Jian Wang

Summary

Affiliation: Dalhousie University
Country: Canada

Publications

  1. pmc Role of mitochondrial dysfunction in cellular responses to S-(1,2-dichlorovinyl)-L-cysteine in primary cultures of human proximal tubular cells
    Feng Xu
    Department of Pharmacology, Wayne State University School of Medicine, 540 East Canfield Avenue, Detroit, MI 48201, USA
    Biochem Pharmacol 76:552-67. 2008
  2. ncbi request reprint Carboplatin-induced early cochlear lesion in chinchillas
    Jian Wang
    School of Human Communication Disorders, Dalhousie University, 5599 Fenwick Street, B3H 1R2 Halifax, NS, Canada
    Hear Res 181:65-72. 2003
  3. doi request reprint Over-expression of X-linked inhibitor of apoptosis protein slows presbycusis in C57BL/6J mice
    Jian Wang
    The Affiliated Sixth People s Hospital, Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, China
    Neurobiol Aging 31:1238-49. 2010
  4. ncbi request reprint The effect of gap-marker spectrum on gap-evoked auditory response from the inferior colliculus and auditory cortex of guinea pigs
    Jian Wang
    School of Human Communication Disorders, Dalhousie University, Halifax, NS, Canada
    Int J Audiol 45:521-7. 2006
  5. ncbi request reprint Is duration tuning a transient process in the inferior colliculus of guinea pigs?
    Jian Wang
    School of Human Communication Disorders, Dalhousie University, 5599 Fenwick Street, Halifax, Canada NS B3H 1R2
    Brain Res 1114:63-74. 2006
  6. ncbi request reprint Important factors for the hearing loss caused by the triple semicircular canal occlusion in guinea pigs
    Shankai Yin
    Department of Otolaryngology, Affiliated Sixth People s Hospital, Shanghai Jiao Tong University, Shanghai, China
    Otol Neurotol 28:513-9. 2007
  7. ncbi request reprint [The experimental study of the anti-damage effect of iminoethyl-lysine on noise-induced cochlea damage in guinea pig]
    Min Xiong
    Department of Otolaryngology, General Hospital of PLA Guangzhou Command, Guangzhou 510010, China
    Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 20:356-8. 2002
  8. doi request reprint The effect of noise-induced sloping high-frequency hearing loss on the gap-response in the inferior colliculus and auditory cortex of guinea pigs
    Shan Kai Yin
    The Affiliated Sixth People s Hospital, Otorhinolaryngology Institute, Shanghai Jiao Tong University, Shanghai 200233, China
    Hear Res 239:126-40. 2008
  9. ncbi request reprint General anesthesia changes gap-evoked auditory responses in guinea pigs
    Yanmei Feng
    Department of Otolaryngology, No 6 People s Hospital, Shanghai JiaoTong University Shanghai, China
    Acta Otolaryngol 127:143-8. 2007
  10. ncbi request reprint Gamma-aminobutyric acid circuits shape response properties of auditory cortex neurons
    Jian Wang
    Center for Hearing and Deafness, State University of New York at Buffalo, Buffalo, NY 14214, USA
    Brain Res 944:219-31. 2002

Collaborators

  • Bin Wang
  • Manohar Bance
  • George S Robertson
  • R J Salvi
  • U E Lang
  • A D Krahn
  • Kevin Dawson
  • K Lukowiak
  • James Simpkins
  • Hans Peter Lipp
  • Rona Giffard
  • Gail M Seigel
  • Yong Li
  • C M Morshead
  • Wei Wang
  • Minh Dang Nguyen
  • Shankai Yin
  • Changping Zou
  • Molly Brewer
  • Yanmei Feng
  • Dongzhen Yu
  • Eftekhar Eftekharpour
  • Soheila Karimi-Abdolrezaee
  • Feng Xu
  • Xiaoping Yu
  • Amrita V Kamath
  • Su Yeon Shim
  • Shan Kai Yin
  • Zhengnong Chen
  • Frits Thorsen
  • Catherine L Weber
  • Ya Ru Su
  • Chen Wang
  • Michael G Fehlings
  • Rongshi Li
  • David Gershenson
  • J Taylor Wharton
  • Robert Bast
