Research Topics
| Taff JonesSummaryAffiliation: ID Biomedical Corp Country: Canada Publications
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Detail Information
Publications
A chimeric live attenuated vaccine against Japanese encephalitisTaff Jones
ID Biomedical Corp of Quebec, 7150 Frederick Banting, Montreal H4S 2A1, Quebec, Canada
Expert Rev Vaccines 3:243-8. 2004..It therefore appears to be a cost-effective prophylactic vaccine against this debilitating disease...
Intranasal proteosome-based respiratory syncytial virus (RSV) vaccines protect BALB/c mice against challenge without eosinophilia or enhanced pathologySonya L Cyr
McGill Center for Tropical Diseases, Montreal General Hospital, Montreal, Quebec H3G IA4, Canada
Vaccine 25:5378-89. 2007..Proteosome-based eRSV vaccines can therefore protect against RSV challenge in mice without increasing the risk of pulmonary immunopathologic responses...
Remune. Immune ResponseDerhsing Lai
Vincogen Corp, Yardley, PA 19067, USA
Curr Opin Investig Drugs 3:391-8. 2002..Analysts at Lehman Brothers predicted in September 2001, that the product would be launched onto the market with sales of US$150 million in 2004...
Resiquimod 3MTaff Jones
ID Biomedical Corp of Quebec, 7150 Frederick Banting, Suite 200, Ville St Laurent, Quebec H4S 2A1, Canada
Curr Opin Investig Drugs 4:214-8. 2003..The compound has also been investigated for the potential treatment of various other diseases, including other viral infections and eczema and as a vaccine adjuvant...
A nasal Proteosome influenza vaccine containing baculovirus-derived hemagglutinin induces protective mucosal and systemic immunityTaff Jones
ID Biomedical Corporation of Quebec, 7150 Frederick Banting, Suite 200, Ville Saint Laurent, Montreal, Que, Canada H4S 2A1
Vaccine 21:3706-12. 2003..n. Proteosome-rHA vaccine induced more complete protective immunity than the same doses of unformulated rHA given i.n. or i.m...
Technology evaluation: ChimeriVax-DEN, Acambis/AventisTaff Jones
ID Biomedical Corp, 7150 Frederick Banting, Montreal, H4S 2A1, Quebec, Canada
Curr Opin Mol Ther 6:443-50. 2004..Acambis, in collaboration with Aventis Pasteur, is developing a chimeric vaccine based on a recombinant yellow fever vaccine for the potential prevention of dengue virus infection. The vaccine is undergoing phase I clinical trials...
Intranasal Protollin/F1-V vaccine elicits respiratory and serum antibody responses and protects mice against lethal aerosolized plague infectionTaff Jones
ID Biomedical Corporation of Quebec, 525 Cartier Blvd West, Laval, Montreal, Que, Canada H7V 3S8
Vaccine 24:1625-32. 2006..Mice immunized intranasally with Protollin-F1-V were 100% protected against aerosol challenge with 170 LD50 of Y. pestis and 80% against 255 LD50...
Boostrix (GlaxoSmithKline)Taff Jones
ID Biomedical Corp of Quebec, Canada
IDrugs 8:656-61. 2005..GlaxoSmithKline plc has developed and launched Boostrix, a subunit vaccine for use in adolescents and adults as a booster immunization against diphtheria, tetanus and pertussis (DTPa) infections...
Peru-1 5 (AVANT)Taff Jones
ID Biomedical Corp of Quebec, 7150 Frederick Banting, Montreal H4S 2A1, Quebec, Canada
Curr Opin Investig Drugs 5:887-91. 2004..A phase II trial of Peru-15 was ongoing in June 2003, and as of September 2003 AVANT was planning a phase III trial in a developing country, and phase IIb and phase III challenge studies in travelers...
