2001..These insights might help clinicians avoid mistakes when eliciting a patient's history of present illness...
Stroke care delivery in institutions participating in the Registry of the Canadian Stroke NetworkMoira K Kapral
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Stroke 35:1756-62. 2004..Guidelines and performance indicators have been established for acute stroke care. However, little is known about the process of stroke care delivery in Canada...
The evaluation of a formalized queue management system for coronary angiography waiting listsD A Alter
Institute for Clinical Evaluative Sciences, Toronto, Canada
Can J Cardiol 21:1203-9. 2005..The extent to which formal queue management systems may improve the prioritization and survival of patients in the angiography queue is unknown...
Hypertension guidelines in elderly patients: is anybody listening?Karen Tu
Institute for Clinical Evaluative Services, G106 2075 Bayview Avenue, Toronto, Ontario M4N 3M5, Canada
Am J Med 113:52-8. 2002....
Emergency department triage of acute myocardial infarction patients and the effect on outcomesClare L Atzema
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Ann Emerg Med 53:736-45. 2009....
Missed opportunities in the secondary prevention of myocardial infarction: an assessment of the effects of statin underprescribing on mortalityPeter C Austin
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Am Heart J 151:969-75. 2006..We explored the potential reduction in mortality at the population level that could result from improving statin prescribing among patients least likely to be prescribed a statin after acute myocardial infarction (AMI)...
Association of blood pressure at hospital discharge with mortality in patients diagnosed with heart failureDouglas S Lee
Institute for Clinical Evaluative Sciences, Ontario, Canada
Circ Heart Fail 2:616-23. 2009..Higher blood pressure in acute heart failure has been associated with improved survival; however, the relationship between blood pressure and survival in stabilized patients at hospital discharge has not been established...
One-year outcome of patients after acute coronary syndromes (from the Canadian Acute Coronary Syndromes Registry)Andrew T Yan
Terrence Donnelly Heart Centre, Division of Cardiology, St. Michael's Hospital, University of Toronto, Ontario, Canada
Am J Cardiol 94:25-9. 2004..Moreover, there was a significant opportunity to enhance the discharge and long-term use of evidence-based secondary prevention therapies...
Development and validation of the Osteoporosis Risk Assessment Instrument to facilitate selection of women for bone densitometryS M Cadarette
Canadian Multicentre Osteoporosis Study, University of Toronto, Ont
CMAJ 162:1289-94. 2000..The objective of this study was to develop and validate a clinical tool to help clinicians identify which women are at increased risk for osteoporosis and should therefore undergo further testing with bone densitometry...
Myocardial infarction and the validation of physician billing and hospitalization data using electronic medical recordsK Tu
Institute for Clinical Evaluative Sciences ICES, Toronto, Canada
Chronic Dis Can 30:141-6. 2010..We set out to determine if adding physician billing data to hospital discharge data would result in an accurate capture of patients who have had a myocardial infarction...
Rate of stroke recurrence in patients with primary intracerebral hemorrhageM D Hill
Toronto Western Hospital, University of Toronto, Division of Neurology, Ontario, Canada
Stroke 31:123-7. 2000..We sought to determine the rate of recurrence of ICH or cerebral ischemia in a cohort of PICH patients at the Toronto Hospital, Toronto, Canada...
Inhaled corticosteroid therapy reduces the risk of rehospitalization and all-cause mortality in elderly asthmaticsD D Sin
Institute for Clinical Evaluation Sciences (ICES, Sunnybrook and Women's College Health Science Center, University of Toronto, Ontario, Canada
Eur Respir J 17:380-5. 2001..These findings suggest that inhaled corticosteroids are beneficial in reducing the risk for rehospitalization and all-cause mortality in elderly patients with asthma who have recently been hospitalized for their disease...
Nursing-related determinants of 30-day mortality for hospitalized patientsA E Tourangeau
Faculty of Nursing, University of Toronto, Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Can J Nurs Res 33:71-88. 2002..These findings can be used to predict the effects of hospital changes in nursing skill mix and years of RN experience on patient mortality...
Quality of congestive heart failure treatment at a Canadian teaching hospitalE Weil
Faculty of Medicine, University of Toronto, Toronto, Ont
CMAJ 165:284-7. 2001..INTERPRETATION: Most patients who had CHF at this Canadian hospital received left ventricular function testing and ACE inhibitor therapy. Future educational efforts should focus on the importance of adequate dosing of ACE inhibitors...
Problems for clinical judgement: 4. Surviving in the report card eraJ V Tu
Department of Medicine, University of Toronto, Toronto, Ont
CMAJ 164:1709-12. 2001..We offer a number of tips ranging from knowing your outcomes first to proactively getting involved in developing report cards...
Deriving ethnic-specific BMI cutoff points for assessing diabetes riskMaria Chiu
Institute for Clinical Evaluative Sciences, Ontario, Canada
Diabetes Care 34:1741-8. 2011..We compared the incidence rates of diabetes across white, South Asian, Chinese, and black populations and identified equivalent ethnic-specific BMI cutoff values for assessing diabetes risk...
Comparing invasive and noninvasive management strategies for acute myocardial infarction using administrative databasesLouise Pilote
Division of Clinical Epidemiology, McGill University Health Centre, Montreal, Quebec, Canada
Am Heart J 155:42-8. 2008..The aim of this study was to compare outcomes after acute myocardial infarction between regions with low and high catheterization access...
Cardiovascular outcomes after a change in prescription policy for clopidogrelCynthia A Jackevicius
Western University of Health Sciences, College of Pharmacy, 309 E Second St, Pomona, CA 91766, USA
N Engl J Med 359:1802-10. 2008....
Acute treatment of myocardial infarction in Canada 1999-2002Cynthia A Jackevicius
Pharmacy Department, University Health Network Toronto General Hospital, Toronto, Ontario M5G 2C4
Can J Cardiol 21:145-52. 2005..Therapy for management of acute myocardial infarction (AMI) varies according to patient, prescriber and geographical characteristics...
Pharmacological treatment of congestive heart failure in Canada: a description of care in five provincesJafna L Cox
Department of Medicine, Dalhousie University, Halifax, Canada
Can J Cardiol 21:337-43. 2005..There have been major advances in the treatment of this condition over the past two decades, yet little information is currently available regarding the current status of CHF management in Canada...
Effectiveness of statins for secondary prevention in elderly patients after acute myocardial infarction: an evaluation of class effectZheng Zhou
Department of Epidemiology and Biostatistics, McGill University, , Que
CMAJ 172:1187-94. 2005..INTERPRETATION: Our results suggest that, under current usage, statins are equally effective for secondary prevention in elderly patients after AMI...
Population rates of cardiac catheterization and yield of high-risk coronary artery diseaseMichelle M Graham
Department of Medicine, University of Alberta, Edmonton
CMAJ 173:35-9. 2005..The optimal population rate of cardiac catheterization is unknown. One potential way to determine it would be to examine whether there is a population rate beyond which the yield of high-risk coronary artery disease (CAD) does not rise...
Administrative Data Feedback for Effective Cardiac Treatment: AFFECT, a cluster randomized trialChristine A Beck
Division of Clinical Epidemiology, McGill University Health Centre, Montreal, Quebec, Canada
JAMA 294:309-17. 2005..A need exists for further studies to rigorously evaluate the effectiveness of more intensive report card interventions...