  • Nelly Auersperg
  • Rama Soundararajan
  • Robert A Hegele
  • Duraisamy Senthil
  • Nathalie Strutz-Seebohm
  • David Pearce
  • Yanzhi Wang
  • Russell R Broaddus
  • Wan dong She
  • Monica Liebert
  • H Barton Grossman
  • Changchun Zou
  • ShuHong Liu
  • Xiang Dong Yang
  • Ying Yong Hou
  • Xiaoyan Zheng
  • Bruce D Walker
  • Min Xiong
  • David A Putt
  • Lawrence H Lash
  • Yuanqiong Luo
  • Yong Tang
  • Kei Ichiro Ishiguro
  • Naoyuki Asada
  • Na Wei
  • Jundong Zhu
  • Hui Chang
  • Yoshihiro Nakatani
  • Francis Y Lee
  • Kamon Sanada
  • Yong Zhou
  • Gernot Neumayer
  • Qianyong Zhang
  • Mantian Mi
  • Zheng Nong Chen
  • Hong Chi Tran
  • Punit H Marathe
  • Irene Papanayotou
  • Yan Mei Feng
  • Paal Henning Pedersen
  • Rui Hong Sheng
  • Wen Yuan Zhu
  • Jiri Frohlich
  • Yu ping Jiang
  • Jian Jun Wu
  • Yan Jun Lei
  • Li Ping You
  • Xin Ye Xu
  • Yan Chen
  • Zi Ang Pan
  • Clifford Chan-Yan
  • Hong xia Peng

Detail Information

Publications54

  1. pmc Role of mitochondrial dysfunction in cellular responses to S-(1,2-dichlorovinyl)-L-cysteine in primary cultures of human proximal tubular cells
    Feng Xu
    Department of Pharmacology, Wayne State University School of Medicine, 540 East Canfield Avenue, Detroit, MI 48201, USA
    Biochem Pharmacol 76:552-67. 2008
    ..These results support the conclusion that mitochondrial dysfunction is an early and obligatory step in DCVC-induced cytotoxicity in hPT cells...
  2. ncbi request reprint Carboplatin-induced early cochlear lesion in chinchillas
    Jian Wang
    School of Human Communication Disorders, Dalhousie University, 5599 Fenwick Street, B3H 1R2 Halifax, NS, Canada
    Hear Res 181:65-72. 2003
    ..The large fluctuations in SDR and DDR that occur several hours after carboplatin treatment are most likely due to the neurotoxic effects of carboplatin...
  3. doi request reprint Over-expression of X-linked inhibitor of apoptosis protein slows presbycusis in C57BL/6J mice
    Jian Wang
    The Affiliated Sixth People s Hospital, Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, China
    Neurobiol Aging 31:1238-49. 2010
    ..These results suggest that XIAP over-expression reduces age-related hearing loss and hair cell death in the cochlea...
  4. ncbi request reprint The effect of gap-marker spectrum on gap-evoked auditory response from the inferior colliculus and auditory cortex of guinea pigs
    Jian Wang
    School of Human Communication Disorders, Dalhousie University, Halifax, NS, Canada
    Int J Audiol 45:521-7. 2006
    ..These results suggest that the total bandwidth of all auditory channels that are recruited determine the temporal resolution measured in gap-evoked potentials...
  5. ncbi request reprint Is duration tuning a transient process in the inferior colliculus of guinea pigs?
    Jian Wang
    School of Human Communication Disorders, Dalhousie University, 5599 Fenwick Street, Halifax, Canada NS B3H 1R2
    Brain Res 1114:63-74. 2006
    ..Therefore, duration tuning appears to be a transient neural coding process in the IC of guinea pigs. Duration tuning for these types of neurons may have been blurred by the use of a relatively unselective, long window...
  6. ncbi request reprint Important factors for the hearing loss caused by the triple semicircular canal occlusion in guinea pigs
    Shankai Yin
    Department of Otolaryngology, Affiliated Sixth People s Hospital, Shanghai Jiao Tong University, Shanghai, China
    Otol Neurotol 28:513-9. 2007
    ..The damage to the membranous semicircular labyrinth is the single major contributor to hearing loss caused by TSCO...
