- Nonadditive effects of PAHs on Early Vertebrate Development: mechanisms and implications for risk assessmentSonya M Billiard
Health Canada, Health Products and Food Branch, Bureau of Chemical Safety, Ottawa, Ontario K1A0L2, Canada
Toxicol Sci 105:5-23. 2008..Throughout, we place particular emphasis on research on the early life stages of fish, which has proven to be a sensitive and rapid developmental model to elucidate effects of hydrocarbon mixtures...
- Binding of polycyclic aromatic hydrocarbons (PAHs) to teleost aryl hydrocarbon receptors (AHRs)Sonya M Billiard
Department of Biology, Queen s University, ON, Kingston, Canada
Comp Biochem Physiol B Biochem Mol Biol 133:55-68. 2002..If PAH toxicity is receptor-mediated and predicted by induction potencies, we will have a powerful mechanistic-based tool for rapidly assessing the risk of toxicity to fish of PAH from any source...
- The role of the aryl hydrocarbon receptor pathway in mediating synergistic developmental toxicity of polycyclic aromatic hydrocarbons to zebrafishSonya M Billiard
Nicholas School of the Environment and Integrated Toxicology Program, Duke University, Durham, North Carolina 27708 0328, USA
Toxicol Sci 92:526-36. 2006..Identifying the pathways involved in PAH toxicity will provide for more robust, mechanistic-based tools for risk assessment of single compounds and complex environmental mixtures...