C Weijer

Summary

Affiliation: Dalhousie University
Country: Canada

Publications

  1. ncbi request reprint When are research risks reasonable in relation to anticipated benefits?
    Charles Weijer
    Department of Bioethics, Dalhousie University, 5849 University Avenue, Halifax, Nova Scotia B3H 4H7, Canada
    Nat Med 10:570-3. 2004
  2. ncbi request reprint The ethics of placebo-controlled trials
    Charles Weijer
    Department of Bioethics, Dalhousie University, Halifax, Nova Scotia, Canada
    J Bone Miner Res 18:1150-3. 2003
  3. ncbi request reprint Continuing review of clinical research Canadian-style
    Charles Weijer
    Department of Bioethics, Dalhousie University, Halifax, NS
    Clin Invest Med 25:92-3. 2002
  4. pmc A death in the family: reflections on the Terri Schiavo case
    Charles Weijer
    McMaster University, Hamilton, Ont
    CMAJ 172:1197-8. 2005
  5. pmc Refuting the net risks test: a response to Wendler and Miller's "Assessing research risks systematically"
    C Weijer
    Department of Philosophy, Talbot College, University of Western Ontario, London, Ontario, Canada, N6A 3K7
    J Med Ethics 33:487-90. 2007
  6. ncbi request reprint Protecting communities in pharmacogenetic and pharmacogenomic research
    C Weijer
    Department of Bioethics, Dalhousie University, Halifax, Nova Scotia, Canada
    Pharmacogenomics J 4:9-16. 2004
  7. pmc The ethical analysis of risk in intensive care unit research
    Charles Weijer
    Dalhousie University, Halifax, Canada
    Crit Care 8:85-6. 2004
  8. ncbi request reprint The quest for legitimacy: comment on Cox Macpherson's 'To strengthen consensus, consult the stakeholders'
    Charles Weijer
    Deparment of Bioethics, Dalhousie University, 5849 University Avenue, Halifax, Nova Scotia, Canada, B3H 4H7
    Bioethics 18:293-300. 2004
  9. ncbi request reprint Ethics. Protecting communities in biomedical research
    C Weijer
    Department of Bioethics, Dalhousie University, Halifax, Nova Scotia, B3H 4H7, Canada
    Science 289:1142-4. 2000
  10. ncbi request reprint Protecting communities in research: current guidelines and limits of extrapolation
    C Weijer
    Department of Bioethics, Dalhousie University, Halifax, Nova Scotia, Canada
    Nat Genet 23:275-80. 1999

