Francine M Ducharme

Summary

Country: Canada

Publications

  1. ncbi Diagnosis, management, and prognosis of preschool wheeze
    Francine M Ducharme
    Clinical Research and Knowledge Transfer on Childhood Asthma Unit, Research Centre, Sainte Justine University Health Centre, Montreal, QC, Canada Department of Paediatrics, University of Montreal, Montreal, QC, Canada Department of Social and Preventive Medicine, University of Montreal, Montreal, QC, Canada Electronic address
    Lancet 383:1593-604. 2014
  2. pmc Best strategies to implement clinical pathways in an emergency department setting: study protocol for a cluster randomized controlled trial
    Mona Jabbour
    Division of Emergency Medicine, Children s Hospital of Eastern Ontario, Ottawa, Canada
    Implement Sci 8:55. 2013
  3. doi Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults
    Bhupendrasinh F Chauhan
    Clinical Research Unit on Childhood Asthma, Research Centre, CHU Sainte Justine, Montreal, Canada
    Cochrane Database Syst Rev 2:CD009611. 2013
  4. doi Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults
    Bhupendrasinh F Chauhan
    Clinical Research Unit on Childhood Asthma, Research Centre, CHU Sainte Justine, Montreal, Canada
    Cochrane Database Syst Rev 12:CD009611. 2012
  5. ncbi High physician adherence to phenotype-specific asthma guidelines, but large variability in phenotype assessment in children
    Francine M Ducharme
    Department of Paediatrics, University of Montreal, Research Centre, CHU Ste Justine, Montreal, Quebec, Canada
    Curr Med Res Opin 28:1561-70. 2012
  6. ncbi Clinical effectiveness of inhaled corticosteroids versus montelukast in children with asthma: prescription patterns and patient adherence as key factors
    Francine M Ducharme
    Department of Pediatrics, University of Montreal, Montreal, Quebec, Canada
    Curr Med Res Opin 28:111-9. 2012
  7. pmc Do pediatric emergency departments pose a risk of infection?
    Caroline Quach
    Infectious Diseases Division, Department of Pediatrics, The Montreal Children s Hospital, McGill University Health Center, 2300 Tupper Street, Montreal, H3H 1P3, Canada
    BMC Pediatr 11:2. 2011
  8. doi Written action plan in pediatric emergency room improves asthma prescribing, adherence, and control
    Francine M Ducharme
    Department of Pediatrics, University of Montreal, Montreal, Quebec, Canada
    Am J Respir Crit Care Med 183:195-203. 2011
  9. doi Preemptive use of high-dose fluticasone for virus-induced wheezing in young children
    Francine M Ducharme
    Applied Clinical Research Unit, Centre hospitalier universitaire Sainte Justine, and the Department of Pediatrics, University of Montreal, Montreal, Quebec, Canada
    N Engl J Med 360:339-53. 2009
  10. pmc Two for one: a self-management plan coupled with a prescription sheet for children with asthma
    Francine M Ducharme
    Clinical Research on Chilhood Asthma, University of Montreal, Canada
    Can Respir J 15:347-54. 2008

Collaborators

Detail Information

Publications40

  1. ncbi Diagnosis, management, and prognosis of preschool wheeze
    Francine M Ducharme
    Clinical Research and Knowledge Transfer on Childhood Asthma Unit, Research Centre, Sainte Justine University Health Centre, Montreal, QC, Canada Department of Paediatrics, University of Montreal, Montreal, QC, Canada Department of Social and Preventive Medicine, University of Montreal, Montreal, QC, Canada Electronic address
    Lancet 383:1593-604. 2014
    ..The role of leukotriene receptor antagonist is less clear. Interventions to modify the short-term and long-term outcomes of preschool wheeze should be a research priority. ..
  2. pmc Best strategies to implement clinical pathways in an emergency department setting: study protocol for a cluster randomized controlled trial
    Mona Jabbour
    Division of Emergency Medicine, Children s Hospital of Eastern Ontario, Ottawa, Canada
    Implement Sci 8:55. 2013
    ..This study will seek to develop and comprehensively evaluate best strategies for effective local implementation of externally developed expert clinical pathways...
