F Gagne

Summary

Affiliation: Environment Canada
Country: Canada

Publications

  1. ncbi request reprint Implication of site quality on mitochondrial electron transport activity and its interaction with temperature in feral Mya arenaria clams from the Saguenay Fjord
    F Gagne
    River Ecosystems Research, Aquatic Ecosystem Protection Division, Environment Canada, 105 McGill Street, Montreal, Quebec, Canada H2Y 2E7
    Environ Res 103:238-46. 2007
  2. doi request reprint Screening test of silver nanoparticles in biological samples by graphite furnace-atomic absorption spectrometry
    F Gagne
    Emerging Methods Section, Aquatic Contaminants Research Division, Water Science and Technology Directorate, Environment Canada, Montreal, QC, Canada
    Anal Bioanal Chem 404:2067-72. 2012
  3. ncbi request reprint In vitro immunotoxicity of untreated and treated urban wastewaters using various treatment processes to rainbow trout leucocytes
    François Gagné
    Emerging Methods, Aquatic Contaminants Research Division, Water Science and Technology, Environment Canada, 105 McGill Street, Montreal, Quebec, Canada
    J Environ Sci (China) 25:1400-7. 2013
  4. doi request reprint Sublethal effects of silver nanoparticles and dissolved silver in freshwater mussels
    F Gagne
    Emerging Methods Section, Aquatic Contaminants Research Division, Water Science and Technology Directorate, Environment Canada, Montreal, Quebec, Canada
    J Toxicol Environ Health A 76:479-90. 2013
  5. doi request reprint A comparative toxicogenomic investigation of oil sand water and processed water in rainbow trout hepatocytes
    F Gagne
    Emerging Methods, Aquatic Contaminants Research Division, Water Science and Technology, Environment Canada, 105 Mc Gill Street, Montreal, QC, H2Y 2E7, Canada
    Arch Environ Contam Toxicol 65:309-23. 2013
  6. doi request reprint The effects of zinc oxide nanoparticles on the metallome in freshwater mussels
    F Gagne
    Emerging Methods Section, Aquatic Contaminants Research Division, Water Science and Technology Directorate, Environment Canada, 105 McGill, Montreal, QC, Canada H2Y 2E7
    Comp Biochem Physiol C Toxicol Pharmacol 158:22-8. 2013
  7. ncbi request reprint Stress-related gene expression changes in rainbow trout hepatocytes exposed to various municipal wastewater treatment influents and effluents
    F Gagne
    Emerging Methods, Aquatic Contaminants Research Division, Water Science and Technology, Environment Canada, 105 McGill Street, Montreal, QC, Canada
    Environ Sci Pollut Res Int 20:1706-18. 2013
  8. doi request reprint Toxicity of silver nanoparticles to rainbow trout: a toxicogenomic approach
    F Gagne
    Fluvial Ecosystem Research, Water Science and Technology, Environment Canada, Montreal, Que, Canada H2Y 2E7
    Chemosphere 89:615-22. 2012
  9. ncbi request reprint Immunotoxic potential of aeration lagoon effluents for the treatment of domestic and hospital wastewaters in the freshwater mussel Elliptio complanata
    François Gagné
    Fluvial Ecosystem Research, Environment Canada, Montreal, Quebec H2Y 2E7, Canada
    J Environ Sci (China) 24:781-9. 2012
  10. doi request reprint Differential changes in gene expression in rainbow trout hepatocytes exposed to extracts of oil sands process-affected water and the Athabasca River
    F Gagne
    Fluvial Ecosystem Research, Aquatic Ecosystem Protection Division, Water Science and Technology, Environment Canada, 105 McGill Street, Montreal, Quebec, Canada H2Y 2E7
    Comp Biochem Physiol C Toxicol Pharmacol 155:551-9. 2012

Collaborators

Detail Information

Publications62

  1. ncbi request reprint Implication of site quality on mitochondrial electron transport activity and its interaction with temperature in feral Mya arenaria clams from the Saguenay Fjord
    F Gagne
    River Ecosystems Research, Aquatic Ecosystem Protection Division, Environment Canada, 105 McGill Street, Montreal, Quebec, Canada H2Y 2E7
    Environ Res 103:238-46. 2007
    ..The gradual warming of clam habitats would likely worsen the impacts of pollution in feral clam populations...
