Research Topics
| Catherine J FieldSummaryCountry: Canada Publications
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Publications
The immunological components of human milk and their effect on immune development in infantsCatherine J Field
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta T6G 2P5, Canada
J Nutr 135:1-4. 2005....
Feeding long-chain n-3 polyunsaturated fatty acids to obese leptin receptor-deficient JCR:LA- cp rats modifies immune function and lipid-raft fatty acid compositionMegan R Ruth
Nutrition and Metabolism Research Group, University of Alberta, Edmonton, AB T6G 2P5, Canada
Br J Nutr 101:1341-50. 2009..Feeding FO lowered the ex vivo inflammatory response, without altering IL-2 production from ConA-stimulated splenocytes which may occur independent of leptin signalling...
Trans-11 vaccenic acid reduces hepatic lipogenesis and chylomicron secretion in JCR:LA-cp ratsYe Wang
Alberta Institute for Human Nutrition, University of Alberta, Edmonton, AB, Canada
J Nutr 139:2049-54. 2009..The appreciable hypolipidemic benefits of VA may be attributed to a reduction in both intestinal CM and hepatic de novo lipogenesis pathways...
Chronic dietary n-3 PUFA intervention improves dyslipidaemia and subsequent cardiovascular complications in the JCR:LA- cp rat model of the metabolic syndromeJing Lu
Metabolic and Cardiovascular Diseases Laboratory, Alberta Institute for Human Nutrition, 4 10 Agriculture Forestry Centre, University of Alberta, Edmonton, AB, Canada T6G 2P5
Br J Nutr 105:1572-82. 2011..The chronic metabolic benefits of dietary n-3 PUFA may underlie the potential to reduce vascular complications during the MetS, including the observed reduction in the frequency (approximately 80 %) of late-stage 3 myocardial lesions...
Assessment of the mechanisms exerting glucose-lowering effects of dried peas in glucose-intolerant ratsKevin A Whitlock
Department of Physiology, University of Alberta, Edmonton, Alberta, Canada T6G 2R3
Br J Nutr 108:S91-102. 2012..NSC content appeared to have the most beneficial effects in improving glucose homeostasis but our ability to detect the effect of flavonoids may have been limited by their low concentration in the diet...
Irinotecan (CPT-11) chemotherapy alters intestinal microbiota in tumour bearing ratsXiaoxi B Lin
Department of Agriculture, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada
PLoS ONE 7:e39764. 2012..In conclusion, both colon cancer implantation and CPT-11-based chemotherapies disrupted the intestinal microbiota. Oral glutamine partially mitigated CPT-11 toxicity and induced temporary changes of the intestinal microbiota...
Effect of feeding a formula supplemented with long-chain polyunsaturated fatty acids for 14 weeks improves the ex vivo response to a mitogen and reduces the response to a soy protein in infants at low risk for allergyCatherine J Field
Department of Agricultural, Food, and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada
J Pediatr Gastroenterol Nutr 50:661-9. 2010..The aim of the study was to determine the effect of feeding LCP on immunity in healthy infants during the first 4 months of life...
Increased hypolipidemic benefits of cis-9, trans-11 conjugated linoleic acid in combination with trans-11 vaccenic acid in a rodent model of the metabolic syndrome, the JCR:LA-cp ratM Miriam Jacome-Sosa
Metabolic and Cardiovascular Diseases Laboratory, University of Alberta, Edmonton, AB, T6G 2P5, Canada
Nutr Metab (Lond) 7:60. 2010..The aim of this study was to evaluate potential additional hypolipidemic effects of purified forms of CLA and VA in an animal model of the metabolic syndrome (the JCR:LA-cp rat)...
Trans-11 vaccenic acid dietary supplementation induces hypolipidemic effects in JCR:LA-cp ratsYe Wang
Alberta Institute for Human Nutrition, University of Alberta, Edmonton, Canada
J Nutr 138:2117-22. 2008..In contrast, dietary VA had substantial hypo-triglyceridemic effects, suggesting a new bioactivity of this fatty acid that is typically found in ruminant-derived food products...
