Craig Earle

Summary

Affiliation: Institute for Clinical Evaluative Sciences
Country: Canada

Publications

  1. pmc Aggressiveness of cancer care near the end of life: is it a quality-of-care issue?
    Craig C Earle
    Division of Population Sciences, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    J Clin Oncol 26:3860-6. 2008
  2. doi request reprint Role of comparative effectiveness research in cancer funding decisions in Ontario, Canada
    Jeffrey S Hoch
    Cancer Care Ontario and St Michael s Hospital, Ontario, Canada
    J Clin Oncol 30:4262-6. 2012
  3. doi request reprint Cancer survivorship care: don't let the perfect be the enemy of the good
    Craig C Earle
    Ontario Institute for Cancer Research, Toronto, Ontario, Canada
    J Clin Oncol 30:3764-8. 2012
  4. pmc Variation in use of surveillance colonoscopy among colorectal cancer survivors in the United States
    Talya Salz
    Health Outcomes Research Group, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 307 E, 63rd St, New York, NY 10065, USA
    BMC Health Serv Res 10:256. 2010
  5. pmc Trends in healthcare utilization among older Americans with colorectal cancer: a retrospective database analysis
    Kathleen Lang
    Boston Health Economics, Inc, Waltham, MA, USA
    BMC Health Serv Res 9:227. 2009
  6. pmc Factors associated with improved survival among older colorectal cancer patients in the US: a population-based analysis
    Kathleen Lang
    Boston Health Economics, Inc, Waltham, USA
    BMC Cancer 9:227. 2009
  7. pmc Employment among survivors of lung cancer and colorectal cancer
    Craig C Earle
    Institute for Clinical Evaluative Sciences and University of Toronto, Toronto, Ontario, Canada
    J Clin Oncol 28:1700-5. 2010
  8. pmc The effect on survival of continuing chemotherapy to near death
    Akiko M Saito
    Health Services Research Program, Cancer Care Ontario and the Ontario Institute for Cancer Research, Toronto, ON, Canada
    BMC Palliat Care 10:14. 2011
  9. doi request reprint Effect of lymph node retrieval rates on the utilization of adjuvant chemotherapy in stage II colon cancer
    C C Earle
    Dana Farber Cancer Institute, Boston, Massachusetts, USA
    J Surg Oncol 100:525-8. 2009
  10. doi request reprint Modeling the longitudinal transitions of performance status in cancer outpatients: time to discuss palliative care
    Rinku Sutradhar
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    J Pain Symptom Manage 45:726-34. 2013

Collaborators

Detail Information

Publications88

  1. pmc Aggressiveness of cancer care near the end of life: is it a quality-of-care issue?
    Craig C Earle
    Division of Population Sciences, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    J Clin Oncol 26:3860-6. 2008
    ..Whether the concept of overly aggressive treatment represents a quality-of-care issue that is acceptable to all involved stakeholders is an open question...
  2. doi request reprint Role of comparative effectiveness research in cancer funding decisions in Ontario, Canada
    Jeffrey S Hoch
    Cancer Care Ontario and St Michael s Hospital, Ontario, Canada
    J Clin Oncol 30:4262-6. 2012
    ..Many of the issues faced by Ontario are relevant beyond Canada, including in the United States during this period of health care reform...
  3. doi request reprint Cancer survivorship care: don't let the perfect be the enemy of the good
    Craig C Earle
    Ontario Institute for Cancer Research, Toronto, Ontario, Canada
    J Clin Oncol 30:3764-8. 2012
    ..In this article, we review some of the challenges to providing survivorship care and discuss efforts to prioritize the most essential elements...
  4. pmc Variation in use of surveillance colonoscopy among colorectal cancer survivors in the United States
    Talya Salz
    Health Outcomes Research Group, Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 307 E, 63rd St, New York, NY 10065, USA
    BMC Health Serv Res 10:256. 2010
    ..Using data from a large, multi-regional, population-based cohort, we describe the rate of surveillance colonoscopy and its association with geographic, sociodemographic, clinical, and health services characteristics...
  5. pmc Trends in healthcare utilization among older Americans with colorectal cancer: a retrospective database analysis
    Kathleen Lang
    Boston Health Economics, Inc, Waltham, MA, USA
    BMC Health Serv Res 9:227. 2009
    ..This retrospective cohort study evaluated healthcare resource use among US Medicare beneficiaries diagnosed with CRC between 1992 and 2002...
  6. pmc Factors associated with improved survival among older colorectal cancer patients in the US: a population-based analysis
    Kathleen Lang
    Boston Health Economics, Inc, Waltham, USA
    BMC Cancer 9:227. 2009
    ..The purpose of this study was to estimate the relative impact of changes in demographics, stage at detection, treatment mix, and medical technology on 5-year survival among older colorectal cancer (CRC) patients...
