Rudolf Uher

Summary

Affiliation: Dalhousie University
Country: Canada

Publications

  1. pmc Risk of mental illness in offspring of parents with schizophrenia, bipolar disorder, and major depressive disorder: a meta-analysis of family high-risk studies
    Daniel Rasic
    To whom correspondence should be addressed Department of Psychiatry, Canada Research Chair in Early Intervention in Psychiatry, Dalhousie University, 5909 Veterans Memorial Lane, Room 3089, Abbie J Lane Memorial Building, Halifax, Nova Scotia B3H 2E2, Canada fax 902 473 4877, E mail
    Schizophr Bull 40:28-38. 2014
  2. ncbi Gene-environment interactions in common mental disorders: an update and strategy for a genome-wide search
    Rudolf Uher
    Department of Psychiatry, Dalhousie University, 5909 Veterans Memorial Lane, Halifax, B3H 2E2, NS, Canada
    Soc Psychiatry Psychiatr Epidemiol 49:3-14. 2014
  3. pmc The impact of phenotypic and genetic heterogeneity on results of genome wide association studies of complex diseases
    Mirko Manchia
    Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
    PLoS ONE 8:e76295. 2013
  4. ncbi Why negative meta-analyses may be false?
    Tomas Hajek
    Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada Prague Psychiatric Center, Department of Psychiatry and Medical Psychology, 3 rd Faculty of Medicine, Charles University, Prague, Czech Republic Electronic address
    Eur Neuropsychopharmacol 23:1307-9. 2013
  5. ncbi Insulin resistance, diabetes mellitus, and brain structure in bipolar disorders
    Tomas Hajek
    1 Department of Psychiatry, Dalhousie University, Halifax, NS, Canada 2 Prague Psychiatric Center, Department of Psychiatry and Medical Psychology, 3rd School of Medicine, Charles University, Prague, Czech Republic
    Neuropsychopharmacology 39:2910-8. 2014
  6. ncbi Insulin resistance and outcome in bipolar disorder
    Cynthia V Calkin
    Cynthia V Calkin, MD, CCFP, FRCPC, Martina Ruzickova, MD, PhD, FRCPC, Department of Psychiatry, Dalhousie University, Halifax, Canada Rudolf Uher, MD, PhD, Department of Psychiatry, Dalhousie University, Halifax, Canada and Institute of Psychiatry, MRC Social, Genetic and Developmental Psychiatry Centre, King s College London, UK Tomas Hajek, MD, PhD, Department of Psychiatry, Dalhousie University, Halifax, Canada and Department of Psychiatry, 3rd School of Medicine, Prague, Charles University, Czech Republic Claire M Slaney, RN, Julie S Garnham, RNBN, Capital District Health Authority, Halifax, Canada M Claire O Donovan, MB, FRCPC, Department of Psychiatry, Dalhousie University, Halifax,
    Br J Psychiatry 206:52-7. 2015
  7. ncbi Brain structural signature of familial predisposition for bipolar disorder: replicable evidence for involvement of the right inferior frontal gyrus
    Tomas Hajek
    Department of Psychiatry, Dalhousie University, Halifax, Canada
    Biol Psychiatry 73:144-52. 2013

Collaborators

Detail Information

Publications7

  1. pmc Risk of mental illness in offspring of parents with schizophrenia, bipolar disorder, and major depressive disorder: a meta-analysis of family high-risk studies
    Daniel Rasic
    To whom correspondence should be addressed Department of Psychiatry, Canada Research Chair in Early Intervention in Psychiatry, Dalhousie University, 5909 Veterans Memorial Lane, Room 3089, Abbie J Lane Memorial Building, Halifax, Nova Scotia B3H 2E2, Canada fax 902 473 4877, E mail
    Schizophr Bull 40:28-38. 2014
    ..We aimed to quantify the risk of mental disorders in offspring and determine whether increased risk extends beyond the disorder present in the parent...
  2. ncbi Gene-environment interactions in common mental disorders: an update and strategy for a genome-wide search
    Rudolf Uher
    Department of Psychiatry, Dalhousie University, 5909 Veterans Memorial Lane, Halifax, B3H 2E2, NS, Canada
    Soc Psychiatry Psychiatr Epidemiol 49:3-14. 2014
    ..Statistical and biological prioritization strategies are proposed to facilitate a systematic discovery of novel gene-environment interactions in genome-wide analyses. ..
  3. pmc The impact of phenotypic and genetic heterogeneity on results of genome wide association studies of complex diseases
    Mirko Manchia
    Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
    PLoS ONE 8:e76295. 2013
    ..These results suggest that accurate phenotype delineation may be more important for detecting true genetic associations than increase in sample size. ..
  4. ncbi Why negative meta-analyses may be false?
    Tomas Hajek
    Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada Prague Psychiatric Center, Department of Psychiatry and Medical Psychology, 3 rd Faculty of Medicine, Charles University, Prague, Czech Republic Electronic address
    Eur Neuropsychopharmacol 23:1307-9. 2013
    ..Over reliance on such meta-analyses may falsely identify certain potentially fruitful research avenues as blind alleys. ..
  5. ncbi Insulin resistance, diabetes mellitus, and brain structure in bipolar disorders
    Tomas Hajek
    1 Department of Psychiatry, Dalhousie University, Halifax, NS, Canada 2 Prague Psychiatric Center, Department of Psychiatry and Medical Psychology, 3rd School of Medicine, Charles University, Prague, Czech Republic
    Neuropsychopharmacology 39:2910-8. 2014
    ..These findings raise the possibility that improving diabetes care among BD subjects and intervening already at the level of prediabetes could slow brain aging in BD. ..
  6. ncbi Insulin resistance and outcome in bipolar disorder
    Cynthia V Calkin
    Cynthia V Calkin, MD, CCFP, FRCPC, Martina Ruzickova, MD, PhD, FRCPC, Department of Psychiatry, Dalhousie University, Halifax, Canada Rudolf Uher, MD, PhD, Department of Psychiatry, Dalhousie University, Halifax, Canada and Institute of Psychiatry, MRC Social, Genetic and Developmental Psychiatry Centre, King s College London, UK Tomas Hajek, MD, PhD, Department of Psychiatry, Dalhousie University, Halifax, Canada and Department of Psychiatry, 3rd School of Medicine, Prague, Charles University, Czech Republic Claire M Slaney, RN, Julie S Garnham, RNBN, Capital District Health Authority, Halifax, Canada M Claire O Donovan, MB, FRCPC, Department of Psychiatry, Dalhousie University, Halifax,
    Br J Psychiatry 206:52-7. 2015
    ..Conclusions Comorbid insulin resistance may be an important factor in resistance to treatment in bipolar disorder. ..
  7. ncbi Brain structural signature of familial predisposition for bipolar disorder: replicable evidence for involvement of the right inferior frontal gyrus
    Tomas Hajek
    Department of Psychiatry, Dalhousie University, Halifax, Canada
    Biol Psychiatry 73:144-52. 2013
    ..Thus, we examined the associations among genetic risk, illness burden, lithium treatment, and brain structure in BD...