Xu Liang Cao

Summary

Affiliation: Health Canada
Country: Canada

Publications

  1. ncbi request reprint Occurrence of Di-(2-ethylhexyl) adipate and phthalate plasticizers in samples of meat, fish, and cheese and their packaging films
    Xu Liang Cao
    Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario, Canada K1A 0K9
    J Food Prot 77:610-20. 2014
  2. doi request reprint Di-(2-ethylhexyl) adipate in selected total diet food composite samples
    Xu Liang Cao
    Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario, Canada K1A 0K9
    J Food Prot 76:1985-8. 2013
  3. doi request reprint Headspace solid-phase microextraction with gas chromatography-mass spectrometry determination of naphthalene in the composite food samples from the 2011 Canadian total diet study in Ottawa
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Health Canada, AL 2203D, Ottawa, Ontario, Canada K1A 0K9
    J Food Prot 75:2163-71. 2012
  4. doi request reprint Bisphenol A in human placental and fetal liver tissues collected from Greater Montreal area (Quebec) during 1998-2008
    Xu Liang Cao
    Health Canada, Ottawa, Ontario, Canada K1A 0K9
    Chemosphere 89:505-11. 2012
  5. ncbi request reprint Sources of low concentrations of bisphenol A in canned beverage products
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Frederick Banting Driveway, AL 2203D, Ottawa, Ontario, Canada K1A 0K9
    J Food Prot 73:1548-51. 2010
  6. pmc Concentrations of bisphenol A in the composite food samples from the 2008 Canadian total diet study in Quebec City and dietary intake estimates
    X L Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario, Canada
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 28:791-8. 2011
  7. doi request reprint Background bisphenol A in experimental materials and its implication to low-dose in vitro study
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario, Canada
    Chemosphere 81:817-20. 2010
  8. ncbi request reprint Bisphenol a in canned food products from canadian markets
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Frederick Banting Driveway, AL 2203D, Ottawa, Ontario, Canada K1A 0K9
    J Food Prot 73:1085-9. 2010
  9. ncbi request reprint Levels of bisphenol A diglycidyl ether (BADGE) and bisphenol F diglycidyl ether (BFDGE) in canned liquid infant formula products in Canada and dietary intake estimates
    Xu Liang Cao
    Health Canada, Food Research Division, Bureau of Chemical Safety, Food Directorate, 251 Frederick Banting Driveway, AL 2203D, Ottawa, ON, Canada K1A 0K9
    J AOAC Int 92:1780-9. 2009
  10. doi request reprint Levels of bisphenol A in canned soft drink products in Canadian markets
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Frederick Banting Driveway, AL 2203D, Ottawa, Ontario, Canada
    J Agric Food Chem 57:1307-11. 2009

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Occurrence of Di-(2-ethylhexyl) adipate and phthalate plasticizers in samples of meat, fish, and cheese and their packaging films
    Xu Liang Cao
    Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario, Canada K1A 0K9
    J Food Prot 77:610-20. 2014
    ..Levels of DEHA found in most of the cheese samples from this study are above the European specific migration limit of 18 mg/kg for DEHA in food or food simulants, and levels of phthalates (i.e., DEHP) were low. ..
  2. doi request reprint Di-(2-ethylhexyl) adipate in selected total diet food composite samples
    Xu Liang Cao
    Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario, Canada K1A 0K9
    J Food Prot 76:1985-8. 2013
    ..20 μg/g). Targeted surveys should be conducted to investigate the presence of DEHA in various foods packaged with PVC films in more detail and provide updated occurrence data for accurate human exposure assessment. ..
  3. doi request reprint Headspace solid-phase microextraction with gas chromatography-mass spectrometry determination of naphthalene in the composite food samples from the 2011 Canadian total diet study in Ottawa
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Health Canada, AL 2203D, Ottawa, Ontario, Canada K1A 0K9
    J Food Prot 75:2163-71. 2012
    ..0022 ng/g for water to as high as 16 ng/g for fatty sample, with an average of 1.6 ng/g...