  7. ncbi request reprint [The experimental study of the anti-damage effect of iminoethyl-lysine on noise-induced cochlea damage in guinea pig]
    Min Xiong
    Department of Otolaryngology, General Hospital of PLA Guangzhou Command, Guangzhou 510010, China
    Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 20:356-8. 2002
    ..To investigate the anti-damage effect of iminoethyl-lysine on noise-induced cochlea damage in guinea pig...
  8. doi request reprint The effect of noise-induced sloping high-frequency hearing loss on the gap-response in the inferior colliculus and auditory cortex of guinea pigs
    Shan Kai Yin
    The Affiliated Sixth People s Hospital, Otorhinolaryngology Institute, Shanghai Jiao Tong University, Shanghai 200233, China
    Hear Res 239:126-40. 2008
    ..These results strongly indicate that a high-frequency hearing loss exerted an off-channel impact on temporal processing in the low-frequency region of the auditory system...
  9. ncbi request reprint General anesthesia changes gap-evoked auditory responses in guinea pigs
    Yanmei Feng
    Department of Otolaryngology, No 6 People s Hospital, Shanghai JiaoTong University Shanghai, China
    Acta Otolaryngol 127:143-8. 2007
    ..General anesthesia induced by sodium pentobarbital reduces temporal resolution as represented by an increase in the threshold of gap-evoked auditory responses in guinea pigs...
  10. ncbi request reprint Gamma-aminobutyric acid circuits shape response properties of auditory cortex neurons
    Jian Wang
    Center for Hearing and Deafness, State University of New York at Buffalo, Buffalo, NY 14214, USA
    Brain Res 944:219-31. 2002
    ..The inhibitory circuits that generate nonmonotonic rate-level functions are separate from those that influence other response properties of AI neurons...
  11. ncbi request reprint Functional reorganization in chinchilla inferior colliculus associated with chronic and acute cochlear damage
    Jian Wang
    Hearing Research Lab, 215 Parker Hall, University of Buffalo, Buffalo, NY 14210, USA
    Hear Res 168:238-49. 2002
    ..The results suggest that lesioned-induced central auditory plasticity could contribute to several symptoms associated with sensorineural hearing loss such as loudness recruitment, tinnitus and poor speech discrimination in noise...
  12. ncbi request reprint Coordination of presynaptic and postsynaptic maturation in a zebra finch forebrain motor control nucleus during song learning
    Jian Wang
    Laboratory for Vocal Behaviour Mechanisms, Brain Science Institute, RIKEN, 2 1 Hirosawa, Wako Shi, Saitama 351 0198, Japan
    Eur J Neurosci 24:2859-69. 2006
    ..These results suggest that regulation of learning capacity may occur in part by coordination of presynaptic and postsynaptic function...
  13. ncbi request reprint Human glioblastoma biopsy spheroids xenografted into the nude rat brain show growth inhibition after stereotactic radiosurgery
    Frits Thorsen
    Department of Oncology and Medical Physics, Haukeland University Hospital, Jonas Lies vei 65, 5021, Bergen, Norway
    J Neurooncol 82:1-10. 2007
    ..In this work, the growth and invasiveness of human glioblastoma spheroids xenografted into nude rat brains were assessed after radiosurgery. Temporary in vitro as well as long-term in vivo radiation effects were studied...
  14. ncbi request reprint Triple semicircular canal occlusion in guinea pigs with endolymphatic hydrops
    Shankai Yin
    Department of Otolaryngology, Affiliated Sixth People s Hospital, Shanghai Jiao Tong University, Shanghai, China
    Otol Neurotol 27:78-85. 2006
    ..This surgery is safe in ears with endolymphatic hydrops...
  15. ncbi request reprint Design and synthesis of 5-aryl-pyridone-carboxamides as inhibitors of anaplastic lymphoma kinase
    Rongshi Li
    ChemBridge Research Laboratories and ChemBridge Corporation, 16981 Via Tazon, Suites K and G, San Diego, CA 92127, USA
    J Med Chem 49:1006-15. 2006
    ..Herein the details of the design process and synthesis of these novel pyridones, along with their enzymatic and cell-based activity, are discussed...
