Li Fan

Summary

Country: Canada

Publications

  1. ncbi Molecular cloning and characterization of hNP22: a gene up-regulated in human alcoholic brain
    L Fan
    Department of Biochemistry, The University of Queensland, Brisbane, Australia
    J Neurochem 76:1275-81. 2001
  2. ncbi Genetic study of alcoholism and novel gene expression in the alcoholic brain
    Li Fan
    Department of Biochemistry and Molecular Biology, The University of Queensland, Brisbane, Australia
    Addict Biol 9:11-8. 2004
  3. doi Cortactin activation by FVIIa/tissue factor and PAR2 promotes endothelial cell migration
    Tang Zhu
    Department of Pediatrics, Maisonneuve Rosemont Hospital Research Centre, University of Montreal, Quebec, Canada
    Am J Physiol Regul Integr Comp Physiol 300:R577-85. 2011
  4. doi MALAT-1, a non protein-coding RNA is upregulated in the cerebellum, hippocampus and brain stem of human alcoholics
    Rosemarie Kryger
    Department of Biochemistry, School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, Australia
    Alcohol 46:629-34. 2012
  5. ncbi Proinflammatory gene induction by platelet-activating factor mediated via its cognate nuclear receptor
    A Marilise Marrache
    Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada
    J Immunol 169:6474-81. 2002
  6. ncbi Intracellular-specific colocalization of prostaglandin E2 synthases and cyclooxygenases in the brain
    Alejandro Vazquez-Tello
    Deptartment of Pediatrics, Research Center of Hôpital Sainte Justine, 3175, Cote Sainte Catherine, Montreal, Quebec, Canada H3T 1C5
    Am J Physiol Regul Integr Comp Physiol 287:R1155-63. 2004
  7. ncbi Smooth muscle-specific expression of SV40 large TAg induces SMC proliferation causing adaptive arterial remodeling
    Jurgen R Sindermann
    Krannert Institute of Cardiology and Indiana Center for Vascular Biology and Medicine, Indiana University Medical Center, Indianapolis 46202, USA
    Am J Physiol Heart Circ Physiol 283:H2714-24. 2002
  8. ncbi Identification of a novel gentisate 1,2-dioxygenase from Silicibacter pomeroyi
    Dongqi Liu
    College of Environmental Sciences, Peking University, Beijing, 100871, P R China
    Biotechnol Lett 29:1529-35. 2007
  9. doi Sarcoplasmic reticulum Ca2+ release channel ryanodine receptor (RyR2) plays a crucial role in aconitine-induced arrhythmias
    Min Fu
    School of Medicine and Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, People s Republic of China
    Biochem Pharmacol 75:2147-56. 2008
  10. pmc XPD helicase structures and activities: insights into the cancer and aging phenotypes from XPD mutations
    Li Fan
    Department of Molecular Biology, Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Cell 133:789-800. 2008

Collaborators

  • P A Wilce
  • W Chen
  • Fernand Gobeil
  • Jurgen R Sindermann
  • Fumio Hanaoka
  • Jean Sebastien Joyal
  • Sylvain Chemtob
  • Rosemarie Kryger
  • Tang Zhu
  • Alejandro Vazquez-Tello
  • Yuichi Matsushima
  • Min Fu
  • Xin Hou
  • Joseph A Mancini
  • Dongqi Liu
  • Daya R Varma
  • A Marilise Marrache
  • Vincent Jaquet
  • Georges Etienne Rivard
  • Zhuo Shao
  • Martin Leduc
  • Karine Zaniolo
  • Chun Yang
  • Pierre Hardy
  • Jean Claude Honoré
  • Przemyslaw Sapieha
  • Kent L Thornburg
  • Zhao Wang
  • Ru Xin Li
  • Laurie S Kaguni
  • Carol L Farr
  • Guo Wei He
  • Junming Quan
  • Jinren Ni
  • Tingting Zhu
  • Hongchun Guo
  • Ronald I Clyman
  • Christiane Quiniou
  • Marek Rola-Pleszczynski
  • Alfredo Ribeiro-Da-Silva
  • Ghassan Bkaily
  • Janos G Filep
  • Sylvie G Bernier
  • Jana Stankova
  • Annie Bourdeau
  • Sanaa Choufani
  • Martin G Sirois

