Research Topics
| S A TittlemierSummaryAffiliation: Health Canada Country: Canada Publications
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Detail Information
Publications
Vapour pressures, aqueous solubilities, Henry's Law constants, and octanol/water partition coefficients of a series of mixed halogenated dimethyl bipyrrolesSheryl A Tittlemier
Centre for Analytical and Environmental Chemistry, Carleton University, Ottawa, Ont, Canada K1S 5B6
Chemosphere 57:1373-81. 2004..Only slight differences in behaviour amongst HDBP congeners were predicted since substitution of a bromine for a chlorine (Cl/Br substitution) atom had less effect than H/Cl or H/Br substitution on P(o)(L,25), S(w,25), H25, and K(ow)...
Concentrations of perfluorooctanesulfonamides in Canadian total diet study composite food samples collected between 1992 and 2004Sheryl A Tittlemier
Food Research Division, Banting Research Centre 2203D, Health Canada, Ottawa, Ontario, Canada K1A 0L2
J Agric Food Chem 54:8385-9. 2006..A basic estimate of dietary exposure to perfluorooctanesulfonamides suggests that Canadians (>12 years old) are exposed to approximately 73 ng/person/day from these foods...
Dietary exposure to a group of naturally produced organohalogens (halogenated dimethyl bipyrroles) via consumption of fish and seafoodSheryl A Tittlemier
Food Research Division, Banting Research Centre 2203D, Health Canada, Ottawa, Ontario, Canada K1A 0L2
J Agric Food Chem 52:2010-5. 2004..The results of this study provide the first estimate of human exposure to naturally produced bioaccumulating organohalogens...
Analysis of veterinary drug residues in fish and shrimp composites collected during the Canadian Total Diet Study, 1993-2004S A Tittlemier
Food Research Division, Health Canada, Ottawa, ON, Canada K1A 0L2
Food Addit Contam 24:14-20. 2007..8 ng g(-1)). The results of this survey indicate that Canadians are exposed to low ng g-1 concentrations of some banned and unapproved veterinary drug residues via the consumption of certain fish and shrimp...
Naturally produced halogenated dimethyl bipyrroles bind to the aryl hydrocarbon receptor and induce cytochrome P4501A and porphyrin accumulation in chicken embryo hepatocytesSheryl A Tittlemier
Centre for Analytical and Environmental Chemistry, Carleton University, Ottawa, Ontario K1S 5B6, Canada
Environ Toxicol Chem 22:1622-31. 2003..000017. The results of this work illustrate that HDBPs act as agonist ligands for the AhR in the same manner as many anthropogenic organohalogens...
Reproductive and morphological effects of halogenated dimethyl bipyrroles on captive American kestrels (Falco sparverius)Sheryl A Tittlemier
Centre for Analytical and Environmental Chemistry, Carleton University, Ottawa, Ontario K1S 5B6, Canada
Environ Toxicol Chem 22:1497-506. 2003..Only minor histomorphological changes were detected in the hepatic tissue. The lack of serious effects suggests that HDBPs are not an acute reproductive threat to avian populations...
Dietary exposure of Canadians to perfluorinated carboxylates and perfluorooctane sulfonate via consumption of meat, fish, fast foods, and food items prepared in their packagingSheryl A Tittlemier
Food Research Division, Banting Research Centre 2203D, and Chemical Health Hazard Assessment Division, Banting Research Centre 2204D, Health Canada, Ottawa, Ontario K1A 0L2, Canada
J Agric Food Chem 55:3203-10. 2007..There was a substantial margin of exposure between the toxicological points of reference and the magnitude of dietary intake of perfluorinated compounds for Canadians >/= 12 years old...
Melamine in infant formula sold in Canada: occurrence and risk assessmentSheryl A Tittlemier
Food Research Division, Banting Research Centre 2203D, Health Canada, Ottawa, Ontario, Canada
J Agric Food Chem 57:5340-4. 2009....
Methods for the analysis of melamine and related compounds in foods: a reviewS A Tittlemier
Food Research Division, Banting Research Centre 2203D, Health Canada, Ottawa, Ontario, Canada
Food Addit Contam Part A Chem Anal Control Expo Risk Assess 27:129-45. 2010..These issues include contamination, matrix effects, and analyte instability, and their severity varies according to the method used, and matrices and analytes examined...
Vapor pressures, aqueous solubilities, and Henry's law constants of some brominated flame retardantsSheryl A Tittlemier
Centre for Analytical and Environmental Chemistry, Carleton University, Ottawa, Ontario, Canada
Environ Toxicol Chem 21:1804-10. 2002..Degradative debromination reactions that yield these congeners would mobilize them environmentally, and ultimately affect the fate and distribution of BFRs...
Fluorinated organic compounds in an eastern Arctic marine food webGregg T Tomy
Department of Fisheries and Oceans Canada, 501 University Crescent, Winnipeg, Manitoba R3T2N6, Canada
Environ Sci Technol 38:6475-81. 2004..The presence of perfluorinated compounds in seabirds and mammals provides evidence that trophic transfer is an important exposure route of these chemicals to Arctic biota...