  4. doi request reprint Bisphenol A in human placental and fetal liver tissues collected from Greater Montreal area (Quebec) during 1998-2008
    Xu Liang Cao
    Health Canada, Ottawa, Ontario, Canada K1A 0K9
    Chemosphere 89:505-11. 2012
    ..The percentages of free BPA level relative to total BPA for all fetal liver samples varied from 12.4% to 99.1%, indicating extensive variability in the ability of the human feto-placental unit to glucuronidate BPA...
  5. ncbi request reprint Sources of low concentrations of bisphenol A in canned beverage products
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Frederick Banting Driveway, AL 2203D, Ottawa, Ontario, Canada K1A 0K9
    J Food Prot 73:1548-51. 2010
    ..054 microg/liter) but was detected in all corresponding beer samples in cans at low concentrations ranging from 0.081 to 0.54 microg/liter, indicating that migration from can coatings is likely the source of BPA in canned beer products...
  6. pmc Concentrations of bisphenol A in the composite food samples from the 2008 Canadian total diet study in Quebec City and dietary intake estimates
    X L Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario, Canada
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 28:791-8. 2011
    ..BPA intakes from 19 of the 55 samples account for more than 95% of the total dietary intakes, and most of the 19 samples were either canned or in jars. Intakes of BPA from non-canned foods are low...
  7. doi request reprint Background bisphenol A in experimental materials and its implication to low-dose in vitro study
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, Ottawa, Ontario, Canada
    Chemosphere 81:817-20. 2010
    ..35 to 19 nM) with an average of 0.83 ng mL(-1) (3.5 nM). We suggest that culture media used for low-dose BPA studies should be analysed for background BPA levels prior to use, and the medium with the lowest BPA levels should be used...
  8. ncbi request reprint Bisphenol a in canned food products from canadian markets
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Frederick Banting Driveway, AL 2203D, Ottawa, Ontario, Canada K1A 0K9
    J Food Prot 73:1085-9. 2010
    ..The mean and maximum BPA concentrations were 1.1 and 2.1 ng/g, respectively, for tomato paste products and 9.3 and 23 ng/g, respectively, for the pure tomato products...
  9. ncbi request reprint Levels of bisphenol A diglycidyl ether (BADGE) and bisphenol F diglycidyl ether (BFDGE) in canned liquid infant formula products in Canada and dietary intake estimates
    Xu Liang Cao
    Health Canada, Food Research Division, Bureau of Chemical Safety, Food Directorate, 251 Frederick Banting Driveway, AL 2203D, Ottawa, ON, Canada K1A 0K9
    J AOAC Int 92:1780-9. 2009
    ..The maximum PDI of BADGE was 22 microg/kg body weight/day for the 12-18 months old with the maximum formula intake. The maximum PDI of BFDGE was < 3.4 microg/kg body weight/day...
  10. doi request reprint Levels of bisphenol A in canned soft drink products in Canadian markets
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Frederick Banting Driveway, AL 2203D, Ottawa, Ontario, Canada
    J Agric Food Chem 57:1307-11. 2009
    ..5 microg/L) for an adult with a 60 kg body weight, well below the provisional tolerable daily intake of 25 microg/kg of body weight/day established by Health Canada...
  11. doi request reprint GC-MS analysis of bisphenol A in human placental and fetal liver samples
    Jie Zhang
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, AL 2203D, Ottawa, Ontario, Canada K1A 0K9
    J Chromatogr B Analyt Technol Biomed Life Sci 879:209-14. 2011
    ..Further work will be conducted to validate these preliminary findings...
  12. doi request reprint Levels of bisphenol A in canned liquid infant formula products in Canada and dietary intake estimates
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Frederick Banting Driveway, AL 2203D, Ottawa, Ontario, Canada K1A 0L2
    J Agric Food Chem 56:7919-24. 2008
    ..35 microg kg(-1) of body weight day(-1) for 0-1-month-old infants with the maximum formula intake, which is below the provisional tolerable daily intake for BPA established by Health Canada, 25 microg kg(-1) of body weight day(-1)...
