Affiliation: Dalhousie University
- Risk of mental illness in offspring of parents with schizophrenia, bipolar disorder, and major depressive disorder: a meta-analysis of family high-risk studiesDaniel Rasic
To whom correspondence should be addressed Department of Psychiatry, Canada Research Chair in Early Intervention in Psychiatry, Dalhousie University, 5909 Veterans Memorial Lane, Room 3089, Abbie J Lane Memorial Building, Halifax, Nova Scotia B3H 2E2, Canada fax 902 473 4877, E mail
Schizophr Bull 40:28-38. 2014..We aimed to quantify the risk of mental disorders in offspring and determine whether increased risk extends beyond the disorder present in the parent...
- Gene-environment interactions in common mental disorders: an update and strategy for a genome-wide searchRudolf Uher
Department of Psychiatry, Dalhousie University, 5909 Veterans Memorial Lane, Halifax, B3H 2E2, NS, Canada
Soc Psychiatry Psychiatr Epidemiol 49:3-14. 2014..Statistical and biological prioritization strategies are proposed to facilitate a systematic discovery of novel gene-environment interactions in genome-wide analyses. ..
- Why negative meta-analyses may be false?Tomas Hajek
Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada Prague Psychiatric Center, Department of Psychiatry and Medical Psychology, 3 rd Faculty of Medicine, Charles University, Prague, Czech Republic Electronic address
Eur Neuropsychopharmacol 23:1307-9. 2013..Over reliance on such meta-analyses may falsely identify certain potentially fruitful research avenues as blind alleys. ..
- The impact of phenotypic and genetic heterogeneity on results of genome wide association studies of complex diseasesMirko Manchia
Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
PLoS ONE 8:e76295. 2013..These results suggest that accurate phenotype delineation may be more important for detecting true genetic associations than increase in sample size. ..