  16. ncbi request reprint Delayed transplantation of adult neural precursor cells promotes remyelination and functional neurological recovery after spinal cord injury
    Soheila Karimi-Abdolrezaee
    Division of Cell and Molecular Biology, Toronto Western Research Institute, Krembil Neuroscience Center, Toronto, Ontario, M5T 2S8, Canada
    J Neurosci 26:3377-89. 2006
    ..Our data provide strong evidence in support of the feasibility of adult NPCs for cell-based remyelination after SCI...
  17. ncbi request reprint Heme oxygenase 2 is neuroprotective against intracerebral hemorrhage
    Jian Wang
    Department of Anesthesiology Critical Care Medicine, Johns Hopkins University School of Medicine, 720 Rutland Avenue, Ross Bldg 364 365, Baltimore, MD 21205, USA
    Neurobiol Dis 22:473-6. 2006
    ....
  18. ncbi request reprint Steroid hormone-dependent transformation of polyhomeotic mutant neurons in the Drosophila brain
    Jian Wang
    Department of Entomology, University of Maryland, College Park, 20742, USA
    Development 133:1231-40. 2006
    ..Taken together, Drosophila Ph is essential for governing neuronal diversity, especially during steroid hormone signaling...
  19. ncbi request reprint 4-HPR modulates gene expression in ovarian cells
    Molly Brewer
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Arizona Cancer Center, Tucson, 85724, USA
    Int J Cancer 119:1005-13. 2006
    ..These findings suggest that 4-HPR acts through different mechanisms in premalignant ovarian surface cells and cancer cells, with a preventive effect in premalignant cells and a treatment effect in cancer cells...
  20. ncbi request reprint Myelination of congenitally dysmyelinated spinal cord axons by adult neural precursor cells results in formation of nodes of Ranvier and improved axonal conduction
    Eftekhar Eftekharpour
    Division of Cell and Molecular Biology, Toronto Western Research Institute, Krembil Neuroscience Center, Toronto, Ontario, Canada M5T 2S8
    J Neurosci 27:3416-28. 2007
    ..These data suggest the therapeutic potential of aNPCs to promote functionally significant myelination in CNS disorders characterized by longstanding myelin deficiency...
  21. ncbi request reprint BRCA1 overexpression sensitizes cancer cells to lovastatin via regulation of cyclin D1-CDK4-p21WAF1/CIP1 pathway: analyses using a breast cancer cell line and tumoral xenograft model
    Xiaoping Yu
    Department of Public Health, School of Preclinical Medicine, Chengdu Medical College, Chengdu, Sichuan 610081, P R China
    Int J Oncol 33:555-63. 2008
    ....
  22. doi request reprint Protein 600 is a microtubule/endoplasmic reticulum-associated protein in CNS neurons
    Su Yeon Shim
    Hotchkiss Brain Institute, Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada T2N 4N1
    J Neurosci 28:3604-14. 2008
    ..Thus, p600 constitutes the only known MAP to associate with the ER in neurons, and this interaction may impact on multiple cellular processes ranging from neuronal development to neuronal maturation and plasticity...
  23. doi request reprint Local inhibition shapes duration tuning in the inferior colliculus of guinea pigs
    Shankai Yin
    The Affiliated Sixth People s Hospital, Otolaryngology Institute of Shanghai Jiao Tong University, 600 Yishan Road, 7th Building Rm220, Shanghai 200233, China
    Hear Res 237:32-48. 2008
    ..In conclusion, the inhibitory effect on the early responses appears to be the main contributor for the duration selectivity of the IC in guinea pigs; potential mechanisms for this duration selectivity are also discussed...
  24. ncbi request reprint Generation of functional inhibitory neurons in the adult rat hippocampus
    ShuHong Liu
    Neuroscience Research Group, Department of Physiology and Biophysics, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada, T2N 4N1
    J Neurosci 23:732-6. 2003
    ..These data show for the first time that functional inhibitory neurons are recruited in the dentate gyrus of adult rats...