  3. doi Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults
    Bhupendrasinh F Chauhan
    Clinical Research Unit on Childhood Asthma, Research Centre, CHU Sainte Justine, Montreal, Canada
    Cochrane Database Syst Rev 2:CD009611. 2013
    ..However, often, ICS are used intermittently by patients or recommended by physicians to be used only at the onset of exacerbations...
  4. doi Intermittent versus daily inhaled corticosteroids for persistent asthma in children and adults
    Bhupendrasinh F Chauhan
    Clinical Research Unit on Childhood Asthma, Research Centre, CHU Sainte Justine, Montreal, Canada
    Cochrane Database Syst Rev 12:CD009611. 2012
    ..Yet often, ICS are used intermittently by patients or recommended by physicians to be used only at the onset of exacerbations...
  5. ncbi High physician adherence to phenotype-specific asthma guidelines, but large variability in phenotype assessment in children
    Francine M Ducharme
    Department of Paediatrics, University of Montreal, Research Centre, CHU Ste Justine, Montreal, Quebec, Canada
    Curr Med Res Opin 28:1561-70. 2012
    ..The implementation of international pediatric asthma guidelines hinges on the distinction between intermittent and persistent phenotypes and the prescription of recommended phenotype-specific pharmacotherapy...
  6. ncbi Clinical effectiveness of inhaled corticosteroids versus montelukast in children with asthma: prescription patterns and patient adherence as key factors
    Francine M Ducharme
    Department of Pediatrics, University of Montreal, Montreal, Quebec, Canada
    Curr Med Res Opin 28:111-9. 2012
    ..To examine the real-life effectiveness of inhaled corticosteroids (ICS) versus leukotriene receptor antagonists (LTRA) monotherapy in children with mild or moderate asthma...
  7. pmc Do pediatric emergency departments pose a risk of infection?
    Caroline Quach
    Infectious Diseases Division, Department of Pediatrics, The Montreal Children s Hospital, McGill University Health Center, 2300 Tupper Street, Montreal, H3H 1P3, Canada
    BMC Pediatr 11:2. 2011
    ..Our objective was to determine the risk of infection associated to a pediatric Emergency Department (ED) visit and the predictors of infection in children aged 5 years and less...
  8. doi Written action plan in pediatric emergency room improves asthma prescribing, adherence, and control
    Francine M Ducharme
    Department of Pediatrics, University of Montreal, Montreal, Quebec, Canada
    Am J Respir Crit Care Med 183:195-203. 2011
    ..An acute-care visit for asthma often signals a management failure. Although a written action plan is effective when combined with self-management education and regular medical review, its independent value remains controversial...
  9. doi Preemptive use of high-dose fluticasone for virus-induced wheezing in young children
    Francine M Ducharme
    Applied Clinical Research Unit, Centre hospitalier universitaire Sainte Justine, and the Department of Pediatrics, University of Montreal, Montreal, Quebec, Canada
    N Engl J Med 360:339-53. 2009
    ..We examined the efficacy and safety of preemptive treatment with high-dose fluticasone in reducing the severity of recurrent virus-induced wheezing in children...
  10. pmc Two for one: a self-management plan coupled with a prescription sheet for children with asthma
    Francine M Ducharme
    Clinical Research on Chilhood Asthma, University of Montreal, Canada
    Can Respir J 15:347-54. 2008
    ..Despite strong recommendations in the asthma guidelines, the use of written self-management plans remains low among asthmatic patients...
  11. doi Steroid responsiveness and wheezing phenotypes
    Francine M Ducharme
    Departments of Pediatrics and of Social Preventive Medicine, University of Montreal, Montreal, Quebec, Canada
    Paediatr Respir Rev 12:170-6. 2011
    ..The clinician should carefully confirm the diagnosis of asthma and ascertain the phenotype to select appropriate phenotype-specific therapy...
