Research Topics
| Lorraine L LipscombeSummaryAffiliation: Institute for Clinical Evaluative Sciences Country: Canada Publications
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Detail Information
Publications
Reduced screening mammography among women with diabetesLorraine L Lipscombe
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Arch Intern Med 165:2090-5. 2005....
Increased prevalence of prior breast cancer in women with newly diagnosed diabetesLorraine L Lipscombe
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Breast Cancer Res Treat 98:303-9. 2006..Because insulin levels are at their highest prior to the development of diabetes, breast cancer risk may be even greater during the pre-diabetes period...
Diabetes mellitus and breast cancer: a retrospective population-based cohort studyLorraine L Lipscombe
Institute for Clinical Evaluative Sciences, M4N 3M5, Toronto, Ontario, Canada
Breast Cancer Res Treat 98:349-56. 2006..The purpose of this study was to compare the incidence of breast cancer in postmenopausal women with and without diabetes...
Trends in diabetes prevalence, incidence, and mortality in Ontario, Canada 1995-2005: a population-based studyLorraine L Lipscombe
Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
Lancet 369:750-6. 2007..The prevalence of diabetes has been increasing greatly, but WHO's predicted 39% rise in the global rate of diabetes from 2000 to 2030 might be an underestimate. We aimed to assess diabetes trends in Ontario, Canada...
The risk of hip fractures in older individuals with diabetes: a population-based studyLorraine L Lipscombe
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Diabetes Care 30:835-41. 2007..However, they may still be at increased risk for hip fractures. Using population-based Ontario health care data, we compared the risk of hip fractures among men and women with and without diabetes...
The growing prevalence of diabetes in Ontario: are we prepared?Lorraine L Lipscombe
Department of Medicine, University of Toronto
Healthc Q 10:23-5. 2007
The impact of diabetes on survival following breast cancerLorraine L Lipscombe
Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
Breast Cancer Res Treat 109:389-95. 2008..The purpose of this study was to examine the impact of diabetes on survival following breast cancer...
Thiazolidinediones and cardiovascular outcomes in older patients with diabetesLorraine L Lipscombe
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
JAMA 298:2634-43. 2007..However, the association between TZD use and cardiovascular events has not been adequately evaluated on a population level...
Antipsychotic drugs and the risk of hyperglycemia in older adults without diabetes: a population-based observational studyLorraine L Lipscombe
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Am J Geriatr Psychiatry 19:1026-33. 2011..To determine whether current antipsychotic use among older persons without diabetes is associated with a higher risk of hospital visits for hyperglycemia, as previous studies in this population have yielded conflicting results...
Mortality among patients with hypertension from 1995 to 2005: a population-based studyKaren Tu
Institute for Clinical Evaluative Sciences, University of Toronto, Toronto, Ont
CMAJ 178:1436-40. 2008..We have reported that the prevalence of diagnosed hypertension increased by 60% from 1995 to 2005 in Ontario. In the present study, we asked whether this increase is explained by a decrease in the mortality rate...
Clinical and demographic characteristics of patients receiving different oral hypoglycemic agentsTara Gomes
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Pharmacoepidemiol Drug Saf 18:756-60. 2009....
Income-related differences in mortality among people with diabetes mellitusLorraine L Lipscombe
Institute for Clinical Evaluative Sciences, Toronto, Ont
CMAJ 182:E1-E17. 2010..Whether all income groups have benefited equally, however, is unclear. We examined the impact of income on mortality trends among people with diabetes...
Adverse cardiovascular events during treatment with pioglitazone and rosiglitazone: population based cohort studyDavid N Juurlink
Division of Clinical Pharmacology and Toxicology, Department of Medicine, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, ON, Canada M4N 3M5
BMJ 339:b2942. 2009..To compare the risk of acute myocardial infarction, heart failure, and death in patients with type 2 diabetes treated with rosiglitazone and pioglitazone...
The effectiveness and efficiency of diabetes screening in Ontario, Canada: a population-based cohort studySarah E Wilson
Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue, Toronto, Ontario, Canada
BMC Public Health 10:506. 2010....