  7. pmc Employment among survivors of lung cancer and colorectal cancer
    Craig C Earle
    Institute for Clinical Evaluative Sciences and University of Toronto, Toronto, Ontario, Canada
    J Clin Oncol 28:1700-5. 2010
    ..To identify the frequency of and factors associated with changes in employment among cancer survivors...
  8. pmc The effect on survival of continuing chemotherapy to near death
    Akiko M Saito
    Health Services Research Program, Cancer Care Ontario and the Ontario Institute for Cancer Research, Toronto, ON, Canada
    BMC Palliat Care 10:14. 2011
    ..abstract:..
  9. doi request reprint Effect of lymph node retrieval rates on the utilization of adjuvant chemotherapy in stage II colon cancer
    C C Earle
    Dana Farber Cancer Institute, Boston, Massachusetts, USA
    J Surg Oncol 100:525-8. 2009
    ..Failing to meet the benchmark of 12 lymph nodes in resection specimens is an indication for adjuvant chemotherapy in stage II colon cancer...
  10. doi request reprint Modeling the longitudinal transitions of performance status in cancer outpatients: time to discuss palliative care
    Rinku Sutradhar
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    J Pain Symptom Manage 45:726-34. 2013
    ..Understanding the longitudinal transitions of performance status among persons with cancer can assist providers in determining the appropriate time to initiate palliative care support...
  11. doi request reprint Symptom clusters in a population-based ambulatory cancer cohort validated using bootstrap methods
    Doris Howell
    Ontario Cancer Institute and Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada
    Eur J Cancer 48:3073-81. 2012
    ..The purpose of this study was to identify and validate common symptom clusters in a large population-based cohort of ambulatory cancer subjects...
  12. doi request reprint Trajectory of performance status and symptom scores for patients with cancer during the last six months of life
    Hsien Seow
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    J Clin Oncol 29:1151-8. 2011
    ..This article describes the trajectory of ESAS and PPS scores 6 months before death...
  13. doi request reprint Do patient-reported symptoms predict emergency department visits in cancer patients? A population-based analysis
    Lisa Barbera
    Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada
    Ann Emerg Med 61:427-437.e5. 2013
    ..The purpose of this study is to determine the relationship between individual patient symptoms and symptom severity, with the likelihood of an emergency department (ED) visit...
  14. doi request reprint The association of the palliative performance scale and hazard of death in an ambulatory cancer population
    Hsien Seow
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    J Palliat Med 16:156-62. 2013
    ..However, little research has examined the association of the PPS with hazard of death in ambulatory populations...
  15. doi request reprint Opioid prescription after pain assessment: a population-based cohort of elderly patients with cancer
    Lisa Barbera
    University of Toronto, Toronto, Ontario, Canada
    J Clin Oncol 30:1095-9. 2012
    ..The purpose of this study was to measure opioid prescription (OP) rates in elderly cancer outpatients around the time of assessment for pain and to evaluate factors associated with receiving OPs for those with severe pain...
  16. doi request reprint Association of area sociodemographic characteristics and capacity for treatment with disparities in colorectal cancer care and mortality
    Jennifer S Haas
    Division of General Medicine and Primary Care, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    Cancer 117:4267-76. 2011
    ..Disparities in treatment and mortality for colorectal cancer (CRC) may reflect differences in access to specialized care or other characteristics of the area where an individual lives...
  17. doi request reprint Costs of first-line doublet chemotherapy and lifetime medical care in advanced non-small-cell lung cancer in the United States
    Kathleen Lang
    i3 Innovus, Medford, MA, USA
    Value Health 12:481-8. 2009
    ....
  18. doi request reprint Surveillance after resection for colorectal cancer
    Phyllis Brawarsky
    Division of General Medicine and Primary Care, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02120 1613, USA
    Cancer 119:1235-42. 2013
    ..This study describes the use of surveillance over time, with a particular focus on racial/ethnic disparities, and also examines the role of area characteristics, such as capacity for CRC screening, on surveillance...
  19. pmc A Protocol for the secure linking of registries for HPV surveillance
    Khaled El Emam
    Electronic Health Information Laboratory, Children s Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada
    PLoS ONE 7:e39915. 2012
    ..The objective of this study was to develop a secure protocol for linking data from different registries and to allow on-going monitoring of HPV vaccine effectiveness...