  2. doi request reprint Screening test of silver nanoparticles in biological samples by graphite furnace-atomic absorption spectrometry
    F Gagne
    Emerging Methods Section, Aquatic Contaminants Research Division, Water Science and Technology Directorate, Environment Canada, Montreal, QC, Canada
    Anal Bioanal Chem 404:2067-72. 2012
    ..The proposed methodology was capable of determining the presence of dissolved Ag(+) from 20 nm in prepared mixtures, and in the liver of rainbow trout exposed to either dissolved or 20-nm nano-Ag...
  3. ncbi request reprint In vitro immunotoxicity of untreated and treated urban wastewaters using various treatment processes to rainbow trout leucocytes
    François Gagné
    Emerging Methods, Aquatic Contaminants Research Division, Water Science and Technology, Environment Canada, 105 McGill Street, Montreal, Quebec, Canada
    J Environ Sci (China) 25:1400-7. 2013
    ..In conclusion, municipal effluents have the potential to alter the immune system in fish and more research will be needed to improve the treatments of wastewaters to better protect the quality of the aquatic environment...
  4. doi request reprint Sublethal effects of silver nanoparticles and dissolved silver in freshwater mussels
    F Gagne
    Emerging Methods Section, Aquatic Contaminants Research Division, Water Science and Technology Directorate, Environment Canada, Montreal, Quebec, Canada
    J Toxicol Environ Health A 76:479-90. 2013
    ..It was concluded that the presence of nAg not only increases the toxic loadings of released Ag ions but also generates other and perhaps cumulative effects of nanoparticle-induced toxicity related to size and surface properties...
  5. doi request reprint A comparative toxicogenomic investigation of oil sand water and processed water in rainbow trout hepatocytes
    F Gagne
    Emerging Methods, Aquatic Contaminants Research Division, Water Science and Technology, Environment Canada, 105 Mc Gill Street, Montreal, QC, H2Y 2E7, Canada
    Arch Environ Contam Toxicol 65:309-23. 2013
    ..The observed changes in cell toxicity and gene expression therefore support the hypothesis that OSPW has a distinct toxic fingerprint from OSLW and OSW...
  6. doi request reprint The effects of zinc oxide nanoparticles on the metallome in freshwater mussels
    F Gagne
    Emerging Methods Section, Aquatic Contaminants Research Division, Water Science and Technology Directorate, Environment Canada, 105 McGill, Montreal, QC, Canada H2Y 2E7
    Comp Biochem Physiol C Toxicol Pharmacol 158:22-8. 2013
    ..In conclusion, the use of a "metallomic" approach was used to discriminate changes following exposure to nanoZnO and dissolved Zn in freshwater mussels and provided insights into the interaction of forms of Zn in ME towards mussels...
  7. ncbi request reprint Stress-related gene expression changes in rainbow trout hepatocytes exposed to various municipal wastewater treatment influents and effluents
    F Gagne
    Emerging Methods, Aquatic Contaminants Research Division, Water Science and Technology, Environment Canada, 105 McGill Street, Montreal, QC, Canada
    Environ Sci Pollut Res Int 20:1706-18. 2013
    ....
  8. doi request reprint Toxicity of silver nanoparticles to rainbow trout: a toxicogenomic approach
    F Gagne
    Fluvial Ecosystem Research, Water Science and Technology, Environment Canada, Montreal, Que, Canada H2Y 2E7
    Chemosphere 89:615-22. 2012
    ..Exposure to nano-Ag involved genes in inflammation and dissolved Ag involved oxidative stress and protein stability. Hence, the toxicity of Ag will differ depending on the presence of Ag nanoparticles and aggregates...
  9. ncbi request reprint Immunotoxic potential of aeration lagoon effluents for the treatment of domestic and hospital wastewaters in the freshwater mussel Elliptio complanata
    François Gagné
    Fluvial Ecosystem Research, Environment Canada, Montreal, Quebec H2Y 2E7, Canada
    J Environ Sci (China) 24:781-9. 2012
    ..In conclusion, exposure of mussels to treated aerated lagoon wastewater is deleterious to freshwater mussels where the immune system is compromised...
