Lorraine L Lipscombe

Summary

Affiliation: Institute for Clinical Evaluative Sciences
Country: Canada

Publications

  1. ncbi request reprint Reduced screening mammography among women with diabetes
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Arch Intern Med 165:2090-5. 2005
  2. ncbi request reprint Increased prevalence of prior breast cancer in women with newly diagnosed diabetes
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Breast Cancer Res Treat 98:303-9. 2006
  3. ncbi request reprint Diabetes mellitus and breast cancer: a retrospective population-based cohort study
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, M4N 3M5, Toronto, Ontario, Canada
    Breast Cancer Res Treat 98:349-56. 2006
  4. ncbi request reprint Trends in diabetes prevalence, incidence, and mortality in Ontario, Canada 1995-2005: a population-based study
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
    Lancet 369:750-6. 2007
  5. ncbi request reprint The risk of hip fractures in older individuals with diabetes: a population-based study
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Diabetes Care 30:835-41. 2007
  6. ncbi request reprint The growing prevalence of diabetes in Ontario: are we prepared?
    Lorraine L Lipscombe
    Department of Medicine, University of Toronto
    Healthc Q 10:23-5. 2007
  7. ncbi request reprint The impact of diabetes on survival following breast cancer
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
    Breast Cancer Res Treat 109:389-95. 2008
  8. ncbi request reprint Thiazolidinediones and cardiovascular outcomes in older patients with diabetes
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    JAMA 298:2634-43. 2007
  9. doi request reprint Antipsychotic drugs and the risk of hyperglycemia in older adults without diabetes: a population-based observational study
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Am J Geriatr Psychiatry 19:1026-33. 2011
  10. pmc Mortality among patients with hypertension from 1995 to 2005: a population-based study
    Karen Tu
    Institute for Clinical Evaluative Sciences, University of Toronto, Toronto, Ont
    CMAJ 178:1436-40. 2008

