Jeff S Healey

Summary

Country: Canada

Publications

  1. doi request reprint Pacemaker-detected atrial fibrillation in patients with pacemakers: prevalence, predictors, and current use of oral anticoagulation
    Jeff S Healey
    Population Health Research Institute, Hamilton, Ontario, Canada
    Can J Cardiol 29:224-8. 2013
  2. doi request reprint Cardioverter defibrillator implantation without induction of ventricular fibrillation: a single-blind, non-inferiority, randomised controlled trial (SIMPLE)
    Jeff S Healey
    Population Health Research Institute, McMaster University, Hamilton, ON, Canada Electronic address
    Lancet 385:785-91. 2015
  3. pmc Development and feasibility testing of decision support for patients who are candidates for a prophylactic implantable defibrillator: a study protocol for a pilot randomized controlled trial
    Sandra L Carroll
    School of Nursing, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada
    Trials 14:346. 2013
  4. doi request reprint Periprocedural management of oral anticoagulation in patients with atrial fibrillation: approach in the era of new oral anticoagulants
    Jeff S Healey
    Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
    Can J Cardiol 29:S54-9. 2013
  5. doi request reprint A randomized-controlled pilot study comparing ICD implantation with and without intraoperative defibrillation testing in patients with heart failure and severe left ventricular dysfunction: a substudy of the RAFT trial
    Jeff S Healey
    Population Health Research Institute, Barton St East, Hamilton, Ontario, Canada
    J Cardiovasc Electrophysiol 23:1313-6. 2012
  6. doi request reprint Relevance of electrical remodeling in human atrial fibrillation: results of the Asymptomatic Atrial Fibrillation and Stroke Evaluation in Pacemaker Patients and the Atrial Fibrillation Reduction Atrial Pacing Trial mechanisms of atrial fibrillation study
    Jeff S Healey
    Population Health Research Institute, McMaster University, Hamilton, Canada
    Circ Arrhythm Electrophysiol 5:626-31. 2012
  7. doi request reprint The rationale and design of the Shockless IMPLant Evaluation (SIMPLE) trial: a randomized, controlled trial of defibrillation testing at the time of defibrillator implantation
    Jeff S Healey
    Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
    Am Heart J 164:146-52. 2012
  8. doi request reprint Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) randomized trial
    Jeff S Healey
    Population Health Research Institute, McMaster University, Hamilton, Canada
    Circulation 126:343-8. 2012
  9. doi request reprint Canadian Cardiovascular Society/Canadian Anesthesiologists' Society/Canadian Heart Rhythm Society joint position statement on the perioperative management of patients with implanted pacemakers, defibrillators, and neurostimulating devices
    Jeff S Healey
    Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
    Can J Cardiol 28:141-51. 2012
  10. doi request reprint Does catheter ablation for atrial fibrillation increase or reduce neurological insult?
    Jeff S Healey
    Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
    Curr Opin Cardiol 27:36-40. 2012

Detail Information

Publications49

  1. doi request reprint Pacemaker-detected atrial fibrillation in patients with pacemakers: prevalence, predictors, and current use of oral anticoagulation
    Jeff S Healey
    Population Health Research Institute, Hamilton, Ontario, Canada
    Can J Cardiol 29:224-8. 2013
    ..This study sought to determine the prevalence and predictors of pacemaker-detected AF and to document current oral anticoagulant use...
  2. doi request reprint Cardioverter defibrillator implantation without induction of ventricular fibrillation: a single-blind, non-inferiority, randomised controlled trial (SIMPLE)
    Jeff S Healey
    Population Health Research Institute, McMaster University, Hamilton, ON, Canada Electronic address
    Lancet 385:785-91. 2015
    ..We aimed to compare the efficacy and safety of ICD implantation without defibrillation testing versus the standard of ICD implantation with defibrillation testing...
