Chao Wu Xiao

Summary

Affiliation: Health Canada
Country: Canada

Publications

  1. ncbi request reprint Dietary soy protein isolate and isoflavones modulate hepatic thyroid hormone receptors in rats
    Chao Wu Xiao
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, ON, Canada K1A 0L2
    J Nutr 134:743-9. 2004
  2. ncbi request reprint Nuclear receptors: potential biomarkers for assessing physiological functions of soy proteins and phytoestrogens
    Chao Wu Xiao
    Health Canada, Health Products and Food Branch, Nutrition Research Division, Food Directorate, Ottawa, ON, Canada
    J AOAC Int 89:1207-14. 2006
  3. ncbi request reprint Health effects of soy protein and isoflavones in humans
    Chao Wu Xiao
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, 2203E Banting Research Centre, Ottawa, Canada
    J Nutr 138:1244S-9S. 2008
  4. ncbi request reprint Dietary soy protein isolate modifies hepatic retinoic acid receptor-beta proteins and inhibits their DNA binding activity in rats
    Chao Wu Xiao
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, 2203C Banting Research Centre, Ottawa, ON, Canada K1A 0L2
    J Nutr 137:1-6. 2007
  5. ncbi request reprint Effect of soy proteins and isoflavones on lipid metabolism and involved gene expression
    Chao Wu Xiao
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, 2203C Banting Research Centre, Ottawa, ON, Canada K1A 0L2
    Front Biosci 13:2660-73. 2008
  6. ncbi request reprint Tissue-specific regulation of acetyl-CoA carboxylase gene expression by dietary soya protein isolate in rats
    Chao Wu Xiao
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, 2203C Banting Research Centre, Ottawa, ON, Canada K1A 0L2
    Br J Nutr 95:1048-54. 2006
  7. ncbi request reprint Consumption of soy protein isolate modulates the phosphorylation status of hepatic ATPase/ATP synthase beta protein and increases ATPase activity in rats
    Jie Mei
    Nutrition Research Division, Health Products and Food Branch, Health Canada, Ottawa, Canada K1A 0L2
    J Nutr 137:2029-35. 2007
  8. ncbi request reprint Soy protein isolate increases hepatic thyroid hormone receptor content and inhibits its binding to target genes in rats
    Wenxin Huang
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, Banting Research Centre, Ottawa, ON, Canada K1A 0L2
    J Nutr 135:1631-5. 2005
  9. doi request reprint Impact of dietary protein on lipid metabolism in hamsters is source-dependent and associated with changes in hepatic gene expression
    Alfred Aziz
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, PL 2203E, 251 Sir Frederick Banting Driveway, Ottawa K1A 0K9, ON, Canada
    Br J Nutr 100:503-11. 2008
  10. doi request reprint Sex- and age-specific immunomodulatory effects of dietary soya protein isolate and isoflavones in rats
    Stephen M Cornish
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, ON, Canada
    Br J Nutr 106:683-7. 2011