  12. doi Relationship between changes in inhaled corticosteroid use and markers of uncontrolled asthma during pregnancy
    Lucie Blais
    University of Montreal, Montreal, Quebec, Canada
    Pharmacotherapy 32:202-9. 2012
    ..To describe changes in inhaled corticosteroid use during pregnancy and markers of uncontrolled asthma, and to evaluate the association between them...
  13. doi Early administration of systemic corticosteroids reduces hospital admission rates for children with moderate and severe asthma exacerbation
    Sanjit K Bhogal
    Department of Epidemiology, Biostatistics and Occupational Health, Faculty of Medicine, McGill University, Montreal, Quebec, Canada
    Ann Emerg Med 60:84-91.e3. 2012
    ..We examine the effect of early (within 60 minutes [SD 15 minutes] of triage) versus delayed (>75 minutes) administration of systemic corticosteroids on health outcomes...
  14. doi The Pediatric Respiratory Assessment Measure: a valid clinical score for assessing acute asthma severity from toddlers to teenagers
    Francine M Ducharme
    Clinical Research Group on Childhood Asthma, Department of Pediatrics, McGill University Health Centre, Montreal, Quebec, Canada
    J Pediatr 152:476-80, 480.e1. 2008
    ..To determine the performance characteristics of the Preschool Respiratory Assessment Measure (PRAM) in preschool and school-aged children with acute asthma...
  15. doi Effect of maternal moderate to severe asthma on perinatal outcomes
    Faranak Firoozi
    Universite de Montreal, Quebec, Canada
    Respir Med 104:1278-87. 2010
    ..In our study, we investigated the effect that the severity of asthma during pregnancy has on the risk of a small for gestational age (SGA) infant, low birth weight (LBW), and preterm birth...
  16. ncbi Safety and effectiveness of long-acting inhaled beta-agonist bronchodilators when taken with inhaled corticosteroids
    Pierre Ernst
    McGill University, Montreal, Quebec, Canada
    Ann Intern Med 145:692-4. 2006
    ....
  17. doi Inhaled corticosteroids vs. leukotriene-receptor antagonists and asthma exacerbations in children
    Lucie Blais
    Universite de Montreal, Faculte de Pharmacie, C P 6128, Succursale Centre Ville, Montreal, Quebec, Canada H3C 3J7
    Respir Med 105:846-55. 2011
    ..Compared to inhaled corticosteroids (ICS), better use of leukotriene-receptor antagonists (LTRA) may lead to a greater reduction in exacerbations among asthmatic children in real-life settings...
  18. ncbi Acute asthma in children and adolescents: should inhaled anticholinergics be added to beta(2)-agonists?
    Laurie H Plotnick
    Montreal Children s Hospital, McGill University Health Centre, Montreal, Quebec, Canada
    Am J Respir Med 2:109-15. 2003
    ....
  19. ncbi Adult Asthma Consensus Guidelines update 2003
    Catherine Lemiere
    Universite de Montreal, Montreal, Quebec
    Can Respir J 11:9A-18A. 2004
    ..Since the last revision of the 1999 Canadian Asthma Consensus Report, important new studies have highlighted the need to incorporate new information into the asthma guidelines...
  20. doi Effect of fetal gender on maternal asthma exacerbations in pregnant asthmatic women
    Faranak Firoozi
    Universite de Montreal, Quebec, Canada
    Respir Med 103:144-51. 2009
    ..23 to 0.24). Based on the results, we conclude that fetal gender is unlikely to affect maternal asthma during pregnancy to the point where acute care and medications are more often required among women pregnant with a female fetus...
  21. ncbi Addition of long-acting beta2-agonists to inhaled steroids versus higher dose inhaled steroids in adults and children with persistent asthma
    Francine M Ducharme
    Research Centre, CHU Sainte Justine and the Department of Pediatrics, University of Montreal, 3175 Cote Sainte Catherine, Montreal, , Canada, H3T 1C5
    Cochrane Database Syst Rev 4:CD005533. 2010
    ..These trends raised concern about the safety of combination therapy in view of modest improvement in children under the age of 12 years...
