Y Fradet

Summary

Country: Canada

Publications

  1. ncbi request reprint Dietary fat and prostate cancer progression and survival
    Y Fradet
    Laval University, Quebec, Que, Canada
    Eur Urol 35:388-91. 1999
  2. doi request reprint Biomarkers in prostate cancer diagnosis and prognosis: beyond prostate-specific antigen
    Yves Fradet
    Department of Surgery, Faculty of Medicine, Laval University, Quebec, Quebec, Canada
    Curr Opin Urol 19:243-6. 2009
  3. pmc Should Canadians be offered systematic prostate cancer screening? Yes
    Yves Fradet
    Laval University, Quebec
    Can Fam Physician 53:989-92, 994-7. 2007
  4. ncbi request reprint Can biological markers predict recurrence and progression of superficial bladder cancer?
    Y Fradet
    Department of Oncology, Laval University Cancer Research Center, Quebec, Canada
    Curr Opin Urol 10:441-5. 2000
  5. ncbi request reprint Cancer-testis antigen expression in bladder cancer
    Yves Fradet
    Centre de recherche en cancérologie de l Université Laval, CHUQ L Hôtel Dieu de Québec, Quebec, Canada
    Prog Urol 16:421-8. 2006
  6. ncbi request reprint Dietary energy and nutrients in relation to preclinical prostate cancer
    F Meyer
    Department of Social and Preventive Medicine, Laval University, QC, Canada
    Nutr Cancer 29:120-6. 1997
  7. ncbi request reprint Quebec prostate cancer mortality dropped in 1996
    F Meyer
    Department of Social and Preventive Medicine, Faculty of Medicine, Laval University, Sainte Foy, Que
    Cancer Prev Control 2:163-6. 1998
  8. ncbi request reprint Duration of neoadjuvant androgen deprivation therapy before radical prostatectomy and disease-free survival in men with prostate cancer
    F Meyer
    Cancer Research Center and Faculty of Medicine, Laval University, Quebec, Canada
    Urology 58:71-7. 2001
  9. ncbi request reprint Expression of p21 predicts PSA failure in locally advanced prostate cancer treated by prostatectomy
    L Lacombe
    Urology Service, Department of Surgery, Laval University, , Quebec G1R 2J6, Canada
    Int J Cancer 95:135-9. 2001
  10. ncbi request reprint Lifetime occupational physical activity and incidental prostate cancer (Canada)
    I Bairati
    Department of Social and Preventive Medicine, Laval University, Quebec City, Canada
    Cancer Causes Control 11:759-64. 2000