  13. ncbi request reprint Migration of bisphenol A from can coatings to liquid infant formula during storage at room temperature
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, Ottawa, Ontario, Canada K1A 0K9
    J Food Prot 72:2571-4. 2009
    ..3 ng/g) and those analyzed in 2007 (mean, 5.8 ng/g) were not significant (P = 0.097). No obvious correlation between the product expiration date and the level of BPA migration from can coatings was observed...
  14. ncbi request reprint Baseline levels of melamine in food items sold in Canada. II. Egg, soy, vegetable, fish and shrimp products
    Sheryl A Tittlemier
    a Food Research Division, Banting Research Centre 2203D, Health Canada, Ottawa, Ontario, Canada K1A 0L2
    Food Addit Contam Part B Surveill 3:140-7. 2010
    ..hc-sc.gc.ca/fn-an/securit/chem-chim/melamine/qa-melamine-qr-eng.php#8 ). The consumption of foods containing these low levels of MEL does not constitute a health risk for consumers...
  15. doi request reprint Migration of bisphenol A from polycarbonate baby and water bottles into water under severe conditions
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Frederick Banting Driveway, AL 2203D, Ottawa, Ontario K1A 0K9, Canada
    J Agric Food Chem 56:6378-81. 2008
    ..26 to 0.90 microg cm (-2) after being heated at 70 degrees C for 6 days. The average migration rates of BPA from the PC bottles into water at 70 degrees C ranged from 1.84 to 4.83 ng cm (-2) h (-1)...
  16. ncbi request reprint Determination of benzene in soft drinks and other beverages by isotope dilution headspace gas chromatography/mass spectrometry
    Xu Liang Cao
    Food Directorate, Health Canada, Food Research Division, Bureau of Chemical Safety, Banting Building, AL 2203D, Ottawa, ON, K1A 0L2, Canada
    J AOAC Int 90:479-84. 2007
    ..The highest level of benzene, 23 microg/L, was found in a soft drink product specifically marketed to children...
  17. doi request reprint Aniline in vegetable and fruit samples from the Canadian total diet study
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, HPFB, Ottawa, Ontario, Canada K1A 0K9
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 26:808-13. 2009
    ..277 mg kg(-1). Good repeatability of the method was observed with replicate analysis of apple samples, with relative standard deviations (RSD) ranging 3.8-21% and an average of 11%...
  18. ncbi request reprint Determination of bisphenol A in water by isotope dilution headspace solid-phase microextraction and gas chromatography/mass spectrometry without derivatization
    Xu Liang Cao
    Health Canada, Food Directorate, Bureau of Chemical Safety, Food Research Division, 251 Sir Frederick Banting Dr, AL 2203D, Ottawa, Ontario, Canada K1A 0L2
    J AOAC Int 91:622-9. 2008
    ..The automated headspace SPME method developed in this work was used to investigate migration of BPA from polycarbonate bottles into water, and levels of BPA in water ranged from 1.7 to 4.1 microg/L...
  19. ncbi request reprint Dietary exposure of Canadians to perfluorinated carboxylates and perfluorooctane sulfonate via consumption of meat, fish, fast foods, and food items prepared in their packaging
    Sheryl A Tittlemier
    Food Research Division, Banting Research Centre 2203D, and Chemical Health Hazard Assessment Division, Banting Research Centre 2204D, Health Canada, Ottawa, Ontario K1A 0L2, Canada
    J Agric Food Chem 55:3203-10. 2007
    ..There was a substantial margin of exposure between the toxicological points of reference and the magnitude of dietary intake of perfluorinated compounds for Canadians >/= 12 years old...
  20. doi request reprint Bisphenol a in baby food products in glass jars with metal lids from Canadian markets
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, Ottawa, Ontario, Canada
    J Agric Food Chem 57:5345-51. 2009
    ..2 ng/g, was found in two products from brand E as well. The average BPA level in the fruit products from all brands (0.60 ng/g) is lower than those in the mixed-dish products (1.1 ng/g) and the vegetable products (1.2 ng/g)...