  22. ncbi Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma
    Bhupendrasinh F Chauhan
    Clinical Research Unit on Childhood Asthma, Research Centre, CHU Sainte Justine, 3175, Cote Sainte Catherine, Montreal, Canada
    Cochrane Database Syst Rev 1:CD003137. 2014
    ..Long-acting beta2-agonists (LABA) and anti-leukotrienes (LTRA) are two treatment options that could be considered as add-on therapy to ICS...
  23. doi Addition of anti-leukotriene agents to inhaled corticosteroids in children with persistent asthma
    Bhupendrasinh F Chauhan
    Clinical Research Unit on Childhood Asthma, Research Centre, CHU Sainte Justine, 3175, Cote Sainte Catherine, Montreal, Canada
    Cochrane Database Syst Rev 10:CD009585. 2013
    ..In children with inadequate asthma control on low doses of ICS (step 2), asthma management guidelines recommend adding an anti-leukotriene agent to existing ICS as one of three therapeutic options to intensify therapy (step 3)...
  24. pmc Inhaled glucocorticoids versus leukotriene receptor antagonists as single agent asthma treatment: systematic review of current evidence
    Francine M Ducharme
    Department of Paediatrics, Montreal Children s Hospital, McGill University Health Centre, Montreal, Quebec, Canada
    BMJ 326:621. 2003
    ..To compare the safety and efficacy of anti-leukotrienes and inhaled glucocorticoids as monotherapy in people with asthma...
  25. ncbi Inhaled corticosteroids versus leukotriene antagonists as first-line therapy for asthma: a systematic review of current evidence
    Francine M Ducharme
    Department of Paediatrics, The Montreal Children s Hospital, McGill University Health Centre, 2300 Tupper Street Room C 538, Montreal, Quebec H3H 1P3, Canada
    Treat Respir Med 3:399-405. 2004
    ..In conclusion, the scientific evidence does not support the substitution of leukotriene receptor antagonists for low doses of inhaled corticosteroids, which should remain first-line therapy for asthma control...
  26. doi Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children
    Bhupendrasinh F Chauhan
    Clinical Research Unit of Childhood Asthma, Chu Sainte Justine hospital Research Centre, 3175, Cote Sainte Catherine, Montreal, Canada
    Cochrane Database Syst Rev 5:CD002314. 2012
    ..Anti-leukotrienes (5-lipoxygenase inhibitors and leukotriene receptors antagonists) serve as alternative monotherapy to inhaled corticosteroids (ICS) in the management of recurrent and/or chronic asthma in adults and children...
  27. ncbi Safety profile of frequent short courses of oral glucocorticoids in acute pediatric asthma: impact on bone metabolism, bone density, and adrenal function
    Francine M Ducharme
    Department of Pediatrics and Epidemiology, Montreal Children s Hospital, McGill University Health Centre, Montreal, Quebec, Canada
    Pediatrics 111:376-83. 2003
    ..Our study was designed to establish in children with asthma the safety profile of repeated short courses of oral glucocorticoids on bone mineralization and metabolism and adrenal function...
  28. ncbi The role of written action plans in childhood asthma
    Francine M Ducharme
    Department of Pediatrics, Montreal Children s Hospital, McGill University Health Centre, 2300 Tupper Street, Montreal, Canada
    Curr Opin Allergy Clin Immunol 8:177-88. 2008
    ..The aim of this article is to examine the evidence for the effectiveness of a written action plan as an important element of guided self-management and to identify key features associated with its effectiveness in children and adolescents...
  29. ncbi Impulse oscillometry: reference values in children 100 to 150 cm in height and 3 to 10 years of age
    Jennifer Frei
    Department of Pediatrics, Division of Respiratory Medicine, Montreal Children s Hospital, QC, Canada
    Chest 128:1266-73. 2005
    ....
  30. pmc Facilitators and solutions for practicing optimal guided asthma self-management: the physician perspective
    Alexandrine J Lamontagne
    Clinical Research and Knowledge Transfer Unit on Childhood Asthma, Research Centre, CHU Sainte Justine, Montreal, Quebec
    Can Respir J 20:285-93. 2013
    ..To identify key solutions that facilitate the prescription of long-term asthma controller and provision of written self-management plans by physicians...