Universal drug coverage and socioeconomic disparities in major diabetes outcomesGillian L Booth
Li Ka Shing Knowledge Institute of St Michael s Hospital, Toronto, Ontario, Canada
Diabetes Care 35:2257-64. 2012..We examined whether income disparities in diabetes-related morbidity or mortality decline after age 65 in a setting where much of health care is publicly funded yet universal drug coverage starts only at age 65...
Association between tamoxifen treatment and diabetes: a population-based studyLorraine L Lipscombe
Women s College Hospital, Toronto, Canada
Cancer 118:2615-22. 2012..Tamoxifen may increase diabetes incidence through its estrogen-inhibiting effects. This study assessed whether tamoxifen treatment in older breast cancer survivors is associated with an increased risk of diabetes...
Prevalence and incidence of hypertension from 1995 to 2005: a population-based studyKaren Tu
Institute for Clinical Evaluative Sciences, University of Toronto, Toronto, Ont
CMAJ 178:1429-35. 2008..Thus, accurate estimates of the prevalence of hypertension in a population have important implications for public policy. We sought to assess whether the estimated increase in the prevalence of hypertension has been underestimated...
Levothyroxine dose and risk of fractures in older adults: nested case-control studyMarci R Turner
Department of Medicine, University of Toronto, Canada
BMJ 342:d2238. 2011..To quantify the effect of levothyroxine dose on risk of fractures in older adults...
Serious events in older Ontario residents receiving bowel preparations for outpatient colonoscopy with various comorbidity profiles: a descriptive, population-based studyJoanne Man Wai Ho
University of Toronto, Toronto, Ontario, Canada
Can J Gastroenterol 26:436-40. 2012..Little is known about adverse events associated with these preparations, particularly in older patients or patients with medical comorbidities...
Antipsychotic drugs and hyperglycemia in older patients with diabetesLorraine L Lipscombe
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Arch Intern Med 169:1282-9. 2009..Evidence suggests that there is an association between antipsychotic drugs and new-onset diabetes, but little is known about the risk of hyperglycemia among persons with preexisting diabetes...
Autoimmune hypothyroidism and breast cancer in the elderlyMonty K Sandhu
Department of Medicine, University of Toronto, Toronto, Canada
Breast Cancer Res Treat 115:635-41. 2009..To determine whether autoimmune hypothyroidism (AIHT) influences breast cancer (BRCA) incidence or all-cause survival...
The impact of income on the incidence of diabetes: A population-based studyZoe Lysy
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Diabetes Res Clin Pract 99:372-9. 2013..Low income status is associated with higher diabetes prevalence and higher mortality. The effect of income on diabetes incidence is less well understood...
Pregnancy planning in women with pregestational diabetesLorraine L Lipscombe
Department of Medicine, Women s College Hospital, Toronto, Ontario, Canada
J Matern Fetal Neonatal Med 24:1095-101. 2011..We evaluated the adequacy of pregnancy planning effort and medical planning in pregnant women with type 1 and type 2 diabetes...
A physician reminder to improve postpartum diabetes screening in women with gestational diabetes mellitusIliana C Lega
Women s College Hospital, Women s College Research Institute, Toronto, Ontario, Canada
Diabetes Res Clin Pract 95:352-7. 2012..Guidelines recommend screening for diabetes postpartum, but screening rates are low. We evaluated the effect of a physician reminder on postpartum screening and in women with GDM...
Trends in laboratory testing for diabetes in Ontario, Canada 1995-2005: a population-based studySarah E Wilson
Institute for Clinical Evaluative Sciences, Ontario, Canada
BMC Health Serv Res 9:41. 2009..We sought to describe the rates of diabetes-related lab testing in Ontario from 1995-2005, among adults without diabetes, and to explore the extent to which the Canadian clinical practice guidelines for screening are being followed...
Breastfeeding predicts the risk of childhood obesity in a multi-ethnic cohort of women with diabetesDenice S Feig
Department of Medicine, University of Toronto, Ontario, Canada
J Matern Fetal Neonatal Med 24:511-5. 2011..To determine whether breastfeeding reduced the risk of childhood obesity in the infants of a multi-ethnic cohort of women with pregestational diabetes...
