E Dewailly

Summary

Country: Canada

Publications

  1. pmc Biomarker measurements in a coastal fish-eating population environmentally exposed to organochlorines
    Pierre Ayotte
    Unite de Recherche en Sante publique, Centre Hospitalier Universitaire de Quebec, Universite Laval, Quebec, Canada
    Environ Health Perspect 113:1318-24. 2005
  2. pmc Omega-3 fatty acids, polymorphisms and lipid related cardiovascular disease risk factors in the Inuit population
    Iwona Rudkowska
    Institute of Nutrition and Functional Foods INAF, Laval University, 2440, Boulevard Hochelaga, Quebec, QC, Canada
    Nutr Metab (Lond) 10:26. 2013
  3. pmc Evaluation of a public health intervention to lower mercury exposure from fish consumption in Bermuda
    Eric Dewailly
    Department of Population Health and Environment, Research Center CHUQ, Quebec, Canada
    PLoS ONE 7:e47388. 2012
  4. pmc Low serum magnesium concentrations are associated with a high prevalence of premature ventricular complexes in obese adults with type 2 diabetes
    Liana C Del Gobbo
    School of Dietetics and Human Nutrition, McGill University, 21, 111 Lakeshore Road, Ste Anne de Bellevue, Quebec, H9X 3V9, Canada
    Cardiovasc Diabetol 11:23. 2012
  5. pmc Perfluorinated compounds are related to breast cancer risk in Greenlandic Inuit: a case control study
    Eva C Bonefeld-Jorgensen
    Centre for Arctic Environmental Medicine, Department of Public Health, Aarhus University, Denmark
    Environ Health 10:88. 2011
  6. pmc Re-evaluation of blood mercury, lead and cadmium concentrations in the Inuit population of Nunavik (Québec): a cross-sectional study
    Julie Fontaine
    Unite de Recherche en Sante publique, Centre de Recherche du CHUL CHUQ, 2875 boul, Laurier, bureau 600, Québec Québec, G1V 2M2, Canada
    Environ Health 7:25. 2008
  7. pmc Plasma organochlorine concentrations and bone ultrasound measurements: a cross-sectional study in peri-and postmenopausal Inuit women from Greenland
    Suzanne Côté
    Unite de Recherche en Sante publique, Centre de Recherche du CHUL CHUQ, Quebec, QC, G1V 5B3, Canada
    Environ Health 5:33. 2006
  8. pmc Cardiac autonomic activity and blood pressure among Nunavik Inuit adults exposed to environmental mercury: a cross-sectional study
    Beatriz Valera
    Public Health Research Unit, 2875 boulevard Laurier, Edifice Delta 2, bureau 600, G1V 2M2, Quebec QC, Canada
    Environ Health 7:29. 2008
  9. pmc Strengthening integrated research and capacity development within the Caribbean region
    Martin Forde
    St, George s University, Grenada, W, I
    BMC Int Health Hum Rights 11:S7. 2011
  10. ncbi request reprint Fish consumption and blood lipids in three ethnic groups of Québec (Canada)
    Eric Dewailly
    Public Health Research Unit, CHUL Research Center, Centre Hospitalier Universitaire de Quebec, Sainte Foy, Quebec G1V 5B3, Canada
    Lipids 38:359-65. 2003

Detail Information

Publications98

  1. pmc Biomarker measurements in a coastal fish-eating population environmentally exposed to organochlorines
    Pierre Ayotte
    Unite de Recherche en Sante publique, Centre Hospitalier Universitaire de Quebec, Universite Laval, Quebec, Canada
    Environ Health Perspect 113:1318-24. 2005
    ..Our data are consistent with smoking-induced liver CYP1A2 activity altering heme metabolism and increasing the biotransformation of mono-ortho PCB congeners...
  2. pmc Omega-3 fatty acids, polymorphisms and lipid related cardiovascular disease risk factors in the Inuit population
    Iwona Rudkowska
    Institute of Nutrition and Functional Foods INAF, Laval University, 2440, Boulevard Hochelaga, Quebec, QC, Canada
    Nutr Metab (Lond) 10:26. 2013
    ....
  3. pmc Evaluation of a public health intervention to lower mercury exposure from fish consumption in Bermuda
    Eric Dewailly
    Department of Population Health and Environment, Research Center CHUQ, Quebec, Canada
    PLoS ONE 7:e47388. 2012
    ..To assess the efficacy of a public health intervention to reduce blood mercury (Hg) concentration levels in pregnant Bermudian women...
  4. pmc Low serum magnesium concentrations are associated with a high prevalence of premature ventricular complexes in obese adults with type 2 diabetes
    Liana C Del Gobbo
    School of Dietetics and Human Nutrition, McGill University, 21, 111 Lakeshore Road, Ste Anne de Bellevue, Quebec, H9X 3V9, Canada
    Cardiovasc Diabetol 11:23. 2012
    ..We thus hypothesized that serum magnesium (sMg) concentrations are inversely associated with the prevalence of PVC in adults at high cardiovascular risk...
  5. pmc Perfluorinated compounds are related to breast cancer risk in Greenlandic Inuit: a case control study
    Eva C Bonefeld-Jorgensen
    Centre for Arctic Environmental Medicine, Department of Public Health, Aarhus University, Denmark
    Environ Health 10:88. 2011
    ..This study aimed at evaluating the association between serum levels of POPs/PFCs in Greenlandic Inuit BC cases and their controls, and whether the combined POP related effect on nuclear hormone receptors affect BC risk...
  6. pmc Re-evaluation of blood mercury, lead and cadmium concentrations in the Inuit population of Nunavik (Québec): a cross-sectional study
    Julie Fontaine
    Unite de Recherche en Sante publique, Centre de Recherche du CHUL CHUQ, 2875 boul, Laurier, bureau 600, Québec Québec, G1V 2M2, Canada
    Environ Health 7:25. 2008
    ....