Collaborators

Detail Information

Publications40

  1. ncbi request reprint Dietary fat and prostate cancer progression and survival
    Y Fradet
    Laval University, Quebec, Que, Canada
    Eur Urol 35:388-91. 1999
    ..We studied the association between dietary fat intake and prostate cancer survival...
  2. doi request reprint Biomarkers in prostate cancer diagnosis and prognosis: beyond prostate-specific antigen
    Yves Fradet
    Department of Surgery, Faculty of Medicine, Laval University, Quebec, Quebec, Canada
    Curr Opin Urol 19:243-6. 2009
    ..To review the most recent advances in genetic testing for prostate cancer risk and of new molecular diagnostic assays to improve diagnostic accuracy and treatment decision beyond prostate-specific antigen (PSA) testing...
  3. pmc Should Canadians be offered systematic prostate cancer screening? Yes
    Yves Fradet
    Laval University, Quebec
    Can Fam Physician 53:989-92, 994-7. 2007
  4. ncbi request reprint Can biological markers predict recurrence and progression of superficial bladder cancer?
    Y Fradet
    Department of Oncology, Laval University Cancer Research Center, Quebec, Canada
    Curr Opin Urol 10:441-5. 2000
    ..Molecular fingerprints of superficial tumors with distinct clinical behavior are being rapidly unravelled. Large-scale clinical studies are urgently needed to provide supportive evidence for their incorporation in clinical management...
  5. ncbi request reprint Cancer-testis antigen expression in bladder cancer
    Yves Fradet
    Centre de recherche en cancérologie de l Université Laval, CHUQ L Hôtel Dieu de Québec, Quebec, Canada
    Prog Urol 16:421-8. 2006
  6. ncbi request reprint Dietary energy and nutrients in relation to preclinical prostate cancer
    F Meyer
    Department of Social and Preventive Medicine, Laval University, QC, Canada
    Nutr Cancer 29:120-6. 1997
    ..This study provides some evidence that total energy intake is related to preclinical prostate cancer and suggests that diet could be involved earlier than thought in the occurrence of prostate cancer...
  7. ncbi request reprint Quebec prostate cancer mortality dropped in 1996
    F Meyer
    Department of Social and Preventive Medicine, Faculty of Medicine, Laval University, Sainte Foy, Que
    Cancer Prev Control 2:163-6. 1998
    ..To monitor incidence and mortality rates of prostate cancer in the province of Quebec...
  8. ncbi request reprint Duration of neoadjuvant androgen deprivation therapy before radical prostatectomy and disease-free survival in men with prostate cancer
    F Meyer
    Cancer Research Center and Faculty of Medicine, Laval University, Quebec, Canada
    Urology 58:71-7. 2001
    ..No association was observed for ADT of </=92 days. These results suggest that neoadjuvant ADT before RP has a real, delayed, and persistent effect on disease-free survival, if and only if ADT is prolonged beyond 3 months...
  9. ncbi request reprint Expression of p21 predicts PSA failure in locally advanced prostate cancer treated by prostatectomy
    L Lacombe
    Urology Service, Department of Surgery, Laval University, , Quebec G1R 2J6, Canada
    Int J Cancer 95:135-9. 2001
    ..This tumor marker may help clinicians identify patients who may require adjuvant treatment strategies following radical prostatectomy...
  10. ncbi request reprint Lifetime occupational physical activity and incidental prostate cancer (Canada)
    I Bairati
    Department of Social and Preventive Medicine, Laval University, Quebec City, Canada
    Cancer Causes Control 11:759-64. 2000
    ....
  11. pmc [International Prostate Symptom Scale. Evaluation of the usefulness of a French version]
    J Moisan
    Faculté de pharmacie de l Université Laval, Que
    Can Fam Physician 46:1772-6. 2000
    ....
  12. ncbi request reprint Insulin-like growth factor binding protein 2: an androgen-dependent predictor of prostate cancer survival
    Brant A Inman
    Division of Urology, Laval University, CRHDQ, 11 Cote du Palais, Quebec, QC, Canada G1R 2J6
    Eur Urol 47:695-702. 2005
    ..Evidence suggests that the insulin-like growth factor (IGF) family is important in prostate cancer. We evaluate the ability of IGF markers to predict biochemical recurrence-free survival (bRFS) following radical prostatectomy (RRP)...
  13. ncbi request reprint Insomnia in men treated with radical prostatectomy for prostate cancer
    Josee Savard
    Laval University Cancer Research Center and School of Psychology, Universite Laval, Quebec, Canada
    Psychooncology 14:147-56. 2005
    ....
  14. ncbi request reprint Tamoxifen as prophylaxis for prevention of gynaecomastia and breast pain associated with bicalutamide 150 mg monotherapy in patients with prostate cancer: a randomised, placebo-controlled, dose-response study
    Yves Fradet
    Centre de Recherche, Chuq Hotel Dieu de Quebec, Quebec, PQ, Canada
    Eur Urol 52:106-14. 2007
    ..To define the optimum tamoxifen dose for reducing bicalutamide (CASODEX) 150 mg monotherapy-induced breast events (ie, gynaecomastia or breast pain or both) without compromising disease control...
  15. ncbi request reprint PCA3 molecular urine assay for prostate cancer in men undergoing repeat biopsy
    Leonard S Marks
    Urological Sciences Research Foundation, Los Angeles, California 90232, USA
    Urology 69:532-5. 2007
