R Delage

Summary

Country: Canada

Publications

  1. ncbi request reprint All patients with persistent polyclonal B cell lymphocytosis present Bcl-2/Ig gene rearrangements
    R Delage
    Centre d Hématologie et d Immunologie Clinique, Hopital du St Sacrement, Universite Laval, Ste Foy, Quebec, Canada
    Leuk Lymphoma 31:567-74. 1998
  2. ncbi request reprint Persistent polyclonal B-cell lymphocytosis: further evidence for a genetic disorder associated with B-cell abnormalities
    R Delage
    Centre d Hématologie et d Immunologie Clinique, Hopital du St Sacrement, Laval University, 1050 Chemin Ste Foy, Quebec, Canada
    Br J Haematol 114:666-70. 2001
  3. ncbi request reprint Lack of CD40-dependent B-cell proliferation in B lymphocytes isolated from patients with persistent polyclonal B-cell lymphocytosis
    M M Loembé
    CREFSIP, Départment de Biochimie and Microbiologie, Universite Laval, and Centre d hématologie et d immunologie clinique, CHA, Quebec, Canada
    Br J Haematol 113:699-705. 2001
  4. ncbi request reprint Evidence of a founder effect for the protein C gene 3363 inserted C mutation in thrombophilic pedigrees of French origin
    P Couture
    Department of Internal Medicine, CHUL Research Center, CHUQ, Quebec, Canada
    Thromb Haemost 86:1000-6. 2001
  5. ncbi request reprint Type I protein C deficiency in French Canadians: evidence of a founder effect and association of specific protein C gene mutations with plasma protein C levels
    P Couture
    Laboratory of Molecular Endocrinology, CHUL Research Center, Quebec, Canada
    Thromb Haemost 80:551-6. 1998
  6. ncbi request reprint The impact of UGT1A8, UGT1A9, and UGT2B7 genetic polymorphisms on the pharmacokinetic profile of mycophenolic acid after a single oral dose in healthy volunteers
    E Levesque
    Research Center, CHUL Research Center and Faculty of Pharmacy, Laval University, Quebec, Canada
    Clin Pharmacol Ther 81:392-400. 2007

Collaborators

Detail Information

Publications6

  1. ncbi request reprint All patients with persistent polyclonal B cell lymphocytosis present Bcl-2/Ig gene rearrangements
    R Delage
    Centre d Hématologie et d Immunologie Clinique, Hopital du St Sacrement, Universite Laval, Ste Foy, Quebec, Canada
    Leuk Lymphoma 31:567-74. 1998
    ..In addition, Bcl-2 protein expression was increased. Our findings, along with the clinical features of PPBL, make this disorder an exceptional model for the study of B-cell homeostasis...
  2. ncbi request reprint Persistent polyclonal B-cell lymphocytosis: further evidence for a genetic disorder associated with B-cell abnormalities
    R Delage
    Centre d Hématologie et d Immunologie Clinique, Hopital du St Sacrement, Laval University, 1050 Chemin Ste Foy, Quebec, Canada
    Br J Haematol 114:666-70. 2001
    ..We conclude that PPBL has a familial occurrence suggesting an underlying genetic defect. The development of the complete syndrome probably relies on unidentified additional co-factors...
  3. ncbi request reprint Lack of CD40-dependent B-cell proliferation in B lymphocytes isolated from patients with persistent polyclonal B-cell lymphocytosis
    M M Loembé
    CREFSIP, Départment de Biochimie and Microbiologie, Universite Laval, and Centre d hématologie et d immunologie clinique, CHA, Quebec, Canada
    Br J Haematol 113:699-705. 2001
    ....
  4. ncbi request reprint Evidence of a founder effect for the protein C gene 3363 inserted C mutation in thrombophilic pedigrees of French origin
    P Couture
    Department of Internal Medicine, CHUL Research Center, CHUQ, Quebec, Canada
    Thromb Haemost 86:1000-6. 2001
    ....
  5. ncbi request reprint Type I protein C deficiency in French Canadians: evidence of a founder effect and association of specific protein C gene mutations with plasma protein C levels
    P Couture
    Laboratory of Molecular Endocrinology, CHUL Research Center, Quebec, Canada
    Thromb Haemost 80:551-6. 1998
    ..4% of the variation of immunologic PROC levels in non-deficient subjects. These results suggest that the nature of the mutation in the coding sequence of PROC gene may modulate immunologic plasma PROC levels...
  6. ncbi request reprint The impact of UGT1A8, UGT1A9, and UGT2B7 genetic polymorphisms on the pharmacokinetic profile of mycophenolic acid after a single oral dose in healthy volunteers
    E Levesque
    Research Center, CHUL Research Center and Faculty of Pharmacy, Laval University, Quebec, Canada
    Clin Pharmacol Ther 81:392-400. 2007
    ....