Mahyar Etminan

..It is a spironolactone-derivative, and its antimineralocorticoid effects could irritate the gastrointestinal tract leading to symptoms of irritable bowel syndrome (IBS)...

..It is conjectured that drospirenone, taken alone or concomitantly with spironolactone, may be associated with an increased risk of hyperkalemia...

..We conclude that dietary vitamin E may have a neuroprotective effect attenuating the risk of PD. These results require confirmation in randomised controlled trials...

..In addition, the putative protection against pneumonia may instead be related to general inhibition of the renin-angiotensin system...

..We also discuss the potential problem of discordant results and urge pharmacoepidemiologists to develop good practice guidelines for the conduct of pharmacoepidemiologic studies...

..Because of these discrepant results we sought to explore the association between selenium intake and prostate cancer by conducting a systematic review and meta-analysis of the literature...

..01]). This effect was not seen with past users (RR=1.18 [95% CI, 0.89-1.59]). Based on the results of our study current users of NSAIDs may be at a slightly higher risk of developing PD. More studies are needed to confirm this finding...

..We sought to further explore this association and also explore the role of angiotensin-converting enzyme inhibitors (ACE-Is) with respect to the development of AMD...

..To determine whether use of oral bisphosphonates is associated with an increased risk of aseptic osteonecrosis (AON) among a cohort of elderly cardiovascular patients...

..More rigourous standards of reporting ADEs in randomised trials, as well as better indexing of ADE terminology in medical databases, could one day make systematic reviews of ADEs a powerful tool for practising clinicians...

..A time-dependent Cox model was used to estimate adjusted rate ratios for users and non-users of NSAIDs. The results of our study did not show a protective effect of NSAIDs for PD (rate ratio 0.84, 95% CI 0.81-1.09)...

..To examine the potential efficacy of hydroxymethyl-glutaryl-coenzyme A reductase inhibitors (statins) in the prevention of epilepsy...

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..To quantify the risk of Alzheimer's disease in users of all non-steroidal anti-inflammatory drugs (NSAIDs) and users of aspirin and to determine any influence of duration of use...

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..To determine whether intake of tomato products reduces the risk of prostate cancer using a meta-analysis...

..To test this hypothesis, we examined the British Columbia Population DataBase to determine the frequency of prescription of combination eye drops as initial therapy in glaucoma patients or glaucoma suspects...

..We conducted a study to determine the magnitude of this risk compared with other formulations of oral contraceptives...

..There have been several published reports of inflammatory ocular adverse events, mainly uveitis and scleritis, among patients taking oral bisphosphonates. We examined the risk of these adverse events in a pharmacoepidemiologic cohort study...

..Fluoroquinolones are commonly prescribed classes of antibiotics. Despite numerous case reports of ocular toxicity, a pharmacoepidemiological study of their ocular safety, particularly retinal detachment, has not been performed...

..To examine the possible link of acute-onset glaucoma with topiramate...

..Epidemiologic studies have identified an increased risk of asthma with acetaminophen use, but the results have been conflicting. We sought to quantify the association between acetaminophen use and the risk of asthma in children and adults...

..This study sought to quantify the risk of cataracts with SSRIs by conducting a pharmacoepidemiologic study using the linked administrative databases in the province of Quebec, Canada...

..The objective of this study was to perform a systematic review of the literature evaluating the effect of statin therapy on outcomes in patients with COPD...

..To determine the magnitude of risk of cardiovascular mortality in patients with rheumatoid arthritis (RA) compared with the general population through a meta-analysis of observational studies...

..Recent studies that have attempted to explore this risk have had conflicting results. We sought to explore the risk of ICS and fractures among older adults by conducting a systematic review and meta-analysis of the literature...

..08), myocardial infarction or angina (RR 0.89, 95% CI 0.68-1.16), or overall mortality (RR 0.95, 95% CI 0.81-1.12). CONCLUSION: Our results do not support routine use of antichlamydial therapy for secondary prevention of coronary events...

..The aim of this study was to systematically review the literature on the effect of statins on mortality in patients with infection and/or sepsis...

..By using the principles of epidemiology, the nested case-control study allows for the control of confounding variables, as well as better quantification of time-dependent exposures...

..abstract:..

..Randomized, controlled trials are needed to address the efficacy of these agents specifically in different types of dementia...

..To explore the suggested association between atypical neuroleptic use and the development of diabetes mellitus, with a focus on older adults...

..In this systematic literature review we sought to determine whether tattooing is a risk factor for the transmission of hepatitis C...

..To examine the effect of lipid-lowering agents in the development of age-related macular degeneration (AMD) through the techniques of meta-analysis...

..To explore and quantify the association between amalgam restorations and MS we have conducted a systematic review and meta-analysis of the literature...

..Use of pramipexole seems to be associated with a higher risk of hallucinations than use of ropinirole when compared with placebo...

..The use of nonsteroidal anti-inflammatory drugs (NSAIDs) may be associated with reduced risk for breast cancer, but results from these studies of the association have been inconsistent...

..Results have been conflicting due, in part, to sub-optimal methods used to explore this interaction...

..Many studies have examined the relationship between the use of psychotropic medications and the risk of fractures, but these studies have reported conflicting results...

..68 to 0.93). CONCLUSION: Angiotensin II receptor antagonists appear to be effective in preventing headaches, but the mechanism of this benefit and the types of headaches that are prevented are not known. Randomized trials are warranted...

..To explore the association between migraine and risk of ischaemic stroke...