A randomized controlled crossover trial of the effect of ginseng consumption on the immune response to moderate exercise in healthy sedentary menPatricia D Biondo
Alberta Institute for Human Nutrition, Department of Agricultural, Food and Nutritional Science, University of Alberta, 4 126A HRIF East, Edmonton, AB T6G2P5, Canada
Appl Physiol Nutr Metab 33:966-75. 2008..The consumption of ginseng for 5 weeks had a limited effect on the immune response to an acute exercise protocol...
Dietary supplementation with vitamin E and C attenuates dexamethasone-induced glucose intolerance in ratsDeon B Williams
Department of Agriculture, Food and Nutritional Science, University of Alberta, Edmonton, Canada
Am J Physiol Regul Integr Comp Physiol 302:R49-58. 2012..There were no differences in mitochondrial enzymes in triceps muscles between groups. This study is the first to report that dietary Vit E/C supplementation can partially prevent DEX-induced glucose intolerance in rats...
The immunological components of human milkHeather J Hosea Blewett
Department of Agricultural, Food and Nutritional Sciences, Alberta Institute for Human Nutrition, University of Alberta, Edmonton, Alberta, T6G 2P5, Canada
Adv Food Nutr Res 54:45-80. 2008....
The potential for treatment with dietary long-chain polyunsaturated n-3 fatty acids during chemotherapyPatricia D Biondo
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada T6G 2P5
J Nutr Biochem 19:787-96. 2008....
The intestinal bioavailability of vaccenic acid and activation of peroxisome proliferator-activated receptor-α and -γ in a rodent model of dyslipidemia and the metabolic syndromeYe Wang
Metabolic and Cardiovascular Disease Laboratory, Molecular and Cell Biology of Lipids Group, Alberta Diabetes and Mazankowski Heart Institutes, University of Alberta, Edmonton, AB, Canada
Mol Nutr Food Res 56:1234-46. 2012....
Vaccenic acid favourably alters immune function in obese JCR:LA-cp ratsHeather J Blewett
Alberta Institute for Human Nutrition, Department of Agricultural, Food and Nutritional Sciences, University of Alberta, Edmonton, AB, T6G 2E1, Canada
Br J Nutr 102:526-36. 2009..These results indicate that dietary VA favourably alters the pro-inflammatory tendency of mesenteric lymphocytes from JCR:LA-cp rats...
Feeding a formula supplemented with long chain polyunsaturated fatty acids modifies the "ex vivo" cytokine responses to food proteins in infants at low risk for allergyCatherine J Field
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada
Pediatr Res 64:411-7. 2008..Feeding Formula+LCP for 4 wks maintained the higher TNF-alpha and IFN-gamma response to these food proteins...
Human health benefits of vaccenic acidCatherine J Field
Alberta Institute for Human Nutrition, Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, AB, Canada
Appl Physiol Nutr Metab 34:979-91. 2009..VA is the only known dietary precursor of c9,t11 conjugated linoleic acid (CLA), but recent data suggest that consumption of this trans fat may impart health benefits beyond those associated with CLA...
Glutamine supplementation improves intestinal barrier function in a weaned piglet model of Escherichia coli infectionJulia B Ewaschuk
Department of Agricultural, Food and Nutritional Science, University of Alberta, 4 126A HRIF East, Edmonton, AB, Canada T6G 2P5
Br J Nutr 106:870-7. 2011..Gln supplementation may be useful in reducing the severity of weaning-related gastrointestinal infections, by reducing the mucosal cytokine response and altering intestinal barrier function...
In vitro intestinal glucose uptake is inhibited by galactomannan from Canadian fenugreek seed (Trigonella foenum graecum L) in genetically lean and obese ratsAnchalee Srichamroen
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada T6G 2P5
Nutr Res 29:49-54. 2009..These results suggest that the galactomannan, because of its viscous property, has the potential to reduce intestinal absorption of low or high concentrations of glucose and hence for the benefit of blood glucose management...