  7. pmc Plasma organochlorine concentrations and bone ultrasound measurements: a cross-sectional study in peri-and postmenopausal Inuit women from Greenland
    Suzanne Côté
    Unite de Recherche en Sante publique, Centre de Recherche du CHUL CHUQ, Quebec, QC, G1V 5B3, Canada
    Environ Health 5:33. 2006
    ..We hypothesized that this exposure might be related to bone characteristics that are altered in osteoporosis, because hormone deficiency is a known risk factor for the disease...
  8. pmc Cardiac autonomic activity and blood pressure among Nunavik Inuit adults exposed to environmental mercury: a cross-sectional study
    Beatriz Valera
    Public Health Research Unit, 2875 boulevard Laurier, Edifice Delta 2, bureau 600, G1V 2M2, Quebec QC, Canada
    Environ Health 7:29. 2008
    ..MeHg has been suggested to affect BP in adults and children while the influence on HRV has only been studied in children. We aimed to assess the impact of MeHg levels on HRV and BP in Inuit adults from Nunavik...
  9. pmc Strengthening integrated research and capacity development within the Caribbean region
    Martin Forde
    St, George s University, Grenada, W, I
    BMC Int Health Hum Rights 11:S7. 2011
    ....
  10. ncbi request reprint Fish consumption and blood lipids in three ethnic groups of Québec (Canada)
    Eric Dewailly
    Public Health Research Unit, CHUL Research Center, Centre Hospitalier Universitaire de Quebec, Sainte Foy, Quebec G1V 5B3, Canada
    Lipids 38:359-65. 2003
    ..Our results indicate that increased consumption of fish as a source of n-3 fatty acids is beneficially associated with levels of HDL cholesterol and triacylglycerols...
  11. doi request reprint Vitamin A intoxication from reef fish liver consumption in Bermuda
    E Dewailly
    Centre de Recherche du Centre Hospitalier Universitaire de Québec, 2875 Boulevarde Laurier, Quebec, Canada
    J Food Prot 74:1581-3. 2011
    ..Large variations in concentrations were observed between specimens and between species. The angling population and (especially) pregnant women should be advised of this potential health threat...
  12. doi request reprint Balancing the risks and the benefits of local fish consumption in Bermuda
    E Dewailly
    Public Health Research Unit, Laval University Research Centre CHUL CHUQ, Quebec, Canada
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 25:1328-38. 2008
    ..03 to 3.3 microg g(-1) and that it is possible for at-risk groups such as pregnant women to make informed choices concerning fish consumption, e.g. maximizing fish species rich in nutrients and low in mercury...
  13. pmc Influence of mercury exposure on blood pressure, resting heart rate and heart rate variability in French Polynesians: a cross-sectional study
    Beatriz Valera
    Axe Santé des Populations et Environnement, Centre de recherche du CHUQ, 2875 boulevard Laurier, Québec G1V 2M2, Canada
    Environ Health 10:99. 2011
    ..Populations which diet is rich in seafood are highly exposed to contaminants such as mercury, which could affect cardiovascular risk factors..
  14. ncbi request reprint Inuit are protected against prostate cancer
    Eric Dewailly
    Public Health Research Unit, CHUQ Laval University, Sainte Foy, Quebec, G1V 5B3 Canada
    Cancer Epidemiol Biomarkers Prev 12:926-7. 2003
    ..Our results suggest that in situ carcinoma is rare among Inuit and that their traditional diet, which is rich in omega-3 polyunsaturated fatty acids and selenium, may be an important protective factor...
  15. ncbi request reprint Risk and benefits from consuming salmon and trout: a Canadian perspective
    E Dewailly
    Unite de Recherche en Sante publique, Centre Hospitalier Universitaire de Québec CHUQ CHUL and Université Laval, Quebec, QC, Canada G1V 2M2
    Food Chem Toxicol 45:1343-8. 2007
    ....
  16. ncbi request reprint Influence of n-3 fatty acids on cardiac autonomic activity among Nunavik Inuit adults
    Beatriz Valera
    Axe Santé des Populations et Environnement, Centre de recherche du CHUQ, Quebec, QC G1V 2M2, Canada
    Int J Circumpolar Health 70:6-18. 2011
    ..The study assessed the impact of n-3 PUFAs (Docosahexaenoic [DHA] and Eicosapentaenoic acid [EPA]) on resting HR and HRV among Nunavik Inuit adults considering mercury and other potential confounders...
  17. ncbi request reprint Fish consumption and health in French Polynesia
    Eric Dewailly
    Unite de Recherche en Sante publique, Centre de recherche du CHUQ, Universite Laval, 2875 boulevard Laurier, Edifice Delta 2, bureau 600, Quebec, Canada G1V 2M2
    Asia Pac J Clin Nutr 17:86-93. 2008
    ..Further work is ongoing to better substantiate public health nutritional policies...
  18. ncbi request reprint n-3 Fatty acids and cardiovascular disease risk factors among the Inuit of Nunavik
    E Dewailly
    Public Health Research Unit, CHUL Research Center, Centre Hospitalier Universitaire de Quebec, Ste Foy, Canada
    Am J Clin Nutr 74:464-73. 2001
    ..Inuit traditionally consume large amounts of marine foods rich in n-3 fatty acids. Evidence exists that n-3 fatty acids have beneficial effects on key risk factors for cardiovascular disease...
  19. ncbi request reprint Relations between n-3 fatty acid status and cardiovascular disease risk factors among Quebecers
    E Dewailly E
    Public Health Research Unit and the Lipid Research Center, CHUL Research Center, Centre Hospitalier Universitaire de Quebec, Ste Foy, Canada
    Am J Clin Nutr 74:603-11. 2001
    ..Epidemiologic evidence shows an inverse relation between fish consumption and death from ischemic heart disease. This beneficial effect is attributed to n-3 fatty acids...