  3. pmc Development and feasibility testing of decision support for patients who are candidates for a prophylactic implantable defibrillator: a study protocol for a pilot randomized controlled trial
    Sandra L Carroll
    School of Nursing, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada
    Trials 14:346. 2013
    ..The objectives of this research are: 1) develop a decision aid, 2) evaluate the decision aid, and 3) determine the feasibility of conducting a trial...
  4. doi request reprint Periprocedural management of oral anticoagulation in patients with atrial fibrillation: approach in the era of new oral anticoagulants
    Jeff S Healey
    Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
    Can J Cardiol 29:S54-9. 2013
    ..Physicians and surgeons who treat patients with atrial fibrillation must be aware of these changes and understand how to deal with the new challenges they may encounter. ..
  5. doi request reprint A randomized-controlled pilot study comparing ICD implantation with and without intraoperative defibrillation testing in patients with heart failure and severe left ventricular dysfunction: a substudy of the RAFT trial
    Jeff S Healey
    Population Health Research Institute, Barton St East, Hamilton, Ontario, Canada
    J Cardiovasc Electrophysiol 23:1313-6. 2012
    ..The need to perform defibrillation testing (DT) at the time of implantable cardioverter defibrillator (ICD) insertion is controversial. In the absence of randomized trials, some regions now perform more than half of ICD implants without DT...
  6. doi request reprint Relevance of electrical remodeling in human atrial fibrillation: results of the Asymptomatic Atrial Fibrillation and Stroke Evaluation in Pacemaker Patients and the Atrial Fibrillation Reduction Atrial Pacing Trial mechanisms of atrial fibrillation study
    Jeff S Healey
    Population Health Research Institute, McMaster University, Hamilton, Canada
    Circ Arrhythm Electrophysiol 5:626-31. 2012
    ..In animal models of atrial fibrillation (AF), changes in atrial electrophysiological properties are associated with the development of AF. Their relevance to human AF is unclear...
  7. doi request reprint The rationale and design of the Shockless IMPLant Evaluation (SIMPLE) trial: a randomized, controlled trial of defibrillation testing at the time of defibrillator implantation
    Jeff S Healey
    Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
    Am Heart J 164:146-52. 2012
    ..5-year mean follow-up will provide sufficient statistical power to demonstrate noninferiority. The study is being performed at approximately 90 centers in Canada, Europe, Israel, and Asia Pacific with final results expected in 2013...
  8. doi request reprint Periprocedural bleeding and thromboembolic events with dabigatran compared with warfarin: results from the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) randomized trial
    Jeff S Healey
    Population Health Research Institute, McMaster University, Hamilton, Canada
    Circulation 126:343-8. 2012
    ..Dabigatran reduces ischemic stroke in comparison with warfarin; however, given the lack of antidote, there is concern that it might increase bleeding when surgery or invasive procedures are required...
  9. doi request reprint Canadian Cardiovascular Society/Canadian Anesthesiologists' Society/Canadian Heart Rhythm Society joint position statement on the perioperative management of patients with implanted pacemakers, defibrillators, and neurostimulating devices
    Jeff S Healey
    Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
    Can J Cardiol 28:141-51. 2012
    ..It reviews the relative merits of intraoperative magnet use vs reprogramming of devices and gives examples of situations where one or the other approach is preferable...
  10. doi request reprint Does catheter ablation for atrial fibrillation increase or reduce neurological insult?
    Jeff S Healey
    Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
    Curr Opin Cardiol 27:36-40. 2012
    ..This article will review the periprocedural and long-term risk of stroke and other adverse neurological outcomes in patients having catheter ablation of atrial fibrillation...
  11. doi request reprint Society position statement : Canadian Cardiovascular Society/Canadian Anesthesiologists' Society/Canadian Heart Rhythm Society joint position statement on the perioperative management of patients with implanted pacemakers, defibrillators, and neurostimula
    Jeff S Healey
    Population Health Research Institute, McMaster University, Room C3 121, David Braley CVSRI, 237 Barton St East, Hamilton, ON, L8L 2X2, Canada
    Can J Anaesth 59:394-407. 2012
    ....