  20. pmc Secure surveillance of antimicrobial resistant organism colonization or infection in ontario long term care homes
    Khaled El Emam
    Electronic Health Information Laboratory, Children s Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada Paediatrics, University of Ottawa, Ottawa, Ontario, Canada
    PLoS ONE 9:e93285. 2014
    ....
  21. pmc A secure distributed logistic regression protocol for the detection of rare adverse drug events
    Khaled El Emam
    CHEO Research Institute, Ottawa, Ontario, Canada
    J Am Med Inform Assoc 20:453-61. 2013
    ..Existing protocols for addressing these concerns can result in reduced analysis accuracy and can allow sensitive information to leak...
  22. ncbi request reprint End-of-life care for older cancer patients in the Veterans Health Administration versus the private sector
    Nancy L Keating
    The Division of General Internal Medicine, Brigham and Women s Hospital, Department of Health Care Policy, Harvard Medical School, Boston, Massachusetts 02115, USA
    Cancer 116:3732-9. 2010
    ..We compared aggressiveness of end-of-life care of older metastatic cancer patients treated in the Veterans Health Administration (VHA) and those under fee-for-service Medicare arrangements...
  23. doi request reprint Canadian Cancer Risk Management Model: evaluation of cancer control
    William K Evans
    Juravinski Cancer Centre at Hamilton Health Sciences and Department of Oncology, McMaster University, Hamilton, Ontario, Canada
    Int J Technol Assess Health Care 29:131-9. 2013
    ..The aim of this study was to develop a decision support tool to assess the potential benefits and costs of new healthcare interventions...
  24. doi request reprint Income and outcome in myelodysplastic syndrome: the prognostic impact of SES in a single-payer system
    James T England
    MDS Research Program, Medical Oncology Hematology, Sunnybrook Odette Cancer Centre, 2075 Bayview Avenue, Toronto, ON M4N 3M5, Canada
    Leuk Res 37:1495-501. 2013
    ..lowest; p=0.0032). The previously demonstrated association of low SES with poor outcome MDS in the United States may have been driven primarily by reduced access to care rather than other SES-linked factors such as co-morbidity. ..
  25. ncbi request reprint Impact of referral patterns on the use of chemotherapy for lung cancer
    Craig C Earle
    Center for Outcomes and Policy Research, Dana Farber Cancer Center, Boston, MA 02115, USA
    J Clin Oncol 20:1786-92. 2002
    ..To determine the extent to which unexplained variation in the use of chemotherapy for advanced lung cancer is due to access to oncologists' services as opposed to treatment decisions made after seeing an oncologist...
  26. pmc Racial and ethnic differences in end-of-life care in fee-for-service Medicare beneficiaries with advanced cancer
    Alexander K Smith
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    J Am Geriatr Soc 57:153-8. 2009
    ..To examine racial and ethnic variation in use of hospice and high-intensity care in patients with terminal illness...
  27. doi request reprint Symptom burden and performance status in a population-based cohort of ambulatory cancer patients
    Lisa Barbera
    Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada
    Cancer 116:5767-76. 2010
    ..In a broad cross-section of cancer outpatients, the authors describe the ESAS and PPS scores and their relation to patient characteristics...
  28. pmc Association of local capacity for endoscopy with individual use of colorectal cancer screening and stage at diagnosis
    Jennifer S Haas
    Division of General Medicine and Primary Care, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA, USA
    Cancer 116:2922-31. 2010
    ..Limited capacity for endoscopy in areas in which African Americans and Hispanics live may be a reason for persistent disparities in colorectal cancer (CRC) screening and stage at diagnosis...
  29. doi request reprint Etiology of delays in the initiation of adjuvant chemotherapy and their impact on outcomes for Stage II and III rectal cancer
    Winson Y Cheung
    Department of Medical Oncology, University of Toronto, Toronto, Ontario, Canada
    Dis Colon Rectum 52:1054-63; discussion 1064. 2009
    ..This study was designed to evaluate the role of access to care and postsurgical recovery on delays in adjuvant chemotherapy for rectal cancer...
  30. ncbi request reprint Failing to plan is planning to fail: improving the quality of care with survivorship care plans
    Craig C Earle
    Division of Population Sciences, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 24:5112-6. 2006
    ..This article reviews the elements of the proposed survivorship care plan and discusses areas of research and development needed to make them part of standard oncology practice...
  31. ncbi request reprint Under use of necessary care among cancer survivors
    Craig C Earle
    Division of Population Sciences, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Cancer 101:1712-9. 2004
    ..Special attention and education are needed to ensure that survivors receive optimal medical services...
