Affiliation: Health Canada
- Oxidative burden of fine particulate air pollution and risk of cause-specific mortality in the Canadian Census Health and Environment Cohort (CanCHEC)Scott Weichenthal
Health Canada, Ottawa, Ontario, Canada Electronic address
Environ Res 146:92-9. 2016..Fine particulate air pollution (PM2.5) is known to contribute to cardiorespiratory mortality but it is not clear how PM2.5 oxidative burden (i.e. the ability of PM2.5 to cause oxidative stress) may influence long-term mortality risk...
- A land use regression model for ambient ultrafine particles in Montreal, Canada: A comparison of linear regression and a machine learning approachScott Weichenthal
Air Health Science Division, Health Canada, Ottawa, Canada Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, Canada Electronic address
Environ Res 146:65-72. 2016..However, differences in predictive performance were not statistically significant when evaluated using the cross-validation procedure. ..
- Characterizing the spatial distribution of ambient ultrafine particles in Toronto, Canada: A land use regression modelScott Weichenthal
Air Health Science Division, Health Canada, Ottawa, Canada Electronic address
Environ Pollut 208:241-8. 2016..This model will be used to evaluate the chronic health effects of UFPs using population-based cohorts in the Toronto area. ..
- The impact of a landfill fire on ambient air quality in the north: A case study in Iqaluit, CanadaScott Weichenthal
Water and Air Quality Bureau, Health Canada, Canada Electronic address
Environ Res 142:46-50. 2015..Other pollutants changed less dramatically. Our findings suggest that airborne concentrations of potentially harmful substances may be elevated during landfill fires even when criteria air pollutants remain largely unchanged...
- Exposure to traffic-related air pollution during physical activity and acute changes in blood pressure, autonomic and micro-vascular function in women: a cross-over studyScott Weichenthal
Air Health Science Division, Health Canada, 269 Laurier Avenue West, K1A 0K9, Ottawa, ON, Canada
Part Fibre Toxicol 11:70. 2014..Traffic-related air pollution may contribute to cardiovascular morbidity. In urban areas, exposures during physical activity are of interest owing to increased breathing rates and close proximity to vehicle emissions...
- Estimating risk of emergency room visits for asthma from personal versus fixed site measurements of NO2Scott Weichenthal
Air Health Effects Science Division, Health Canada, Ottawa, Canada Department of Environmental and Occupational Health, University of Montreal, Montreal, Canada Electronic address
Environ Res 137:323-8. 2015..We examined the impact of data source and exposure measurement error for ambient NO2 on risk estimates derived from a case-crossover study of emergency room visits for asthma in Windsor, Canada between 2002 and 2009...
- Characterizing the impact of traffic and the built environment on near-road ultrafine particle and black carbon concentrationsScott Weichenthal
Air Health Science Division, Health Canada, 269 Laurier Ave West, Ottawa, Ontario, Canada K1A 0K9 Electronic address
Environ Res 132:305-10. 2014..We examined the relationship between near road UFPs and several traffic and built environment factors to identify predictors that may be used to estimate exposures in population-based studies. Black carbon (BC) was also examined...
- A randomized double-blind crossover study of indoor air filtration and acute changes in cardiorespiratory health in a First Nations communityS Weichenthal
Health Canada, Health Canada Air Health Effects Science Division, Ottawa, ON, Canada
Indoor Air 23:175-84. 2013..Consistent inverse associations were also observed between indoor PM2.5 and lung function. In general, our findings suggest that reducing indoor PM2.5 may contribute to improved lung function in First Nations communities...
- PM2.5, oxidant defence and cardiorespiratory health: a reviewScott A Weichenthal
Health Canada, Air Health Effects Science Division, Ottawa, Canada
Environ Health 12:40. 2013..Therefore, further evaluation is required to determine how this metric may be incorporated in ambient air quality management...
- Personal exposure to specific volatile organic compounds and acute changes in lung function and heart rate variability among urban cyclistsScott Weichenthal
Health Canada, Air Health Sciences Division, Ottawa, ON, Canada
Environ Res 118:118-23. 2012..Few studies have examined the acute cardiorespiratory effects of specific volatile organic compound (VOC) exposures from traffic pollution...