  20. ncbi request reprint High fish consumption in French Polynesia and prenatal exposure to metals and nutrients
    Eric Dewailly
    Universite Laval, Centre de Recherche du CHUL CHUQ, Quebec, Canada
    Asia Pac J Clin Nutr 17:461-70. 2008
    ..Although selenium and omega-3 fatty acids may counteract mercury toxicity, informing pregnant women on both the mercury and nutrient content of local fish species is important...
  21. ncbi request reprint Cardiovascular disease risk factors and n-3 fatty acid status in the adult population of James Bay Cree
    Eric Dewailly
    Public Health Research Unit, CHUL Research Center, Centre Hospitalier Universitaire de Quebec, Quebec, Canada
    Am J Clin Nutr 76:85-92. 2002
    ..Fish oils rich in n-3 fatty acids may have a protective effect against cardiovascular disease (CVD) risk factors...
  22. doi request reprint Alteration of infant attention and activity by polychlorinated biphenyls: unravelling critical windows of susceptibility using physiologically based pharmacokinetic modeling
    M A Verner
    Departement des Sciences Biologiques, TOXEN, Universite du Quebec a Montreal, Montreal, Quebec, Canada
    Neurotoxicology 31:424-31. 2010
    ..Simulated infant toxicokinetic profiles for the first year of life revealed windows of susceptibility during which PCBs may impair infant attention and activity...
  23. ncbi request reprint Seroprevalence of seven zoonotic infections in Nunavik, Quebec (Canada)
    V Messier
    Unite de Recherche en Sante publique, Axe Santé des Populations et Environnement, CHUQ CHUL, Quebec, QC, Canada
    Zoonoses Public Health 59:107-17. 2012
    ..Further studies are needed to better understand the mechanisms for transmission of zoonotic infections and their potential reservoirs in Nunavik...
  24. doi request reprint The relation of environmental contaminants exposure to behavioral indicators in Inuit preschoolers in Arctic Quebec
    P Plusquellec
    CHUQ Research Center, Quebec, QC, Canada
    Neurotoxicology 31:17-25. 2010
    ..No association was found with Hg exposure. These data corroborated those from previous Pb cohort studies and revealed an association between prenatal PCBs exposure and emotional outcomes in preschoolers...
  25. doi request reprint Dietary sodium intake deleteriously affects blood pressure in a normotensive population
    M L Chateau-Degat
    Axe santé des populations et environnementale, Centre de Recherche du CHUL, Quebec, QC, Canada
    Eur J Clin Nutr 66:533-5. 2012
    ..05). In a normotensive population, BP shows a linear relationship with DSI. Our results emphasize the potent deleterious impact of DSI on BP...
  26. pmc Susceptibility to infections and immune status in Inuit infants exposed to organochlorines
    E Dewailly
    Unite de Recherche en Sante publique, Centre Hospitalier Universitaire de Quebec, Pavillon CHUL, Beauport, Quebec, Canada
    Environ Health Perspect 108:205-11. 2000
    ..We conclude that prenatal organochlorine exposure could be a risk factor for acute otitis media in Inuit infants...
  27. doi request reprint Plasma omega-3 and psychological distress among Nunavik Inuit (Canada)
    Michel Lucas
    Public Health Research Unit, Laval University Medical Research Centre CHUQ, Sainte Foy, Quebec, Canada
    Psychiatry Res 167:266-78. 2009
    ..Our findings suggest that marine n-3 may play a role in PD among Inuit women. The gender difference observed in our analysis must be examined more carefully in future studies...
  28. doi request reprint Environmental mercury exposure and blood pressure among Nunavik Inuit adults
    Beatriz Valera
    Axe Santé des Populations et Environnement, Centre de Recherche du Centre Hospitalier Universitaire de Québec, Quebec, Canada
    Hypertension 54:981-6. 2009
    ..96; P=0.069). In conclusion, mercury is associated with increasing BP and pulse pressure among Nunavik Inuit adults after considering the effect of fish nutrients (n-3 fatty acids and selenium) and other confounders...
  29. pmc The relation of low-level prenatal lead exposure to behavioral indicators of attention in Inuit infants in Arctic Quebec
    P Plusquellec
    Public Health Research Unit, CHUQ Research Center CHUL, Sainte Foy, Quebec, Canada G1V 2M2
    Neurotoxicol Teratol 29:527-37. 2007
    ....
  30. ncbi request reprint Environmental contaminants and redox status of coenzyme Q10 and vitamin E in Inuit from Nunavik
    Marie Claire Bélanger
    Québec Lipid Research Centre, CHUL Research Centre, Centre Hospitalier Universitaire de Quebec, Quebec City, Quebec, Canada G1V 4G2
    Metabolism 57:927-33. 2008
    ..However, despite robust blood antioxidant defenses, the unusually elevated ubiquinone-10 to CoQ10(total) ratio (0.21 +/- 0.11) suggests some form of oxidative stress of unknown origin...
  31. pmc Temporal trends of organochlorine concentrations in umbilical cord blood of newborns from the lower north shore of the St. Lawrence river (Québec, Canada)
    Frederic Dallaire
    Public Health Research Unit, Laval University Medical Center, and Laval University, Quebec, Canada
    Environ Health Perspect 110:835-8. 2002
    ..These results show that prenatal exposure to persistent OCs has declined significantly between 1993 and 2000 in this population...
  32. pmc Time trends of persistent organic pollutants and heavy metals in umbilical cord blood of Inuit infants born in Nunavik (Québec, Canada) between 1994 and 2001
    Frederic Dallaire
    Public Health Research Unit, Laval University Medical Center CHUL CHUQ, and Laval University, Quebec City, Quebec, Canada
    Environ Health Perspect 111:1660-4. 2003
    ..The decreases observed could be explained by a decrease in food contamination, by changes in dietary habits, or, most likely, by a combination of both...
