V A Wallace

Summary

Affiliation: Division of Immunology and Cancer Research
Country: Canada

Publications

  1. ncbi request reprint T lymphocyte development in p56lck deficient mice: allelic exclusion of the TcR beta locus is incomplete but thymocyte development is not restored by TcR beta or TcR alpha beta transgenes
    V A Wallace
    Amgen Institute, University of Toronto, Canada
    Eur J Immunol 25:1312-8. 1995
  2. pmc The induction of experimental autoimmune myocarditis in mice lacking CD4 or CD8 molecules [corrected]
    J M Penninger
    Amgen Research Institute, Ontario Cancer Institute, Toronto, Canada
    J Exp Med 178:1837-42. 1993
  3. ncbi request reprint Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum
    V A Wallace
    Ottawa General Hospital Research Institute, University of Ottawa Eye Institute, 501 Smyth Road, Ottawa, Ontario K1H 8L6, Canada
    Curr Biol 9:445-8. 1999
  4. ncbi request reprint A role for Sonic hedgehog in axon-to-astrocyte signalling in the rodent optic nerve
    V A Wallace
    Medical Research Council Developmental Neurobiology Programme, MRC Laboratory for Molecular Cell Biology and the Biology Department, University College London, London WC1E 6BT, UK
    Development 126:2901-9. 1999
  5. ncbi request reprint Expression of Sonic hedgehog and its putative role as a precursor cell mitogen in the developing mouse retina
    A M Jensen
    MRC Developmental Neurobiology Programme, University College London, UK
    Development 124:363-71. 1997
  6. pmc CD45RA and CD45RBhigh expression induced by thymic selection events
    V A Wallace
    Ontario Cancer Institute, Department of Medical Biophysics and Immunology, University of Toronto, Canada
    J Exp Med 176:1657-63. 1992
  7. ncbi request reprint Alterations in the level of CD45 surface expression affect the outcome of thymic selection
    V A Wallace
    Department of Medical Biophysics, University of Toronto, Ontario, Canada
    J Immunol 158:3205-14. 1997

Detail Information

Publications7

  1. ncbi request reprint T lymphocyte development in p56lck deficient mice: allelic exclusion of the TcR beta locus is incomplete but thymocyte development is not restored by TcR beta or TcR alpha beta transgenes
    V A Wallace
    Amgen Institute, University of Toronto, Canada
    Eur J Immunol 25:1312-8. 1995
    ....
  2. pmc The induction of experimental autoimmune myocarditis in mice lacking CD4 or CD8 molecules [corrected]
    J M Penninger
    Amgen Research Institute, Ontario Cancer Institute, Toronto, Canada
    J Exp Med 178:1837-42. 1993
    ..CD4+ and CD8+ cells regulate disease severity and these results may explain the occurrence of autoimmunity in CD4 immunodeficiencies...
  3. ncbi request reprint Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum
    V A Wallace
    Ottawa General Hospital Research Institute, University of Ottawa Eye Institute, 501 Smyth Road, Ottawa, Ontario K1H 8L6, Canada
    Curr Biol 9:445-8. 1999
    ..These results suggest that PC-derived Shh normally promotes the proliferation of granule neuron precursors in the EGL...
  4. ncbi request reprint A role for Sonic hedgehog in axon-to-astrocyte signalling in the rodent optic nerve
    V A Wallace
    Medical Research Council Developmental Neurobiology Programme, MRC Laboratory for Molecular Cell Biology and the Biology Department, University College London, London WC1E 6BT, UK
    Development 126:2901-9. 1999
    ..4) Astrocyte proliferation in the developing nerve is reduced by treatment with anti-Shh antibodies, suggesting that Shh normally helps stimulate this proliferation...
  5. ncbi request reprint Expression of Sonic hedgehog and its putative role as a precursor cell mitogen in the developing mouse retina
    A M Jensen
    MRC Developmental Neurobiology Programme, University College London, UK
    Development 124:363-71. 1997
    ..These findings suggest that hedgehog and patched are part of a conserved signalling pathway in retinal development in mammals and insects...
  6. pmc CD45RA and CD45RBhigh expression induced by thymic selection events
    V A Wallace
    Ontario Cancer Institute, Department of Medical Biophysics and Immunology, University of Toronto, Canada
    J Exp Med 176:1657-63. 1992
    ..These data suggest that modulation of CD45 isoform expression may be involved in thymic selection events...
  7. ncbi request reprint Alterations in the level of CD45 surface expression affect the outcome of thymic selection
    V A Wallace
    Department of Medical Biophysics, University of Toronto, Ontario, Canada
    J Immunol 158:3205-14. 1997
    ..These data demonstrate that changes in the expression level of the receptor protein tyrosine phosphatase CD45 can alter thymic selection...