Mary Elizabeth Lynch

Summary

Affiliation: Dalhousie University
Country: Canada

Publications

  1. ncbi request reprint Intravenous adenosine alleviates neuropathic pain: a double blind placebo controlled crossover trial using an enriched enrolment design
    Mary Elizabeth Lynch
    Department of Psychiatry, Dalhousie University, Halifax, NS, Canada
    Pain 103:111-7. 2003
  2. ncbi request reprint A review of the use of methadone for the treatment of chronic noncancer pain
    Mary E Lynch
    Pain Managemaent Unit, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
    Pain Res Manag 10:133-44. 2005
  3. doi request reprint A double-blind, placebo-controlled, crossover pilot trial with extension using an oral mucosal cannabinoid extract for treatment of chemotherapy-induced neuropathic pain
    Mary E Lynch
    Pain Management Unit, Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, Nova Scotia, Canada Department of Anesthesia, Psychiatry and Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada Electronic address
    J Pain Symptom Manage 47:166-73. 2014
  4. ncbi request reprint Preclinical science regarding cannabinoids as analgesics: an overview
    M E Lynch
    Pain Management Unit, Queen Elizabeth II Health Sciences Centre, Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia
    Pain Res Manag 10:7A-14A. 2005
  5. pmc Compound heterozygosity in sodium channel Nav1.7 in a family with hereditary erythermalgia
    Mark E Samuels
    Département de Médicine, Centre de Recherche du CHUM, Local M 5226, Hopital Notre Dame, 1560 rue Sherbrooke Est, Montreal QC H2L 4M1, Canada
    Mol Pain 4:21. 2008
  6. pmc Cannabinoids for treatment of chronic non-cancer pain; a systematic review of randomized trials
    Mary E Lynch
    Department Anesthesia, Psychiatry, Dalhousie University, Halifax, Canada
    Br J Clin Pharmacol 72:735-44. 2011
  7. pmc Research funding for pain in Canada
    Mary E Lynch
    Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
    Pain Res Manag 14:113-5. 2009
  8. pmc Waiting for treatment for chronic pain - a survey of existing benchmarks: toward establishing evidence-based benchmarks for medically acceptable waiting times
    Mary E Lynch
    Department of Psychiatry and Anestesia, Dalhousie University, Halifax, Nova Scotia, Canada
    Pain Res Manag 12:245-8. 2007
  9. ncbi request reprint A systematic review of the effect of waiting for treatment for chronic pain
    Mary E Lynch
    Department of Psychiatry and Anesthesia, Dalhousie University, Halifax, Nova Scotia, Canada
    Pain 136:97-116. 2008
  10. ncbi request reprint A case series of patients using medicinal marihuana for management of chronic pain under the Canadian Marihuana Medical Access Regulations
    Mary E Lynch
    Pain Management Unit, Queen Elizabeth II Health Sciences Center, Halifax, Nova Scotia, Canada
    J Pain Symptom Manage 32:497-501. 2006