Detail Information

Publications13

  1. ncbi Molecular cloning and characterization of hNP22: a gene up-regulated in human alcoholic brain
    L Fan
    Department of Biochemistry, The University of Queensland, Brisbane, Australia
    J Neurochem 76:1275-81. 2001
    ..The results suggest that hNP22 may have a role in alcohol-related adaptations and may mediate regulatory signal transduction pathways in neurones...
  2. ncbi Genetic study of alcoholism and novel gene expression in the alcoholic brain
    Li Fan
    Department of Biochemistry and Molecular Biology, The University of Queensland, Brisbane, Australia
    Addict Biol 9:11-8. 2004
    ..This review discusses the current information on the genetic basis of alcoholism and the induction and characterization of these alcohol-responsive genes...
  3. doi Cortactin activation by FVIIa/tissue factor and PAR2 promotes endothelial cell migration
    Tang Zhu
    Department of Pediatrics, Maisonneuve Rosemont Hospital Research Centre, University of Montreal, Quebec, Canada
    Am J Physiol Regul Integr Comp Physiol 300:R577-85. 2011
    ..Overall, we demonstrate a novel regulation and role for cortactin in FVIIa/TF-mediated endothelial cell migration that occurs through a PAR2 and RhoA dependent mechanism...
  4. doi MALAT-1, a non protein-coding RNA is upregulated in the cerebellum, hippocampus and brain stem of human alcoholics
    Rosemarie Kryger
    Department of Biochemistry, School of Chemistry and Molecular Biosciences, The University of Queensland, St Lucia, Australia
    Alcohol 46:629-34. 2012
    ..As MALAT-1 regulates RNA processing, this suggests that alcohol-induced upregulation of MALAT-1 represents an important novel mechanism for alcohol actions in the CNS...
  5. ncbi Proinflammatory gene induction by platelet-activating factor mediated via its cognate nuclear receptor
    A Marilise Marrache
    Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada
    J Immunol 169:6474-81. 2002
    ..This study describes for the first time the nucleus as a putative organelle capable of generating PAF and expresses its receptor, which upon stimulation induces the expression of the proinflammatory gene COX-2...
  6. ncbi Intracellular-specific colocalization of prostaglandin E2 synthases and cyclooxygenases in the brain
    Alejandro Vazquez-Tello
    Deptartment of Pediatrics, Research Center of Hôpital Sainte Justine, 3175, Cote Sainte Catherine, Montreal, Quebec, Canada H3T 1C5
    Am J Physiol Regul Integr Comp Physiol 287:R1155-63. 2004
    ..Hence, contrary to a previously proposed model of exclusive COX-2/mPGES-1 coordination, COX-2 can coordinate with mPGES-1 and/or cPGES in the brain, depending on the cell compartment and the age group...
  7. ncbi Smooth muscle-specific expression of SV40 large TAg induces SMC proliferation causing adaptive arterial remodeling
    Jurgen R Sindermann
    Krannert Institute of Cardiology and Indiana Center for Vascular Biology and Medicine, Indiana University Medical Center, Indianapolis 46202, USA
    Am J Physiol Heart Circ Physiol 283:H2714-24. 2002
    ..This establishes a new model of adaptive vessel remodeling occurring in response to a proliferative input in the absence of mechanical injury or primary flow perturbation...
  8. ncbi Identification of a novel gentisate 1,2-dioxygenase from Silicibacter pomeroyi
    Dongqi Liu
    College of Environmental Sciences, Peking University, Beijing, 100871, P R China
    Biotechnol Lett 29:1529-35. 2007
    ..The K (m) and K (cat)/K (m) for gentisate were 12 muM and 653 x 10(4) M(-1 )s(-1); the pI was 4.6-4.8. It was optimally active at 40 degrees C and pH 8.0...
  9. doi Sarcoplasmic reticulum Ca2+ release channel ryanodine receptor (RyR2) plays a crucial role in aconitine-induced arrhythmias
    Min Fu
    School of Medicine and Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing 100084, People s Republic of China
    Biochem Pharmacol 75:2147-56. 2008
    ..The present study demonstrates a potential method for preventing aconitine-induced arrhythmias by inhibiting Ca(2+) leakage through the sarcoplasmic reticulum RyR(2) channel...
  10. pmc XPD helicase structures and activities: insights into the cancer and aging phenotypes from XPD mutations
    Li Fan
    Department of Molecular Biology, Skaggs Institute of Chemical Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
    Cell 133:789-800. 2008
    ..These results provide a foundation for understanding disease consequences of mutations in XPD and related 4Fe-4S helicases including FancJ...
  11. pmc Physiological and biochemical defects in carboxyl-terminal mutants of mitochondrial DNA helicase
    Yuichi Matsushima
    Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824 1319, USA
    J Biol Chem 283:23964-71. 2008
    ..Our findings may be applicable to understand the role of the carboxyl-terminal region in superfamily 4 DNA helicases in general...
  12. ncbi Survival motor neuron (SMN) protein: role in neurite outgrowth and neuromuscular maturation during neuronal differentiation and development
    Li Fan
    Centre de Recherche, Hopital Sainte Justine, Montreal, Quebec, Canada H3T 1C5
    Hum Mol Genet 11:1605-14. 2002
    ..The primary SMA pathology most likely initiates in the peripheral axon--the result of deficient neurite outgrowth and/or neuromuscular maturation...
  13. ncbi Conserved XPB core structure and motifs for DNA unwinding: implications for pathway selection of transcription or excision repair
    Li Fan
    Life Sciences Division, Department of Molecular Biology, Lawrence Berkeley National Laboratory, Berkeley, California 94720, USA
    Mol Cell 22:27-37. 2006
    ..Together, these results provide an unexpected mechanism of DNA unwinding with implications for XPB damage verification in nucleotide excision repair...