  31. ncbi Intramuscular versus oral methylprednisolone in asthma
    Francine M Ducharme
    Department of Pediatrics, Montreal Children s Hospital, Montreal, Quebec, H3 h 1P3, Canada
    Lancet 364:2000-1. 2004
  32. ncbi The Asthma Quiz for Kidz: a validated tool to appreciate the level of asthma control in children
    Francine M Ducharme
    Department of Pediatrics Montreal Children s Hospital McGill University Health Centre, 2300 Tupper Street, Montreal, Quebec H3H 1P3, Canada
    Can Respir J 11:541-6. 2004
    ..There is an urgent need to bridge the large gap between optimal and observed asthma control among Canadian children...
  33. ncbi A randomized, controlled trial of the effectiveness of nebulized therapy with epinephrine compared with albuterol and saline in infants hospitalized for acute viral bronchiolitis
    Hema Patel
    Department of Pediatrics, McGill University Health Centre, Montreal, Quebec, Canada
    J Pediatr 141:818-24. 2002
    ..In previously well infants hospitalized with acute viral bronchiolitis, the effectiveness of repeated nebulized therapy with epinephrine (EPI) was compared with treatment with albuterol (ALB) or saline placebo (PLAC)...
  34. pmc Anti-leukotrienes as add-on therapy to inhaled glucocorticoids in patients with asthma: systematic review of current evidence
    Francine M Ducharme
    Department of Paediatrics, McGill University Health Centre, Montreal, QC H3H 1P3, Canada
    BMJ 324:1545. 2002
    ..To examine the evidence for the efficacy and glucocorticoid sparing effect of oral anti-leukotrienes taken daily as add-on therapy to inhaled glucocorticoids in patients with asthma...
  35. ncbi Inhaled corticosteroids in children with persistent asthma: dose-response effects on growth
    Aniela I Pruteanu
    Research Centre, CHU Sainte Justine and the Department of Pediatrics, University of Montreal, Montreal, Quebec, Canada
    Cochrane Database Syst Rev 7:CD009878. 2014
    ..Inhaled corticosteroids (ICS) are the first-line treatment for children with persistent asthma. Their potential for growth suppression remains a matter of concern for parents and physicians...
  36. ncbi Inhaled anticholinergics and short-acting beta2-agonists versus short-acting beta2-agonists alone for children with acute asthma in hospital
    Kevin Vézina
    Department of Pediatrics, CHU Sainte Justine, Montreal, QC, Canada
    Cochrane Database Syst Rev 7:CD010283. 2014
    ..It seems logical to assume a similar beneficial effect in children hospitalised for an acute asthma exacerbation...
  37. ncbi Addition to inhaled corticosteroids of long-acting beta2-agonists versus anti-leukotrienes for chronic asthma
    Francine M Ducharme
    Research Centre, CHU Sainte Justine and the Department of Pediatrics, University of Montreal, Room number 7939, 3175 Cote Sainte Catherine, Montreal, Quebec, Canada, H3T 1C5
    Cochrane Database Syst Rev 5:CD003137. 2011
    ..Long-acting beta(2)-agonists (LABA) or anti-leukotrienes (LTRA) are two treatment options that could be considered as add-on therapy to ICS...
  38. doi Prospective validation of the pediatric appendicitis score in a Canadian pediatric emergency department
    Maala Bhatt
    Division of Emergency Medicine, Montreal Children s Hospital, McGill University, Montreal, Quebec, Canada
    Acad Emerg Med 16:591-6. 2009
    ..The objective was to validate the score in a nonreferred population by emergency physicians (EPs)...
  39. ncbi Adenotonsillectomy improves sleep, breathing, and quality of life but not behavior
    Evelyn Constantin
    Department of Pediatrics, Montreal Children s Hospital, McGill University, Montreal, Canada
    J Pediatr 150:540-6, 546.e1. 2007
    ..To obtain parental perspectives on changes in sleep, breathing, quality of life (QOL), and neurobehavioral measures after adenotonsillectomy...