Marie France Hivert

Summary

Country: Canada

Publications

  1. doi request reprint Modified metabolic syndrome criteria for identification of patients at risk of developing diabetes and coronary heart diseases: longitudinal assessment via electronic health records
    Marie France Hivert
    Centre de Recherche Clinique Etienne Lebel, Centre Hospitalier Universitaire de Sherbrooke, Faculté Médecine, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Can J Cardiol 28:744-9. 2012
  2. pmc Identifying primary care patients at risk for future diabetes and cardiovascular disease using electronic health records
    Marie France Hivert
    General Medicine Division, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, USA
    BMC Health Serv Res 9:170. 2009
  3. pmc Common variants in the adiponectin gene (ADIPOQ) associated with plasma adiponectin levels, type 2 diabetes, and diabetes-related quantitative traits: the Framingham Offspring Study
    Marie France Hivert
    General Medicine Division, Massachusetts General Hospital, Boston, MA, USA
    Diabetes 57:3353-9. 2008
  4. ncbi request reprint TNFα dynamics during the oral glucose tolerance test vary according to the level of insulin resistance in pregnant women
    Laetitia Guillemette
    Department of Medicine L G, M L M C B, J L A P P, M F H, Universite de Sherbrooke, Quebec, Canada J1H 5N4 Centre de Recherché Clinique Étienne Le Bel of the Centre Hospitalier Universitaire de Sherbrooke M D, J Mo, J Mé, J L A, M F H, Sherbrooke, Quebec, Canada J1H 5N4 Department of Population Medicine M F H, Harvard Pilgrim Health Care Institute, Harvard Medical School, Boston, Massachusetts 02215 and Massachusetts General Hospital M F H, Boston, Massachusetts 02114
    J Clin Endocrinol Metab 99:1862-9. 2014
  5. pmc Lower adiponectin levels at first trimester of pregnancy are associated with increased insulin resistance and higher risk of developing gestational diabetes mellitus
    Marilyn Lacroix
    Faculty of Medicine, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Diabetes Care 36:1577-83. 2013
  6. pmc Common variants in and near IRS1 and subclinical cardiovascular disease in the Framingham Heart Study
    Soo Lim
    General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Atherosclerosis 229:149-54. 2013
  7. ncbi request reprint Epigenetic dysregulation of the IGF system in placenta of newborns exposed to maternal impaired glucose tolerance
    Véronique Desgagné
    Department of Biochemistry, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Epigenomics 6:193-207. 2014
  8. doi request reprint Validating metabolic syndrome through principal component analysis in a medically diverse, realistic cohort
    Francis Dusseault-Bélanger
    Departement de Mathematiques, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Metab Syndr Relat Disord 11:21-8. 2013
  9. pmc Diabetes Risk Perception and Intention to Adopt Healthy Lifest yles Among Primary Care Patients
    Marie France Hivert
    General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts, USA
    Diabetes Care 32:1820-2. 2009
  10. ncbi request reprint Epigenetic programming of obesity and diabetes by in utero exposure to gestational diabetes mellitus
    Stephanie May Ruchat
    Department of Biochemistry, Universite de Sherbrooke, Sherbrooke, Quebec, Canada ECOGENE 21 and Lipid Clinic, Chicoutimi Hospital, Saguenay, Quebec, Canada
    Nutr Rev 71:S88-94. 2013