Detail Information

Publications17

  1. ncbi request reprint Intravenous adenosine alleviates neuropathic pain: a double blind placebo controlled crossover trial using an enriched enrolment design
    Mary Elizabeth Lynch
    Department of Psychiatry, Dalhousie University, Halifax, NS, Canada
    Pain 103:111-7. 2003
    ..The results of this study support previous reports that indicate intravenous adenosine alleviates neuropathic pain and hyperalgesia...
  2. ncbi request reprint A review of the use of methadone for the treatment of chronic noncancer pain
    Mary E Lynch
    Pain Managemaent Unit, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
    Pain Res Manag 10:133-44. 2005
    ..The present review is intended to educate physicians interested in adding methadone to their armamentarium for assisting patients with moderate to severe pain...
  3. doi request reprint A double-blind, placebo-controlled, crossover pilot trial with extension using an oral mucosal cannabinoid extract for treatment of chemotherapy-induced neuropathic pain
    Mary E Lynch
    Pain Management Unit, Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, Nova Scotia, Canada Department of Anesthesia, Psychiatry and Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada Electronic address
    J Pain Symptom Manage 47:166-73. 2014
    ..Recent preclinical studies demonstrate that cannabinoid agonists suppress established chemotherapy-evoked neuropathy...
  4. ncbi request reprint Preclinical science regarding cannabinoids as analgesics: an overview
    M E Lynch
    Pain Management Unit, Queen Elizabeth II Health Sciences Centre, Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia
    Pain Res Manag 10:7A-14A. 2005
    ..The present article presents an overview of the preclinical science...
  5. pmc Compound heterozygosity in sodium channel Nav1.7 in a family with hereditary erythermalgia
    Mark E Samuels
    Département de Médicine, Centre de Recherche du CHUM, Local M 5226, Hopital Notre Dame, 1560 rue Sherbrooke Est, Montreal QC H2L 4M1, Canada
    Mol Pain 4:21. 2008
    ..This is the second reported study of potential compound heterozygosity for coding polymorphisms in Nav1.7, the first being in a patient with paroxysmal extreme pain disorder...
  6. pmc Cannabinoids for treatment of chronic non-cancer pain; a systematic review of randomized trials
    Mary E Lynch
    Department Anesthesia, Psychiatry, Dalhousie University, Halifax, Canada
    Br J Clin Pharmacol 72:735-44. 2011
    ..The context of the need for additional treatments for chronic pain is reviewed. Further large studies of longer duration examining specific cannabinoids in homogeneous populations are required...
  7. pmc Research funding for pain in Canada
    Mary E Lynch
    Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
    Pain Res Manag 14:113-5. 2009
    ..9 million. This is less than 1% of the total funding from the Canadian Institutes of Health Research and 0.25% of the total funding for health research...
  8. pmc Waiting for treatment for chronic pain - a survey of existing benchmarks: toward establishing evidence-based benchmarks for medically acceptable waiting times
    Mary E Lynch
    Department of Psychiatry and Anestesia, Dalhousie University, Halifax, Nova Scotia, Canada
    Pain Res Manag 12:245-8. 2007
    ..This will facilitate advocacy for improved access to appropriate care for people suffering from chronic pain around the world...
  9. ncbi request reprint A systematic review of the effect of waiting for treatment for chronic pain
    Mary E Lynch
    Department of Psychiatry and Anesthesia, Dalhousie University, Halifax, Nova Scotia, Canada
    Pain 136:97-116. 2008
    ..Most important is the need to improve access to appropriate care for patients with chronic pain, an escalating public health care problem with significant human and economic costs...
  10. ncbi request reprint A case series of patients using medicinal marihuana for management of chronic pain under the Canadian Marihuana Medical Access Regulations
    Mary E Lynch
    Pain Management Unit, Queen Elizabeth II Health Sciences Center, Halifax, Nova Scotia, Canada
    J Pain Symptom Manage 32:497-501. 2006
    ..Limitations of the study include self-selection bias, small size, and lack of a control group. The need for further study using controlled trials is discussed along with an overview of the MMAR program...
  11. pmc The pharmacotherapy of chronic pain: a review
    Mary E Lynch
    Department of Psychiatry, Dalhousie University, Halifax, Canada
    Pain Res Manag 11:11-38. 2006
    ....
  12. ncbi request reprint Topical amitriptyline and ketamine in neuropathic pain syndromes: an open-label study
    Mary Elizabeth Lynch
    Pain Management Unit, Queen Elizabeth II Health Sciences Centre and Department Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada
    J Pain 6:644-9. 2005
    ..There was no significant systemic absorption of amitriptyline or ketamine...
  13. ncbi request reprint Topical 2% amitriptyline and 1% ketamine in neuropathic pain syndromes: a randomized, double-blind, placebo-controlled trial
    Mary E Lynch
    Pain Management Unit, Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada
    Anesthesiology 103:140-6. 2005
    ..A double-blind, randomized, placebo-controlled 3-week study evaluated the efficacy of topical 2% amitriptyline, 1% ketamine, and a combination of both in treating patients with neuropathic pain...
  14. ncbi request reprint A pilot study examining topical amitriptyline, ketamine, and a combination of both in the treatment of neuropathic pain
    M E Lynch
    Pain Management Unit, Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, Nova Scotia
    Clin J Pain 19:323-8. 2003
    ..This is a pilot study providing initial information regarding the use of novel topical preparations containing amitriptyline (AMI), ketamine (KET), and a combination of both in the treatment of neuropathic pain...
  15. pmc Antidepressants as analgesics: a review of randomized controlled trials
    M E Lynch
    Queen Elizabeth II Health Sciences Centre and Department of Psychiatry, Dalhousie University, Halifax, NS
    J Psychiatry Neurosci 26:30-6. 2001
    ....
  16. doi request reprint The pharmacotherapy of chronic pain
    Mary E Lynch
    Pain Management Unit, Queen Elizabeth II Health Sciences Centre, Department of Anesthesiology, Psychiatry, and Pharmacology, Dalhousie University, 4th Floor Dickson Centre, Room 4086, Halifax, NS B3H 1V7, Canada
    Rheum Dis Clin North Am 34:369-85. 2008
    ..For moderate to severe pain, one would initiate a trial of chronic opioid earlier. Cannabinoids and topicals may also be appropriate as single agents or in combination...