  12. doi request reprint Canadian Cardiovascular Society atrial fibrillation guidelines 2010: etiology and initial investigations
    Jeff S Healey
    Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada
    Can J Cardiol 27:31-7. 2011
    ..Additional investigations may then be undertaken, with the decision guided by the initial evaluation. A comprehensive and systematic initial evaluation forms the foundation for a patient-specific plan for the management of AF...
  13. ncbi request reprint Cardiac resynchronization therapy in patients with permanent atrial fibrillation: results from the Resynchronization for Ambulatory Heart Failure Trial (RAFT)
    Jeff S Healey
    Population Health Research Institute, Hamilton, Ontario, Canada
    Circ Heart Fail 5:566-70. 2012
    ..Cardiac resynchronization (CRT) prolongs survival in patients with systolic heart failure and QRS prolongation. However, most trials excluded patients with permanent atrial fibrillation...
  14. doi request reprint Irbesartan in patients with atrial fibrillation
    Salim Yusuf
    Population Health Research Institute, McMaster University, Hamilton, ON, Canada
    N Engl J Med 364:928-38. 2011
    ..The risk of cardiovascular events among patients with atrial fibrillation is high. We evaluated whether irbesartan, an angiotensin-receptor blocker, would reduce this risk...
  15. doi request reprint Variations in cause and management of atrial fibrillation in a prospective registry of 15,400 emergency department patients in 46 countries: the RE-LY Atrial Fibrillation Registry
    Jonas Oldgren
    Uppsala Clinical Research Center and Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden J O, L W Population Health Research Institute, Hamilton, Ontario, Canada J S H, C A M, A G, J N, S J C, S Y Jefferson Medical College, Wynnewood, PA, and Cardiovascular Research Foundation, New York, NY M E Department of Medicine, University of Cape Town, Cape Town, South Africa P C Instituto Dante Pazzanesse de Cardiologia, Sao Paulo, Brazil A A St John s Medical College, Bangalore, India P P, A S Cardiovascular Institute and Fuwai Hospital, Beijing, China J Z, L L University Hospital Motol, Prague, Czech Republic P J Eduardo Mondlane University, Maputo, Mozambique A D Boehringer Ingelheim, Ridgefield, CT P A R Semmelweis University, Budapest, Hungary K K Thoraxcenter, University of Groningen, University Medical Center Groningen
    Circulation 129:1568-76. 2014
    ..Atrial fibrillation (AF) is the most common sustained arrhythmia; however, little is known about patients in a primary care setting from high-, middle-, and low-income countries...
  16. doi request reprint Pacemaker or defibrillator surgery without interruption of anticoagulation
    David H Birnie
    University of Ottawa Heart Institute, Ottawa, ON, Canada
    N Engl J Med 368:2084-93. 2013
    ..There have been few results from clinical trials to support the safety and efficacy of this approach...
  17. ncbi request reprint Prevention of atrial fibrillation with angiotensin-converting enzyme inhibitors and angiotensin receptor blockers: a meta-analysis
    Jeff S Healey
    Population Health Research Institute, McMaster University, and Hamilton Health Sciences, Hamilton, Ontario, Canada
    J Am Coll Cardiol 45:1832-9. 2005
    ....
  18. doi request reprint Risk of bleeding with 2 doses of dabigatran compared with warfarin in older and younger patients with atrial fibrillation: an analysis of the randomized evaluation of long-term anticoagulant therapy (RE-LY) trial
    John W Eikelboom
    Population Health Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada
    Circulation 123:2363-72. 2011
    ..The purpose of this study was to compare their risks of bleeding in the Randomized Evaluation of Long-Term Anticoagulant Therapy (RE-LY) trial...