Collaborators

Detail Information

Publications48

  1. ncbi request reprint When are research risks reasonable in relation to anticipated benefits?
    Charles Weijer
    Department of Bioethics, Dalhousie University, 5849 University Avenue, Halifax, Nova Scotia B3H 4H7, Canada
    Nat Med 10:570-3. 2004
  2. ncbi request reprint The ethics of placebo-controlled trials
    Charles Weijer
    Department of Bioethics, Dalhousie University, Halifax, Nova Scotia, Canada
    J Bone Miner Res 18:1150-3. 2003
  3. ncbi request reprint Continuing review of clinical research Canadian-style
    Charles Weijer
    Department of Bioethics, Dalhousie University, Halifax, NS
    Clin Invest Med 25:92-3. 2002
  4. pmc A death in the family: reflections on the Terri Schiavo case
    Charles Weijer
    McMaster University, Hamilton, Ont
    CMAJ 172:1197-8. 2005
  5. pmc Refuting the net risks test: a response to Wendler and Miller's "Assessing research risks systematically"
    C Weijer
    Department of Philosophy, Talbot College, University of Western Ontario, London, Ontario, Canada, N6A 3K7
    J Med Ethics 33:487-90. 2007
    ..This response argues that the net risks test meets none of these criteria and concludes that it is not a viable alternative to component analysis...
  6. ncbi request reprint Protecting communities in pharmacogenetic and pharmacogenomic research
    C Weijer
    Department of Bioethics, Dalhousie University, Halifax, Nova Scotia, Canada
    Pharmacogenomics J 4:9-16. 2004
    ..Rather, application of these policy protections must take into account particulars of both planned research and the communities involved...
  7. pmc The ethical analysis of risk in intensive care unit research
    Charles Weijer
    Dalhousie University, Halifax, Canada
    Crit Care 8:85-6. 2004
    ..This realization has important implications for review by institutional review boards of such research and for the informed consent process...
  8. ncbi request reprint The quest for legitimacy: comment on Cox Macpherson's 'To strengthen consensus, consult the stakeholders'
    Charles Weijer
    Deparment of Bioethics, Dalhousie University, 5849 University Avenue, Halifax, Nova Scotia, Canada, B3H 4H7
    Bioethics 18:293-300. 2004
  9. ncbi request reprint Ethics. Protecting communities in biomedical research
    C Weijer
    Department of Bioethics, Dalhousie University, Halifax, Nova Scotia, B3H 4H7, Canada
    Science 289:1142-4. 2000
    ..Depending on the particular community, consent and consultation, consultation alone, or no added protections may be required for research...
  10. ncbi request reprint Protecting communities in research: current guidelines and limits of extrapolation
    C Weijer
    Department of Bioethics, Dalhousie University, Halifax, Nova Scotia, Canada
    Nat Genet 23:275-80. 1999
    ....
  11. ncbi request reprint Placebo-controlled trials in schizophrenia: are they ethical? Are they necessary?
    C Weijer
    Dalhousie University, Halifax, Canada
    Schizophr Res 35:211-8; discussion 227-36. 1999
    ..While the use of a placebo control may be acceptable in carefully defined circumstances, in most cases the use of an active control in schizophrenia research is ethically and scientifically preferable...
  12. pmc Bioethics for clinicians: 16. Dealing with demands for inappropriate treatment
    C Weijer
    Mount Sinai Hospital, Toronto, Ont
    CMAJ 159:817-21. 1998
    ..Institutions should ensure that fair and unambiguous procedures for dealing with such cases are laid out in policy statements...
  13. pmc Bioethics for clinicians: 10. Research ethics
    C Weijer
    Mount Sinai Hospital, Toronto, Ont
    CMAJ 156:1153-7. 1997
    ..When difficulties arise, they should consult the existing literature and seek the advice of experts in research ethics...
  14. pmc Trust based obligations of the state and physician-researchers to patient-subjects
    P B Miller
    Department of Philosophy, University of Toronto, Ontario, Canada
    J Med Ethics 32:542-7. 2006
    ....
  15. ncbi request reprint Hospital policy on appropriate use of life-sustaining treatment. University of Toronto Joint Centre for Bioethics/Critical Care Medicine Program Task Force
    P A Singer
    University of Toronto Joint Centre for Bioethics, Ontario, Canada
    Crit Care Med 29:187-91. 2001
    ..CONCLUSIONS: This article describes the key issues faced by the Task Force while developing its policy. It will provide a useful starting point for other groups developing policy on appropriate use of life-sustaining treatment...
  16. doi request reprint A comparison of journal instructions regarding institutional review board approval and conflict-of-interest disclosure between 1995 and 2005
    A Rowan-Legg
    Dr Anne Rowan Legg, Department of Pediatrics, IWK Health Centre, 5850 University Avenue, PO Box 9700, Halifax, Canada B3K6R8
    J Med Ethics 35:74-8. 2009