  10. doi request reprint Differential changes in gene expression in rainbow trout hepatocytes exposed to extracts of oil sands process-affected water and the Athabasca River
    F Gagne
    Fluvial Ecosystem Research, Aquatic Ecosystem Protection Division, Water Science and Technology, Environment Canada, 105 McGill Street, Montreal, Quebec, Canada H2Y 2E7
    Comp Biochem Physiol C Toxicol Pharmacol 155:551-9. 2012
    ..This study identified a suite of gene targets that responded specifically to OSPW extracts, which could serve as toxicogenomic fingerprints of OSPW contamination...
  11. ncbi request reprint Ecotoxicity of CdTe quantum dots to freshwater mussels: impacts on immune system, oxidative stress and genotoxicity
    F Gagne
    Fluvial Ecosystem Research, Environment Canada, 105 McGill Street, Montreal, Quebec, Canada H2Y 2E7
    Aquat Toxicol 86:333-40. 2008
    ..A multivariate analysis revealed that the various response patterns differed based on the concentration of CdTe, thus permitting the identification of biomarkers associated with the form (colloidal vs. molecular) of cadmium...
  12. ncbi request reprint Immunotoxic effects on freshwater mussels of a primary-treated wastewater before and after ozonation: a pilot plant study
    F Gagne
    Fluvial Ecosystem Research, Environment Canada, Montreal, Quebec, Canada
    Ecotoxicol Environ Saf 69:366-73. 2008
    ..Investigations aimed at examining the impacts of sustained inflammation on the host's capacity to remove potentially pathogenic bacteria are recommended...
  13. ncbi request reprint Neurotoxicological effects of a primary and ozonated treated wastewater on freshwater mussels exposed to an experimental flow-through system
    F Gagne
    St Lawrence Centre, Environment Canada, Montreal, QC, Canada
    Comp Biochem Physiol C Toxicol Pharmacol 146:460-70. 2007
    ..e. morphine) in the effluent. In general, ozonation reduced the severity of the responses, indicating that this disinfection strategy does not increase neurotoxicity to mussels...
  14. ncbi request reprint Relationships between intertidal clam population and health status of the soft-shell clam Mya arenaria in the St. Lawrence Estuary and Saguenay Fjord (Québec, Canada)
    F Gagne
    Fluvial Ecosystems Research, Aquatic Ecosystems Research Protection Branch, Environment Canada, 105 McGill Street, Montreal, Quebec, Canada H2Y 2E7
    Environ Int 34:30-43. 2008
    ..Intertidal clam populations were influenced by a distance gradient effect (salinity), where immunocompetence, in addition to energy status, was the strongest physiological parameter related to clam population metrics...
  15. ncbi request reprint Spatial variations in biomarkers of Mytilus edulis mussels at four polluted regions spanning the Northern Hemisphere
    F Gagne
    Fluvial Ecosystem Research, Environment Canada, 105 McGill Street, Montreal, Que, Canada
    Environ Res 107:201-17. 2008
    ..Regional observations of biomarkers of energy status, gametogenesis and pollutant-related effects were influenced by nutrition, oxygen availability (eutrophication), and thermal history...
  16. ncbi request reprint Effects of pharmaceutical products and municipal wastewaters on temperature-dependent mitochondrial electron transport activity in Elliptio complanata mussels
    F Gagne
    St Lawrence Centre, Environment Canada, 105 McGill St, Montreal, QC, Canada H2Y 2E7
    Comp Biochem Physiol C Toxicol Pharmacol 143:388-93. 2006
    ....
  17. doi request reprint Impacts of pollution in feral Mya arenaria populations: the effects of clam bed distance from the shore
    F Gagne
    Fluvial Ecosystem Research Section, Environment Canada, 105 McGill Street, Montreal, Quebec, Canada
    Sci Total Environ 407:5844-54. 2009
    ..These biomarkers were affected by the distance of the clam beds from the shore, site quality (pollution) and reproduction activity...
  18. ncbi request reprint Neurochemical effects of benzodiazepine and morphine on freshwater mussels
    F Gagne
    Fluvial Ecosystem Research Section, Environment Canada, 105 McGill Street, Montreal, Quebec, Canada H2Y 2E7
    Comp Biochem Physiol C Toxicol Pharmacol 152:207-14. 2010
    ..In conclusion, the data warrant more studies on the analysis of opiates and benzodiazepines in municipal effluents to better address the potential environmental hazard of these neuroactive drug classes to aquatic organisms...