  19. doi request reprint Safety and efficacy of dabigatran compared with warfarin for patients undergoing radiofrequency catheter ablation of atrial fibrillation: a meta-analysis
    Mohammed Shurrab
    Arrhythmia Services, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada Electronic address
    Can J Cardiol 29:1203-10. 2013
    ..We conducted a meta-analysis of the periprocedural use of dabigatran vs warfarin (with or without heparin bridging)...
  20. doi request reprint Canadian Registry of ICD Implant Testing procedures (CREDIT): current practice, risks, and costs of intraoperative defibrillation testing
    Jeff S Healey
    The Population Health Research Institute, McMaster University, Hamilton, Canada
    J Cardiovasc Electrophysiol 21:177-82. 2010
    ..There is uncertainty about the proper role of defibrillation testing (DT) at the time of implantable cardioverter defibrillator (ICD) insertion...
  21. doi request reprint Postoperative low-molecular-weight heparin bridging is associated with an increase in wound hematoma following surgery for pacemakers and implantable defibrillators
    Marlene Robinson
    Department of Medicine, McMaster University, 237 Barton Street East, Hamilton, Ontario, Canada
    Pacing Clin Electrophysiol 32:378-82. 2009
    ..Low-molecular-weight heparin (LMWH) is often used; however, wound hematoma is a common complication...
  22. doi request reprint Temporal relationship between subclinical atrial fibrillation and embolic events
    Michela Brambatti
    From the Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada M B, S J C, C A M, J N, M H, W Q D, J S H Clinica di Cardiologia, Universita Politecnica delle Marche, Ancona, Italy M B, A C Medical University of South Carolina, Charleston M R G Cardiology Department, Loreto Mare, Napoli, Italy C M Queen Mary Hospital, Department of Medicine, University of Hong Kong, Hong Kong, China C P L University of Groningen, University Medical Center Groningen, Groningen, Netherlands I C V G J W Goethe University, Frankfurt, Germany S H H St Jude Medical, Sylmar, CA, and Zaventem, Belgium M C Clinique du Sud Luxembourg, Arlon, Belgium G H M and Evangelical Hospital Bielefeld, Department of Medicine, Division of Cardiology, Bielefeld, Germany C W I
    Circulation 129:2094-9. 2014
    ..Among patients with implantable pacemakers and defibrillators, subclinical atrial fibrillation (SCAF) is associated with an increased risk of stroke; however, there is limited understanding of their temporal relationship...
  23. doi request reprint Left Atrial Appendage Occlusion Study II (LAAOS II)
    Richard P Whitlock
    Population Health Research Institute, Hamilton Health Sciences McMaster University, Hamilton, Ontario, Canada Electronic address
    Can J Cardiol 29:1443-7. 2013
    ..The Left Atrial Appendage Occlusion Study II (LAAOS II) explored the feasibility of a definitive trial of LAA occlusion for stroke prevention in AF...
  24. ncbi request reprint Left Atrial Appendage Occlusion Study (LAAOS): results of a randomized controlled pilot study of left atrial appendage occlusion during coronary bypass surgery in patients at risk for stroke
    Jeff S Healey
    McMaster University, Hamilton, Ontario, Canada
    Am Heart J 150:288-93. 2005
    ..This pilot study assessed the safety and efficacy of left atrial appendage (LAA) occlusion, performed at the time of coronary artery bypass grafting (CABG)...
  25. ncbi request reprint The effect of atrial-based pacing on exercise capacity as measured by the 6-minute walk test: a substudy of the Canadian Trial of Physiological Pacing (CTOPP)
    Adrian Baranchuk
    Queen s University, Kingston, Ontario, Canada
    Heart Rhythm 4:1024-8. 2007
    ....
  26. doi request reprint Subclinical atrial fibrillation and the risk of stroke
    Jeff S Healey
    Population Health Research Institute, McMaster University, Hamilton, ON, Canada
    N Engl J Med 366:120-9. 2012
    ..We evaluated whether subclinical episodes of rapid atrial rate detected by implanted devices were associated with an increased risk of ischemic stroke in patients who did not have other evidence of atrial fibrillation...