The Modifying Effects of Galactomannan from Canadian-Grown Fenugreek (Trigonella foenum-graecum L.) on the Glycemic and Lipidemic Status in RatsAnchalee Srichamroen
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta T6G 2P5, Canada
J Clin Biochem Nutr 43:167-74. 2008..Overall, this study demonstrated that feeding GAL from Canadian-grown fenugreek seeds has the potential to alter glycemic and lipidemic status and reduce abdominal fat in normal rats...
Early risk determinants and later health outcomes: implications for research prioritization and the food supply. Summary of the workshopCatherine J Field
Alberta Institute for Human Nutrition, the Department of Agricultural, Food and Nutritional Science, The University of Alberta, Edmonton, Canada
Am J Clin Nutr 89:1533S-1539S. 2009..This was followed by a discussion of how the food industry might assist in the acquisition and translation of the knowledge of the determinants of disease to improve human health...
Conjugated linoleic acid decreases mcf-7 human breast cancer cell growth and insulin-like growth factor-1 receptor levelsDanielle L Amarù
Alberta Institute for Human Nutrition, Department of Agricultural, Food and Nutritional Science, University of Alberta, 4 126A HRIF East, Edmonton, AB T6G2P5, Canada
Lipids 44:449-58. 2009....
Single and combined supplementation of glutamine and n-3 polyunsaturated fatty acids on host tolerance and tumour response to 7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxy-camptothecin (CPT-11)/5-fluorouracil chemotherapy in rats bearing Ward coloHongyu Xue
Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta, Canada
Br J Nutr 102:434-42. 2009....
Docosahexanoic Acid Improves Chemotherapy Efficacy by Inducing CD95 Translocation to Lipid Rafts in ER(-) Breast Cancer CellsJulia B Ewaschuk
Department of Agricultural, Food and Nutritional Sciences, 4 126A Li Ka Shing Health Research Innovation Centre, University of Alberta, Edmonton, AB, T6G 2E1, Canada
Lipids 47:1019-30. 2012..05). This study demonstrated that pre-treatment of estrogen receptor negative MDA-MB-231 cells with DHA increased the anti-cancer effects of dox and presents evidence to suggest that this may be mediated in part by CD95-induced apoptosis...
Effect of hydration status on high-intensity rowing performance and immune functionMichael A Penkman
Faculty of Physical Education and Recreation, Department of Agricultural, Food, and Nutritional Science, University of Alberta, Edmonton, AB, Canada
Int J Sports Physiol Perform 3:531-46. 2008..This study determined the effect of dehydration and rehydration (DR) on performance, immune cell response, and tympanic temperature after high-intensity rowing exercise...
Abnormal immune responses in fa/fa Zucker rats and effects of feeding conjugated linoleic acidMegan R Ruth
Department of Agricultural Food and Nutritional Science, University of Alberta, Edmonton, Alberta, Canada
Obesity (Silver Spring) 16:1770-9. 2008..The objective of this study was to characterize immune function in the fa/fa Zucker rat, and to determine the effects of feeding conjugated linoleic acid (CLA) isomers on immune function...
Effect of providing a formula supplemented with long-chain polyunsaturated fatty acids on immunity in full-term neonatesCatherine J Field
Nutrition and Metabolism Research Group, University of Alberta, Edmonton, Alberta T6G 2P5, Canada
Br J Nutr 99:91-9. 2008..Since many diseases have a strong immunological component, these immune changes may be of physiological importance to the developing infant...
The role of dietary long-chain n-3 fatty acids in anti-cancer immune defense and R3230AC mammary tumor growth in rats: influence of diet fat compositionLindsay E Robinson
Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Canada
Breast Cancer Res Treat 73:145-60. 2002..These findings warrant further consideration when designing dietary recommendations...