  19. doi request reprint Monitoring of a flame retardant (tetrabromobisphenol A) toxicity on different microalgae assessed by flow cytometry
    Timothée Debenest
    François GAGNE, Environment Canada, Fluvial Ecosystem Research, Montreal, Quebec, Canada
    J Environ Monit 12:1918-23. 2010
    ..Abundance increase of these cells was higher in N. palea than in P. subcapitata. No similar trends were observed in C. reinhardtii populations due to the very high mortality of this microalgal species exposed to TBBPA...
  20. doi request reprint Evidence of feminization in wild Elliptio complanata mussels in the receiving waters downstream of a municipal effluent outfall
    F Gagne
    Environment Canada, Fluvial Ecosystem Research, 105 McGill, 7th Floor, Montreal, Quebec, Canada H2Y 2E7
    Comp Biochem Physiol C Toxicol Pharmacol 153:99-106. 2011
    ..This study provides the first evidence of feminization in wild mussel populations and the disruption in gonad physiology by exposure to municipal effluents...
  21. doi request reprint Alterations in DNA metabolism in Elliptio complanata mussels after exposure to municipal effluents
    F Gagne
    Environment Canada, Fluvial Ecosystem Research, Montreal, Que, Canada
    Comp Biochem Physiol C Toxicol Pharmacol 154:100-7. 2011
    ..We conclude that municipal effluents contain a complex mixture of pollutants that could modulate DNA synthesis and repair mechanisms in mussels...
  22. ncbi request reprint Evaluation of estrogenic effects of municipal effluents to the freshwater mussel Elliptio complanata
    F Gagne
    St Lawrence Centre, 105 McGill Street, 7th Floor, Montreal, Quebec H2Y 2E7, Canada
    Comp Biochem Physiol C Toxicol Pharmacol 128:213-25. 2001
    ..We conclude that municipal effluents contain bio-available xenoestrogens at levels sufficient to elicit effects in freshwater mussels...
  23. doi request reprint An examination of the toxic properties of water extracts in the vicinity of an oil sand extraction site
    F Gagne
    Fluvial Ecosystem Research, Aquatic Ecosystem Protection Division, Water Science and Technology, Environment Canada, 105 McGill Street, Montreal, Quebec, Canada H2Y 2E7
    J Environ Monit 13:3075-86. 2011
    ..There is a need for more research into specific biomarkers of toxicity from OS tailings compounds such as naphthenic acids, light PAHs among others, which are a characteristic fingerprint of OS extraction activities...
  24. ncbi request reprint Toxicological effects of primary-treated urban wastewaters, before and after ozone treatment, on freshwater mussels (Elliptio complanata)
    F Gagne
    St Lawrence Centre, Environment Canada, 105 Mc Gill, Montreal, Quebec, Canada
    Comp Biochem Physiol C Toxicol Pharmacol 145:542-52. 2007
    ..Ozone treatment could significantly decrease either the toxic potency or intensity of urban pollutants at the expense of increased oxidative stress in gills of freshwater mussels...
  25. ncbi request reprint Altered exoskeleton composition and vitellogenesis in the crustacean Gammarus sp. collected at polluted sites in the Saguenay Fjord, Quebec, Canada
    F Gagne
    St Lawrence Centre, Environment Canada, Research on Aquatic Ecosystems, 105 McGill Street, Montreal, Que, Canada H2Y 2E7
    Environ Res 98:89-99. 2005
    ....
  26. ncbi request reprint Alteration of the biochemical properties of female gonads and vitellins in the clam Mya arenaria at contaminated sites in the Saguenay Fjord
    F Gagne
    St Lawrence Centre, Environment Canada, Montreal, Quebec
    Mar Environ Res 53:295-310. 2002
    ..Vn from the municipal site were found to be highly phosphorylated, with higher levels of lipids and calcium. These results suggest that the chemical composition of the gonads and Vn are altered in contaminated sites...