    ..To compare 2005 and 1995 ethics guidelines from journal editors to authors regarding requirements for institutional review board (IRB) approval and conflict-of-interest (COI) disclosure...
  17. ncbi request reprint I need a placebo like I need a hole in the head
    Charles Weijer
    Department of Bioethics, Dalhousie University, Halifax, Canada
    J Law Med Ethics 30:69-72. 2002
  18. ncbi request reprint Informing study participants of research results: an ethical imperative
    Conrad V Fernandez
    Division of Pediatric Hematology Oncology, Department of Pediatrics, IWK Health Centre and Dalhousie University, Halifax, Nova Scotia, Canada
    IRB 25:12-9. 2003
  19. ncbi request reprint Ethics of surgical training in developing countries
    Kevin M Ramsey
    Cumberland Regional Health Care Centre, Amherst, Canada
    World J Surg 31:2067-9; discussion 2070-1. 2007
    ..All training programs need to develop a structured ethical review for international electives to protect their trainees and their patients from harm...
  20. ncbi request reprint Lessons from everyday lives: a moral justification for acute care research
    Andrew D McRae
    Department of Bioethics, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    Crit Care Med 30:1146-51. 2002
    ..Our justification for emergency research also suggests additional protections for emergency research participants, including a stringent threshold for research risk, that still permit important research to proceed...
  21. ncbi request reprint Meaningful work as due inducement
    Charles Weijer
    Department of Philosophy, Talbot College, University of Western Ontario, London ON N6A 3K7, Canada
    Theor Med Bioeth 26:431-5. 2005
  22. pmc Placebo trials and tribulations
    Charles Weijer
    Department of Bioethics, Dalhousie University, Halifax charles weijerAdal ca
    CMAJ 166:603-4. 2002
  23. ncbi request reprint The return of research results to participants: pilot questionnaire of adolescents and parents of children with cancer
    C V Fernandez
    Department of Pediatrics, IWK Health Centre, Halifax, Nova Scotia, Canada
    Pediatr Blood Cancer 48:441-6. 2007
    ..We examined the needs and attitudes of parents of children with cancer and of adolescents with cancer to the return of research results...
  24. pmc Providing research results to participants: attitudes and needs of adolescents and parents of children with cancer
    Conrad Vincent Fernandez
    Department of Pediatrics, IWK Health Centre, Dalhousie University, 5850 University Ave, PO Box 9700, Halifax, Nova Scotia, B3K 6R8, Canada
    J Clin Oncol 27:878-83. 2009
    ..There is an increasing demand for researchers to provide research results to participants. Our aim was to define an appropriate process for this, based on needs and attitudes of participants...
  25. ncbi request reprint Obligations in offering to disclose genetic research results
    Conrad V Fernandez
    Dalhousie University, Canada
    Am J Bioeth 6:44-6; author reply W10-2. 2006
  26. ncbi request reprint Evaluating benefits and harms in intensive care research
    Charles Weijer
    Department of Philosophy, University of Western Ontario, 1151 Richmond Street, N6A 3K7, London, Ontario, Canada
    Intensive Care Med 33:1819-22. 2007
  27. ncbi request reprint A critical appraisal of protections for aboriginal communities in biomedical research
    Charles Weijer
    Department of Bioethics, Dalhousie University, Halifax, Canada
    Jurimetrics 42:187-98. 2002
    ..To explore how such a principle might be specified and operationalized, it reviews existing guidelines for protecting aboriginal communities and points out problems with these guidelines and areas for further work...
  28. ncbi request reprint Therapeutic obligation in clinical research
    Charles Weijer
    Department of Bioethics, Dalhousie University
    Hastings Cent Rep 33:3. 2003
  29. ncbi request reprint The research subject as wage earner
    James A Anderson
    Department of Bioethics, Dalhousie University, Halifax, Canada
    Theor Med Bioeth 23:359-76. 2002
    ..If we accept that paid research subjects are wage earners like any other, then the implications for changes to current practice are substantial...
  30. ncbi request reprint Fiduciary obligation in clinical research
    Paul B Miller
    Department of Philosophy at the University of Toronto in Toronto, Ontario, Canada
    J Law Med Ethics 34:424-40. 2006
  31. ncbi request reprint Equipoise and the duty of care in clinical research: a philosophical response to our critics
    Paul B Miller
    University of Toronto, Toronto, Ontario, Canada
    J Med Philos 32:117-33. 2007
    ..However, recognizing that constructive contributions to the field ought to enjoy priority, we presently scrutinize the constructive dimension of their work. We argue that it is wanting in several respects...
  32. ncbi request reprint Offering to return results to research participants: attitudes and needs of principal investigators in the Children's Oncology Group