Detail Information

Publications33

  1. ncbi request reprint Reduced screening mammography among women with diabetes
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Arch Intern Med 165:2090-5. 2005
    ....
  2. ncbi request reprint Increased prevalence of prior breast cancer in women with newly diagnosed diabetes
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Breast Cancer Res Treat 98:303-9. 2006
    ..Because insulin levels are at their highest prior to the development of diabetes, breast cancer risk may be even greater during the pre-diabetes period...
  3. ncbi request reprint Diabetes mellitus and breast cancer: a retrospective population-based cohort study
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, M4N 3M5, Toronto, Ontario, Canada
    Breast Cancer Res Treat 98:349-56. 2006
    ..The purpose of this study was to compare the incidence of breast cancer in postmenopausal women with and without diabetes...
  4. ncbi request reprint Trends in diabetes prevalence, incidence, and mortality in Ontario, Canada 1995-2005: a population-based study
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
    Lancet 369:750-6. 2007
    ..The prevalence of diabetes has been increasing greatly, but WHO's predicted 39% rise in the global rate of diabetes from 2000 to 2030 might be an underestimate. We aimed to assess diabetes trends in Ontario, Canada...
  5. ncbi request reprint The risk of hip fractures in older individuals with diabetes: a population-based study
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Diabetes Care 30:835-41. 2007
    ..However, they may still be at increased risk for hip fractures. Using population-based Ontario health care data, we compared the risk of hip fractures among men and women with and without diabetes...
  6. ncbi request reprint The growing prevalence of diabetes in Ontario: are we prepared?
    Lorraine L Lipscombe
    Department of Medicine, University of Toronto
    Healthc Q 10:23-5. 2007
  7. ncbi request reprint The impact of diabetes on survival following breast cancer
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
    Breast Cancer Res Treat 109:389-95. 2008
    ..The purpose of this study was to examine the impact of diabetes on survival following breast cancer...
  8. ncbi request reprint Thiazolidinediones and cardiovascular outcomes in older patients with diabetes
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    JAMA 298:2634-43. 2007
    ..However, the association between TZD use and cardiovascular events has not been adequately evaluated on a population level...
  9. doi request reprint Antipsychotic drugs and the risk of hyperglycemia in older adults without diabetes: a population-based observational study
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Am J Geriatr Psychiatry 19:1026-33. 2011
    ..To determine whether current antipsychotic use among older persons without diabetes is associated with a higher risk of hospital visits for hyperglycemia, as previous studies in this population have yielded conflicting results...
  10. pmc Mortality among patients with hypertension from 1995 to 2005: a population-based study
    Karen Tu
    Institute for Clinical Evaluative Sciences, University of Toronto, Toronto, Ont
    CMAJ 178:1436-40. 2008
    ..We have reported that the prevalence of diagnosed hypertension increased by 60% from 1995 to 2005 in Ontario. In the present study, we asked whether this increase is explained by a decrease in the mortality rate...
  11. ncbi request reprint Clinical and demographic characteristics of patients receiving different oral hypoglycemic agents
    Tara Gomes
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Pharmacoepidemiol Drug Saf 18:756-60. 2009
    ....
  12. doi request reprint Association between metformin use and risk of prostate cancer and its grade
    David Margel
    Division of Urology, Department of Surgical Oncology, Princess Margaret Hospital, University Health Network, Toronto, ON, Canada
    J Natl Cancer Inst 105:1123-31. 2013
    ..Recent evidence suggests that it may possess antitumoral properties. The aim of this study was to test the association between metformin use and risk of prostate cancer and its grade among men with diabetes...
  13. pmc Income-related differences in mortality among people with diabetes mellitus
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ont
    CMAJ 182:E1-E17. 2010
    ..Whether all income groups have benefited equally, however, is unclear. We examined the impact of income on mortality trends among people with diabetes...
  14. pmc Adverse cardiovascular events during treatment with pioglitazone and rosiglitazone: population based cohort study
    David N Juurlink
    Division of Clinical Pharmacology and Toxicology, Department of Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, Canada M4N 3M5
    BMJ 339:b2942. 2009
    ..To compare the risk of acute myocardial infarction, heart failure, and death in patients with type 2 diabetes treated with rosiglitazone and pioglitazone...
  15. doi request reprint The impact of income on the incidence of diabetes: a population-based study
    Zoe Lysy
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Diabetes Res Clin Pract 99:372-9. 2013
    ..Low income status is associated with higher diabetes prevalence and higher mortality. The effect of income on diabetes incidence is less well understood...
  16. pmc Preeclampsia as a risk factor for diabetes: a population-based cohort study
    Denice S Feig
    Department of Medicine, University of Toronto, Toronto, Canada
    PLoS Med 10:e1001425. 2013
    ....
  17. pmc The effectiveness and efficiency of diabetes screening in Ontario, Canada: a population-based cohort study
    Sarah E Wilson
    Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue, Toronto, Ontario, Canada
    BMC Public Health 10:506. 2010
    ....
  18. doi request reprint Metformin use and all-cause and prostate cancer-specific mortality among men with diabetes
    David Margel
    Princess Margaret Hospital, University Health, Toronto, Canada
    J Clin Oncol 31:3069-75. 2013
    ..To evaluate the association between cumulative duration of metformin use after prostate cancer (PC) diagnosis and all-cause and PC-specific mortality among patients with diabetes...
  19. pmc Universal drug coverage and socioeconomic disparities in major diabetes outcomes
    Gillian L Booth
    Li Ka Shing Knowledge Institute of St Michael s Hospital, Toronto, Ontario, Canada
    Diabetes Care 35:2257-64. 2012