  25. ncbi request reprint Multiple huge cutaneous horns overlying verrucae vulgaris induced by human papillomavirus type 2: a case report
    Chen Wang
    Br J Dermatol 156:760-2. 2007
  26. ncbi request reprint Stability of lipids on peritoneal dialysis in a patient with familial LCAT deficiency
    Catherine L Weber
    Department of Medicine, Section of Nephrology, Laboratory Medicine, University of British Columbia St Paul s Hospital, 1081 Burrard Street, Providence Building, Room 6010A, Vancouver, British Columbia, Canada V6Z 1Y6
    Nephrol Dial Transplant 22:2084-8. 2007
  27. ncbi request reprint Preclinical pharmacokinetics and in vitro metabolism of dasatinib (BMS-354825): a potent oral multi-targeted kinase inhibitor against SRC and BCR-ABL
    Amrita V Kamath
    Department of Pharmacokinetic and Pharmacodynamic Sciences, Genentech, 1 DNA Way, South San Francisco, CA 94080, USA
    Cancer Chemother Pharmacol 61:365-76. 2008
    ..Possible mechanisms contributing to the incomplete oral bioavailability of dasatinib in animals were investigated...
  28. ncbi request reprint Overexpression of lentivirus-mediated glial cell line-derived neurotrophic factor in bone marrow stromal cells and its neuroprotection for the PC12 cells damaged by lactacystin
    Ya Ru Su
    Department of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China
    Neurosci Bull 23:67-74. 2007
    ....
  29. ncbi request reprint In vitro targeting of NG2 antigen by 213Bi-9.2.27 alpha-immunoconjugate induces cytotoxicity in human uveal melanoma cells
    Yong Li
    Centre for Experimental Radiation Oncology, Cancer Care Centre, St George Hospital, Kogarah, NSW, Australia
    Invest Ophthalmol Vis Sci 46:4365-71. 2005
    ..2.27 and subsequently to assess the in vitro specificity and cytotoxicity of mAb 9.2.27 conjugated to the alpha-particle-emitting radioisotope 213bismuth (213Bi-9.2.27) for uveal melanoma cells...
  30. ncbi request reprint Reduced locomotion in the serum and glucocorticoid inducible kinase 3 knock out mouse
    Undine E Lang
    Department of Physiology I, Gmelinstr 5, 72076 Tuebingen, Germany
    Behav Brain Res 167:75-86. 2006
    ..In conclusion, lack of SGK3 leads to subtle behavioral defects which may result from deranged neuronal regulation of transporters and ion channels...
  31. ncbi request reprint Characterization and body distribution of beta-elemene solid lipid nanoparticles (SLN)
    Yanzhi Wang
    School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, China
    Drug Dev Ind Pharm 31:769-78. 2005
    ..Therefore, the SLN containing beta-elemene might be an attractive candidate for the treatment of liver cancer...
  32. ncbi request reprint The chemopreventive agents 4-HPR and DFMO inhibit growth and induce apoptosis in uterine leiomyomas
    Russell R Broaddus
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston, Tex, USA
    Am J Obstet Gynecol 190:686-92. 2004
    ..This study examined the effects of the chemopreventive agents 4-(N-hydroxyphenyl)retinamide (4-HPR) and alpha-difluoromethylornithine (DFMO) on leiomyoma growth...
  33. ncbi request reprint [Screening of the drug resistance-associated gene in HepG2 cell line transfected with aldose reductase like gene-1 (ARL-1)]
    Xiang Dong Yang
    Centre of Molecular Biology, Nanhua University, Hengyang, Hunan, PR China
    Ai Zheng 22:1289-95. 2003
    ....
  34. ncbi request reprint Cdk5 activation induces hippocampal CA1 cell death by directly phosphorylating NMDA receptors
    Jian Wang
    Department of Physiology and Biophysics, University of Calgary, Calgary T2N 4N1, Canada
    Nat Neurosci 6:1039-47. 2003
    ..Thus, we conclude that modulation of NMDA receptors by Cdk5 is the primary intracellular event underlying the ischemic injury of CA1 pyramidal neurons...
  35. ncbi request reprint [Study on the origin and differentiation of gastrointestinal stromal tumors]
    Ying Yong Hou
    Department of Pathology, Cancer Hospital, Medical College of Fudan University, Shanghai 200032, China
    Zhonghua Bing Li Xue Za Zhi 32:106-10. 2003
    ..To explore the origin and differentiation of gastrointestinal stromal tumors (GISTs)...