  33. ncbi request reprint Very high concentrations of n-3 fatty acids in peri- and postmenopausal Inuit women from Greenland
    S Cote
    Public Health Research Unit, CHUL Research Center, Centre Hospitalier Universitaire de Quebec, Ste Foy, Canada
    Int J Circumpolar Health 63:298-301. 2004
    ....
  34. doi request reprint Assessment of microbiological quality of drinking water from household tanks in Bermuda
    B Levesque
    Institut National de Sante Publique du Quebec, Quebec, QC, Canada
    Can J Microbiol 54:495-500. 2008
    ..If rainwater collection from roofs is the most efficient mean for providing freshwater to Bermudians, it must not be considered a source of high quality drinking water because of the high levels of microbial contamination...
  35. pmc Environmental exposure to polychlorinated biphenyls and placental CYP1A1 activity in Inuit women from northern Québec
    Daria Pereg
    Département de Biologie médicale, Faculte de Medecine, Université Laval et Unité de recherche en santé et environnement, Ste Foy, Quebec, Canada
    Environ Health Perspect 110:607-12. 2002
    ..We conclude that dietary exposure to PCBs in Inuit women from Nunavik does not significantly influence EROD activity in the placenta, implicating tobacco smoking as the major modulating factor...
  36. pmc In vitro activation of cord blood mononuclear cells and cytokine production in a remote coastal population exposed to organochlorines and methyl mercury
    Houda Bilrha
    Rheumatology Immunology Research Unit, CHUQ Laval University Medical Center, Quebec City, Quebec, Canada
    Environ Health Perspect 111:1952-7. 2003
    ....
  37. pmc Assessment of pre- and postnatal exposure to polychlorinated biphenyls: lessons from the Inuit Cohort Study
    Pierre Ayotte
    Department of Social and Preventive Medicine, Laval University and Public Health Research Unit, CHUQ Laval University Medical Centre, Quebec, Quebec, Canada
    Environ Health Perspect 111:1253-8. 2003
    ....
  38. ncbi request reprint Prenatal exposure to methylmercury and PCBs affects distinct stages of information processing: an event-related potential study with Inuit children
    Olivier Boucher
    Ecole de Psychologie, Universite Laval, Quebec, Canada
    Neurotoxicology 31:373-84. 2010
    ..These effects seem to be mitigated in children who are breast-fed for a more extended period...
  39. doi request reprint Plasma n-3 fatty acids and psychological distress in aboriginal Cree Indians (Canada)
    Michel Lucas
    Public Health Research Unit, Laval University Medical Research Centre, Sainte Foy, Quebec, Canada
    Public Health Nutr 12:2343-51. 2009
    ..To examine the relationship between psychological distress (PD) and plasma n-3 long-chain (LC) PUFA, i.e. EPA, docosapentaenoic acid (DPAn-3) and DHA...
  40. doi request reprint Is marine mammal fat or fish intake most strongly associated with omega-3 blood levels among the Nunavik Inuit?
    M Lucas
    Axe Santé des Populations et Environnement, Centre Hospitalier de l Université Laval CHUL CHUQ, Delta Building 2 Office 600, 2875 Laurier Blvd, 6th Floor, Que, Canada G1V 2M2
    Prostaglandins Leukot Essent Fatty Acids 83:143-50. 2010
    ..Our study indicates that marine mammal fat intake is more important than fish in accounting for RBC n-3 LC-PUFA levels among the Nunavik Inuit...
  41. doi request reprint Seroprevalence of Toxoplasma gondii among Nunavik Inuit (Canada)
    V Messier
    Unite de Recherche en Sante publique, CHUQ CHUL, Quebec, QC, Canada
    Zoonoses Public Health 56:188-97. 2009
    ..These results raise important questions about T. gondii transmission in Nunavik including possible links between terrestrial and marine cycles...
  42. ncbi request reprint Evaluation of the health risk associated with exposure to chloroform in indoor swimming pools
    B Levesque
    Unite de Recherche en Sante publique, Centre Hospitalier Universitaire de Quebec, Beauport, Canada
    J Toxicol Environ Health A 61:225-43. 2000
    ..Data indicate that the safety margin is therefore very large, for competitive swimmers as well as for leisure swimmers...
  43. doi request reprint Omega-3 fatty acids and risk of dementia: the Canadian Study of Health and Aging
    Edeltraut Kröger
    Centre d Excellence sur le Vieillissement de Quebec, Unite de Recherche sur le Vieillissement, Centre de recherche FRSQ du Centre hospitalier affilié universitaire de Québec, Quebec, Canada
    Am J Clin Nutr 90:184-92. 2009
    ..Fish is the main dietary source of n-3 PUFAs and is sometimes contaminated with mercury. This neurotoxicant may modify the association with dementia...
  44. ncbi request reprint Vitamin A concentration in umbilical cord blood of infants from three separate regions of the province of Québec (Canada)
    Frederic Dallaire
    Public Health Research Unit, Laval University Medical Center CHUL CHUQ, and Laval University, Sainte Foy, Quebec
    Can J Public Health 94:386-90. 2003
    ..This study was conducted to evaluate the prevalence of blood vitamin A deficiency in newborns from 3 distinct populations of the province of Québec...
  45. pmc Effect of prenatal exposure to polychlorinated biphenyls on incidence of acute respiratory infections in preschool Inuit children
    Frederic Dallaire
    Public Health Research Unit, Laval University Medical Center Centre Hospitalier Universitaire de Québec, Quebec City, Quebec, Canada
    Environ Health Perspect 114:1301-5. 2006
    ..We set out to assess whether environmental prenatal exposure to polychlorinated biphenyls (PCBs) is associated with incidence of acute respiratory infections in preschool Inuit children...
  46. ncbi request reprint Gestational age and birth weight in relation to n-3 fatty acids among Inuit (Canada)
    Michel Lucas
    Public Health Research Unit, Laval University Medical Research Centre, Centre Hospitalier Universitaire de Quebec, Quebec G1V 5B3, Canada
    Lipids 39:617-26. 2004
    ..In this seafood-eating population, an increase in the proportion of n-3 HUFA (of the total HUFA), measured in umbilical cord plasma phospholipids, was associated with a significantly longer GA...