ChimeriVax-JE. AcambisTaff Jones
ID Biomedical Corp, 7150 Frederick Banting, Ville St Laurent, Quebec H4S 2A1, Canada
Curr Opin Investig Drugs 4:1019-22. 2003..By May 2003, Acambis had initiated a phase II trial in Australia...
Protollin: a novel adjuvant for intranasal vaccinesTaff Jones
ID Biomedical Corporation of Quebec, 7150 Frederick Banting, Ville St Laurent, Montreal, QC, Canada H4S 2A1
Vaccine 22:3691-7. 2004..Mice immunized with Protollin-rHA were completely protected against lethal challenge with influenza virus, demonstrating that Protollin is an effective mucosal adjuvant for prophylactic vaccines...
C57Bl/6 mice are protected from respiratory syncytial virus (RSV) challenge and IL-5 associated pulmonary eosinophilic infiltrates following intranasal immunization with Protollin-eRSV vaccineSonya L Cyr
McGill Center for Tropical Diseases, Montreal General Hospital, Montreal, Quebec, Canada H3G IA4
Vaccine 25:3228-32. 2007..This new model will permit us to dissect the respective roles of the TLR2 and TLR4 ligands contained in the vaccine using TLR knock-out animals established on the C57Bl/6 background...
Vaccines against human papilloma virusesTaff Jones
GSK Biologicals North America, Clinical Serology, 525 Cartier Boulevard West, Laval H7V 3S8, Quebec, Canada
Curr Opin Investig Drugs 7:699-701. 2006
Hepagene (PowderJect)Taff Jones
Intellivax International Inc, Ville St Laurent, Quebec, Canada
Curr Opin Investig Drugs 3:987-91. 2002..In December 1999, Lehman Brothers predicted that the product had a 50% chance of reaching the treatment (rather than prevention) market, with potential peak sales of US $600 million [352078]...
Varivax (Merck & Co)Taff Jones
Intellivax International Inc, Ville St Laurent, Quebec, Canada
Curr Opin Investig Drugs 3:54-7. 2002..Varivax II prevents the transmission of chickenpox with exactly the same safety and efficacy profile as Varivax; however, the new Varivax II has the advantage of being refrigerator-stable [371871]...
StaphVAX (Nabi)Taff Jones
Intellivax International Inc, Ville St Laurent, Quebec, Canada
Curr Opin Investig Drugs 3:48-50. 2002..At this time, Nabi was making plans for this second phase III trial, despite plans to appeal the FDA's decision [397729]...
Intranasal Protollin-formulated recombinant SARS S-protein elicits respiratory and serum neutralizing antibodies and protection in miceMary C Hu
GlaxoSmithKline Biologicals North America of Washington, 19204 North Creek Parkway, Bothell, WA 98011, USA
Vaccine 25:6334-40. 2007..Following live virus challenge of aged mice, no virus was detected in the lungs of intranasally immunized mice, in contrast to intramuscularly immunized mice whose lung virus titers were comparable to those observed in control mice...
Respiration consists of two acts: first inspiration, then expect(or)ationTaff Jones
Curr Opin Investig Drugs 9:833-5. 2008
Safety and immunogenicity of a Proteosome -trivalent inactivated influenza vaccine, given nasally to healthy adultsJoanne M Langley
Division of Infectious Diseases, Department of Pediatrics, Dalhousie University, Halifax, NS, Canada
Vaccine 24:1601-8. 2006..Further testing of this nasal influenza vaccine is warranted to determine its safety and immunogenicity in these populations and its efficacy in the prevention of clinical illness...
Vaccines to remember: managing health in our twilight yearsTaff Jones
Expert Rev Vaccines 3:497-500. 2004
IMVAMUNE, an attenuated modified vaccinia Ankara virus vaccine for smallpox infectionTaff Jones
MedImmune Inc, 297 N Bernardo Ave, Mountain View, CA 94043, USA
Curr Opin Mol Ther 10:407-17. 2008..Additional phase II trials were ongoing in these groups at the time of publication and phase III trials were planned for 2009...