  32. ncbi request reprint Trends in the aggressiveness of cancer care near the end of life
    Craig C Earle
    MSc, Center for Outcomes and Policy Research, Dana Farber Cancer Center, 44 Binney St, 454 STE 21 24, Boston, MA 02115, USA
    J Clin Oncol 22:315-21. 2004
    ..To characterize the aggressiveness of end-of-life cancer treatment for older adults on Medicare, and its relationship to the availability of healthcare resources...
  33. ncbi request reprint Evaluating claims-based indicators of the intensity of end-of-life cancer care
    Craig C Earle
    Division of Population Sciences, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Int J Qual Health Care 17:505-9. 2005
    ..To evaluate measures that could use existing administrative data to assess the intensity of end-of-life cancer care...
  34. ncbi request reprint The effect of race on invasive staging and surgery in non-small-cell lung cancer
    Christopher S Lathan
    Division of Population Sciences, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 24:413-8. 2006
    ..To isolate the effect of decision making from access to care, we used receipt of surgical staging as a proxy for access and willingness to undergo invasive procedures, and examined treatments and outcomes by race...
  35. pmc Influence of socioeconomic status on survival of hepatocellular carcinoma in the Ontario population; a population-based study, 1990-2009
    Nathaniel Jembere
    Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
    PLoS ONE 7:e40917. 2012
    ..We aimed to assess if an association between SES and HCC survival existed in the Canadian context...
  36. pmc A secure protocol for protecting the identity of providers when disclosing data for disease surveillance
    Khaled El Emam
    Children s Hospital of Eastern Ontario Research Institute, Ottawa, Ontario, Canada
    J Am Med Inform Assoc 18:212-7. 2011
    ..Providers have been reluctant to disclose patient data for public-health purposes. Even if patient privacy is ensured, the desire to protect provider confidentiality has been an important driver of this reluctance...
  37. pmc When is cancer care cost-effective? A systematic overview of cost-utility analyses in oncology
    Dan Greenberg
    Evaluation of Value and Risk in Health, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA 02111, USA
    J Natl Cancer Inst 102:82-8. 2010
    ..Because we found only modest improvement in the quality of studies, we suggest that journals provide specific guidance for reporting CUA and assure that authors adhere to guidelines for conducting and reporting economic evaluations...
  38. doi request reprint Trends and predictors of first-line chemotherapy use among elderly patients with advanced non-small cell lung cancer in the United States
    Kathleen Lang
    i3 Innovus, Medford, MA, USA
    Lung Cancer 63:264-70. 2009
    ....
  39. pmc Racial composition of hospitals: effects on surgery for early-stage non-small-cell lung cancer
    Christopher S Lathan
    Department of Medical Oncology, Division of Population Sciences, Center for Outcomes and Policy Research, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 26:4347-52. 2008
    ..Our study examines the relationship between the percentage of black patients treated at a hospital to determine whether it affects the likelihood of obtaining cancer-directed surgery for patients with non-small-cell lung cancer (NSCLC)...
  40. pmc Physician factors associated with discussions about end-of-life care
    Nancy L Keating
    Division of General Internal Medicine, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Cancer 116:998-1006. 2010
    ..Guidelines recommend advanced care planning for terminally ill patients with <1 year to live. Few data are available regarding when physicians and their terminally ill patients typically discuss end-of-life issues...
  41. pmc Comparison of prospective and retrospective indicators of the quality of end-of-life cancer care
    Soko Setoguchi
    Division of General Medicine and Primary Care, Brigham and Women s Hospital, Boston, MA 02120 1613, USA
    J Clin Oncol 26:5671-8. 2008
    ..To compare prospectively and retrospectively defined benchmarks for the quality of end-of-life care, including a novel indicator for the use of opiate analgesia...
  42. doi request reprint Comparisons of patient and physician expectations for cancer survivorship care
    Winson Y Cheung
    Harvard School of Public Health, Center for Outcomes and Policy Research, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    J Clin Oncol 27:2489-95. 2009
    ..To compare expectations for cancer survivorship care between patients and their physicians and between primary care providers (PCPs) and oncologists...
  43. pmc The interface between primary and oncology specialty care: treatment through survivorship
    Eva Grunfeld
    Institute for Clinical Evaluative Sciences, 2075 Bayview Ave, G Wing Rm 106, Toronto, ON, Canada
    J Natl Cancer Inst Monogr 2010:25-30. 2010
    ..Research questions that remain to be answered with respect to survivorship care plans and other aspects of survivorship care are discussed...
  44. pmc Health care costs in the last week of life: associations with end-of-life conversations
    Baohui Zhang
    Center for Psycho Oncology and Palliative Care Research, Boston, MA 02115, USA
    Arch Intern Med 169:480-8. 2009
    ..Life-sustaining medical care of patients with advanced cancer at the end of life (EOL) is costly. Patient-physician discussions about EOL wishes are associated with lower rates of intensive interventions...