  47. ncbi request reprint Increase in plasma pollutant levels in response to weight loss is associated with the reduction of fasting insulin levels in men but not in women
    P Imbeault
    Department of Social and Preventive Medicine, Laval University, Ste Foy, Quebec, Canada
    Metabolism 51:482-6. 2002
    ..Further studies are needed to verify whether these findings are causally related...
  48. pmc Monitoring of umbilical cord blood lead levels and sources assessment among the Inuit
    B Levesque
    Unite de Recherche en Sante publique, Centre de Recherche du CHUL CHUQ, 945, avenue Wolfe, Sainte Foy, Quebec G1V 5B3, Canada
    Occup Environ Med 60:693-5. 2003
    ..Lead shot ammunition can be a major and preventable source of human exposure to lead...
  49. doi request reprint Comparison of diagnostic criteria of the metabolic syndrome in 3 ethnic groups of Canada
    Marie Ludivine Chateau-Degat
    Centre for Indigenous Peoples Nutrition and Environment and School of Dietetics and Human Nutrition, McGill University, Ste Anne de Bellevue, Quebec, Canada H9X 3V9
    Metabolism 57:1526-32. 2008
    ..001). These 3 unique population-based samples suggest that abdominal obesity does not have a similar deleterious impact according to ethnicity, suggesting the need for an ethnic-based MetS definition...
  50. ncbi request reprint Obesity risks: towards an emerging Inuit pattern
    Marie Ludivine Chateau-Degat
    School of Dietetics and Human Nutrition and Centre for Indigenous Peoples Nutrition and Environment CINE, McGill University, Ste Anne de Bellevue, Canada
    Int J Circumpolar Health 70:166-77. 2011
    ..Study design. Cross-sectional study...
  51. doi request reprint n-3 Fatty acid intake from marine food products among Quebecers: comparison to worldwide recommendations
    Michel Lucas
    Lucie and André Chagnon Chair for the Teaching of an Integrated Approach in Prevention, Laval University, Saint François d Assise Hospital CHUQ, Quebec, QC, Canada
    Public Health Nutr 13:63-70. 2010
    ..To quantify marine food product consumption and EPA + DHA intake among Quebecers, and to compare the results with the most recent recommendations...
  52. ncbi request reprint Erythrocyte n-3 is inversely correlated with serious psychological distress among the Inuit: data from the Nunavik health survey
    Michel Lucas
    Axe Santé des Populations et Environnement, Centre Hospitalier de l Université Laval CHUL CHUQ, Ste Foy QC G1V 2M2, Canada
    J Am Coll Nutr 29:211-21. 2010
    ..The present study examined the relationship between red blood cell (RBC) n-3 and n-6 and serious psychological distress (SPD)...
  53. pmc The relation of lead neurotoxicity to the event-related potential P3b component in Inuit children from arctic Québec
    Olivier Boucher
    Ecole de Psychologie, Universite Laval, Quebec, Canada
    Neurotoxicology 30:1070-7. 2009
    ..This study strengthens the arguments for reducing sources of Pb exposure in Nunavik and for lowering the blood Pb concentrations considered "acceptable" in governmental policies...
  54. ncbi request reprint Determinants of plasma concentrations of perfluorooctanesulfonate and brominated organic compounds in Nunavik Inuit adults (Canada)
    Renee Dallaire
    Public Health Research Unit, Centre Hospitalier Universitaire de Québec CHUL, Quebec, Quebec, Canada
    Environ Sci Technol 43:5130-6. 2009
    ..In conclusion, we found that the remote geographical location and traditional lifestyle of the Nunavik Inuit population do not protect them against exposure to emerging POPs, particularly PFOS...
  55. ncbi request reprint Hypertension among the Inuit from Nunavik: should we expect an increase because of obesity?
    Marie Ludivine Chateau-Degat
    School of Dietetics and Human Nutrition, McGill University, Ste Anne de Bellevue, Canada
    Int J Circumpolar Health 69:361-72. 2010
    ..This study aimed to assess the exact prevalence of HTN in Nunavik Inuit and to examine its association with other major risk factors of cardiovascular disease...
  56. pmc Cardiovascular burden and related risk factors among Nunavik (Quebec) Inuit: insights from baseline findings in the circumpolar Inuit health in transition cohort study
    Marie Ludivine Chateau-Degat
    School of Dietetics and Human Nutrition, McGill University, Montreal, Canada
    Can J Cardiol 26:190-6. 2010
    ..However, actual sociocultural transition and related major, modifiable risk factors have scarcely been quantified in the Inuit population. Such knowledge is extremely valuable in terms of public health intervention...
  57. doi request reprint Association between trans-fatty acids in erythrocytes and pro-atherogenic lipid profiles among Canadian Inuit of Nunavik: possible influences of sex and age
    Emilie Counil
    Public Health Research Unit, CHUL Research Centre, Quebec, QC, Canada
    Br J Nutr 102:766-76. 2009
    ..The differential associations reported in pre- and postmenopausal women need to be reproduced in other populations and in experimental studies addressing the influence of sex hormones in response to dietary fats...
  58. pmc Acute infections and environmental exposure to organochlorines in Inuit infants from Nunavik
    Frederic Dallaire
    Department of Social and Preventive Medicine, Laval University, and Public Health Research Unit, CHUQ Laval University Medical Center, 945 Wolfe Street, Sainte Foy, Quebec G1V 5B3, Canada
    Environ Health Perspect 112:1359-65. 2004
    ..05). No association was found when postnatal exposure was considered. These results show a possible association between prenatal exposure to OCs and acute infections early in life in this Inuit population...
