Research Topics
| Hadas D FischerSummaryAffiliation: Institute for Clinical Evaluative Sciences Country: Canada Publications
| Collaborators
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Detail Information
Publications
Hemorrhage during warfarin therapy associated with cotrimoxazole and other urinary tract anti-infective agents: a population-based studyHadas D Fischer
Department of Health Policy Management and Evaluation, University of Toronto, Toront, Ontario, Canada
Arch Intern Med 170:617-21. 2010..We examined the risk of upper gastrointestinal (UGI) tract hemorrhage in older patients receiving warfarin in combination with antibiotics commonly used to treat urinary tract infection, with a focus on cotrimoxazole...- Older men with dementia are at greater risk than women of serious events after initiating antipsychotic therapyPaula A Rochon
Women s College Research Institute, Women s College Hospital, Toronto, Ontario, Canada Department of Medicine, University of Toronto, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
J Am Geriatr Soc 61:55-61. 2013..To understand how drug therapy differently affects older women and men... - Use of clarithromycin and adverse cardiovascular events among older patients receiving donepezil: a population-based, nested case-control studyJanine R Hutson
Faculty of Medicine, University of Toronto, Toronto, ON, Canada
Drugs Aging 29:205-11. 2012..Donepezil is metabolized by the cytochrome P450 isozyme 3A4 (CYP3A4). Clarithromycin is a potent inhibitor of CYP3A4, and patients taking both of these drugs may be at increased risk of cardiac adverse events... - Antipsychotic drugs and the risk of hyperglycemia in older adults without diabetes: a population-based observational studyLorraine L Lipscombe
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Am J Geriatr Psychiatry 19:1026-33. 2011..To determine whether current antipsychotic use among older persons without diabetes is associated with a higher risk of hospital visits for hyperglycemia, as previous studies in this population have yielded conflicting results... - Current prescription patterns and safety profile of irreversible monoamine oxidase inhibitors: a population-based cohort study of older adultsKenneth I Shulman
Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, M4N 3M5, Canada
J Clin Psychiatry 70:1681-6. 2009..To determine the prescription pattern and safety profile for irreversible monoamine oxidase inhibitors (MAOIs) in older adults over the past decade... - Atypical antipsychotic use and parkinsonism in dementia: effects of drug, dose, and sexConnie Marras
Morton and Gloria Shulman Movement Disorders Centre, Toronto Western Hospital, Toronto, Ontario, Canada
Am J Geriatr Pharmacother 10:381-9. 2012..There is a particular paucity of information on this in real-world use of these drugs, outside of clinical trial settings... - Syncope and its consequences in patients with dementia receiving cholinesterase inhibitors: a population-based cohort studySudeep S Gill
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Arch Intern Med 169:867-73. 2009..These drugs can provoke symptomatic bradycardia and syncope, which may lead to permanent pacemaker insertion. Drug-induced syncope may also precipitate fall-related injuries, including hip fracture... 
Serious events in older Ontario residents receiving bowel preparations for outpatient colonoscopy with various comorbidity profiles: a descriptive, population-based studyJoanne Man Wai Ho
University of Toronto, Toronto, Ontario, Canada
Can J Gastroenterol 26:436-40. 2012..Little is known about adverse events associated with these preparations, particularly in older patients or patients with medical comorbidities...- Management of neuropsychiatric symptoms in long-term care residents with Parkinson's disease: a retrospective cohort studyNathan Herrmann
Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada
Drugs Aging 30:19-22. 2013.... - Antibiotic use in long-term care facilitiesNick Daneman
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
J Antimicrob Chemother 66:2856-63. 2011..Our goal was to examine the prevalence of antibiotic use among long-term care facility residents and the extent of variability across these institutions... - Potential savings of harmonising hospital and community formularies for chronic disease medications initiated in hospitalLauren Lapointe-Shaw
Department of Medicine, University of Toronto, Toronto, Ontario
PLoS ONE 7:e39737. 2012..We sought to determine how much public money could be saved on chronic medications if hospitals promoted the initiation of agents with the lowest outpatient formulary prices... - Association between tamoxifen treatment and diabetes: a population-based studyLorraine L Lipscombe
Women s College Hospital, Toronto, Canada
Cancer 118:2615-22. 2012..Tamoxifen may increase diabetes incidence through its estrogen-inhibiting effects. This study assessed whether tamoxifen treatment in older breast cancer survivors is associated with an increased risk of diabetes... - Unplanned readmissions after hospital discharge among patients identified as being at high risk for readmission using a validated predictive algorithmAndrea Gruneir
Women s College Research Institute, University of Toronto, Canada
Open Med 5:e104-11. 2011..The purpose of this study was to describe medical patients identified using a recently published and validated algorithm (the LACE index) as being at high risk for readmission and to examine their actual hospital readmission rates... - Levothyroxine dose and risk of fractures in older adults: nested case-control studyMarci R Turner
Department of Medicine, University of Toronto, Canada
BMJ 342:d2238. 2011..To quantify the effect of levothyroxine dose on risk of fractures in older adults... - Antipsychotic drugs and hyperglycemia in older patients with diabetesLorraine L Lipscombe
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
Arch Intern Med 169:1282-9. 2009..Evidence suggests that there is an association between antipsychotic drugs and new-onset diabetes, but little is known about the risk of hyperglycemia among persons with preexisting diabetes...