  27. ncbi request reprint Effects of municipal effluents on serotonin and dopamine levels in the freshwater mussel Elliptio complanata
    F Gagne
    St Lawrence Centre, Environment Canada, 105 McGill Street, Montreal, Quebec, Canada H2Y 2E7
    Comp Biochem Physiol C Toxicol Pharmacol 136:117-25. 2003
    ..Chemicals acting through E2 receptor-mediated pathways and serotonin receptors are likely to cause the observed effects...
  28. ncbi request reprint Endocrine disruption and health effects of caged mussels, Elliptio complanata, placed downstream from a primary-treated municipal effluent plume for 1 year
    F Gagne
    St Lawrence Centre, Research on Aquatic Ecosystems, Environment Canada, 105 McGill, Montreal, Quebec, Canada H2Y 2E7
    Comp Biochem Physiol C Toxicol Pharmacol 138:33-44. 2004
    ..Mussels exposed for 1 year display a complex but characteristic pattern of responses that could lead to harmful health effects including neuroendocrine disruption of reproduction...
  29. ncbi request reprint Shell protein characteristics and vitellogenin-like proteins in brine shrimp Artemia franciscana exposed to municipal effluent and 20-hydroxyecdysone
    F Gagne
    St Lawrence Centre, Environment Canada, 105 McGill St, Montreal, Quebec, Canada H2Y 2E7
    Comp Biochem Physiol C Toxicol Pharmacol 138:515-22. 2004
    ..The municipal effluent appears to contain ecdysial-like chemicals that are capable of producing changes in shell protein composition that are similar to 20HE...
  30. ncbi request reprint Occurrence of pharmaceutical products in a municipal effluent and toxicity to rainbow trout (Oncorhynchus mykiss) hepatocytes
    F Gagne
    St Lawrence Centre, Environment Canada, 105 McGill St, Montreal, QC, Canada H2Y 2E7
    Ecotoxicol Environ Saf 64:329-36. 2006
    ..These products have the potential to produce a toxic response in aquatic organisms and the above biomarkers were shown to respond readily to PPCPs in aquatic organisms...
  31. ncbi request reprint Sex alteration in soft-shell clams (Mya arenaria) in an intertidal zone of the Saint Lawrence river (Quebec, Canada)
    F Gagne
    Centre Saint Laurent, Environnement Canada, 105 Mc Gill, Montreal, Que, Canada H2Y 2E7
    Comp Biochem Physiol C Toxicol Pharmacol 134:189-98. 2003
    ....
  32. ncbi request reprint Biomarker study of a municipal effluent dispersion plume in two species of freshwater mussels
    F Gagne
    St Lawrence Centre, Environment Canada, 105 McGill Street, 7th Floor, Montreal, Quebec, Canada H2Y 2E7
    Environ Toxicol 17:149-59. 2002
    ..complanata only) were diminished. The exposure of mussels to surface waters contaminated by a municipal effluent led to many stress responses, depending on both the tissues and the species being examined...
  33. ncbi request reprint Health status of Mya arenaria bivalves collected from contaminated sites in Canada (Saguenay Fjord) and Denmark (Odense Fjord) during their reproductive period
    F Gagne
    Environment Canada, St Lawrence Centre, 105 McGill Street, 7th Floor, Montreal, Que, Canada H2Y 2E7
    Ecotoxicol Environ Saf 64:348-61. 2006
    ..We conclude that the health status of M. arenaria clams at these contaminated sites is compromised, with obvious disruption of reproductive activity...
  34. ncbi request reprint Inflammatory properties of municipal effluents to Elliptio complanata mussels--lack of effects from anti-inflammatory drugs
    F Gagne
    Environment Canada, St Lawrence Centre, 105 McGill Street, Montreal, Quebec, Canada H2Y 2E7
    Comp Biochem Physiol C Toxicol Pharmacol 141:332-7. 2005
    ..Besides their known estrogenic and serotonergic properties, municipal effluents appear to elicit a state similar to inflammation in freshwater mussels...
  35. ncbi request reprint Effects of selected pharmaceutical products on phagocytic activity in Elliptio complanata mussels
    F Gagne
    Environment Canada, St Lawrence Centre, Montreal, Quebec
    Comp Biochem Physiol C Toxicol Pharmacol 143:179-86. 2006
    ..The data suggest that PPCPs have the potential to cause adverse effects on the immune system of bivalves...