  59. ncbi request reprint Impact of waist circumference on the relationship between blood pressure and insulin: the Quebec Health Survey
    Paul Poirier
    Quebec Heart and Lungs Institute, Laval Hospital Research Center, Quebec, Canada
    Hypertension 45:363-7. 2005
    ..3%; P<0.0001). These results suggest that the documented association between obesity, fasting insulin, insulin sensitivity, and blood pressure is largely explained by concomitant variation in WC...
  60. ncbi request reprint Cancer risk associated with household exposure to chloroform
    Benoît Lévesque
    Unite de Recherche en Sante publique, Centre Hospitalier Universitaire de Quebec, Beauport, Canada
    J Toxicol Environ Health A 65:489-502. 2002
    ..Data indicate that for this range of exposure the safety margin appears therefore considerable with respect to the potential carcinogenic effect of household exposure to CHCl3...
  61. ncbi request reprint Levels of cadmium in kidney and liver tissues among a Canadian population (province of Québec)
    J L Benedetti
    Centre de Toxicologie du Quebec, Centre Hospitalier Universitaire de Quebec, Pavillon CHUL, Sainte Foy, Canada
    J Toxicol Environ Health A 56:145-63. 1999
    ..25 microg/g and a maximum of 100.61 microg/g. Mean concentrations of cadmium in kidneys increased with age, reaching a plateau in the group 50 to 59 yr (29.49 microg/g), and falling slowly thereafter...
  62. ncbi request reprint Omega-3 fatty acids and risk of cognitive impairment and dementia
    Danielle Laurin
    Laval University Geriatric Research Unit, Quebec, QC, Canada
    J Alzheimers Dis 5:315-22. 2003
    ..03) concentrations were found in dementia cases. These findings do not support the hypothesis that omega-3 polyunsaturated fatty acids play a protective role in cognitive function and dementia...
  63. doi request reprint Determinants of AhR-mediated transcriptional activity induced by plasma extracts from Nunavik Inuit adults
    Thierry C M Medehouenou
    Axe de recherche en santé des populations et environnementale, Centre de recherche du Centre hospitalier universitaire de Québec and Université Laval, 2875 boulevard Laurier, Quebec, QC, Canada
    Chemosphere 80:75-82. 2010
    ..AhR-mediated transcriptional activity measures may prove useful in investigating possible associations between exposure to AhR agonists and adverse health effects in this indigenous population...
  64. pmc Thyroid hormone levels of pregnant inuit women and their infants exposed to environmental contaminants
    Renee Dallaire
    Public Health Research Unit, Centre Hospitalier Universitaire de Québec CHUL, Quebec City, Quebec, Canada
    Environ Health Perspect 117:1014-20. 2009
    ..Prenatal exposure to some of them, such as polychlorinated biphenyls (PCBs), has also been associated with adverse neurodevelopmental effects in infants...
  65. ncbi request reprint Portrait of outpatient visits and hospitalizations for acute infections in Nunavik preschool children
    Frederic Dallaire
    Department of Social and Preventive Medicine, Laval University, and Public Health Research Unit, CHUQ Laval University Medical Center, Quebec, Canada
    Can J Public Health 97:362-8. 2006
    ..Inuit children from around the world are burdened by a high rate of infectious diseases. The objective of this study was to evaluate the incidence rate of infections in Inuit preschool children from Nunavik (Northern Québec)...
  66. ncbi request reprint Temporal trends and epidemiological aspects of ciguatera in French Polynesia: a 10-year analysis
    Marie Ludivine Chateau-Degat
    Public Health Research Unit, Laval University Medical Research Center CHUQ, Quebec, Canada
    Trop Med Int Health 12:485-92. 2007
    ..The purpose of this study was to report the temporal trends of the incidence of ciguatera poisoning from 1992 to 2001 in French Polynesia...
  67. doi request reprint Persistent organic pollutants and transthyretin-bound thyroxin in plasma of Inuit women of childbearing age
    Y Audet-Delage
    Axe Santé des populations et pratiques optimales en santé, Centre de Recherche du CHU de Québec, Quebec, QC, Canada
    Environ Sci Technol 47:13086-92. 2013
    ..The possibility of increased delivery of these compounds to the developing brain requires further investigation. ..
  68. doi request reprint Impact of mercury exposure on blood pressure and cardiac autonomic activity among Cree adults (James Bay, Quebec, Canada)
    B Valera
    Axe Santé des Populations et Environnement, Centre de recherche du CHUQ, Quebec QC, Canada
    Environ Res 111:1265-70. 2011
    ....
  69. ncbi request reprint Neonatal vitamin A deficiency and its impact on acute respiratory infections among preschool Inuit children
    Cynthia Cameron
    Public Health Research Unit, Laval University Medical Center CHUL, Quebec City, Quebec
    Can J Public Health 99:102-6. 2008
    ..To assess if vitamin A concentration in umbilical cord blood is associated with incidence and severity of respiratory infections in preschool Inuit children from Nunavik (Québec, Canada)...
  70. doi request reprint Effects of prenatal exposure to organochlorines on thyroid hormone status in newborns from two remote coastal regions in Québec, Canada
    Renee Dallaire
    Public Health Research Unit, Laval University Medical Research Centre Centre Hospitalier, Universitaire de Quebec, Quebec City, Quebec, Canada
    Environ Res 108:387-92. 2008
    ..One of the mechanisms by which PCBs might interfere with neurodevelopment is a deficit in thyroid hormone (TH) concentrations...
  71. doi request reprint Effects of perfluorooctanesulfonate exposure on plasma lipid levels in the Inuit population of Nunavik (Northern Quebec)
    Marie Ludivine Chateau-Degat
    Axe santé des populations et environnementale, Research center of the Centre hospitalier universitaire de Québec and Université Laval, Quebec, QC, Canada G1V 2M2
    Environ Res 110:710-7. 2010
    ..The Inuit of Nunavik are exposed to environmental contaminants through the consumption of fish and game. This diet is also a source of omega3-polyunsaturated fatty acids (n-3 PUFAs) that are known to lower plasma triacylglycerols...
