- Clinical hypotension with co-prescription of macrolide antibiotics and calcium-channel blockers in haemodialysis patients: a retrospective chart reviewSwapnil Hiremath
The Renal Hypertension Unit, Division of Nephrology, Department of Medicine, University of Ottawa, Ottawa, ON, Canada
Drug Saf 36:989-93. 2013..Since these drugs are frequently used in the haemodialysis population, we studied the effect of their co-prescription on actual blood pressure...
- Prevention of contrast-induced acute kidney injury: is simple oral hydration similar to intravenous? A systematic review of the evidenceSwapnil Hiremath
Division of Nephrology, Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada
PLoS ONE 8:e60009. 2013..For logistical ease, the oral route is an alternative to the intravenous. The objective of this study was to compare the efficacy of the oral to the intravenous route in prevention of contrast-induced acute kidney injury...
- Should the arteriovenous fistula be created before starting dialysis?: a decision analytic approachSwapnil Hiremath
Division of Nephrology, Kidney Research Center, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada
PLoS ONE 6:e28453. 2011..The aim of this study was to determine the optimal vascular access referral strategy for stage 4 (glomerular filtration rate <30 ml/min/1.73 m(2)) chronic kidney disease patients using a decision analytic framework...
- Antiplatelet medications in hemodialysis patients: a systematic review of bleeding ratesSwapnil Hiremath
Division of Nephrology, University of Ottawa, Kidney Research Centre, Ottawa, Ontario, Canada
Clin J Am Soc Nephrol 4:1347-55. 2009..However, these patients are also at increased risk of bleeding compared with the general population, and an aim was made to quantify this risk with antiplatelet agents...
- Implantable defibrillators improve survival in end-stage renal disease: results from a multi-center registrySwapnil Hiremath
Kidney Research Centre, Ottawa Hospital Research Institute, Ont, Canada
Am J Nephrol 32:305-10. 2010..We aimed to assess the survival effect of an ICD in ESRD patients with left ventricular dysfunction...
- Accuracy of cystatin C-based estimates of glomerular filtration rate in kidney transplant recipients: a systematic reviewGavin Harman
Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
Nephrol Dial Transplant 28:741-57. 2013..The overall performance of cystatin C-based equations in kidney transplantation is unclear with conflicting results between studies...
- Spot urine protein measurements: are these accurate in kidney transplant recipients?Ayub Akbari
Division of Nephrology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada
Transplantation 94:389-95. 2012..Aside from tests of correlation, there has been little evaluation of these measurements in kidney transplantation...
- Left ventricular growth after 1 year of haemodialysis does not correlate with arteriovenous access flow: a prospective cohort studySwapnil Hiremath
Division of Nephrology, Kidney Research Centre, Ottawa Health Research Institute, Ottawa, Ontario, Canada
Nephrol Dial Transplant 25:2656-61. 2010..The purpose of this study was to determine if blood flow through an arteriovenous (AV) access contributes to an increase in left ventricular mass (LVM) that may increase the risk of congestive heart failure...
- Spironolactone for difficult to control hypertension in chronic kidney disease: an analysis of safety and efficacyJodi Heshka
Department of Medicine, University of Ottawa, Ottawa, Ontario
J Am Soc Hypertens 4:295-301. 2010..It is associated with a modest rise in serum potassium, which is more pronounced among those with glomerular filtration rate below 45 mL/minute...
- Factors influencing the prevalence of central venous catheter use in a Canadian haemodialysis centreJanet Graham
Division of Nephrology, Department of Medicine, The Ottawa Hospital, Ottawa Health Research Institute, University of Ottawa, Ottawa, Ontario, Canada
Nephrol Dial Transplant 23:3585-91. 2008..We studied factors influencing the choice of access in a prevalent HD population at a Canadian centre...
- Increased urinary angiotensin-converting enzyme 2 in renal transplant patients with diabetesFengxia Xiao
Division of Nephrology, Department of Medicine, Ottawa Hospital Research Institute, Kidney Research Centre, University of Ottawa, Ottawa, Ontario, Canada
PLoS ONE 7:e37649. 2012..Urinary ACE2 could be a marker of renal renin-angiotensin system activation in these patients...
- Adherence to blood pressure-lowering drugs and resistant hypertension: should trial of direct observation therapy be part of preassessment for renal denervation?Marcel Ruzicka
Division of Nephrology, University of Ottawa, Ottawa, Ontario, Canada Division of Cardiology, University of Ottawa Heart Institute, Ottawa, Ontario, Canada Electronic address
Can J Cardiol 29:1741.e1-3. 2013..The novel teaching points are that evaluation of nonadherence to drug therapy is a crucial component in diagnosing resistant hypertension before RDN and that DOT may be extremely useful in avoiding an unnecessary and costly procedure. ..
- Systematic review and meta-analysis of incidence, prevalence and outcomes of atrial fibrillation in patients on dialysisDeborah Zimmerman
Department of Medicine, Ottawa Hospital, University of Ottawa, Canada
Nephrol Dial Transplant 27:3816-22. 2012..The risks and benefits of warfarin anticoagulation need to be defined as the risk of bleeding in ESRD patients may overwhelm the benefits of embolic stroke prevention. We undertook a systematic literature review to clarify these issues...
- BpTRUth: do automated blood pressure monitors outperform mercury?Cedric Edwards
Renal Hypertension Unit, Division of Nephrology, Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada Electronic address
J Am Soc Hypertens 7:448-53. 2013..The increased detection of white coat effect appears related to systematic downward bias by BpTRU. As a result, detection of masked effect is undermined by BpTRU. ..
- What is the feasibility of implementing effective sodium reduction strategies to treat hypertension in primary care settings? A systematic reviewMarcel Ruzicka
aDivision of Nephrology, The Ottawa Hospital bDivision of Cardiology, University of Ottawa Heart Institute cDivision of Angiology Vascular Medicine, Department of Internal Medicine II, Medical University Vienna dDivision of Prevention and Rehabilitation eBerkman Library, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
J Hypertens 32:1388-94. 2014..To evaluate whether efficacious counseling methods on sodium restriction can be successfully incorporated into primary care models for the management of hypertension...
- Canadian Society of Nephrology commentary on the 2012 KDIGO clinical practice guideline for the management of blood pressure in CKDMarcel Ruzicka
Division of Nephrology, University of Ottawa, Ottawa, Ontario Electronic address
Am J Kidney Dis 63:869-87. 2014..Finally, in the absence of evidence for a lower BP target, the CSN Work Group concurs with the CHEP recommendation to target BP<140/90 mm Hg for nondiabetic patients with a kidney transplant...