    Conrad V Fernandez
    Department of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia, Canada
    J Pediatr Hematol Oncol 25:704-8. 2003
    ..The authors determined current practice and attitudes and needs of researchers in establishing programs to return results to research participants...
  33. ncbi request reprint Disclosure of the right of research participants to receive research results: an analysis of consent forms in the Children's Oncology Group
    Conrad V Fernandez
    Department of Pediatrics, IWK Health Centre, Dalhousie University, Halifax, Nova Scotia, Canada
    Cancer 97:2904-9. 2003
    ..The current study examined the offer of return of research results by analyzing consent forms from 2 acute lymphoblastic leukemia studies of the 235 institutional members of the Children's Oncology Group...
  34. ncbi request reprint Risk in emergency research using a waiver of/exception from consent: implications of a structured approach for institutional review board review
    Andrew D McRae
    Department of Emergency Medicine, Queen s University, Kingston, Ontario, Canada
    Acad Emerg Med 12:1104-12. 2005
    ..The hypothesis was that component analysis could be used with a high degree of interrater reliability, and that the vast majority of emergency research would comply with a minimal-risk threshold...
  35. doi request reprint U.S. Federal Regulations for emergency research: a practical guide and commentary
    Andrew McRae
    Department of Emergency Medicine, Queen s University, Kingston, Ontario, Canada
    Acad Emerg Med 15:88-97. 2008
    ..It explores the challenges for IRB review listed above, and offers potential solutions to these problems...
  36. ncbi request reprint The balm of Gilead: is the provision of treatment to those who seroconvert in HIV prevention trials a matter of moral obligation or moral negotiation?
    Charles Weijer
    Department of Philosophy, Talbot College, The University of Western Ontario, Canada
    J Law Med Ethics 34:793-808. 2006
    ..We outline an alternative approach to the problem based on moral negotiation...
  37. ncbi request reprint The forum. The importance of context in international research
    Fern Brunger
    Ethics Behav 12:371-2, 384-7. 2002
  38. ncbi request reprint The ethics of placebo-controlled trials
    Charles Weijer
    N Engl J Med 346:382-3. 2002
  39. ncbi request reprint Is clinical research and ethics a zero-sum game?
    Charles Weijer
    Crit Care Med 33:912-3. 2005
  40. ncbi request reprint When argument fails
    Charles Weijer
    Dalhousie University
    Am J Bioeth 2:10-1. 2002
  41. ncbi request reprint Rehabilitating equipoise
    Paul B Miller
    University of Toronto, Canada
    Kennedy Inst Ethics J 13:93-118. 2003
    ..CE sets out a standard for the social approval of research by institutional review boards. Viewed this way, FE and CE are not necessarily competing notions, but rather address complementary moral concerns...
  42. ncbi request reprint Will the real Charles Fried please stand up?
    Paul B Miller
    University of Toronto, Canada
    Kennedy Inst Ethics J 13:353-7. 2003
    ....
  43. ncbi request reprint Waiver of consent for emergency research
    Andrew D McRae
    Ann Emerg Med 44:278-9; author reply 279-80. 2004
  44. ncbi request reprint Ethical issues associated with the introduction of new surgical devices, or just because we can, doesn't mean we should
    Sue Ross
    Department of Obstetrics and Gynaecology, University of Calgary, Calgary AB
    J Obstet Gynaecol Can 30:508-13. 2008
    ....
  45. ncbi request reprint Is the use of placebo controls ethically permissible in clinical trials of agents intended to reduce fractures in osteoporosis?
    Baruch A Brody
    Center for Medical Ethics and Health Policy, Baylor College of Medicine, Houston, Texas, USA
    J Bone Miner Res 18:1105-9. 2003
    ..Active control trials are permissible and desirable if they can be designed and conducted in ways that overcome the interpretive difficulties often associated with such trials...
  46. ncbi request reprint Importance of informed consent in offering to return research results to research participants
    Conrad V Fernandez
    Med Pediatr Oncol 41:592-3. 2003
  47. ncbi request reprint A critical history of individual and collective ethics in the lineage of Lellouch and Schwartz
    Charles M Heilig
    Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30341 371 7, USA
    Clin Trials 2:244-53. 2005
    ..Finally, the paper concludes with the observation that a systematic, comprehensive ethical framework must be identified to fulfill the intuitions behind individual and collective ethics...
  48. pmc Considerations and costs of disclosing study findings to research participants
    Conrad V Fernandez
    Division of Pediatric Hematology and Oncology, Department of Pediatrics, IWK Health Centre Halifax, Nova Scotia
    CMAJ 170:1417-9. 2004