Detail Information

Publications25

  1. doi request reprint Modified metabolic syndrome criteria for identification of patients at risk of developing diabetes and coronary heart diseases: longitudinal assessment via electronic health records
    Marie France Hivert
    Centre de Recherche Clinique Etienne Lebel, Centre Hospitalier Universitaire de Sherbrooke, Faculté Médecine, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Can J Cardiol 28:744-9. 2012
    ..We developed and tested an algorithm to identify patients at risk for future diabetes or coronary heart disease (CHD) events using electronic health records (EHRs) at the Centre Hospitalier Universitaire de Sherbrooke (CHUS)...
  2. pmc Identifying primary care patients at risk for future diabetes and cardiovascular disease using electronic health records
    Marie France Hivert
    General Medicine Division, Massachusetts General Hospital, and Harvard Medical School, Boston, MA, USA
    BMC Health Serv Res 9:170. 2009
    ..Prevention of diabetes and coronary heart disease (CHD) is possible but identification of at-risk patients for targeting interventions is a challenge in primary care...
  3. pmc Common variants in the adiponectin gene (ADIPOQ) associated with plasma adiponectin levels, type 2 diabetes, and diabetes-related quantitative traits: the Framingham Offspring Study
    Marie France Hivert
    General Medicine Division, Massachusetts General Hospital, Boston, MA, USA
    Diabetes 57:3353-9. 2008
    ..Using comprehensive linkage disequilibrium mapping, we genotyped single nucleotide polymorphisms (SNPs) in ADIPOQ to evaluate the association of common variants with adiponectin levels and risk of diabetes...
  4. ncbi request reprint TNFα dynamics during the oral glucose tolerance test vary according to the level of insulin resistance in pregnant women
    Laetitia Guillemette
    Department of Medicine L G, M L M C B, J L A P P, M F H, Universite de Sherbrooke, Quebec, Canada J1H 5N4 Centre de Recherché Clinique Étienne Le Bel of the Centre Hospitalier Universitaire de Sherbrooke M D, J Mo, J Mé, J L A, M F H, Sherbrooke, Quebec, Canada J1H 5N4 Department of Population Medicine M F H, Harvard Pilgrim Health Care Institute, Harvard Medical School, Boston, Massachusetts 02215 and Massachusetts General Hospital M F H, Boston, Massachusetts 02114
    J Clin Endocrinol Metab 99:1862-9. 2014
    ..Controversies exist concerning the role of TNFα in gestational insulin resistance. We investigated the interrelations between TNFα and insulin resistance in a large population-based cohort of pregnant women...
  5. pmc Lower adiponectin levels at first trimester of pregnancy are associated with increased insulin resistance and higher risk of developing gestational diabetes mellitus
    Marilyn Lacroix
    Faculty of Medicine, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Diabetes Care 36:1577-83. 2013
    ....
  6. pmc Common variants in and near IRS1 and subclinical cardiovascular disease in the Framingham Heart Study
    Soo Lim
    General Medicine Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    Atherosclerosis 229:149-54. 2013
    ..We tested the hypothesis that variants at this locus are associated with subclinical atherosclerosis traits...
  7. ncbi request reprint Epigenetic dysregulation of the IGF system in placenta of newborns exposed to maternal impaired glucose tolerance
    Véronique Desgagné
    Department of Biochemistry, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Epigenomics 6:193-207. 2014
    ....
  8. doi request reprint Validating metabolic syndrome through principal component analysis in a medically diverse, realistic cohort
    Francis Dusseault-Bélanger
    Departement de Mathematiques, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Metab Syndr Relat Disord 11:21-8. 2013
    ....
  9. pmc Diabetes Risk Perception and Intention to Adopt Healthy Lifest yles Among Primary Care Patients
    Marie France Hivert
    General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts, USA
    Diabetes Care 32:1820-2. 2009
    ..To examine perceived risk of developing diabetes in primary care patients...
  10. ncbi request reprint Epigenetic programming of obesity and diabetes by in utero exposure to gestational diabetes mellitus
    Stephanie May Ruchat
    Department of Biochemistry, Universite de Sherbrooke, Sherbrooke, Quebec, Canada ECOGENE 21 and Lipid Clinic, Chicoutimi Hospital, Saguenay, Quebec, Canada
    Nutr Rev 71:S88-94. 2013
    ....
  11. pmc A genome-wide association study reveals variants in ARL15 that influence adiponectin levels
    J Brent Richards
    Departments of Medicine, Human Genetics, and Epidemiology and Biostatistics, Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    PLoS Genet 5:e1000768. 2009
    ..Expression studies in humans indicated that ARL15 is well-expressed in skeletal muscle. These findings identify a novel protein, ARL15, which influences circulating adiponectin levels and may impact upon CHD risk...
  12. pmc A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
    Alisa K Manning
    Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA
    Nat Genet 44:659-69. 2012
    ..The discovery of these loci will aid further characterization of the role of insulin resistance in T2D pathophysiology...
  13. pmc Higher adiponectin levels predict greater weight gain in healthy women in the Nurses' Health Study
    Marie France Hivert
    General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts, USA
    Obesity (Silver Spring) 19:409-15. 2011
    ..High adiponectin production by adipocytes might be a sign of "healthy" adipose tissue with further capacity to store fat...
  14. pmc Polygenic type 2 diabetes prediction at the limit of common variant detection
    Jason L Vassy