  21. doi request reprint Challenges and trends in the determination of selected chemical contaminants and allergens in food
    Rudolf Krska
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, Ottawa, ON, Canada
    Anal Bioanal Chem 402:139-62. 2012
    ..Both approaches are useful when gathering surveillance data to determine occurrence and background levels of both recognized and newly identified contaminants in foods in order to estimate human daily intake for health risk assessment...
  22. doi request reprint Bisphenol A activates the Nrf1/2-antioxidant response element pathway in HEK 293 cells
    Nikolai L Chepelev
    Department of Biology, and Institute of Biochemistry, Carleton University, 1125 Colonel By Drive, Ottawa, Ontario, Canada
    Chem Res Toxicol 26:498-506. 2013
    ..Our study suggests that BPA activates the Nrf1/2-ARE pathway at high (>10 μM) micromolar concentrations...
  23. ncbi request reprint Dioxins, furans and non-ortho-PCBs in Canadian total diet foods 1992-1999 and 1985-1988
    John Jake Ryan
    Bureau Chemical Safety, Health Products and Food Branch, Health Canada, Tunney s Pasture, Ottawa, Canada
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 30:491-505. 2013
    ..These estimates are lower than the 2.3 pg of TEQ currently recommended by the WHO. The main categories of foods contributing to the TEQ were animal meats and dairy products, with lesser amounts from fish and other foods...
  24. doi request reprint An isotope dilution headspace method with gas chromatography-mass spectrometry for determination of propylene oxide in food
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, AL 2203D, Ottawa, Ontario K1A 0K9, Canada
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 26:482-6. 2009
    ..This confirms that it is very unlikely to find propylene oxide in foods as consumed due to its volatility and reaction with water...
  25. ncbi request reprint Baseline levels of melamine in food items sold in Canada. I. Dairy products and soy-based dairy replacement products
    Sheryl A Tittlemier
    a Food Research Division, Banting Research Centre 2203D, Health Canada, Ottawa, Ontario, Canada, K1A 0L2
    Food Addit Contam Part B Surveill 3:135-9. 2010
    ..5 mg/kg interim standard for melamine in products containing milk and milk-derived ingredients established by Health Canada. The consumption of foods containing these low levels of MEL does not constitute a health risk for consumers...
  26. doi request reprint Cohort profile: the maternal-infant research on environmental chemicals research platform
    Tye E Arbuckle
    Population Studies Division, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa
    Paediatr Perinat Epidemiol 27:415-25. 2013
    ....
  27. ncbi request reprint Determination of phthalates and adipate in bottled water by headspace solid-phase microextraction and gas chromatography/mass spectrometry
    Xu Liang Cao
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Frederick Banting Driveway, AL 2203D, Ottawa, Ontario K1A 0L2, Canada
    J Chromatogr A 1178:231-8. 2008
    ..DMP, DHP, BBP, DEHA and DOP were not detected in any samples. Concentrations of the other phthalates were low (around sub-ppb) except for DBP in the water from a polycarbonate bottle at 1.72 microg L(-1)...
  28. ncbi request reprint The Canadian total diet study design: 1992-1999
    Robert Dabeka
    Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, ON, Canada
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 30:477-90. 2013
    ....
  29. ncbi request reprint Survey of bisphenol A in bottled water products in Canada
    Xu Liang Cao
    a Food Research Division, Bureau of Chemical Safety, Food Directorate, Health Canada, 251 Sir Frederick Banting Driveway, AL 2203D, Ottawa, Ontario, Canada K1A 0K9
    Food Addit Contam Part B Surveill 1:161-4. 2008
    ..g. under the sun) during storage and/or transportation for extended periods of time. ..
  30. ncbi request reprint Comparison of vehicle exhaust emissions from modified diesel fuels
    Jiping Zhu
    Chemistry Research Division, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada
    J Air Waste Manag Assoc 53:67-76. 2003
    ..Reductions in nitro-PAH emissions have been observed in both the cetane-enhanced and oxygenated fuels. This further demonstrates the benefits of using a cetane enhancer and the oxygenated fuel component...