  27. doi request reprint Atrial overdrive pacing in sleep apnoea: a meta-analysis
    Adrian Baranchuk
    Cardiac Electrophysiology and Pacing, Kingston General Hospital, Queen s University, FAPC 3, 76 Stuart Street, Kingston, ON, Canada
    Europace 11:1037-40. 2009
    ....
  28. doi request reprint Focused 2012 update of the Canadian Cardiovascular Society atrial fibrillation guidelines: recommendations for stroke prevention and rate/rhythm control
    Allan C Skanes
    Arrhythmia Service, University Hospital, University of Western Ontario, London, Ontario, Canada
    Can J Cardiol 28:125-36. 2012
    ..This report presents the details of the new recommendations, along with the background and rationale...
  29. doi request reprint Predictors of atrio-ventricular conduction disease, long-term outcomes in patients with myotonic dystrophy types I and II
    Andrew H Ha
    McMaster University, Hamilton, Ontario, Canada
    Pacing Clin Electrophysiol 35:1262-9. 2012
    ..Patients with myotonic dystrophy (DM) have an annual mortality of approximately 3.5%, one-third of which is sudden cardiac death. The predictors of cardiac conduction disease in these patients are incompletely defined...
  30. doi request reprint Risks and benefits of oral anticoagulation compared with clopidogrel plus aspirin in patients with atrial fibrillation according to stroke risk: the atrial fibrillation clopidogrel trial with irbesartan for prevention of vascular events (ACTIVE-W)
    Jeff S Healey
    Population Health Research Institute, McMaster University, 237 Barton St E, Hamilton, Ontario, Canada
    Stroke 39:1482-6. 2008
    ..However, because OAC carries important bleeding complications, risk stratification schemes have been devised to identify patients for whom the absolute benefits of OAC exceed its risks...
  31. pmc Stroke prevention in patients with atrial fibrillation: the diagnosis and management of hypertension by specialists
    Jeff S Healey
    McMaster University, Hamilton, Ontario
    Can J Cardiol 22:485-8. 2006
    ..Hypertension is common in patients with atrial fibrillation (AF) and is an important cause of stroke...
  32. doi request reprint Relationship between degree of left ventricular dysfunction, symptom status, and risk of embolic events in patients with atrial fibrillation and heart failure
    Roopinder K Sandhu
    From the Division of Cardiology, Mazankowski Alberta Heart Institute, University of Alberta, Edmonton, Canada R K S Division of Cardiac Electrophysiology, J W Goethe University, Frankfurt, Germany S H H Division of Cardiology, Brigham and Women s Hospital, Harvard University, Boston, MA M A P Division of Neurology R G H, Division of Cardiology S Y, S J C, J S H, Population Health Research Institute F Y, McMaster University, Hamilton, ON, Canada The Canadian VIGOUR Center, Edmonton, Alberta, Canada F A M and Division of General Internal Medicine, University of Alberta, Edmonton, Canada F A M
    Stroke 46:667-72. 2015
    ..Limited data exists regarding the relationship between left ventricular systolic dysfunction (LVSD) and heart failure (HF) symptoms and embolic risk among patients with atrial fibrillation...
  33. doi request reprint Risk of ischaemic stroke according to pattern of atrial fibrillation: analysis of 6563 aspirin-treated patients in ACTIVE-A and AVERROES
    Thomas Vanassche
    Population Health Research Institute, McMaster University and Hamilton Health Sciences, 237 Barton St E, Hamilton, ON, Canada L8L 2X2
    Eur Heart J 36:281-7a. 2015
    ..However, previous studies have not consistently shown AF pattern to predict stroke but have been hampered by methodological shortcomings of low power, variable event ascertainment, and variable anticoagulant use...