    Harvard Medical School, Boston, MASection of General Internal Medicine, VA Boston Healthcare System, Boston, MADivision of General Internal Medicine and Primary Care, Brigham and Women s Hospital, Boston, MA
    Diabetes 63:2172-82. 2014
    ..Further optimization of polygenic prediction may require novel analytic methods, including less common as well as functional variants...
  15. pmc Intergenerational cycle of obesity and diabetes: how can we reduce the burdens of these conditions on the health of future generations?
    Marie Claude Battista
    Division of Endocrinology, Department of Medicine, University of Sherbrooke, Sherbrooke, QC, Canada
    Exp Diabetes Res 2011:596060. 2011
    ..The main interventions designed to reduce maternal obesity and GDM and their ability to break the vicious circle that perpetuates the transmission of obesity and metabolic conditions to the next generations are also addressed...
  16. doi request reprint Lower leptin levels are associated with higher risk of weight gain over 2 years in healthy young adults
    Catherine Allard
    a Centre de recherche clinique Etienne Le Bel, Department of Medicine, Universite de Sherbrooke, QC J1H 5N4, Canada
    Appl Physiol Nutr Metab 38:280-5. 2013
    ..02). In the subsample measured at 4 years (n = 63), baseline leptin levels were not associated with 4-year weight changes. Lower leptin levels are associated with a higher risk of weight gain over 2 years in healthy young adults...
  17. pmc Updated genetic score based on 34 confirmed type 2 diabetes Loci is associated with diabetes incidence and regression to normoglycemia in the diabetes prevention program
    Marie France Hivert
    Division of Endocrinology, Department of Medicine, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Diabetes 60:1340-8. 2011
    ..We tested if a GRS based on an updated list of 34 type 2 diabetes-associated loci predicted progression to diabetes or regression toward normal glucose regulation (NGR) in the Diabetes Prevention Program (DPP)...
  18. pmc Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
    Richa Saxena
    Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
    Nat Genet 42:142-8. 2010
    ..Of the three newly implicated loci (GIPR, ADCY5 and VPS13C), only ADCY5 was found to be associated with type 2 diabetes in collaborating studies (n = 35,869 cases, 89,798 controls, OR = 1.12, 95% CI 1.09-1.15, P = 4.8 x 10(-18))...
  19. doi request reprint Ghrelin levels are associated with hunger as measured by the Three-Factor Eating Questionnaire in healthy young adults
    Fabienne Langlois
    Department of Medicine, Division of Endocrinology, Faculte de Medecine et des Sciences de la Sante, Université de Sherbrooke and Centre de recherche Clinique Étienne Le Bel, Centre Hospitalier Universitaire de Sherbrooke, Quebec, Canada
    Physiol Behav 104:373-7. 2011
    ..In conclusion, we demonstrated that ghrelin, a biological marker, is associated with self-reported perception of hunger, independently of anthropometric measures and lifestyle...
  20. pmc The association of tumor necrosis factor alpha receptor 2 and tumor necrosis factor alpha with insulin resistance and the influence of adipose tissue biomarkers in humans
    Marie France Hivert
    Harvard Medical School, Boston, MA 02115, USA
    Metabolism 59:540-6. 2010
    ..We conclude that, in a representative community sample, measures of TNFalpha activity are associated with insulin resistance, even after accounting for central adiposity and other adipose tissue biomarkers...
  21. pmc Susceptibility to type 2 diabetes mellitus-from genes to prevention
    Marie France Hivert
    Department of Population Medicine, Harvard Pilgrim Health Care Institute, Harvard Medical School, 50 Staniford Street, 9th Floor, Boston, MA 02114, USA
    Nat Rev Endocrinol 10:198-205. 2014
    ..Future studies should investigate the role of genetics for both T2DM prediction and prevention in young populations in the hope of reducing disease burden for future generations. ..
  22. pmc Association of variants in RETN with plasma resistin levels and diabetes-related traits in the Framingham Offspring Study
    Marie France Hivert
    General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts, USA
    Diabetes 58:750-6. 2009
    ..Using comprehensive linkage disequilibrium mapping, we genotyped tag single nucleotide polymorphisms (SNPs) in RETN and tested associations with plasma resistin levels, risk of diabetes, and glycemic traits...
  23. pmc Placental adiponectin gene DNA methylation levels are associated with mothers' blood glucose concentration
    Luigi Bouchard
    Department of Biochemistry, Universite de Sherbrooke, Sherbrooke, Quebec, Canada
    Diabetes 61:1272-80. 2012
    ..Because adiponectin is suspected to have insulin-sensitizing proprieties, these epigenetic adaptations have the potential to induce sustained glucose metabolism changes in the mother and offspring later in life...
  24. doi request reprint Maternal/fetal determinants of insulin resistance in women during pregnancy and in offspring over life
    Marilyn Lacroix
    Department of Medicine, Universite de Sherbrooke, 3001, 12e Ave Nord, Sherbrooke, QC, Canada
    Curr Diab Rep 13:238-44. 2013
    ..We are also highlighting recent reports of the potential mechanisms involved in 'programming' of insulin resistance such as epigenetic modulation...
  25. pmc Genetic susceptibility testing for chronic disease and intention for behavior change in healthy young adults
    Jason L Vassy
    Section of General Internal Medicine, VA Boston Healthcare System, 150 Huntington Avenue, Bldg 9, STE 425, Boston, MA, 02130, USA
    J Community Genet 4:263-71. 2013
    ..To be effective, genetic risk testing in young adults may need to be coupled with other strategies to enable behavior change...