- Selected physiological effects of ultrafine particles in acute cardiovascular morbidityScott Weichenthal
Health Canada, Air Health Effects Science Division, 269 Laurier Avenue West, 3rd Floor, AL 4903C, Ottawa, ON, Canada K1A 0K9
Environ Res 115:26-36. 2012..In addition, effort should be made to include more women in studies of the acute cardiovascular effects of UFPs as findings to date generally reflect responses in men...
- A review of pesticide exposure and cancer incidence in the agricultural health study cohortScott Weichenthal
Cien Saude Colet 17:255-70. 2012..Continued follow-up is needed to clarify associations reported to date. In particular, further evaluation of registered pesticides is warranted...
- A review of pesticide exposure and cancer incidence in the Agricultural Health Study cohortScott Weichenthal
Health Canada, Ottawa, Ontario, Canada
Environ Health Perspect 118:1117-25. 2010..We reviewed epidemiologic evidence related to occupational pesticide exposures and cancer incidence in the Agricultural Health Study (AHS) cohort...
- Traffic-related air pollution and acute changes in heart rate variability and respiratory function in urban cyclistsScott Weichenthal
Air Health Sciences Division, Health Canada, Ottawa, Canada
Environ Health Perspect 119:1373-8. 2011..Few studies have examined the acute health effects of air pollution exposures experienced while cycling in traffic...
- Metal composition of fine particulate air pollution and acute changes in cardiorespiratory physiologySabit Cakmak
Population Studies Division, Environmental Health Science and Research Bureau, Health Canada, 50 Columbine Driveway, Ottawa, Ontario K1A 0K9, Canada Electronic address
Environ Pollut 189:208-14. 2014..Studying the physiologic effects of components of fine particulate mass (PM2.5) could contribute to a better understanding of the nature of toxicity of air pollution...
- Determinants of ultrafine particle exposures in transportation environments: findings of an 8-month survey conducted in Montréal, CanadaScott Weichenthal
Department of Epidemiology, Biostatistics and Occupational Health, Faculty of Medicine, McGill University, Montreal, Canada
J Expo Sci Environ Epidemiol 18:551-63. 2008..65) and automobile (r=0.77) routes. Further research is required to incorporate variables such as traffic density and vehicle ventilation settings into the models presented...
- A web-based route planning tool to reduce cyclists' exposures to traffic pollution: a case study in Montreal, CanadaMarianne Hatzopoulou
McGill University, Department of Civil Engineering, Montreal, Quebec, Canada
Environ Res 123:58-61. 2013..1 ppb for a single trip. Cumulative exposure levels (ppb km) decreased by approximately 4%. In general, the benefits of decreased exposure could be achieved with little increase (less than 1 km) in the overall route length...
- The impact of traffic volume, composition, and road geometry on personal air pollution exposures among cyclists in Montreal, CanadaMarianne Hatzopoulou
Department of Civil Engineering, McGill University, Montreal, Quebec, Canada
J Expo Sci Environ Epidemiol 23:46-51. 2013..Further evaluation is required, however, as the impact of separate cycling lanes and/or traffic counts on personal exposures may vary between regions...
- Characterizing and predicting ultrafine particle counts in Canadian classrooms during the winter months: model development and evaluationScott Weichenthal
Department of Epidemiology, Biostatistics and Occupational Health, Faculty of Medicine, McGill University, 1130 Pine Avenue West, Montreal, Quebec, Canada
Environ Res 106:349-60. 2008..In general, our findings suggest that reasonable estimates of classroom UFP counts may be obtained from outdoor UFP data but that the accuracy of such estimates are limited in the presence of indoor UFP sources...
- Risk estimates of mortality attributed to low concentrations of ambient fine particulate matter in the Canadian community health survey cohortLauren Pinault
Health Analysis Division, Statistics Canada, 100 Tunney s Pasture Driveway, Ottawa, ON, K1A 0T6, Canada
Environ Health 15:18. 2016..Studies evaluating the health risks of exposure to low concentrations of PM2.5 are limited. Further, many existing studies lack individual-level information on potentially important behavioural confounding factors...
- Bayesian estimation of the probability of asbestos exposure from lung fiber countsScott Weichenthal
Department of Epidemiology, Biostatistics and Occupational Health, McGill University, 1020 Pine Avenue West, Montreal, Quebec, H3A 1A2, Canada
Biometrics 66:603-12. 2010....