  36. ncbi request reprint Evidence of coprostanol estrogenicity to the freshwater mussel Elliptio complanata
    F Gagne
    St Lawrence Centre, 7th Floor, 105 McGill Street, Montreal, Quebec, Canada H2Y 2E7
    Environ Pollut 115:97-106. 2001
    ..One of these compounds appears to be the C17 oxidation product of coprostanol, whose polarity is similar to that of estradiol. The results present evidence that coprostanol is estrogenic to freshwater mussels...
  37. ncbi request reprint Neuroendocrine disruption and health effects in Elliptio complanata mussels exposed to aeration lagoons for wastewater treatment
    F Gagne
    Aquatic Ecosystem Protection Research Division, Water Science and Technology, Environment Canada, 105 McGill, Montreal, Que, Canada H2Y 2E7
    Chemosphere 68:731-43. 2007
    ..Aeration lagoons for the treatment of domestic wastewaters are toxic, estrogenic and disrupt the metabolism of monoamines and COX in freshwater mussels...
  38. doi request reprint Bioavailability and immunotoxicity of silver nanoparticles to the freshwater mussel Elliptio complanata
    F Gagne
    a Emerging Methods Section, Aquatic Contaminants Research Division, Water Science and Technology Directorate, Environment Canada, Montreal, Quebec, Canada
    J Toxicol Environ Health A 76:767-77. 2013
    ..Data also demonstrated that nAg are bioavailable for mussels where the immune system is a target during early exposure to nanoparticles. ..
  39. ncbi request reprint Molluscan shellfish biomarker study of the Quebec, Canada, Saguenay Fjord with the soft-shell clam, Mya arenaria
    C Blaise
    St Lawrence Centre, Environment Canada, 105 McGill Street, Montreal, Quebec, Canada H2Y 2E7
    Environ Toxicol 17:170-86. 2002
    ..In short, this study has provided evidence that clam populations in the Saguenay Fjord are impacted by multiple sources of contamination whose effects can be modulated by reproduction...
  40. doi request reprint Evidence of neuroendocrine disruption in freshwater mussels exposed to municipal wastewaters
    F Gagne
    Fluvial Ecosystem Research, Environment Canada, Montreal, Que, Canada
    Sci Total Environ 409:3711-8. 2011
    ..We conclude that the continuous exposure of freshwater mussels to municipal wastewater effluents leads to neuroendrocinal alterations and to oxidative stress...
  41. doi request reprint An in-situ study of the impacts of urban wastewater on the immune and reproductive systems of the freshwater mussel Elliptio complanata
    B Bouchard
    Environment Canada, Fluvial Ecosystem Research, 105 McGill, 7th Floor, Montreal, Quebec, Canada
    Comp Biochem Physiol C Toxicol Pharmacol 150:132-40. 2009
    ..Both Vtg and immune status are impacted by urban effluents and should be considered when using the Vtg biomarker to search for the presence of (xeno)estrogens in contaminated environments...
  42. doi request reprint Immunocompetence and alterations in hepatic gene expression in rainbow trout exposed to CdS/CdTe quantum dots
    F Gagne
    Fluvial Ecosystem Research, Aquatic Ecosystem Research Protection, Water Science and Technology, Environment Canada, Montreal, Quebec, Canada
    J Environ Monit 12:1556-65. 2010
    ..The present study revealed that each form of Cd produced a different pattern of gene expression and lowered fish immunocompetence...
  43. doi request reprint Occurrence of the transgenic corn cry1Ab gene in freshwater mussels (Elliptio complanata) near corn fields: evidence of exposure by bacterial ingestion
    M Douville
    Fluvial Ecosystem Research, Environment Canada, Montreal, Quebec, Canada
    Ecotoxicol Environ Saf 72:17-25. 2009
    ..The transgene was found at two out of six surface water samples and in one sediment sample. The study revealed that exposure to transgenic corn cry1Ab gene in mussels seems to proceed by ingestion of microorganisms during feeding...