    ..We evaluated the potential utility of the investigational prostate cancer gene 3 (PCA3) urine assay to predict the repeat biopsy outcome...
  16. pmc Rebuttal: Should Canadians be offered systematic prostate cancer screening? YES
    Yves Fradet
    Laval University in Quebec
    Can Fam Physician 53:1140-3. 2007
  17. doi request reprint PCA3: a molecular urine assay for predicting prostate biopsy outcome
    Ina L Deras
    Gen Probe, Inc, San Diego, California 92121, USA
    J Urol 179:1587-92. 2008
    ..We further characterized PCA3 performance in different groups of men and determined whether the PCA3 score could synergize with other clinical information to predict biopsy outcome...
  18. doi request reprint Membrane-type-1 matrix metalloproteinase, matrix metalloproteinase 2, and tissue inhibitor of matrix proteinase 2 in prostate cancer: identification of patients with poor prognosis by immunohistochemistry
    Dominique Trudel
    Department of Pathology, Centre Hospitalier Universitaire de Québec CHUQ and Université Laval, Quebec, Canada G1K 7P4
    Hum Pathol 39:731-9. 2008
    ..0001). This study suggests that MMP14 is involved mostly in Pca implantation and that MMP2 and TIMP2 expression by reactive stromal cells might be used as predictors of DFS in T3N0-2M0 Pca...
  19. ncbi request reprint uPM3, a new molecular urine test for the detection of prostate cancer
    Yves Fradet
    Universite Laval, Quebec, Quebec, Canada
    Urology 64:311-5; discussion 315-6. 2004
    ..To evaluate, in a multicenter study, the diagnostic performance of a new molecular test uPM3 for detecting prostate cancer cells in urine because of the need for better methods to identify patients at risk of prostate cancer...
  20. ncbi request reprint Neoadjuvant hormone therapy before salvage radiotherapy for an increasing post-radical prostatectomy serum prostate specific antigen level
    Rabi Tiguert
    Department of Urology, Centre Hospitalier Universitaire de Québec L Hôtel Dieu de Québec, Laval University Cancer Research Center, Canada
    J Urol 170:447-50. 2003
    ..We retrospectively evaluated the benefit of neoadjuvant androgen deprivation therapy administered before salvage external beam radiation treatment in patients with biochemical failure following retropubic radical prostatectomy (RRP)...
  21. ncbi request reprint Significance of MMP-2 expression in prostate cancer: an immunohistochemical study
    Dominique Trudel
    Departments of Pathology, Laval University, Centre Hospitalier Universitaire de Quebec, L Hôtel Dieu de Québec, Quebec, Canada
    Cancer Res 63:8511-5. 2003
    ..267; P = 0.0012). Increased MMP-2 expression by malignant prostatic epithelia is an independent predictor of decreased prostate cancer disease-free survival...
  22. ncbi request reprint Bicalutamide (Casodex) in the treatment of prostate cancer
    Yves Fradet
    Laval University, Cancer Research Center, CHUQ L Hôtel Dieu de Québec, 11 Cote du Palais, Quebec, QC G1R 2J6, Canada
    Expert Rev Anticancer Ther 4:37-48. 2004
    ..This paper reviews the evidence concerning the use of bicalutamide at all stages of the disease...
  23. ncbi request reprint Expression of p21 cell cycle protein is an independent predictor of response to salvage radiotherapy after radical prostatectomy
    Jerome Rigaud
    Laboratoire d Uro Oncologie Expérimentale, Centre de recherche en cancérologie de l Université Laval, CHUQ L Hôtel Dieu de Québec, Quebec, Canada
    Prostate 58:269-76. 2004
    ....
  24. ncbi request reprint [Salvage radical prostatectomy after radiotherapy failure in localized prostatic cancer]
    Jerome Rigaud
    Clinique Urologique, CHU de Nantes, France
    Prog Urol 12:1179-87. 2002
    ..The objective of this study was to evaluate salvage radical prostatectomy after failure of radiotherapy for localized prostate cancer...
  25. ncbi request reprint Identification of two genes differentially expressed upon different spatial configuration of the MGH-U3 human bladder cancer cells
    Serge Champetier
    Centre Hospitalier Universitaire de Quebec, Centre de recherche du Pavillon l Hôtel Dieu de Québec, 9 rue McMahon, Quebec City, Quebec, Canada G1R 2J6
    Urol Oncol 7:57-61. 2002
    ..The differential IGFBP-5 expression in this model system was also evidenced by Western analysis. The possible anti-proliferative role of IGFBP-5 in this model system is briefly discussed...
  26. ncbi request reprint Identification of PCA3 (DD3) in prostatic carcinoma by in situ hybridization
    Ion Popa
    Department of Pathology, L Hôtel Dieu de Québec, Centre Hospitalier Universitaire de Quebec, Laval University, QC, Canada
    Mod Pathol 20:1121-7. 2007
    ..Normal glands rarely express the marker, except those located in immediate proximity of neoplastic glands, suggesting the presence of precursor molecular changes...
  27. ncbi request reprint Controversies in the management of localized prostate cancer: consensus development by Canadian urologists
    Laurence H Klotz
    Sunnybrook and Women s College Health ciences Centre, Toronto, Ontario, Canada
    Can J Urol 9:30-5. 2002
    ..These summaries were collected and integrated into a set of questions. At the end of the congress, the attendees voted on the questions and controversies identified through the workshop process...
