P A Marignani

Summary

Affiliation: Dalhousie University
Country: Canada

Publications

  1. ncbi LKB1, the multitasking tumour suppressor kinase
    P A Marignani
    Dallhousie University, Faculty of Medicine, Department of Biochemistry and Molecular Biology, Halifax, Nova Scotia, Canada
    J Clin Pathol 58:15-9. 2005
  2. ncbi Novel splice isoforms of STRADalpha differentially affect LKB1 activity, complex assembly and subcellular localization
    P A Marignani
    Department of Biochemistry and Molecular Biology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    Cancer Biol Ther 6:1627-31. 2007
  3. ncbi LKB1 associates with Brg1 and is necessary for Brg1-induced growth arrest
    P A Marignani
    Department of Medicine, Division of Signal Transduction, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Biol Chem 276:32415-8. 2001

Detail Information

Publications3

  1. ncbi LKB1, the multitasking tumour suppressor kinase
    P A Marignani
    Dallhousie University, Faculty of Medicine, Department of Biochemistry and Molecular Biology, Halifax, Nova Scotia, Canada
    J Clin Pathol 58:15-9. 2005
    ....
  2. ncbi Novel splice isoforms of STRADalpha differentially affect LKB1 activity, complex assembly and subcellular localization
    P A Marignani
    Department of Biochemistry and Molecular Biology, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    Cancer Biol Ther 6:1627-31. 2007
    ..We report herein the discovery of several novel splice isoforms of STRADalpha that differentially affect the kinase activity, complex assembly, subcellular localization of LKB1 and the activation of the LKB1-dependent AMPK pathway...
  3. ncbi LKB1 associates with Brg1 and is necessary for Brg1-induced growth arrest
    P A Marignani
    Department of Medicine, Division of Signal Transduction, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts 02215, USA
    J Biol Chem 276:32415-8. 2001
    ..The inability of mutants of LKB1 to mediate Brg1-dependent growth arrest may explain the manifestations of Peutz-Jeghers syndrome...