  44. ncbi request reprint Neuroendocrine disruption in Mya arenaria clams during gametogenesis at sites under pollution stress
    F Gagne
    River Ecosystem Research, Aquatic Ecosystem Protection Division, Environment Canada, 105 McGill Street, Montreal, Que, Canada H2Y 2E7
    Mar Environ Res 64:87-107. 2007
    ..We conclude that the effects of pollution compromise the clams' health status and that the initiation of gametogenesis in environments contaminated by municipal wastewaters or harbours contributes to the toxic effects of pollution...
  45. doi request reprint Ecotoxicological impacts of effluents generated by oil sands bitumen extraction and oil sands lixiviation on Pseudokirchneriella subcapitata
    T Debenest
    Environment Canada, Fluvial Ecosystem Research, 105 McGill Street, Montreal, Quebec H2Y 2E7, Canada
    Aquat Toxicol 112:83-91. 2012
    ..To our knowledge, our study highlights the first evidence of physiological effects of OSPW and OSLW on microalgae...
  46. ncbi request reprint Delayed gametogenesis of Mya arenaria in the Saguenay fjord (Canada): a consequence of endocrine disruptors?
    S Gauthier-Clerc
    Institut des Sciences de la Mer de Rimouski, Universite du Quebec a Rimouski, 310 allee des Ursulines, Rimouski, G5L 3A1, Quebec, Canada
    Comp Biochem Physiol C Toxicol Pharmacol 131:457-67. 2002
    ..A persistent dysfunction of a vitellogenic process is suspected to be due to the exposure to anti-estrogenic contaminants...
  47. ncbi request reprint Occurrence of compounds estrogenic to freshwater mussels in surface waters in an urban area
    F Gagne
    St Lawrence Centre, Environment Canada, 105 McGill Street, Montreal, Quebec, Canada H2Y 2E7
    Environ Toxicol 16:260-8. 2001
    ..Thus, the environmental inputs of estrogens are likely to be associated with human sewage and pesticide products...
  48. doi request reprint DNA integrity assessment in hemocytes of soft-shell clams (Mya arenaria) in the Saguenay Fjord (Québec, Canada)
    T Debenest
    Fluvial Ecosystem Research, Environment Canada, 105 McGill, Montreal, QC H2Y 2E7, Canada
    Environ Sci Pollut Res Int 20:621-9. 2013
    ..Water conductivity was also related to reduced MN frequency and DNA content variation, indicating that, in addition to the effects of pollution, the gradual dilution of saltwater could compromise mussel health...
  49. doi request reprint Short-term physiological effects of a xenobiotic mixture on the freshwater mussel Elliptio complanata exposed to municipal effluents
    E Farcy
    Environment Canada, Fluvial Ecosystem Research, 105 McGill Avenue, Montreal, Quebec, Canada H2Y 2E7
    Environ Res 111:1096-106. 2011
    ..complanata, as observed with the modulation of immune response and induction of detoxification metabolism...
  50. doi request reprint In vitro immunotoxicity of environmentally representative antibiotics to the freshwater mussel Elliptio complanata
    M Gust
    Fluvial Ecosystem Research, Environment Canada, Montreal, Quebec, Canada
    Environ Pollut 169:50-8. 2012
    ..In conclusion, the data revealed that the removal of fine particles and microorganisms from municipal effluents can alter the toxic nature of the effluent that is closely associated with the cumulative effects of antibiotics...
  51. ncbi request reprint Effects of commercial microbial products on the immune system of Elliptio complanata mussels
    F Gagne
    St Lawrence Center, Environment Canada, Montreal, Quebec
    Bull Environ Contam Toxicol 76:848-54. 2006
  52. doi request reprint Ecotoxicity of a brominated flame retardant (tetrabromobisphenol A) and its derivatives to aquatic organisms
    T Debenest
    Environment Canada, Fluvial Ecosystem Research, Montreal, Quebec, Canada H2Y 2E7
    Comp Biochem Physiol C Toxicol Pharmacol 152:407-12. 2010
    ..Its toxicity was also significantly higher than the other compounds barring B(3)BPA when tested with the micro-crustacean test...
  53. ncbi request reprint Occurrence of alkylphenol polyethoxylates in the St. Lawrence River and their bioconcentration by mussels (Elliptio complanata)
    H Sabik
    St Lawrence Centre, Environment Canada, 105 McGill Street, 7th Floor, Montreal, Quebec, Canada H2Y 2E7
    Chemosphere 51:349-56. 2003
    ..Likewise, the slight, but not significant, bioconcentration of certain alkylphenol polyethoxylates (AP(n)EO) in the mussels was more noticeable at the downstream site than at the upstream site...