  34. doi request reprint Implantable cardioverter-defibrillator shock prevention does not reduce mortality: a systemic review
    Andrew H Ha
    McMaster University, Hamilton, Ontario, Canada
    Heart Rhythm 9:2068-74. 2012
    ..Antiarrhythmic medications, catheter ablation, and enhanced ICD programming all may reduce ICD shocks, but whether shock reduction decreases mortality is unknown...
  35. doi request reprint 2014 focused update of the Canadian Cardiovascular Society Guidelines for the management of atrial fibrillation
    Atul Verma
    Southlake Regional Health Centre, University of Toronto, Newmarket, Ontario, Canada Electronic address
    Can J Cardiol 30:1114-30. 2014
    ..In addition, a complete set of presently applicable recommendations, those that have been updated and those that remain in force from previous guideline versions, is provided in the Supplementary Material. ..
  36. doi request reprint The evolving role of stroke prediction schemes for patients with atrial fibrillation
    Andrew Ha
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Can J Cardiol 29:1173-80. 2013
    ..However, the nature and role of such schemes is now adapting to the current era of novel oral anticoagulant agents. ..
  37. doi request reprint The burden of atrial fibrillation on the hospital sector in Canada
    Daria J O'Reilly
    Programs for Assessment of Technology in Health PATH Research Institute, St Joseph s Healthcare Hamilton, Hamilton, Ontario, Canada
    Can J Cardiol 29:229-35. 2013
    ..The purpose of this study was to estimate the cost of AF related to hospital-based care in Canada...
  38. doi request reprint Interventions for preventing post-operative atrial fibrillation in patients undergoing heart surgery
    Kyle A Arsenault
    Department of Surgery, McMaster University, Hamilton, Canada
    Cochrane Database Syst Rev 1:CD003611. 2013
    ..We conducted an update to a 2004 Cochrane systematic review and meta-analysis of the literature to gain a better understanding of the effectiveness of these interventions...
  39. ncbi request reprint Right ventricular apical pacing: a necessary evil?
    Jeff S Healey
    McMaster University, Hamilton, Canada
    Curr Opin Cardiol 22:33-8. 2007
    ..Clinical trial evidence suggests that traditional right ventricular apical pacing may be harmful. This review summarizes the existing evidence and outlines the major avenues of ongoing research in this field...
  40. doi request reprint New pharmacotherapy for stroke prevention in atrial fibrillation: update 2010
    Luciana Armaganijan
    Department of Medicine, Cardiology Division, Arrhythmia Service, McMaster University, HHSC, David Braley CVSRI, Hamilton, Ontario, Canada
    Adv Ther 26:1058-71. 2009
    ..This review focuses on new antithrombotic therapies for stroke prevention in patients with AF...
  41. doi request reprint Comparative effectiveness of catheter ablation strategies for rhythm control in patients with atrial fibrillation: a meta-analysis
    Nazila Assasi
    Programs for Assessment of Technology in Health Research Institute, McMaster University, Hamilton, ON, Canada L8P 1H1
    J Interv Card Electrophysiol 35:259-75. 2012
    ..Ablation of additional sites has been used to increase the efficacy of ablation procedures in restoring and maintaining normal sinus rhythm...
  42. ncbi request reprint Role of the renin-angiotensin-aldosterone system in atrial fibrillation and cardiac remodeling
    Jeff S Healey
    McMaster University, Hamilton, Ontario, Canada
    Curr Opin Cardiol 20:31-7. 2005
    ..It then explores the possible mechanisms for this effect based on current animal models and limited human study...