  28. doi request reprint Intravesical chemotherapy of high-grade bladder cancer with HTI-286, a synthetic analogue of the marine sponge product hemiasterlin
    Boris A Hadaschik
    The Prostate Centre at Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada
    Clin Cancer Res 14:1510-8. 2008
    ..In this study, we evaluate the inhibitory effects of HTI-286 on human bladder cancer growth, both in vitro and as an intravesical agent in an orthotopic murine model...
  29. ncbi request reprint Role of radical prostatectomy in high-risk prostate cancer
    Yves Fradet
    Department of Surgery, Universite Laval, Quebec, Canada
    Can J Urol 9:8-13. 2002
    ..However, urologists must be prepared for higher failure rates when performing this surgery in patients with high-risk disease compared to those with low-risk disease...
  30. doi request reprint The detection of genetic markers of bladder cancer in urine and serum
    Michele Lodde
    Department of Urology, Laval University, Hotel Dieu, Quebec, Canada
    Curr Opin Urol 18:499-503. 2008
    ..To review the most recent publications focusing on the use of genetic markers (DNA, RNA and nucleosides) in urine and serum and provide an opinion on their potential utility for screening, diagnosis and prognosis of urothelial carcinoma...
  31. ncbi request reprint A survey of urological manpower, technology, and resources in Canada
    Peter Pommerville
    Vancouver Island Health Authority, Victoria, British Columbia, Canada
    Can J Urol 11:2290-5. 2004
    ..Knowledge of the current status of manpower and resources is important in understanding the state of any medical specialty, and critical in planning for future recruitment, funding and infrastructure development...
  32. ncbi request reprint PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCG-induced granulomata: associations with localized stage progression
    Brant A Inman
    Department of Urology, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    Cancer 109:1499-505. 2007
    ..The role of PD-L1 was evaluated as a mechanism for local stage progression in urothelial carcinoma (UC) of the bladder...
  33. ncbi request reprint MAGE-A9 mRNA and protein expression in bladder cancer
    Valérie Picard
    Centre de recherche en cancérologie de l Université Laval, L Hôtel Dieu de Québec, Centre Hospitalier Universitaire de Quebec, 10 McMahon, Quebec City, Quebec, Canada
    Int J Cancer 120:2170-7. 2007
    ..These results show that MAGE-A9 is frequently expressed in superficial bladder cancer and could be a relevant target for immunotherapy or chemoimmunotherapy because its expression can be induced by chemotherapeutic drugs...
  34. ncbi request reprint Prostatic intraepithelial neoplasia in TURP specimens and subsequent prostate cancer
    Francois Meyer
    Laval University Cancer Research Center, Quebec City, Quebec, Canada
    Can J Urol 13:3255-60. 2006
    ....
  35. pmc Defining a 0.5-mb region of genomic gain on chromosome 6p22 in bladder cancer by quantitative-multiplex polymerase chain reaction
    Andrew J Evans
    Department of Pathology, University Health Network Princess Margaret Hospital, Toronto Ontario, Canada
    Am J Pathol 164:285-93. 2004
    ..This also represents the first study identifying DNA copy number increases for DEK in bladder cancer...
  36. ncbi request reprint Does prolonging the time to bladder cancer surgery affect long-term cancer control: a systematic review of the literature
    Yves Fradet
    Laval University, CHUQ Hôtel Dieu de Québec City, Quebec, Canada
    Can J Urol 13:37-47. 2006
    ..e., recurrence-free survival, overall survival)?..
  37. ncbi request reprint Cancer-testis antigen expression in bladder cancer
    Yves Fradet
    Laboratoire d Uro Oncologie Expérimentale, Centre de recherche en cancérologie de l Université Laval, CHUQ L Hôtel Dieu de Québec, Canada
    Prog Urol 15:1303-13. 2005
    ....
  38. ncbi request reprint ImmunoCyt/uCyt+ improves the sensitivity of urine cytology in patients followed for urothelial carcinoma
    Bernard Tetu
    Department of Pathology, Centre Hospitalier Universitaire de Quebec, L Hôtel Dieu de Québec, Laval University, Cote du Palais, Quebec, Canada
    Mod Pathol 18:83-9. 2005
    ..In conclusion, ImmunoCyt/uCyt may be used to postpone cystoscopies in patients followed for bladder cancer and may help to save cytologist and pathologist screening time...
  39. ncbi request reprint Safety and outcome of early catheter removal after radical retropubic prostatectomy
    Rabi Tiguert
    Department of Urology, Laval University Cancer Research Center, Centre Hospitalier Universitaire de Quebec, L Hôtel Dieu de Québec, Quebec, Canada
    Urology 63:513-7. 2004
    ..To assess the outcomes of patients who underwent radical retropubic prostatectomy (RRP) and had their indwelling urinary catheter removed on postoperative day 4 or later...
  40. ncbi request reprint Psychological functioning associated with prostate cancer: cross-sectional comparison of patients treated with radiotherapy, brachytherapy, or surgery
    Séverine Hervouet
    School of Psychology, Laval University, Canada
    J Pain Symptom Manage 30:474-84. 2005
    ..Although cross-sectional, these findings raise the possibility of a differential influence of treatments for prostate cancer on some aspects of psychological functioning...