  45. pmc Lower use of hospice by cancer patients who live in minority versus white areas
    Jennifer S Haas
    Division of General Medicine and Primary Care, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120 1613, USA
    J Gen Intern Med 22:396-9. 2007
    ..Although hospice care can alleviate suffering at the end of life for patients with cancer, it remains underutilized, particularly by African Americans and Hispanics...
  46. pmc Racial segregation and disparities in cancer stage for seniors
    Jennifer S Haas
    Division of General Medicine and Primary Care, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    J Gen Intern Med 23:699-705. 2008
    ..Disparities in cancer survival may be related to differences in stage. Segregation may be associated with disparities in stage, particularly for cancers for which screening promotes survival...
  47. ncbi request reprint Radiation therapy after mastectomy between 1991 and 1999 in elderly women: response to clinical trial information
    Rinaa S Punglia
    Department of Radiation Oncology and Center for Outcomes and Policy Research, Division of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 24:3474-82. 2006
    ..We sought to study the receipt of PMRT in elderly women in this period, using a population-based cohort of women with breast cancer...
  48. ncbi request reprint Influenza vaccination in elderly patients with advanced colorectal cancer
    Craig C Earle
    Department of Adult Oncology, Dana Farber Cancer Institute, and Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02115, USA
    J Clin Oncol 21:1161-6. 2003
    ..To examine influenza vaccination use in patients undergoing chemotherapy for advanced cancer...
  49. ncbi request reprint Identifying potential indicators of the quality of end-of-life cancer care from administrative data
    Craig C Earle
    Division of Population Sciences Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 21:1133-8. 2003
    ..To explore potential indicators of the quality of end-of-life services for cancer patients that could be monitored using existing administrative data...
  50. doi request reprint Ten-year survival and cost following breast cancer recurrence: estimates from SEER-medicare data
    Michael E Stokes
    i3 Innovus, Medford, MA, USA
    Value Health 11:213-20. 2008
    ..Assessing the value of these treatments is compromised by a paucity of data on the impact of recurrence on economic costs and survival. The purpose of this study was to shed light on these issues...
  51. doi request reprint Long term care planning for cancer survivors: a health services research agenda
    Craig C Earle
    Center for Outcomes and Policy Research, Dana Farber Cancer Center, 44 Binney St, SM 271, Boston, MA 02115, USA
    J Cancer Surviv 1:64-74. 2007
    ..The IOM stated that survivorship care plans 'have strong face validity and can reasonably be assumed to improve care unless and until evidence accumulates to the contrary.'..
  52. ncbi request reprint Phase I study of gefitinib plus FOLFIRI in previously untreated patients with metastatic colorectal cancer
    Brian M Wolpin
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Clin Colorectal Cancer 6:208-13. 2006
    ....
  53. pmc Trends in the aggressiveness of end-of-life cancer care in the universal health care system of Ontario, Canada
    Thi H Ho
    Ontario Institute for Cancer Research, Toronto, Ontario, Canada
    J Clin Oncol 29:1587-91. 2011
    ..To describe trends in the aggressiveness of end-of-life (EOL) cancer care in a universal health care system in Ontario, Canada, between 1993 and 2004, and to compare with findings reported in the United States...
  54. doi request reprint Progress for resectable pancreatic [corrected] cancer?: a population-based assessment of US practices
    Jessica P Simons
    Department of Surgery, Surgical Outcomes Analysis and Research, University of Massachusetts Medical School, Worcester, Massachusetts, USA
    Cancer 116:1681-90. 2010
    ..Progress was evaluated at a national level in resected patients, as measured by the proportion who received guideline-directed treatment and trends in survival...
  55. ncbi request reprint Effect of distance to radiation treatment facility on use of radiation therapy after mastectomy in elderly women
    Rinaa S Punglia
    Department of Radiation Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    Int J Radiat Oncol Biol Phys 66:56-63. 2006
    ..We sought to study the effect of distance to the nearest radiation treatment facility on the use of postmastectomy radiation therapy (PMRT) in elderly women...
  56. ncbi request reprint Efficacy of cetuximab after treatment with oral epidermal growth factor receptor tyrosine kinase inhibitor-based chemotherapy in metastatic colorectal cancer
    Jeffrey A Meyerhardt
    Dana Farber Cancer Institute, Brigham Women s Hospital, Boston, MA 02115, USA
    Clin Colorectal Cancer 6:59-65. 2006
    ..Whether these results apply to other cancer types is unknown but worthy of further study...