    ..We examined whether income disparities in diabetes-related morbidity or mortality decline after age 65 in a setting where much of health care is publicly funded yet universal drug coverage starts only at age 65...
  20. doi request reprint Association between tamoxifen treatment and diabetes: a population-based study
    Lorraine L Lipscombe
    Women s College Hospital, Toronto, Canada
    Cancer 118:2615-22. 2012
    ..Tamoxifen may increase diabetes incidence through its estrogen-inhibiting effects. This study assessed whether tamoxifen treatment in older breast cancer survivors is associated with an increased risk of diabetes...
  21. pmc Prevalence and incidence of hypertension from 1995 to 2005: a population-based study
    Karen Tu
    Institute for Clinical Evaluative Sciences, University of Toronto, Toronto, Ont
    CMAJ 178:1429-35. 2008
    ..Thus, accurate estimates of the prevalence of hypertension in a population have important implications for public policy. We sought to assess whether the estimated increase in the prevalence of hypertension has been underestimated...
  22. pmc Levothyroxine dose and risk of fractures in older adults: nested case-control study
    Marci R Turner
    Department of Medicine, University of Toronto, Canada
    BMJ 342:d2238. 2011
    ..To quantify the effect of levothyroxine dose on risk of fractures in older adults...
  23. doi request reprint Near equality in quality for medication utilization among older adults with diabetes with universal medication insurance in Ontario, Canada
    Baiju R Shah
    University of Toronto, Toronto, Ontario, Canada Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    J Eval Clin Pract 20:176-83. 2014
    ....
  24. ncbi request reprint Trends in incidence of diabetes in pregnancy and serious perinatal outcomes: a large, population-based study in Ontario, Canada, 1996-2010
    Denice S Feig
    Department of Medicine, University of Toronto, Toronto, Ontario, CanadaInstitute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, CanadaInstitute for Clinical Evaluative Sciences, Toronto, Ontario, CanadaDepartment of Obstetrics and Gynecology, University of Toronto, Toronto, Ontario, CanadaDivision of Endocrinology and Metabolism, Mount Sinai Hospital, Toronto, Ontario, Canada
    Diabetes Care 37:1590-6. 2014
    ..Women with diabetes in pregnancy have high rates of pregnancy complications. Our aims were to explore trends in the incidence of diabetes in pregnancy and examine whether the risk of serious perinatal outcomes has changed...
  25. pmc Serious events in older Ontario residents receiving bowel preparations for outpatient colonoscopy with various comorbidity profiles: a descriptive, population-based study
    Joanne Man Wai Ho
    University of Toronto, Toronto, Ontario, Canada
    Can J Gastroenterol 26:436-40. 2012
    ..Little is known about adverse events associated with these preparations, particularly in older patients or patients with medical comorbidities...
  26. ncbi request reprint Antipsychotic drugs and hyperglycemia in older patients with diabetes
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Arch Intern Med 169:1282-9. 2009
    ..Evidence suggests that there is an association between antipsychotic drugs and new-onset diabetes, but little is known about the risk of hyperglycemia among persons with preexisting diabetes...
  27. doi request reprint Autoimmune hypothyroidism and breast cancer in the elderly
    Monty K Sandhu
    Department of Medicine, University of Toronto, Toronto, Canada
    Breast Cancer Res Treat 115:635-41. 2009
    ..To determine whether autoimmune hypothyroidism (AIHT) influences breast cancer (BRCA) incidence or all-cause survival...
  28. doi request reprint Pregnancy planning in women with pregestational diabetes
    Lorraine L Lipscombe
    Department of Medicine, Women s College Hospital, Toronto, Ontario, Canada
    J Matern Fetal Neonatal Med 24:1095-101. 2011
    ..We evaluated the adequacy of pregnancy planning effort and medical planning in pregnant women with type 1 and type 2 diabetes...
  29. pmc All-cause mortality and serious cardiovascular events in people with hip and knee osteoarthritis: a population based cohort study
    Gillian A Hawker
    Women s College Research Institute, Women s College Hospital, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    PLoS ONE 9:e91286. 2014
    ..Because individuals with osteoarthritis (OA) avoid physical activities that exacerbate symptoms, potentially increasing risk for cardiovascular disease (CVD) and death, we assessed the relationship between OA disability and these outcomes...
  30. doi request reprint A physician reminder to improve postpartum diabetes screening in women with gestational diabetes mellitus
    Iliana C Lega
    Women s College Hospital, Women s College Research Institute, Toronto, Ontario, Canada
    Diabetes Res Clin Pract 95:352-7. 2012
    ..Guidelines recommend screening for diabetes postpartum, but screening rates are low. We evaluated the effect of a physician reminder on postpartum screening and in women with GDM...
  31. pmc Trends in laboratory testing for diabetes in Ontario, Canada 1995-2005: a population-based study
    Sarah E Wilson
    Institute for Clinical Evaluative Sciences, Ontario, Canada
    BMC Health Serv Res 9:41. 2009
    ..We sought to describe the rates of diabetes-related lab testing in Ontario from 1995-2005, among adults without diabetes, and to explore the extent to which the Canadian clinical practice guidelines for screening are being followed...
  32. doi request reprint Breastfeeding predicts the risk of childhood obesity in a multi-ethnic cohort of women with diabetes
    Denice S Feig
    Department of Medicine, University of Toronto, Ontario, Canada
    J Matern Fetal Neonatal Med 24:511-5. 2011
    ..To determine whether breastfeeding reduced the risk of childhood obesity in the infants of a multi-ethnic cohort of women with pregestational diabetes...
  33. ncbi request reprint Atypical antipsychotics and hyperglycemic emergencies: multicentre, retrospective cohort study of administrative data
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, G1 06, 2075 Bayview Ave, Toronto, ON M4N 3M5, Canada Women s College Hospital, Women s College Research Institute, Department of Medicine, University of Toronto, 790 Bay St, Toronto, ON M5G 1N8, Canada Electronic address
    Schizophr Res 154:54-60. 2014
    ..To evaluate the relationship between initiation of atypical antipsychotic agents and the risk of hyperglycemic emergencies...