Determination of melamine, ammeline, ammelide and cyanuric acid in infant formula purchased in Canada by liquid chromatography-tandem mass spectrometryE Braekevelt
Food Research Division, Health Canada, Ottawa, ON, Canada
Food Addit Contam Part A Chem Anal Control Expo Risk Assess 28:698-704. 2011..The total of MEL-related compounds (sum of all four analytes) in all samples was below the interim standard of 0.5 mg kg(-1) for infant formula products established by Health Canada...
Development and characterization of a solvent extraction-gas chromatographic/mass spectrometric method for the analysis of perfluorooctanesulfonamide compounds in solid matricesSheryl A Tittlemier
Food Research Division, Banting Research Centre 2203D, Health Canada, Ottawa, Ont, Canada K1A 0L2
J Chromatogr A 1066:189-95. 2005..The three compounds were found at concentrations ranging from below the MDL to 22 ng/g wet weight in fast food, fish, and Arctic marine mammal liver samples...
Examination of the bioaccumulation of halogenated dimethyl bipyrroles in an Arctic marine food web using stable nitrogen isotope analysisSheryl A Tittlemier
Centre for Analytical and Environmental Chemistry, Carleton University, Ottawa, Ontario, Canada
Environ Pollut 116:85-93. 2002..None of the four HDBP congeners in ringed seals followed the general trend of increasing concentration with trophic level, which was possibly due to an ability of the seals to metabolize HDBPs...
Multiresidue determination of quinolone and fluoroquinolone antibiotics in fish and shrimp by liquid chromatography/tandem mass spectrometryGuy Dufresne
Health Canada, Quebec Region Laboratory, Longueuil, Qu, J4K 1C7, Canada
J AOAC Int 90:604-12. 2007..The method has been evaluated and applied to the analysis of salmon, trout, and shrimp. Detectable residues were observed in 10 out of 73 samples, at concentrations ranging from 0.28 to 16 ng/g...
Direct measurement of octanol-water partition coefficients of some environmentally relevant brominated diphenyl ether congenersEric Braekevelt
Department of Fisheries and Oceans, Freshwater Institute, 501 University Cresent, Winnipeg, Manitoba, Canada R3T 2N6
Chemosphere 51:563-7. 2003..The tri- and tetrabrominated congeners are in the range of optimum bioaccumulation potential...
Polybrominated diphenyl ethers in retail fish and shellfish samples purchased from Canadian marketsSheryl A Tittlemier
Food Research Division and Division of Biostatistics and Epidemiology, Health Canada, Banting Research Centre 2203D, Ottawa, Ontario, Canada, K1A 0L2
J Agric Food Chem 52:7740-5. 2004..These concentration differences will contribute to variations in dietary exposure to PBDEs when assorted fish and shellfish items from various origins are consumed...
Radiocarbon evidence for a naturally produced, bioaccumulating halogenated organic compoundChristopher M Reddy
Department of Marine Chemistry and Geochemistry, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts 02543, USA
Environ Sci Technol 38:1992-7. 2004..However, these delta14C values for DBP-Br4Cl2 are more depleted than expected for a recently synthesized natural product. Several explanations are discussed, but additional samples..
Structure elucidation of four possible biogenic organohalogens using isotope exchange mass spectrometrySheryl A Tittlemier
Centre for Analytical and Environmental Chemistry, Carleton University, 1125 Colonel By Drive, Ottawa, Ont, Canada K1S 5B6
Chemosphere 46:511-7. 2002..The placement of the halogen atoms on the fourth compound, C10H6N2Br3Cl3 could not be unequivocally determined since the synthesized standard could not be fully characterized...
Vapor pressures of six brominated diphenyl ether congenersS A Tittlemier
Department of Chemistry, Carleton University, Ottawa, Ontario K1S 5B6, Canada
Environ Toxicol Chem 20:146-8. 2001..692 (bromine number)--1.76 (R2 = 0.953, p < 0.001). In addition, the first such data for individual PBDE congeners demonstrates that PLo would vary four orders of magnitude over environmentally relevant temperatures...
Biotransformation of N-ethyl perfluorooctanesulfonamide by rainbow trout (Onchorhynchus mykiss) liver microsomesGregg T Tomy
Department of Fisheries and Oceans, Winnipeg, Manitoba R3T 2N6, Canada
Environ Sci Technol 38:758-62. 2004....
Simultaneous determination of (fluoro)quinolone antibiotics in kidney, marine products, eggs, and muscle by enzyme-linked immunosorbent assay (ELISA)Anne-Catherine Huet
Centre d'Economie Rurale, laboratoire d'Hormonologie Animale, Rue Point du Jour 8, 6900 Marloie, Belgium
J Agric Food Chem 54:2822-7. 2006....