  36. ncbi request reprint [Nerve tissue morphological study of tutin microinjection into pontine NPBM in two hours]
    Jian Wang
    Department of Physiology, West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China
    Hua Xi Yi Ke Da Xue Xue Bao 33:54-7. 2002
    ..To observe whether Tutin microinjection into the pontine NPBM respiratory area of rabbit will cause morphological damage to that area two hours later...
  37. ncbi request reprint TGF-beta signaling activates steroid hormone receptor expression during neuronal remodeling in the Drosophila brain
    Xiaoyan Zheng
    Department of Cell and Structural Biology, University of Illinois, Urbana, IL 61801, USA
    Cell 112:303-15. 2003
    ..We conclude that the Drosophila Activin signaling pathway mediates neuronal remodeling in part by regulating EcR-B1 expression...
  38. ncbi request reprint Interaction of calcineurin and type-A GABA receptor gamma 2 subunits produces long-term depression at CA1 inhibitory synapses
    Jian Wang
    Neuroscience Research Group, Department of Physiology and Biophysics, Faculty of Medicine, University of Calgary, Calgary, Canada, T2N 4N1
    J Neurosci 23:826-36. 2003
    ..Thus, an activity-dependent physical and functional interaction between CaN and GABA(A) receptors is both necessary and sufficient for inducing LTD at CA1 individual inhibitory synapses...
  39. ncbi request reprint Congenital and acquired long QT syndromes
    Bruce D Walker
    Division of Cardiology and the Blackburn Genetics Laboratory, Robarts Research Institute, University of Western Ontario, London
    Can J Cardiol 19:76-87. 2003
    ..This review summarizes the clinical, genetic and electrophysiological understanding of congenital and acquired LQTS...
  40. ncbi request reprint [Establishment and identification of the gene cell line transfected aldose reductase like gene and its drug resistance to drugs containing carbonyl group]
    Jian Wang
    Center of Molecular Biology of Nanhua University, Hengyang 421001, China
    Zhonghua Gan Zang Bing Za Zhi 10:445-8. 2002
    ..To investigate the relationship between aldose reductase like protein (ARL-1) gene overexpressed in HCC cells and drug-resistance of the cell to drugs containing carbonyl group...
  41. ncbi request reprint N-(4-hydroxyphenyl)retinamide (4-HPR) modulates GADD45 expression in radiosensitive bladder cancer cell lines
    Changping Zou
    Department of Obstetrics and Gynecology, The University of Texas Houston Medical School, Houston, TX 77030, USA
    Cancer Lett 180:131-7. 2002
    ..Once our results are verified and replicated by other investigators, 4-HPR may have a potential clinical implication in effectively treating bladder cancer in combination with low-gamma-irradiation therapy...
  42. ncbi request reprint [Peri-uvulopalatopharyng oplasty otoacoustic emissions in patients with obstructive sleep apnea-hypopnea syndrome]
    Wan dong She
    Department of Otorhinolaryngology, Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing 210008, China
    Zhonghua Er Bi Yan Hou Ke Za Zhi 39:48-51. 2004
    ..To study the cochlear function of patients with obstructive sleep apnea-hypopnea syndrome (OSAHS)...
  43. ncbi request reprint Cell-specific role for epsilon- and betaI-protein kinase C isozymes in protecting cortical neurons and astrocytes from ischemia-like injury
    Jian Wang
    Department of Anesthesia, School of Medicine, Stanford University, Stanford, CA 94305 5117, USA
    Neuropharmacology 47:136-45. 2004
    ..Our data demonstrate protection of neurons by selective activation of epsilonPKC but enhanced astrocyte cell death with selective inhibition of betaIPKC. Thus PKC isozymes exhibit cell type-specific effects on ischemia-like injury...
  44. ncbi request reprint A novel role for glucocorticoid-induced leucine zipper protein in epithelial sodium channel-mediated sodium transport
    Rama Soundararajan
    Division of Nephrology, Department of Medicine, University of California at San Francisco, San Francisco, California 94143 0532, USA
    J Biol Chem 280:39970-81. 2005
    ..These observations suggest a novel link between GILZ and regulation of epithelial sodium transport through modulation of ERK signaling and could represent an important pathway for mediating aldosterone actions in health and disease...