Collaborators

Detail Information

Publications13

  1. ncbi request reprint Dietary soy protein isolate and isoflavones modulate hepatic thyroid hormone receptors in rats
    Chao Wu Xiao
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, ON, Canada K1A 0L2
    J Nutr 134:743-9. 2004
    ..The SPI-induced TRbeta1 may play a role in mediating the hypocholesterolemic and lipid-lowering actions of soy protein...
  2. ncbi request reprint Nuclear receptors: potential biomarkers for assessing physiological functions of soy proteins and phytoestrogens
    Chao Wu Xiao
    Health Canada, Health Products and Food Branch, Nutrition Research Division, Food Directorate, Ottawa, ON, Canada
    J AOAC Int 89:1207-14. 2006
    ....
  3. ncbi request reprint Health effects of soy protein and isoflavones in humans
    Chao Wu Xiao
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, 2203E Banting Research Centre, Ottawa, Canada
    J Nutr 138:1244S-9S. 2008
    ..Overall, existing data are inconsistent or inadequate in supporting most of the suggested health benefits of consuming soy protein or ISF...
  4. ncbi request reprint Dietary soy protein isolate modifies hepatic retinoic acid receptor-beta proteins and inhibits their DNA binding activity in rats
    Chao Wu Xiao
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, 2203C Banting Research Centre, Ottawa, ON, Canada K1A 0L2
    J Nutr 137:1-6. 2007
    ....
  5. ncbi request reprint Effect of soy proteins and isoflavones on lipid metabolism and involved gene expression
    Chao Wu Xiao
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, 2203C Banting Research Centre, Ottawa, ON, Canada K1A 0L2
    Front Biosci 13:2660-73. 2008
    ....
  6. ncbi request reprint Tissue-specific regulation of acetyl-CoA carboxylase gene expression by dietary soya protein isolate in rats
    Chao Wu Xiao
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, 2203C Banting Research Centre, Ottawa, ON, Canada K1A 0L2
    Br J Nutr 95:1048-54. 2006
    ..The results indicate that the effect of SPI is tissue-specific and that alteration of ACC gene expression rather than phosphorylation status may play a major role in the regulation of ACC activities by soya proteins...
  7. ncbi request reprint Consumption of soy protein isolate modulates the phosphorylation status of hepatic ATPase/ATP synthase beta protein and increases ATPase activity in rats
    Jie Mei
    Nutrition Research Division, Health Products and Food Branch, Health Canada, Ottawa, Canada K1A 0L2
    J Nutr 137:2029-35. 2007
    ..These results suggest that consumption of soy proteins increases hepatic ATPase activity, which might be a consequence of increased dephosphorylation or decreased phosphorylation of the mitochondrial ATPase/ATP synthase beta protein...
  8. ncbi request reprint Soy protein isolate increases hepatic thyroid hormone receptor content and inhibits its binding to target genes in rats
    Wenxin Huang
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, Banting Research Centre, Ottawa, ON, Canada K1A 0L2
    J Nutr 135:1631-5. 2005
    ..Modulation of hepatic TRbeta1, a key regulator of gene expression involved in lipid metabolism, by SPI may be a novel mechanism by which soy components lower blood lipid level and exert their hypocholesterolemic actions...
  9. doi request reprint Impact of dietary protein on lipid metabolism in hamsters is source-dependent and associated with changes in hepatic gene expression
    Alfred Aziz
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, PL 2203E, 251 Sir Frederick Banting Driveway, Ottawa K1A 0K9, ON, Canada
    Br J Nutr 100:503-11. 2008
    ..These results show that the impact of dietary protein on lipid metabolism is source-dependent and associated with changes in mRNA abundances of key hepatic enzymes and receptors...
  10. doi request reprint Sex- and age-specific immunomodulatory effects of dietary soya protein isolate and isoflavones in rats
    Stephen M Cornish
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, ON, Canada
    Br J Nutr 106:683-7. 2011
    ..However, the physiological significance of these immune responses remains to be determined...
  11. doi request reprint Determination of isoflavones in rat serum using liquid chromatography-tandem mass spectrometry with a highly efficient core-shell column
    Jennilee M A Gavina
    Exposure and Biomonitoring Division, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, ON, Canada
    Anal Bioanal Chem 405:2643-51. 2013
    ..The developed method was applied to the analysis of 32 serum samples and was shown to be specific, sensitive and reproducible...
  12. doi request reprint Soy extracts suppressed iodine uptake and stimulated the production of autoimmunogen in rat thyrocytes
    Lisa Tran
    Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, Ontario, K1A 0K9, Canada
    Exp Biol Med (Maywood) 238:623-30. 2013
    ..Soy ISF, particularly genistein, induced the production of P40, which might be responsible for the higher incidence of ATD reported in soy infant formula-fed children. ..
  13. ncbi request reprint Nuclear factor kappaB-mediated induction of Flice-like inhibitory protein prevents tumor necrosis factor alpha-induced apoptosis in rat granulosa cells
    Chao Wu Xiao
    Reproductive Biology Unit and Division of Reproductive Medicine, University of Ottawa, Ottawa Health Research Institute, The Ottawa Hospital Civic Campus, 725 Parkdale Avenue, Ottawa, Ontario, Canada K1Y 4E9
    Biol Reprod 67:436-41. 2002
    ..TNFalpha-induced, NFkappaB-mediated FLIP(S) expression is a determinant of granulosa cell fate...