  54. ncbi request reprint Immunocompetence of bivalve hemocytes as evaluated by a miniaturized phagocytosis assay
    C Blaise
    St Lawrence Centre, Environment Canada, 105 McGill Street, Montreal, Quebec, Canada H2Y 2E7
    Environ Toxicol 17:160-9. 2002
    ..It appears that both immunosuppressive and immunostimulative effects are likely to occur in the field and that responses will be influenced by the type and intensity of contaminants at play...
  55. ncbi request reprint Occurrence and persistence of Bacillus thuringiensis (Bt) and transgenic Bt corn cry1Ab gene from an aquatic environment
    M Douville
    Environment Canada, St Lawrence Centre, 105 McGill Street, Montreal, Que, Canada H2Y 2E7
    Ecotoxicol Environ Saf 66:195-203. 2007
    ..83;P=0.04). The data indicate that DNA from Bt corn and Bt were persistent in aquatic environments and were detected in rivers draining farming areas...
  56. doi request reprint Ecotoxicity of selected nano-materials to aquatic organisms
    C Blaise
    Environment Canada, 105 McGill Street, Montreal, Quebec, Canada, H2Y 2E7
    Environ Toxicol 23:591-8. 2008
    ..This initial investigation suggests that chemicals emerging from nanotechnology may pose a risk to aquatic life in water column and sediment compartments and that further studies on their adverse effects are to be encouraged...
  57. ncbi request reprint Immunotoxicological effects of an activated-sludge-treated effluent on rainbow trout (Oncorhynchus mykiss)
    C Muller
    INRS Institut Armand Frappier, Laval, Quebec, Canada
    Comp Biochem Physiol C Toxicol Pharmacol 150:390-4. 2009
    ....
  58. doi request reprint Impacts of municipal wastewater oxidative treatments: changes in metal physical speciation and bioavailability
    C Gagnon
    Science and Technology Branch, Environment Canada, 105 McGill St, 7th Floor, Montreal, Quebec H2Y 2E7, Canada Electronic address
    Chemosphere 97:86-91. 2014
    ..Despite this disadvantage, ozonation still represents a great choice of treatment considering the overall environmental benefits. ..
  59. doi request reprint Effects of short-term exposure to environmentally relevant concentrations of different pharmaceutical mixtures on the immune response of the pond snail Lymnaea stagnalis
    M Gust
    IRSTEA, UR MAEP, Laboratoire d Ecotoxicologie, 3 bis quai Chauveau, 69009 Lyon, France
    Sci Total Environ 445:210-8. 2013
    ..stagnalis...
  60. doi request reprint Immunotoxicity of surface waters contaminated by municipal effluents to the snail Lymnaea stagnalis
    M Gust
    IRSTEA, UR MAEP, Laboratoire d Ecotoxicologie, Lyon, France
    Aquat Toxicol 126:393-403. 2013
    ..The data revealed that genes involved in oxidative stress were strongly involved with immunocompetence and that the resulting immune responses were influenced both by the bacterial and pollutant loadings of the effluent...
  61. pmc Changes in metallothionein levels in freshwater mussels exposed to urban wastewaters: effects from exposure to heavy metals?
    F Gagne
    St Lawrence Centre, Environment Canada, 105 McGill, Montreal, Quebec, Canada H2Y 2E7
    Biomark Insights 2:107-16. 2007
    ....
  62. ncbi request reprint Genotoxic potential of several naphthenic acids and a synthetic oil sands process-affected water in rainbow trout (Oncorhynchus mykiss)
    E Lacaze
    Emerging Methods Section, Environment Canada, 105 McGill St, Montreal, H2Y2E7 Quebec, Canada INRA, USC IGH, LEHNA UMR 5023, Université de Lyon ENTPE, F 69518, Vaulx en Velin, France Electronic address
    Aquat Toxicol 152:291-9. 2014
    ..Further research is needed to explore the relationships between the chemical structure of NAs and their genotoxicity in the light of the distribution of NAs in fresh OSPW samples as well as in surface waters. ..