  57. ncbi request reprint Phase II study of capecitabine, oxaliplatin, and erlotinib in previously treated patients with metastastic colorectal cancer
    Jeffrey A Meyerhardt
    Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Clin Oncol 24:1892-7. 2006
    ..To investigate the combination of erlotinib, capecitabine, and oxaliplatin in patients who were previously treated for metastatic colorectal cancer...
  58. ncbi request reprint Effect of surgeon specialty on processes of care and outcomes for ovarian cancer patients
    Craig C Earle
    Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
    J Natl Cancer Inst 98:172-80. 2006
    ..e., better outcomes). We examined associations between physician specialty and outcomes in a population-based cohort of elderly ovarian cancer surgery patients...
  59. ncbi request reprint Treatment patterns, outcomes and costs among elderly patients with chronic myeloid leukaemia: a population-based analysis
    Joseph Menzin
    Boston Health Economics, Inc, Waltham, Massachusetts, USA
    Drugs Aging 21:737-46. 2004
    ..To fill this void, our study uses population-based data to evaluate longer-term treatment patterns, outcomes and costs among elderly Medicare beneficiaries following their diagnosis of CML...
  60. ncbi request reprint A phase II study of modified deGramont 5-fluorouracil, leucovorin, and oxaliplatin in previously treated patients with metastatic colorectal cancer
    David P Ryan
    Dana Farber Partners Cancer Care Gastrointestinal Cancer Center, Brigham and Women s Hospital, Dana Farber Cancer Institute, Massachusetts General Hospital, Boston, Massachusetts, USA
    Cancer Invest 21:505-11. 2003
    ....
  61. pmc Follow-up of patients with curatively resected colorectal cancer: a practice guideline
    Alvaro Figueredo
    Hamilton Regional Cancer Centre McMaster University, Hamilton, Ontario, Canada
    BMC Cancer 3:26. 2003
    ..A systematic review was conducted to evaluate the literature regarding the impact of follow-up on colorectal cancer patient survival and, in a second phase, recommendations were developed...
  62. ncbi request reprint Treatment of locally advanced pancreatic cancer in the real world: population-based practices and effectiveness
    Monika K Krzyzanowska
    Center for Outcomes and Policy Research, Dana Farber Cancer Institute, 44 Binney St, 454 STE 21 24, Boston, MA 02115, USA
    J Clin Oncol 21:3409-14. 2003
    ..To evaluate the use and effectiveness of cancer-directed therapy in elderly patients with locally advanced pancreatic cancer (LAPC)...
  63. ncbi request reprint Identifying cancer relapse using SEER-Medicare data
    Craig C Earle
    Department of Adult Oncology, Dana Farber Cancer Institute, Boston, Massachusetts 02115, USA
    Med Care 40:IV-75-81. 2002
    ..Linking administrative data to registry data, as in the creation of the SEER (Surveillance, Epidemiology, and End Results) and Medicare data set, can provide the ability to infer the occurrence of relapse in selected situations...
  64. ncbi request reprint Frequency and cost of chemotherapy-related serious adverse effects in a population sample of women with breast cancer
    Michael J Hassett
    Center for Outcomes and Policy Research, Dana Farber Cancer Institute, 44 Binney Street, 454 STE 21, Boston, MA 02115 6084, USA
    J Natl Cancer Inst 98:1108-17. 2006
    ..The number, nature, and costs of serious adverse effects experienced by younger women receiving chemotherapy for breast cancer outside of clinical trials are unknown...
  65. doi request reprint Racial differences in cancer specialist consultation, treatment, and outcomes for locoregional pancreatic adenocarcinoma
    Melissa M Murphy
    Department of Surgery, Surgical Outcomes Analysis and Research, University of Massachusetts Medical School, Worcester, MA, USA
    Ann Surg Oncol 16:2968-77. 2009
    ..Blacks have a higher incidence of pancreatic adenocarcinoma and worse outcomes compared to whites. Identifying barriers in pancreatic cancer care may explain survival differences and provide areas for intervention...
  66. doi request reprint Mental health service utilization among long-term cancer survivors
    Craig C Earle
    Division of Population Sciences, Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA, USA
    J Cancer Surviv 1:156-60. 2007
    ..Although generally well-adjusted, a subset of cancer survivors have been observed to experience ongoing psychological distress. There has been little study of mental health care utilization among cancer survivors, however...
  67. pmc Discussions with physicians about hospice among patients with metastatic lung cancer
    Haiden A Huskamp
    Department of Health Care Policy, Harvard Medical School, 180 Longwood Ave, Boston, MA 02115, USA
    Arch Intern Med 169:954-62. 2009
    ..Many terminally ill patients enroll in hospice only in the final days before death or not at all. Discussing hospice with a health care provider could increase awareness of hospice and possibly result in earlier use...