  72. pmc Thyroid function and plasma concentrations of polyhalogenated compounds in Inuit adults
    Renee Dallaire
    Public Health Research Unit, Centre Hospitalier Universitaire de Québec CHUL, 2875 boulevard Laurier Edifice Delta, Quebec, Canada
    Environ Health Perspect 117:1380-6. 2009
    ..So far, epidemiologic studies have focused on the potential effect of a small number of them, namely, polychlorinated biphenyls (PCBs) and some organochlorines (OCs), without paying attention to other important PHCs...
  73. ncbi request reprint Neurologic signs of ciguatera disease: evidence of their persistence
    M L Chateau-Degat
    Public Health Research Unit, Laval University Medical Research Center, Sainte Foy, Quebec, Canada
    Am J Trop Med Hyg 77:1170-5. 2007
    ..Our results support the existence of neurologic impairments of CD and suggest their persistence for at least two months after onset...
  74. doi request reprint Seasonal mercury exposure and oxidant-antioxidant status of James Bay sport fishermen
    Marie Claire Bélanger
    Québec Lipid Research Centre, CHUL Research Centre, Centre Hospitalier Universitaire de Quebec, Quebec City, Quebec, Canada G1V 4G2
    Metabolism 57:630-6. 2008
    ..The beneficial effects of seasonal fishing activity and fish consumption on cardiovascular health may suppress detrimental effects of concomitant moderate methylmercury exposure...
  75. ncbi request reprint Reduced seminal parameters associated with environmental DDT exposure and p,p'-DDE concentrations in men in Chiapas, Mexico: a cross-sectional study
    Christiaan De Jager
    Centre de Recherche en Biologie de la Reproduction, Departement des Sciences Animales, Universite Laval, Quebec City, Quebec, Canada
    J Androl 27:16-27. 2006
    ..J Androl. 1998;19:5). This is the first epidemiological study demonstrating effects after nonoccupational exposures to DDT. Based on these findings, the effect of DDT on male reproductive health should not be ignored...
  76. ncbi request reprint Fatty acid composition of wild and farmed Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss)
    Carole Blanchet
    Public Health Research Unit, Centre Hospitalier Universitaire de Quebec CHUQ, Canada
    Lipids 40:529-31. 2005
    ..Total n-3 and n-6 PUFA were significantly higher in farmed AS than in wild AS. Farmed RT contained more fat and less n-3 PUFA than wild RT. Our results show that farmed salmonids provide high levels of n-3 HUFA to consumers...
  77. ncbi request reprint Prevalence of chronic symptoms of ciguatera disease in French Polynesian adults
    Marie Ludivine Chateau-Degat
    Public Health Research Unit, Laval University Medical Research Center, CHUL, CHUQ, Quebec, Canada
    Am J Trop Med Hyg 77:842-6. 2007
    ..001). Our findings suggest that several symptoms observed in the acute phase of the disease are still experienced 15 days after onset. This supports previous observations based on isolated case reports...
  78. pmc Vitamin D receptor polymorphisms (FokI, BsmI) and breast cancer risk: association replication in two case-control studies within French Canadian population
    Marc Sinotte
    Unité de recherche en santé des populations, Centre Hospitalier Affilie Universitaire De Quebec, 1050 Chemin Sainte Foy, Quebec, Quebec, Canada G1S 4L8
    Endocr Relat Cancer 15:975-83. 2008
    ..They also suggest that variability in observed associations between VDR FokI and breast cancer from different studies may partly be explained by the proportion of study subjects with a family history of breast cancer...
  79. ncbi request reprint Blood pressure among the Inuit (Eskimo) populations in the Arctic
    Peter Bjerregaard
    National Institute of Public Health, Svanemollevej 25, DK 2100 Copenhagen, Denmark
    Scand J Public Health 31:92-9. 2003
    ..This study compared the blood pressure among the major Inuit population groups with other populations and examined the associations with factors like age, gender, obesity and smoking...
  80. ncbi request reprint Prevalence of metabolic alterations predictive of cardiovascular disease risk in the Québec population
    Carla Scarsella
    Quebec Heart Institute, Laval Hospital Research Centre, Sainte Foy, Canada
    Can J Cardiol 19:51-7. 2003
    ..Objective: To quantify the prevalence of metabolic alterations predictive of an increased risk of CVD in a representative sample of the Québec population...
  81. pmc Comparison of polychlorinated biphenyl levels across studies of human neurodevelopment
    Matthew P Longnecker
    Epidemiology Branch, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 111:65-70. 2003
    ..S. studies or recent Dutch, German, and northern Québec studies. Our results will facilitate a direct comparison of the findings on PCBs and neurodevelopment when they are published for all 10 studies...
  82. ncbi request reprint Indicators of ocean and human health
    Eric Dewailly
    Laval University, Quebec
    Can J Public Health 93:S34-8. 2002
    ..Such tools would provide early detection of potential environmental threats, and enhance the ability to prevent human illness...
  83. ncbi request reprint Prevalence of 'hypertriglyceridemic waist' in men who participated in the Quebec Health Survey: association with atherogenic and diabetogenic metabolic risk factors
    Isabelle Lemieux
    Quebec Heart Institute, Laval Hospital Research Center, Laval University, Sainte Foy, Quebec
    Can J Cardiol 18:725-32. 2002
    ..0 mmol/L or higher) in men has been shown to be associated with this atherogenic metabolic triad, with a probability of more than 80%...
  84. pmc Pentachlorophenol and hydroxylated polychlorinated biphenyl metabolites in umbilical cord plasma of neonates from coastal populations in Québec
    Courtney D Sandau
    Centre for Analytical and Environmental Chemistry, Department of Chemistry, Carleton University, Ottawa, Ontario, Canada
    Environ Health Perspect 110:411-7. 2002
    ..Further studies are needed to examine the effects of chlorinated phenolic compounds on thyroid hormone status in newborns...