  45. ncbi request reprint In vitro model of normal, immortalized ovarian surface epithelial and ovarian cancer cells for chemoprevention of ovarian cancer
    Molly Brewer
    Department of Gynecologic Oncology, University of Texas, The M D Anderson Cancer Center, Houston, TX 77030, USA
    Gynecol Oncol 98:182-92. 2005
    ..However, the effectiveness of its application for different populations has been questioned because of the genetic differences among normal, high risk, and women with cancer...
  46. pmc Genotype-dependent expression of endothelial nitric oxide synthase (eNOS) and its regulatory proteins in cultured endothelial cells
    Duraisamy Senthil
    Division of Cardiothoracic Surgery, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA
    DNA Cell Biol 24:218-24. 2005
    ..However, the cigarette smoking-genotype interaction may require such in vivo conditions to be manifested...
  47. ncbi request reprint Neuroprotection by inhibition of matrix metalloproteinases in a mouse model of intracerebral haemorrhage
    Jian Wang
    Department of Pharmacological Sciences, University Medical Center at Stony Brook, Stony Brook, NY 11794 8651, USA
    Brain 128:1622-33. 2005
    ..Blockade of MMP activity during this critical period may have efficacy as a therapeutic strategy for the treatment of acute brain injury after ICH...
  48. pmc Regulation of GluR1 abundance in murine hippocampal neurones by serum- and glucocorticoid-inducible kinase 3
    Nathalie Strutz-Seebohm
    Department of Physiology I, University of Tuebingen, 72076 Tuebingen, Germany
    J Physiol 565:381-90. 2005
    ..The present observations disclose a novel mechanism in the regulation of GluR1...
  49. ncbi request reprint Mitochondria play a central role in estrogen-induced neuroprotection
    James W Simpkins
    Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX 76102, USA
    Curr Drug Targets CNS Neurol Disord 4:69-83. 2005
    ....
  50. ncbi request reprint Tuftsin fragment 1-3 is beneficial when delivered after the induction of intracerebral hemorrhage
    Jian Wang
    Department of Pharmacological Sciences, University Medical Center at Stony Brook, Stony Brook, NY 11794 8651, USA
    Stroke 36:613-8. 2005
    ..In this study, we investigate the protection and efficacy of treatment when MIF is administered 2 hours after collagenase injection...
  51. ncbi request reprint Effect of retinoic acid and interferon alpha-2a on transitional cell carcinoma of bladder
    Changping Zou
    Department of Obstetrics Gynecology and Urology, University of Arizona, Tucson, Arizona 85724, USA
    J Urol 173:247-51. 2005
    ....
  52. ncbi request reprint Transmembrane/juxtamembrane domain-dependent Dscam distribution and function during mushroom body neuronal morphogenesis
    Jian Wang
    Department of Cell and Structural Biology, University of Illinois, Urbana 61801, USA
    Neuron 43:663-72. 2004
    ..2] affects MB axons. These results suggest that exon 17.1 is minimally involved in axonal morphogenesis and that morphogenesis of MB axons probably involves multiple distinct exon 17.2-containing Dscam isoforms...
  53. ncbi request reprint Neuronal gene expression and function in the growth-stimulated R28 retinal precursor cell line
    Gail M Seigel
    Department of Ophthalmology, University at Buffalo, SUNY, NY 14214, USA
    Curr Eye Res 28:257-69. 2004
    ..In this study, we tested the hypothesis that the proliferative R28 retinal cell line contains subpopulations of cells that express neuronal mRNAs and proteins characteristic of CNS neurons...
  54. ncbi request reprint Beta blockers normalize QT hysteresis in long QT syndrome
    Andrew D Krahn
    Division of Cardiology, University of Western Ontario, London, Ontario, Canada
    Am Heart J 143:528-34. 2002
    ..This study was performed to evaluate the impact of beta blockers on QT adaptation to heart rate during the exercise and recovery phases of exercise testing in long QT syndrome...