  68. pmc Outcomes for lymphoid malignancies in the Nurses' Health Study (NHS) as compared to the Surveillance, Epidemiology and End Results (SEER) Program
    Gregory A Abel
    Center for Outcomes and Policy Research, Department of Medical Oncology, Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA
    Hematol Oncol 28:133-6. 2010
    ..26 [1.07, 1.48]). Our analysis suggests that, at least among white women, SEER is a reliable data source with respect to lymphoid malignancies...
  69. ncbi request reprint Phase I study of gefitinib, irinotecan, 5-fluorouracil and leucovorin in patients with metastatic colorectal cancer
    Jeffrey A Meyerhardt
    Dana Farber Cancer Institute, Boston, MA 02115, USA
    Cancer Chemother Pharmacol 60:661-70. 2007
    ....
  70. pmc Racial segregation and disparities in breast cancer care and mortality
    Jennifer S Haas
    Division of General Medicine and Primary Care, Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts 02120 1613, USA
    Cancer 113:2166-72. 2008
    ..Questions have existed as to whether residential segregation is a mediator of racial/ethnic disparities in breast cancer care and breast cancer mortality, or has a differential effect by race/ethnicity...
  71. ncbi request reprint Patient and treatment factors associated with complications after prostate brachytherapy
    Aileen B Chen
    Harvard Radiation Oncology Program, Dana Farber Cancer Institute, Brigham and Women s Hospital, Boston, MA 02115, USA
    J Clin Oncol 24:5298-304. 2006
    ..To assess the prevalence and predictors of complications after prostate brachytherapy in a population-based sample of older men...
  72. doi request reprint Associations among cancer survivorship discussions, patient and physician expectations, and receipt of follow-up care
    Winson Y Cheung
    British Columbia Cancer Agency, Vancouver, British Columbia, Canada
    J Clin Oncol 28:2577-83. 2010
    ..To explore the associations among cancer survivorship discussions, patient-physician expectations, and receipt of follow-up care in cancer survivors...
  73. ncbi request reprint Do unto others
    Craig C Earle
    J Clin Oncol 24:3331-2. 2006
  74. ncbi request reprint Measuring complications of cancer treatment using the SEER-Medicare data
    Arnold L Potosky
    Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland 20892 7344, USA
    Med Care 40:IV-62-8. 2002
    ..One category of outcomes amenable to research using Medicare claims is complications of cancer treatments: the unintentional, adverse side effects or sequelae of interventions used to treat or palliate cancer patients...
  75. doi request reprint Preventive care for colorectal cancer survivors: a 5-year longitudinal study
    Claire F Snyder
    Division of General Internal Medicine, Johns Hopkins School of Medicine, 624 N Broadway, Room 657, Baltimore, MD 21205, USA
    J Clin Oncol 26:1073-9. 2008
    ..To explore the mix of physician specialties that long-term survivors visit and how the mix relates to preventive care...
  76. ncbi request reprint Quality of non-breast cancer health maintenance among elderly breast cancer survivors
    Craig C Earle
    Center for Outcomes and Policy Research, Dana Farber Cancer Center, 44 Binney St, Boston 02115, USA
    J Clin Oncol 21:1447-51. 2003
    ..To assess the quality of preventive health care, the role of health care participation, and the patient and provider characteristics associated with high-quality care for breast cancer survivors...
  77. pmc Toward population-based indicators of quality end-of-life care: testing stakeholder agreement
    Eva Grunfeld
    Cancer Outcomes Research Program, Cancer Care Nova Scotia, Halifax, Nova Scotia
    Cancer 112:2301-8. 2008
    ..The objective of this study was to assess stakeholder acceptability of QIs of end-of-life (EOL) care that potentially were measurable from population-based administrative health databases...
  78. ncbi request reprint Methodological issues in the use of administrative claims data to study surveillance after cancer treatment
    Ann Butler Nattinger
    Department of Medicine, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Med Care 40:IV-69-74. 2002
    ..Administrative claims databases linked to tumor registry data provide an excellent opportunity for studying the follow-up care of cancer patients...
  79. pmc Trends in follow-up and preventive care for colorectal cancer survivors
    Claire F Snyder
    Division of General Internal Medicine, Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    J Gen Intern Med 23:254-9. 2008
    ..As cancer patients transition from treatment to survivorship, the responsibility of primary care providers (PCPs) versus oncology specialists is unclear...