  85. ncbi request reprint Plasma concentrations of polychlorinated biphenyls and the risk of breast cancer: a congener-specific analysis
    Alain Demers
    Department of Preventive Oncology and Epidemiology, CancerCare Manitoba, Winnipeg, Manitoba, Canada
    Am J Epidemiol 155:629-35. 2002
    ..Alternatively, the results may be explained by differences between cases and controls regarding metabolic pathways involved in the biotransformation of both mono-ortho PCBs and estrogens...
  86. ncbi request reprint Cord blood lymphocyte functions in newborns from a remote maritime population exposed to organochlorines and methylmercury
    Marthe Belles-Isles
    Unité de recherche en rhumatologie immunologie, Centre Hospitalier Universitaire de Québec CHUL, Ste Foy, Canada
    J Toxicol Environ Health A 65:165-82. 2002
    ..Epidemiological studies are needed to determine the relevance of these alterations in predicting detrimental health effects in the developing child...
  87. doi request reprint Beneficial effects of a polyunsaturated fatty acid on infant development: evidence from the inuit of arctic Quebec
    Joseph L Jacobson
    Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, Michigan, USA
    J Pediatr 152:356-64. 2008
    ....
  88. ncbi request reprint Dietary contaminants and oxidative stress in Inuit of Nunavik
    Marie Claire Bélanger
    Québec Lipid Research Center, CHUL Research Center CHUQ, Sainte Foy, Quebec, Canada G1V 4G2
    Metabolism 55:989-95. 2006
    ..This study suggests that, in adult Inuit, contaminated traditional diet seems to have no direct oxidative effects on molecules involved in oxidative stress...
  89. ncbi request reprint Exposure of a Cree population living near mine tailings in northern Quebec (Canada) to metals and metalloids
    Dominique Bussières
    Institut National de Sante Publique du Quebec, Canada
    Arch Environ Health 59:732-41. 2004
    ..43). Blood cadmium increased with age and smoking (R2 = 0.61). No influence of mine residues was observed among residents of Oujé-Bougoumou, but lifestyle exposure associations were noted for both communities...
  90. ncbi request reprint Alterations of visual evoked potentials in preschool Inuit children exposed to methylmercury and polychlorinated biphenyls from a marine diet
    Dave Saint-Amour
    Departement d Ophtalmologie, CHU Sainte Justine, 3175, Cote Sainte Catherine, Montreal, Que, Canada H3T 1C5
    Neurotoxicology 27:567-78. 2006
    ..e. at the preschool age. Our findings suggest that VEP can be used as a valuable tool to assess the developmental neurotoxicity of environmental contaminants in fish-eating populations...
  91. ncbi request reprint Nonoccupational determinants of plasma DDT and p,p'-DDE in men from Chiapas, Mexico
    Albino Barraza-Villarreal
    Center for Population Health Research, National Institute of Public Health, Cuernavaca, Morelos, Mexico
    Arch Environ Health 59:42-9. 2004
    ..High levels of chlorinated pesticides were found despite being banned in Mexico for agricultural and public health use. Findings demonstrate the role of antimalarial campaigns as a major contributing factor for high DDT plasma levels...
  92. ncbi request reprint Neuromotor functions in Inuit preschool children exposed to Pb, PCBs, and Hg
    Christine Després
    Cognitive Neuroscience Center, University of Quebec at Montreal, Montreal, Quebec, C P 8888 Succ Centre Ville, Canada H3C 3P8
    Neurotoxicol Teratol 27:245-57. 2005
    ..Tremor amplitude was related to blood Hg concentrations at testing time, which corroborate an effect already reported among adults...
  93. pmc Prevalence of obesity and its metabolic correlates among the circumpolar inuit in 3 countries
    T Kue Young
    Department of Public Health Sciences, University of Toronto, Toronto, Ontario, Canada
    Am J Public Health 97:691-5. 2007
    ..We investigated the prevalence of obesity and the metabolic correlates of different levels of body mass index (BMI) and waist circumference among the Inuit in 3 countries...
  94. ncbi request reprint Fatty acid compositions of serum phospholipids of postmenopausal women: a comparison between Greenland Inuit and Canadians before and after supplementation with fish oil
    Ken D Stark
    Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ontario N1G 2W1, Canada
    Nutrition 18:627-30. 2002
    ....
  95. pmc Indicators of ocean health and human health: developing a research and monitoring framework
    Anthony Knap
    Bermuda Biological Station for Research, Inc, St George s, Bermuda
    Environ Health Perspect 110:839-45. 2002
    ..The tight connection between research and monitoring is essential to develop such an indicator-based effort...
  96. ncbi request reprint Indigenous health in the Arctic: an overview of the circumpolar Inuit population
    Peter Bjerregaard
    Centre for Health Research in Greenland, National Institute of Public Health, Copenhagen, Denmark
    Scand J Public Health 32:390-5. 2004
    ..Lifestyle changes, social change, and changes in society and the environment are major determinants of health among the Inuit...
  97. ncbi request reprint Seroprevalence of zoonoses in a Cree community (Canada)
    Benoît Lévesque
    Institut National de Sante Publique du Quebec, Direction des Risques Biologiques, Environnementaux et Occupationnels, Quebec City, Quebec, Canada G1V 5B3
    Diagn Microbiol Infect Dis 59:283-6. 2007
    ..Overall, seropositivity was related to fishing, hunting, and trapping activities. Physicians should be aware of these infections in this population, particularly Q fever, tularemia, and leptospirosis...
  98. ncbi request reprint Fat, fishing patterns, and health among the Bardi people of north Western Australia
    Philippe Max Rouja
    Center for Ocean and Human Health, Bermuda Biological Station for Research Inc, St George s, Bermuda
    Lipids 38:399-405. 2003
    ..The Bardi model provides important insights into the nature of human-environment interaction and expands our understanding of the role that warmer-water fisheries can play in human health...