  43. doi request reprint Atrial Premature Beats Predict Atrial Fibrillation in Cryptogenic Stroke: Results From the EMBRACE Trial
    David J Gladstone
    From the Division of Neurology D J G, Department of Medicine D J G, P D, M S, M M, and Dalla Lana School of Public Health K E T, University of Toronto, Toronto, Ontario, Canada University of Toronto Stroke Program, Toronto, Ontario, Canada D J G Division of Neurology, Department of Medicine, and the Hurvitz Brain Sciences Program, Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, Toronto, Ontario, Canada D J G Heart and Stroke Foundation Canadian Partnership for Stroke Recovery, Toronto, Ontario, Canada D J G Applied Health Research Centre AHRC, Li Ka Shing Knowledge Institute of St Michael s Hospital, Toronto, Ontario, Canada M M, V P, K E T and Population Health Research Institute, McMaster University, Hamilton, Ontario, Canada J S H
    Stroke 46:936-41. 2015
    ..Many ischemic strokes or transient ischemic attacks are labeled cryptogenic but may have undetected atrial fibrillation (AF). We sought to identify those most likely to have subclinical AF...
  44. doi request reprint VDD vs DDD pacemakers: a meta-analysis
    Mohammed Shurrab
    Arrhythmia Services, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Can J Cardiol 30:1385-91. 2014
    ..Dual-chamber (DDD) and VDD pacing are recognized alternatives for patients with advanced atrioventricular (AV) conduction abnormalities and spared sinus node function. The comparative data between these 2 modes are limited...
  45. doi request reprint Evolution of clinical diagnosis in patients presenting with unexplained cardiac arrest or syncope due to polymorphic ventricular tachycardia
    Maria Vittoria Matassini
    Population Health Research Institute, McMaster University, Hamilton, Canada Polytechnic University of Marche, Ancona, Italy
    Heart Rhythm 11:274-81. 2014
    ..However, evolution of clinical phenotype, identification of new disease-causing mutations, and description of new syndromes may revise the diagnosis...
  46. doi request reprint Evaluation of genes encoding for the transient outward current (Ito) identifies the KCND2 gene as a cause of J-wave syndrome associated with sudden cardiac death
    Mark J Perrin
    From the Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa M J P, A A, S G, F A Z, P D, n o, S U, D B Population Health Research Institute, McMaster University, Hamilton, ON J S H Division of Cardiology, Department of Medicine, University of British Columbia, Vancouver, BC S S, A D K Division of Cardiology, Department of Medicine, Dalhousie University, Halifax, NS M G Division of Cardiology, Department of Medicine, Laval University, Quebec, QC J C Division of Cardiology, Department of Medicine, Queens University, Kingston C S Division of Cardiology, St Michael s Hospital, University of Toronto, Toronto, ON, Canada K A Department of Genetics, University of Groningen, University Medical Center, Groningen, the Netherlands M P v d B, J P v T Division of Cardiology, Toronto General Hospital, University of Toronto, Toronto, ON, Canada V C
    Circ Cardiovasc Genet 7:782-9. 2014
    ..This study aimed to determine the frequency of genetic mutations in genes encoding the I(to) in patients with J waves on ECG...
  47. doi request reprint Bidirectional ventricular tachycardia secondary to subacute myocarditis
    Ashley Chin
    McMaster University, Departments of Medicine and Pathology and Molecular Medicine, Hamilton, Ontario, Canada
    Can J Cardiol 29:254.e13-4. 2013
    ..The patient had an episode of bidirectional ventricular tachycardia during the acute admission. Subacute myocarditis should be added to the limited differential diagnosis of bidirectional ventricular tachycardia...
  48. ncbi request reprint Atrial fibrillation: hypertension as a causative agent, risk factor for complications, and potential therapeutic target
    Jeff S Healey
    McMaster University, Hamilton, Ontario, Canada
    Am J Cardiol 91:9G-14G. 2003
    ..Specific pharmacotherapy could potentially play a major role in the primary and secondary prevention of atrial fibrillation and its complications...
  49. ncbi request reprint Cost-effectiveness of physiologic pacing: results of the Canadian Health Economic Assessment of Physiologic Pacing
    Bernie J O'Brien
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Heart Rhythm 2:270-5. 2005
    ..The purpose of this study was to determine the cost-effectiveness of physiologic pacemakers...