  80. ncbi request reprint The economic cost of squamous cell cancer of the head and neck: findings from linked SEER-Medicare data
    Kathleen Lang
    Boston Health Economics Inc, Waltham, Mass, USA
    Arch Otolaryngol Head Neck Surg 130:1269-75. 2004
    ..To evaluate the excess mortality, resource use, and costs associated with squamous cell carcinoma of the head and neck (SCCHN) among elderly Medicare beneficiaries...
  81. ncbi request reprint Use of palliative radiotherapy among patients with metastatic non-small-cell lung cancer
    James A Hayman
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 69:1001-7. 2007
    ..The objective of this study was to examine the utilization patterns of palliative RT among elderly patients with Stage IV NSCLC and, in particular, to identify factors associated with its use...
  82. ncbi request reprint Trends in the treatment of acute myeloid leukaemia in the elderly
    Kathleen Lang
    Boston Health Economics, Inc, Waltham, Massachusetts 02451, USA
    Drugs Aging 22:943-55. 2005
    ..This study documents changes in treatment patterns and outcomes among elderly AML patients over the past decade...
  83. ncbi request reprint Looking back from death: the value of retrospective studies of end-of-life care
    Craig C Earle
    J Clin Oncol 24:838-40. 2006
  84. ncbi request reprint Does reimbursement influence chemotherapy treatment for cancer patients?
    Mireille Jacobson
    University of Michigan, Ann Arbor, USA
    Health Aff (Millwood) 25:437-43. 2006
    ..Providers who were more generously reimbursed, however, prescribed more-costly chemotherapy regimens to metastatic breast, colorectal, and lung cancer patients...
  85. ncbi request reprint Cancer survivorship research and guidelines: maybe the cart should be beside the horse
    Craig C Earle
    J Clin Oncol 25:3800-1. 2007
  86. pmc Towards using administrative databases to measure population-based indicators of quality of end-of-life care: testing the methodology
    Eva Grunfeld
    Cancer Outcomes Research Program, Cancer Care Nova Scotia, Dalhousie University, Halifax, Canada
    Palliat Med 20:769-77. 2006
    ..Using administrative data is an efficient, population-based method to monitor quality of care which can compliment other methods, such as qualitative and purposefully collected clinical data...
  87. ncbi request reprint Surgical mortality in patients with esophageal cancer: development and validation of a simple risk score
    Ewout W Steyerberg
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    J Clin Oncol 24:4277-84. 2006
    ..We aimed to develop and validate a simple risk score for surgical mortality that could be applied to administrative data...
  88. ncbi request reprint Racial differences in surgical evaluation, treatment, and outcome of locoregional esophageal cancer: a population-based analysis of elderly patients
    Ewout W Steyerberg
    Department of Public Health, Erasmus MC, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    J Clin Oncol 23:510-7. 2005
    ..We investigated racial disparities in access to surgical evaluation, receipt of surgery, and survival among elderly patients with locoregional esophageal cancer...

Research Grants7

  1. DEVELOPING QUALITY INDICATORS FOR ADVANCED CANCER CARE
    Craig Earle; Fiscal Year: 2000
    ..Payers and patients will benefit from these results when selecting providers, and institutions and networks will be able to use them to monitor performance. ..
  2. DEVELOPING QUALITY INDICATORS FOR ADVANCED CANCER CARE
    Craig Earle; Fiscal Year: 2001
    ..Payers and patients will benefit from these results when selecting providers, and institutions and networks will be able to use them to monitor performance. ..
  3. DEVELOPING QUALITY INDICATORS FOR ADVANCED CANCER CARE
    Craig Earle; Fiscal Year: 2002
    ..Payers and patients will benefit from these results when selecting providers, and institutions and networks will be able to use them to monitor performance. ..
  4. DEVELOPING QUALITY INDICATORS FOR ADVANCED CANCER CARE
    Craig Earle; Fiscal Year: 2004
    ..Once identified, reasons could be sought and appropriate interventions, such as increasing access to palliative services, could be instituted. ..
  5. DEVELOPING QUALITY INDICATORS FOR ADVANCED CANCER CARE
    Craig Earle; Fiscal Year: 2005
    ..Once identified, reasons could be sought and appropriate interventions, such as increasing access to palliative services, could be instituted. ..
  6. DEVELOPING QUALITY INDICATORS FOR ADVANCED CANCER CARE
    Craig Earle; Fiscal Year: 2006
    ..Once identified, reasons could be sought and appropriate interventions, such as increasing access to palliative services, could be instituted. ..
  7. DEVELOPING QUALITY INDICATORS FOR ADVANCED CANCER CARE
    Craig Earle; Fiscal Year: 2007
    ..Once identified, reasons could be sought and appropriate interventions, such as increasing access to palliative services, could be instituted. ..