- Pesticides and childhood cancer: an update of Zahm and Ward's 1998 reviewClaire Infante-Rivard
Department of Epidemiology, Biostatistics, and Occupational Health, Faculty of Medicine, McGill University, Montreal, Quebec, Canada
J Toxicol Environ Health B Crit Rev 10:81-99. 2007....
- Long-term exposure to fine particulate matter: association with nonaccidental and cardiovascular mortality in the agricultural health study cohortScott Weichenthal
Health Canada, Air Health Sciences Division, Ottawa, Ontario, Canada
Environ Health Perspect 122:609-15. 2014..Few studies have examined the relationship between long-term exposure to ambient fine particulate matter (PM2.5) and nonaccidental mortality in rural populations...
- A New Method to Jointly Estimate the Mortality Risk of Long-Term Exposure to Fine Particulate Matter and its ComponentsDan L Crouse
Environmental Health Science and Research Bureau, Health Canada, Ottawa, Ontario, Canada
Sci Rep 6:18916. 2016..This is required to fully understand the health benefits associated with strategies to improve air quality that may result in complex changes not only in PM2.5 concentration, but also in the distribution of particle components. ..
- In-vehicle exposures to particulate air pollution in Canadian metropolitan areas: the urban transportation exposure studyScott Weichenthal
Air Health Science Division, Health Canada, Ottawa, Ontario K1A 0K9, Canada
Environ Sci Technol 49:597-605. 2015..Our findings suggest that vehicle commuters experience increased exposure to air pollutants and that traffic characteristics, land use, road types, and meteorology are important determinants of these exposures. ..
- Indoor ultrafine particle exposures and home heating systems: a cross-sectional survey of Canadian homes during the winter monthsScott Weichenthal
Department of Epidemiology, Biostatistics and Occupational Health, Faculty of Medicine, McGill University, Quebec, Canada
J Expo Sci Environ Epidemiol 17:288-97. 2007..In general, our findings suggest that home heating systems are not important determinants of indoor UFP exposures...
- Investigating the Use Of Portable Air Pollution Sensors to Capture the Spatial Variability Of Traffic-Related Air PollutionLaure Deville Cavellin
Civil Engineering, McGill University, 817 Rue Sherbrooke Ouest, Montreal, Quebec H3A 2K6, Canada
Environ Sci Technol 50:313-20. 2016..However, the sensors suggest a good performance with respect to capturing the spatial variability in NO2 and O3 and are very convenient to use, having great potential for capturing temporal variability. ..
- Exposure to air pollution near a steel plant and effects on cardiovascular physiology: a randomized crossover studyLing Liu
Environmental Health Science and Research Bureau, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada Electronic address
Int J Hyg Environ Health 217:279-86. 2014..Iron and steel industry is an important source of air pollution emissions. Few studies have investigated cardiovascular effects of air pollutants emitted from steel plants...
- Chronic disease prevalence in women and air pollution--A 30-year longitudinal cohort studyTeresa To
Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Ontario, Canada Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada Dalla Lana School of Public Health, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Electronic address
Environ Int 80:26-32. 2015..Identifying the influence of PM2.5 on prevalence of these conditions may help target interventions to reduce disease morbidity among high-risk populations...
- Obesity and the cardiovascular health effects of fine particulate air pollutionScott Weichenthal
Health Canada, Air Health Sciences Division, Ottawa, Ontario, Canada Department of Occupational and Environmental Health, University of Montreal CHUM and Cité de la santé de Laval, Quebec, Canada
Obesity (Silver Spring) 22:1580-9. 2014..This review examines evidence related to the potential impact of obesity on the cardiovascular health effects of fine particulate air pollution (PM₂.₅)...
- Statistical power in the analyses of brain weight measures in pesticide neurotoxicity testing and the relationship between brain and body weightScott Weichenthal
Health Canada, 269 Laurier Avenue West, Ottawa, ON, Canada
Regul Toxicol Pharmacol 57:235-40. 2010..Our findings suggest that caution is required when weighing the importance of statistical "significance" in studies of pesticide exposure effects on brain weight as the power to detect these differences may be low...