Anna Francina Jackson

Summary

Affiliation: Health Canada
Country: Canada

Publications

  1. ncbi request reprint Bromodeoxyuridine (BrdU) treatment to measure hepatocellular proliferation does not mask furan-induced gene expression changes in mouse liver
    Anna Francina Webster
    Environmental Health Science and Research Bureau, Health Canada, Ottawa K1A 0K9, Canada Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa K1S 5B6, Canada Electronic address
    Toxicology 323:26-31. 2014
  2. doi request reprint Case study on the utility of hepatic global gene expression profiling in the risk assessment of the carcinogen furan
    Anna Francina Jackson
    Environmental Health Science and Research Bureau, Health Canada, Ottawa K1A 0K9, Canada Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa K1S 5B6, Canada Electronic address
    Toxicol Appl Pharmacol 274:63-77. 2014

Collaborators

Detail Information

Publications2

  1. ncbi request reprint Bromodeoxyuridine (BrdU) treatment to measure hepatocellular proliferation does not mask furan-induced gene expression changes in mouse liver
    Anna Francina Webster
    Environmental Health Science and Research Bureau, Health Canada, Ottawa K1A 0K9, Canada Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa K1S 5B6, Canada Electronic address
    Toxicology 323:26-31. 2014
    ..However, we also recommend that this type of case study be repeated for other chemicals before the use of BrdU-treated animals in omics studies becomes common practice. ..
  2. doi request reprint Case study on the utility of hepatic global gene expression profiling in the risk assessment of the carcinogen furan
    Anna Francina Jackson
    Environmental Health Science and Research Bureau, Health Canada, Ottawa K1A 0K9, Canada Department of Biology, Carleton University, 1125 Colonel By Drive, Ottawa K1S 5B6, Canada Electronic address
    Toxicol Appl Pharmacol 274:63-77. 2014
    ..In conclusion, using furan as a case study we have demonstrated the value of toxicogenomics data in elucidating dose-dependent MOA transitions and in quantitative risk assessment. ..